Exome sequencing in Nigerian children with early‐onset epilepsy syndromes by Ibitayo Abigail Ademuwagun, Yagoub Adam, Solomon Oladapo Rotimi, Steffen Syrbe, Maximilian Radtke, Julia Hentschel, Johannes R. Lemke, Ezekiel Adebiyi

“…Molecular analysis included DNA fragmentation, ligation, target enrichment, library preparation, and whole‐exome sequencing. Computational analysis involved variant calling, curation, and classification using specialized tools and databases. …”
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RISET PRAKTIK EKSPERIMENTAL LAS BUSUR DENGAN MATERIAL AS STAINLESS STEEL UNTUK PENCIPTAAN BENTUK KATAK POHON by Miky Endro Santoso

“…The research objective was to determine the various materials and equipment used in welding with arc welding techniques; identify the stages of the implementation of creation from the preparation stage, the working stage, and the final stage, so that the work creation process runs smoothly. …”
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In-Situ Electrospinning Dressings Loaded with Kaempferol for Reducing MMP9 to Promote Diabetic Ulcer Healing by Li J, Meng H, Guo W, Zhou L, Wu S, Gao G, Liu Q, You D, Qu W

“…The high porosity of biomaterials induces more M2 macrophages, while the natural compound kaempferol inhibits the expression of matrix metalloproteinase 9 (MMP9) and thus inhibits the associated inflammatory and immunological responses.Methods: portable electrospinning dressings (PEDs) were prepared from the spinning solution using a portable electrospinning device. …”
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Identification of most motivating resource for estimation of social hierarchy in water buffaloes by Sunil Dutt, M.L. Kamboj

“…A socio-metric matrix of all agonistic interactions was prepared, and pooled data was analyzed using one-way ANOVA in SPSS version 22. …”
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Pyrrolizine-5-carboxamides: Exploring the impact of various substituents on anti-inflammatory and anticancer activities by Gouda Ahmed M., Abdelazeem Ahmed H., Abdalla Ashraf N., Ahmed Muhammad

“…Towards optimization of the pyrrolizine-5-carboxamide scaffold, a novel series of six derivatives (4a-c and 5a-c) was prepared and evaluated for their anti-inflammatory, analgesic and anticancer activities. …”
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Development and Evaluation of Aloperine-Loaded Nanostructured Lipid Carriers for the Treatment of Pulmonary Arterial Hypertension by Liu H, Liu S, Ma P, Ma L, Liu Y, Zhao F, Zhou R

“…Through a series of experiments including single-factor experimentation, transmission electron microscopy, high-performance liquid chromatography, in vivo pharmacokinetics, and tissue distribution studies, we assessed the physicochemical properties, drug release profiles, and in vitro and in vivo performance of this novel nanocarrier.Results: The prepared aloperine-loaded NLCs exhibited a milky white and translucent suspension appearance, presenting a quasi-spherical shape under a transmission electron microscope, with an average particle size of (509.48± 30.04) nm and an entrapment efficiency of (64.18± 1.14)%. …”
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Impact of geochemical reactivity on desulphation requirements in a sandstone reservoir containing carbonate and sulphate minerals by Ali M. Al-Behadili, Eric J. Mackay

“…There are various factors affecting the system, such as water injection well and production well flow rates and flow through the reservoir, and also compositional effects due to use of Full Sulphate Seawater (FSSW) or Low Sulphate Seawater (LSSW), and due to variations in temperature and the concentration of CO2 in the oil phase. In this study, as preparation for addition of geochemistry to a full field 3D history matched model, we include geochemical reactions in a 1D model that has the field pressure, temperature and fluid properties, to test the impact of the various potential reactions in a simple system. …”
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Development and Assessment of a Color-Variable Chlorine Dioxide Slow-Releasing Card for Litchi Preservation by Li Guo, Guang Wu, Qingchun Yin, Lin Luo, Hao Deng

