Retargeting Clostridium difficile Toxin B to Neuronal Cells as a Potential Vehicle for Cytosolic Delivery of Therapeutic Biomolecules to Treat Botulism by Greice Krautz-Peterson, Yongrong Zhang, Kevin Chen, George A. Oyler, Hanping Feng, Charles B. Shoemaker

“…Botulinum neurotoxins (BoNTs) deliver a protease to neurons which can cause a flaccid paralysis called botulism. Development of botulism antidotes will require neuronal delivery of agents that inhibit or destroy the BoNT protease. …”
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Serotonin Syndrome after Sertraline Overdose in a Child: A Case Report by Joana Grenha, Ana Garrido, Hernani Brito, Maria José Oliveira, Fátima Santos

“…As the patient presented a severe insomnia and a progressive rhabdomyolysis, she was transferred to pediatric intensive care unit (ICU), where she was under treatment with cyproheptadine, mechanical ventilation, and muscular paralysis for 11 days. She was discharged from hospital a few days later with no neurological sequelae. …”
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Goal-Oriented Respiratory Management for Critically Ill Patients with Acute Respiratory Distress Syndrome by Carmen Sílvia Valente Barbas, Gustavo Faissol Janot Matos, Marcelo Britto Passos Amato, Carlos Roberto Ribeiro Carvalho

“…Rapid administration of antibiotics and resuscitative measures in case of sepsis and septic shock associated with protective ventilatory strategies and early short-term paralysis associated with differential ventilatory techniques (recruitment maneuvers with adequate positive end-expiratory pressure titration, prone position, and new extracorporeal membrane oxygenation techniques) in severe ARDS can help improve its prognosis. …”
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Unilateral Hypoglossal Nerve Palsy after Use of the Laryngeal Mask Airway Supreme by Kenichi Takahoko, Hajime Iwasaki, Tomoki Sasakawa, Akihiro Suzuki, Hideki Matsumoto, Hiroshi Iwasaki

“…Conservative treatment was chosen and the paralysis recovered completely after 5 months. Conclusion. …”
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Paroxysmal Laryngospasm: A Rare Condition That Respiratory Physicians Must Distinguish from Other Diseases with a Chief Complaint of Dyspnea by Yu Bai, Xi-Rui Jing, Yun Xia, Xiao-Nan Tao

“…One patient with left vocal cord paralysis experienced complete relief after specialist treatment by an otorhinolaryngologist. …”
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Giant Arteriovenous Malformation of the Neck by P. A. Dieng, P. S. Ba, M. Gaye, S. Diatta, M. S. Diop, E. Sene, A. G. Ciss, A. Ndiaye, M. Ndiaye

“…In postoperative period the patient presented a peripheral facial paralysis which completely decreased within 10 days. …”
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Guillain-Barré Syndrome after H1N1 Shot in Pregnancy: Maternal and Fetal Care in the Third Trimester—Case Report by Felipe Favorette Campanharo, Eduardo Felix Martins Santana, Stephanno Gomes Pereira Sarmento, Rosiane Mattar, Sue Yazaki Sun, Antonio Fernandes Moron

“…We presented a case of a 36-year-old pregnant woman that was immunized to H1N1 in the last trimester; 10 days later she developed shoulder and lumbar spine's pain, limbs weakness and facial paralysis with unfavorable clinical evolution and was submitted to intensive therapy care. …”
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Adult classic Bartter syndrome: a case report with 5-year follow-up and literature review by Le Jiang, Dongmei Li, Qiansha Guo, Yunfeng Li, Lei Zan, Rihan Ao

“…This case report describes the findings in a 20-year-old man who was admitted with hypokalemic paralysis, with clinical manifestations were similar to those of Gitelman syndrome (GS); however, the patient was later diagnosed to have BS Type 3 through genetic testing (NM_000085.4 (CLCNKB): c.1052G>T). …”
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Balloon-Assisted Percutaneous Thrombin Injection for Treatment of Iatrogenic Left Subclavian Artery Pseudoaneurysm in a Critically Ill COVID-19 Patient by Hassan Al-Thani, Ahmed Hussein, Ahmed Sadek, Ali Barah, Ayman El-Menyar

“…The patient declined surgical reconstruction of the brachial plexus, and the flaccid paralysis of the arm did not recover during the follow-up. …”
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Stability and neurotoxic impact of organophosphate pesticides in aqueous environments by Vladan J. Anićijević, Tamara Tasić, Vedran Milanković, Radovan M. Karkalić, Tamara D. Lazarević Pašti

“…Their toxic effects manifest by acetylcholine accumulation in the nerve synapses and can lead to paralysis or death. Organo-thiophosphate pesticides (OPs) are used in large quantities. …”
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A data ensemble-based approach for detecting vocal disorders using replicated acoustic biomarkers from electroglottography by Lizbeth Naranjo, Carlos J. Pérez, Daniel F. Merino

