RNA polymerase II-mediated rDNA transcription mediates rDNA copy number expansion in Drosophila. by George J Watase, Yukiko M Yamashita

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Differential impact of the HEN1 homolog HENN-1 on 21U and 26G RNAs in the germline of Caenorhabditis elegans. by Leonie M Kamminga, Josien C van Wolfswinkel, Maartje J Luteijn, Lucas J T Kaaij, Marloes P Bagijn, Alexandra Sapetschnig, Eric A Miska, Eugene Berezikov, René F Ketting

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Pangenome graph analysis reveals extensive effector copy-number variation in spinach downy mildew. by Petros Skiadas, Sofía Riera Vidal, Joris Dommisse, Melanie N Mendel, Joyce Elberse, Guido Van den Ackerveken, Ronnie de Jonge, Michael F Seidl

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Identification of neural outgrowth genes using genome-wide RNAi. by Katharine J Sepp, Pengyu Hong, Sofia B Lizarraga, Judy S Liu, Luis A Mejia, Christopher A Walsh, Norbert Perrimon

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Rapid-throughput skeletal phenotyping of 100 knockout mice identifies 9 new genes that determine bone strength. by J H Duncan Bassett, Apostolos Gogakos, Jacqueline K White, Holly Evans, Richard M Jacques, Anne H van der Spek, Sanger Mouse Genetics Project, Ramiro Ramirez-Solis, Edward Ryder, David Sunter, Alan Boyde, Michael J Campbell, Peter I Croucher, Graham R Williams

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Multiple regulatory systems coordinate DNA replication with cell growth in Bacillus subtilis. by Heath Murray, Alan Koh

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Understanding Biases in Ribosome Profiling Experiments Reveals Signatures of Translation Dynamics in Yeast. by Jeffrey A Hussmann, Stephanie Patchett, Arlen Johnson, Sara Sawyer, William H Press

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Nutrient Control of Yeast Gametogenesis Is Mediated by TORC1, PKA and Energy Availability. by Hilla Weidberg, Fabien Moretto, Gianpiero Spedale, Angelika Amon, Folkert J van Werven

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Loss of expression and promoter methylation of SLIT2 are associated with sessile serrated adenoma formation. by Andrew D Beggs, Angela Jones, Neil Shepherd, Abed Arnaout, Caroline Finlayson, A Muti Abulafi, Dion G Morton, Glenn M Matthews, Shirley V Hodgson, Ian P M Tomlinson

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Essential role of chromatin remodeling protein Bptf in early mouse embryos and embryonic stem cells. by Joseph Landry, Alexei A Sharov, Yulan Piao, Lioudmila V Sharova, Hua Xiao, Eileen Southon, Jennifer Matta, Lino Tessarollo, Ying E Zhang, Minoru S H Ko, Michael R Kuehn, Terry P Yamaguchi, Carl Wu

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RNA Polymerase III Output Is Functionally Linked to tRNA Dimethyl-G26 Modification. by Aneeshkumar G Arimbasseri, Nathan H Blewett, James R Iben, Tek N Lamichhane, Vera Cherkasova, Markus Hafner, Richard J Maraia

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Pain genes. by Tom Foulkes, John N Wood

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Heteroplasmic mitochondrial DNA variants in cardiovascular diseases. by Claudia Calabrese, Angela Pyle, Helen Griffin, Jonathan Coxhead, Rafiqul Hussain, Peter S Braund, Linxin Li, Annette Burgess, Patricia B Munroe, Louis Little, Helen R Warren, Claudia Cabrera, Alistair Hall, Mark J Caulfield, Peter M Rothwell, Nilesh J Samani, Gavin Hudson, Patrick F Chinnery

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Long-range regulatory polymorphisms affecting a GABA receptor constitute a quantitative trait locus (QTL) for social behavior in Caenorhabditis elegans. by Andres Bendesky, Jason Pitts, Matthew V Rockman, William C Chen, Man-Wah Tan, Leonid Kruglyak, Cornelia I Bargmann