“…The optimal ClO₂ slow-releasing card was prepared as follows: Card A was soaked in 2.5 mol/L NaClO₂ and 0.3 mol/L CaCl₂. …”
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Natural Products as Sources of Antimalarial Drugs: Ethnobotanical and Ethnopharmacological Studies by Oluwole Solomon Oladeji, Abimbola Peter Oluyori, Deborah Temitope Bankole, Tokunbo Yemisi Afolabi

“…The most cited plants are Azadirachta indica (42), Mangifera indica (38), Carica papaya (28), Cymbopogon citratus (27), Cassia fistula (15), Morinda lucida (14), Anacardium occidentale and Vernonia amygdalina (13 each), Helianthus annuus (11), Enantia chlorantha (10), and Moringa oleifera (9) A total of 105 citations were recorded for the plant parts used (leaf (46), bark (17), fruits (9), root (9), latex (11), stem (11), and inflorescence (2)) while decoction (59%), maceration (25%), infusion (9%), and exudation (7%) were the methods of preparation. Use Values (UVs) of 0.47 to 0.11 were recorded for the frequently used antimalarial plants. …”
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The Potential Clinical Utility of the Customized Large Language Model in Gastroenterology: A Pilot Study by Eun Jeong Gong, Chang Seok Bang, Jae Jun Lee, Jonghyung Park, Eunsil Kim, Subeen Kim, Minjae Kimm, Seoung-Ho Choi

“…<b>Method:</b> We established a customized GPT with the BM25 algorithm using Open AI’s GPT-4o model, which allows it to produce responses in the context of specific documents including textbooks of internal medicine (in English) and gastroenterology (in Korean). Also, we prepared a conventional ChatGPT 4o (accessed on 16 October 2024) access. …”
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Epidemiology of Lumbar Puncture and the Validity of Meningeal Signs in Predicting Meningitis in Children: A Cross-sectional Study by Mehjabin, Shiji Joseph, Arun Ravi, Kalyani Pillai

“…The records of paediatric patients (aged 1 month to 12 years) who underwent LP during the one year from August 2018 to July 2019 at the centre were collected. A checklist was prepared for all the patients, where demographic data, clinical presentations, findings of CSF, and blood analysis were recorded. …”
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Reloading mechanical characteristics of cemented tailings backfill after dynamic loading action by Xuepeng SONG, Bowen FAN, Shi WANG, Hongwei ZHANG

“…Therefore, in this paper, the dynamic damage filling body considering the magnitude of impact amplitude is prepared based on the split Hopkinson press bar system (SHPB), and the simulation of filling body blasting disturbance is realized. …”
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Biological, cytomorphological and karyological heterogeneity of transformed cell lines derived from domestic pig (Sus scrofa L.) organs by B. L. Manin, E. A. Trofimova, V. L. Gavrilova, O. S. Puzankova

“…Also, a procedure for preparation of new diploid cell culture from porcine spleen (SSs – Splеen Sus scrofa) is described. …”
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Gonadotropin Releasing Hormone Agonists Combined with Hormone Replacement Therapy Significantly Improves Reproductive Outcomes for Patients with Thin Endometrium and Intramural Fib... by Wei L, Tian B, Wang S, Xu S, Zhang C

“…Patients were stratified into three groups based on the endometrial preparation protocol: the natural cycle (NC) group (n=96), the hormone replacement therapy (HRT) group (n=180), and the GnRH-a-HRT group (n=84). …”
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Malaria and Geohelminthiasis Coinfections in Expectant Women: Effect on Maternal Health and Birth Outcomes in a Malaria Endemic Region in Kenya by Wekesa Antony Wanyonyi, Chrispinus Siteti Mulambalah, David H. Mulama, Elizabeth Omukunda, Darwin Injete Siteti

“…Haemoglobin and eosinophils levels were determined by coulter counter while malaria parasitemia levels and red blood cell morphology were assessed by preparing and observing blood smears under the microscope. …”
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Beyond Chemistry: Investigating the Physical, Pharmacological, and Computational Aspects of Polyoxometalate Integrated Solid Lipid Nanoparticles for Cancer Treatment by Khan R, Tulain UR, Shah HS, Usman F, Chohan TA, Iqbal J, Kazi M, Ijaz M, Erum A, Malik NS, Mahmood A