“…Experiments on SVD demonstrated the robustness of the proposed methodology across different vowels in classifying healthy individuals, patients with laryngitis, and those with vocal fold paralysis. Conclusion: The data ensemble-based approaches developed effectively manage the dependent nature of EGG measurements, enhancing the detection and classification of vocal disorders. …”
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Neurologic Complications Associated with Sjögren’s Disease: Case Reports and Modern Pathogenic Dilemma by Michele Colaci, Giulia Cassone, Andreina Manfredi, Marco Sebastiani, Dilia Giuggioli, Clodoveo Ferri

“…We reported 2 cases: the first one was a 40-year-old woman who developed neuritis of the left optic nerve as presenting symptom few years before the diagnosis of SS; the second was a 54-year-old woman who presented a paralysis of the right phrenic nerve 7 years after the SS onset. …”
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Sporadic ALS hiPSC-derived motor neurons show axonal defects linked to altered axon guidance pathways by Lisha Ye, Katarina Stoklund Dittlau, Adria Sicart, Rekin'’s Janky, Philip Van Damme, Ludo Van Den Bosch

“…Amyotrophic lateral sclerosis (ALS) is a devastating neurodegenerative disorder characterized by the selective and progressive loss of motor neurons, leading to gradual paralysis and death within 2 to 5 years after diagnosis. …”
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Tick-borne encephalitis: students’ attitude and knowledge analysis by R. Mineikytė, G. Navickaitė, J. Valaikienė

“…The most commonly named complications of TBE were paralysis and paresis – 327 (81%) students. 3 respondents (1%) thought that TBE is a dis ease without any complications. …”
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Exploration of analgesic and anthelmintic activities of Artocarpus chaplasha ROXB. leaves supported by in silico molecular docking by S M Sohag, Sharmin Nur Toma, Md. Niaj Morshed, Md. Al Imran Imon, Md. Monirul Islam, Md. Ibnul Piash, Naznin Shahria, Imran Mahmud

“…In the anthelmintic tests, a 100 mg/mL concentration resulted in the lowest paralysis and death times of 14.03 and 18.03 mins, respectively. …”
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Pleomorphic Adenoma of the Parotid: Extracapsular Dissection Compared with Superficial Parotidectomy—A 10-Year Retrospective Cohort Study by Maria Giulia Cristofaro, Eugenia Allegra, Amerigo Giudice, Walter Colangeli, Davide Caruso, Ida Barca, Mario Giudice

“…Transient facial nerve injury and facial paralysis were significantly more frequent after SP than after ED (P=0.001 and P=0.065, resp.). …”
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Systematic Review of Electroacupuncture for Bell’s Palsy by Min-seok Go, Seong-hyun Lee, Ji-eun Oh, Seung-chul Yeom, Tae-ha Kwon, Sae-young Bong, Cha-young Lee, Hye-jin Shin

“…Bell’s palsy, characterized by sudden-onset facial paralysis of unknown cause, is the most prevalent form of its kind, and electroacupuncture (EA) is one of the popular treatments in Korea. …”

A systematic review of the worldwide prevalence of survivors of poliomyelitis reported in 31 studies by Alice Theadom, Shivanthi Balalla, Kelly M Jones, Valery L Feigin, Gordon Jackman

“…Background Accurate prevalence figures estimating the number of survivors of poliomyelitis (disease causing acute flaccid paralysis) following poliovirus infection are not available. …”
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Deciphering In Vitro and In Vivo Pharmacological Properties of Seed and Fruit Extracts of Flacourtia jangomas (Lour.) Raeusch by Farhana Alam Ripa, Fowzia Alam, Fahmida Haque Riya, Yesmin Begum, Sharmin Akter Eti, Nusratun Nahar, Zebunnesa Ahmed, Sabrina Sharmin

“…All samples displayed notable anthelmintic activity by reducing Pheretima posthuma paralysis and death time in a dose-dependent manner compared to albendazole. …”
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Syzygium malaccense leaf extract-mediated silver nanoparticles: synthesis, characterization, and biomedical evaluation in Caenorhabditis elegans and lung cancer cell line by Santosh Mallikarjun Bhavi, Bothe Thokchom, Sapam Riches Singh, Sukesh Kumar Bajire, Rajesh P. Shastry, B. S. Srinath, Shivanand S. Bhat, Kotresha Dupadahalli, Chandramohan Govindasamy, Swati Ravi Chalekar, B. P. Harini, Ramesh Babu Yarajarla

“…Additionally, SM-AgNPs increased Caenorhabditis elegans survival and reduced paralysis under pathogenic bacterial exposure. This study demonstrates the potential of SM-AgNPs in biomedical applications, emphasizing selective anticancer activity and antimicrobial effects in vivo.…”
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