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Functional analysis of CYP4B1 enzymes from apes and humans uncovers evolutionary hot spots for adaptations of the catalytical function. by Saskia Hüsken, Annika Röder, Johannes Ptok, Anne E Meyer, Mats Georg, Yannick Schwarz, Christian Roos, Kerstin Mätz-Rensing, Michael C Hutter, Doreen M Floss, Allan E Rettie, Marco Girhard, Helmut Hanenberg, Constanze Wiek

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Chlamydomonas DYX1C1/PF23 is essential for axonemal assembly and proper morphology of inner dynein arms. by Ryosuke Yamamoto, Jagan M Obbineni, Lea M Alford, Takahiro Ide, Mikito Owa, Juyeon Hwang, Takahide Kon, Kazuo Inaba, Noliyanda James, Stephen M King, Takashi Ishikawa, Winfield S Sale, Susan K Dutcher

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Genetic and functional analyses of SHANK2 mutations suggest a multiple hit model of autism spectrum disorders. by Claire S Leblond, Jutta Heinrich, Richard Delorme, Christian Proepper, Catalina Betancur, Guillaume Huguet, Marina Konyukh, Pauline Chaste, Elodie Ey, Maria Rastam, Henrik Anckarsäter, Gudrun Nygren, I Carina Gillberg, Jonas Melke, Roberto Toro, Beatrice Regnault, Fabien Fauchereau, Oriane Mercati, Nathalie Lemière, David Skuse, Martin Poot, Richard Holt, Anthony P Monaco, Irma Järvelä, Katri Kantojärvi, Raija Vanhala, Sarah Curran, David A Collier, Patrick Bolton, Andreas Chiocchetti, Sabine M Klauck, Fritz Poustka, Christine M Freitag, Regina Waltes, Marnie Kopp, Eftichia Duketis, Elena Bacchelli, Fiorella Minopoli, Liliana Ruta, Agatino Battaglia, Luigi Mazzone, Elena Maestrini, Ana F Sequeira, Barbara Oliveira, Astrid Vicente, Guiomar Oliveira, Dalila Pinto, Stephen W Scherer, Diana Zelenika, Marc Delepine, Mark Lathrop, Dominique Bonneau, Vincent Guinchat, Françoise Devillard, Brigitte Assouline, Marie-Christine Mouren, Marion Leboyer, Christopher Gillberg, Tobias M Boeckers, Thomas Bourgeron

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A mechanism of gene amplification driven by small DNA fragments. by Kuntal Mukherjee, Francesca Storici

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Two new Loci for body-weight regulation identified in a joint analysis of genome-wide association studies for early-onset extreme obesity in French and german study groups. by André Scherag, Christian Dina, Anke Hinney, Vincent Vatin, Susann Scherag, Carla I G Vogel, Timo D Müller, Harald Grallert, H-Erich Wichmann, Beverley Balkau, Barbara Heude, Marjo-Riitta Jarvelin, Anna-Liisa Hartikainen, Claire Levy-Marchal, Jacques Weill, Jérôme Delplanque, Antje Körner, Wieland Kiess, Peter Kovacs, Nigel W Rayner, Inga Prokopenko, Mark I McCarthy, Helmut Schäfer, Ivonne Jarick, Heiner Boeing, Eva Fisher, Thomas Reinehr, Joachim Heinrich, Peter Rzehak, Dietrich Berdel, Michael Borte, Heike Biebermann, Heiko Krude, Dieter Rosskopf, Christian Rimmbach, Winfried Rief, Tobias Fromme, Martin Klingenspor, Annette Schürmann, Nadja Schulz, Markus M Nöthen, Thomas W Mühleisen, Raimund Erbel, Karl-Heinz Jöckel, Susanne Moebus, Tanja Boes, Thomas Illig, Philippe Froguel, Johannes Hebebrand, David Meyre

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Analysis of meiosis in SUN1 deficient mice reveals a distinct role of SUN2 in mammalian meiotic LINC complex formation and function. by Jana Link, Monika Leubner, Johannes Schmitt, Eva Göb, Ricardo Benavente, Kuan-Teh Jeang, Rener Xu, Manfred Alsheimer

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