“…Riffat Khan,1 Ume Ruqia Tulain,1 Hamid Saeed Shah,2 Faisal Usman,3 Tahir Ali Chohan,2 Jamshed Iqbal,4 Mohsin Kazi,5 Muhammad Ijaz,6 Alia Erum,1 Nadia Shamshad Malik,7 Arshad Mahmood8,9 1Faculty of Pharmacy, University of Sargodha, Sargodha, 40100, Pakistan; 2Institute of Pharmaceutical Sciences, University of Veterinary and Animal Sciences, Lahore, 54000, Pakistan; 3Department of Pharmaceutics, Faculty of Pharmacy, Bahauddin Zakariya University, Multan, 66000, Pakistan; 4Centre for Advanced Drug Research, COMSATS University Islamabad, Abbottabad Campus, Abbottabad, 22060, Pakistan; 5Department of Pharmaceutics, College of Pharmacy, King Saud University, Riyadh, 11451, Saudi Arabia; 6Department of Pharmacy, COMSATS University Islamabad, Lahore Campus, Lahore, Pakistan; 7Faculty of Pharmacy, Capital University of Science and Technology, Islamabad, Pakistan; 8College of Pharmacy, Al-Ain University, Abu Dhabi Campus, Abudhabi, United Arab Emirates; 9AAU Health and Biomedical Research Center, Al Ain University, Abu Dhabi, United Arab EmiratesCorrespondence: Ume Ruqia Tulain; Muhammad Ijaz, Email umeruqia.tulain@uos.edu.pk; drmijaz@cuilahore.edu.pkPurpose: The solid lipid nanoparticles of transitional metal complexes (POMs) were prepared with natural lipids with the aim of developing a safer therapeutic approach for cancer treatment.Methods: Natural lipids were used to create solid lipid nanoparticles containing transitional metal complexes (POMs).Results: The nanoparticles had displayed appreciable entrapment and loading percentage of P5W30. …”
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Estudio experimental del empuje sobre estructuras de contención en suelos reforzados con geomallas Experimental study of the lateral earth pressure on retaining structures in soils... by Lissette Ruiz-Tagle, Felipe Villalobos

“…The experimental apparatus and the measurement instruments as well as the soil and the sample preparation and the geogrids used, are described. In a first stage of research, samples without reinforcing are tested and the results are compared with those from classic earth pressure theories. …”
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Innovative MOF-enhanced electroanalytical approach for sensitive sunitinib malate detection in renal carcinoma patients using CuO/lanthanum MOF-modified carbon paste electrode by Azza H. Rageh, Mohamed I. Said, Asmaa Abdeltawab, Fatma A.M. Abdel-aal

“…Moreover, the modified electrode based on LaNDC-MOF (Conv.) exhibited better electrocatalytic activity and improved sensitivity towards the oxidation of SUN than that prepared through solvothermal route. Various experimental parameters, including accumulation potential, accumulation time, and pH of the supporting electrolyte, were optimized to obtain the best analytical performance. …”
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Assessing Durability and Stability of Calcium Sulfoaluminate Cement-Stabilized Soils Under Cyclic Wet–Dry Conditions by Ayesha Rauf, Sung-Woo Moon, Alfrendo Satyanaga, Jong Kim

“…Various samples were prepared with cement contents of 3%, 5%, 7%, and 10%, corresponding to the optimum moisture content. …”
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Exosomes Derived from CXCR4-Overexpressing BMSC Promoted Activation of Microvascular Endothelial Cells in Cerebral Ischemia/Reperfusion Injury by Xutong Li, Ye Zhang, Yong Wang, Dan Zhao, Chengcheng Sun, Shaoting Zhou, Dongsheng Xu, Jing Zhao

“…The acute middle cerebral artery occlusion (MCAO) model was prepared, ExoCXCR4 were injected into the rats, and behavioral changes were analyzed. …”
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