Von Hippel-Lindau (VHL) inactivation in sporadic clear cell renal cancer: associations with germline VHL polymorphisms and etiologic risk factors. by Lee E Moore, Michael L Nickerson, Paul Brennan, Jorge R Toro, Erich Jaeger, Jessica Rinsky, Summer S Han, David Zaridze, Vsevolod Matveev, Vladimir Janout, Hellena Kollarova, Vladimir Bencko, Marie Navratilova, Neonilia Szeszenia-Dabrowska, Dana Mates, Laura S Schmidt, Petra Lenz, Sara Karami, W Marston Linehan, Maria Merino, Stephen Chanock, Paolo Boffetta, Wong-Ho Chow, Frederic M Waldman, Nathaniel Rothman

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Meiosis-specific stable binding of augmin to acentrosomal spindle poles promotes biased microtubule assembly in oocytes. by Nathalie Colombié, A Agata Głuszek, Ana M Meireles, Hiroyuki Ohkura

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Patient-derived iPSCs link elevated mitochondrial respiratory complex I function to osteosarcoma in Rothmund-Thomson syndrome. by Brittany E Jewell, An Xu, Dandan Zhu, Mo-Fan Huang, Linchao Lu, Mo Liu, Erica L Underwood, Jun Hyoung Park, Huihui Fan, Julian A Gingold, Ruoji Zhou, Jian Tu, Zijun Huo, Ying Liu, Weidong Jin, Yi-Hung Chen, Yitian Xu, Shu-Hsia Chen, Nino Rainusso, Nathaniel K Berg, Danielle A Bazer, Christopher Vellano, Philip Jones, Holger K Eltzschig, Zhongming Zhao, Benny Abraham Kaipparettu, Ruiying Zhao, Lisa L Wang, Dung-Fang Lee

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Autozygome sequencing expands the horizon of human knockout research and provides novel insights into human phenotypic variation. by Ahmed B Alsalem, Anason S Halees, Shamsa Anazi, Shomoukh Alshamekh, Fowzan S Alkuraya

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Memory-like states created by the first ethanol experience are encoded into the Drosophila mushroom body learning and memory circuitry in an ethanol-specific manner. by Caleb Larnerd, Maria Nolazco, Ashley Valdez, Vanessa Sanchez, Fred W Wolf

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Identification of novel genes responsible for a pollen killer present in local natural populations of Arabidopsis thaliana. by Anthony Ricou, Matthieu Simon, Rémi Duflos, Marianne Azzopardi, Fabrice Roux, Françoise Budar, Christine Camilleri

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Principles of carbon catabolite repression in the rice blast fungus: Tps1, Nmr1-3, and a MATE-family pump regulate glucose metabolism during infection. by Jessie Fernandez, Janet D Wright, David Hartline, Cristian F Quispe, Nandakumar Madayiputhiya, Richard A Wilson

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Fitness landscapes of human microsatellites. by Ryan J Haasl, Bret A Payseur

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Domain-adaptive neural networks improve supervised machine learning based on simulated population genetic data. by Ziyi Mo, Adam Siepel

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Regulatory logic of endogenous RNAi in silencing de novo genomic conflicts. by Jeffrey Vedanayagam, Ching-Jung Lin, Ranjith Papareddy, Michael Nodine, Alex S Flynt, Jiayu Wen, Eric C Lai

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Identification and analysis of individuals who deviate from their genetically-predicted phenotype. by Gareth Hawkes, Loic Yengo, Sailaja Vedantam, Eirini Marouli, Robin N Beaumont, GIANT Consortium, Jessica Tyrrell, Michael N Weedon, Joel Hirschhorn, Timothy M Frayling, Andrew R Wood

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The RNA-dependent association of phosphatidylinositol 4,5-bisphosphate with intrinsically disordered proteins contribute to nuclear compartmentalization. by Martin Sztacho, Jakub Červenka, Barbora Šalovská, Ludovica Antiga, Peter Hoboth, Pavel Hozák

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Genome scans of facial features in East Africans and cross-population comparisons reveal novel associations. by Chenxing Liu, Myoung Keun Lee, Sahin Naqvi, Hanne Hoskens, Dongjing Liu, Julie D White, Karlijne Indencleef, Harold Matthews, Ryan J Eller, Jiarui Li, Jaaved Mohammed, Tomek Swigut, Stephen Richmond, Mange Manyama, Benedikt Hallgrímsson, Richard A Spritz, Eleanor Feingold, Mary L Marazita, Joanna Wysocka, Susan Walsh, Mark D Shriver, Peter Claes, Seth M Weinberg, John R Shaffer

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Decreased Hsp90 activity protects against TDP-43 neurotoxicity in a C. elegans model of amyotrophic lateral sclerosis. by Laura Garcia-Toscano, Heather N Currey, Joshua C Hincks, Jade G Stair, Nicolas J Lehrbach, Nicole F Liachko

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Bacterial communities of diverse Drosophila species: ecological context of a host-microbe model system. by James Angus Chandler, Jenna Morgan Lang, Srijak Bhatnagar, Jonathan A Eisen, Artyom Kopp

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Genome-wide association studies identify two novel BMP15 mutations responsible for an atypical hyperprolificacy phenotype in sheep. by Julie Demars, Stéphane Fabre, Julien Sarry, Raffaella Rossetti, Hélène Gilbert, Luca Persani, Gwenola Tosser-Klopp, Philippe Mulsant, Zuzanna Nowak, Wioleta Drobik, Elzbieta Martyniuk, Loys Bodin

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The dependence of shugoshin on Bub1-kinase activity is dispensable for the maintenance of spindle assembly checkpoint response in Cryptococcus neoformans. by Satya Dev Polisetty, Krishna Bhat, Kuladeep Das, Ivan Clark, Kevin G Hardwick, Kaustuv Sanyal

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Comparative genomics of large mitochondria in placozoans. by Ana Y Signorovitch, Leo W Buss, Stephen L Dellaporta

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ADELLE: A global testing method for trans-eQTL mapping. by Takintayo Akinbiyi, Mary Sara McPeek, Mark Abney

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Polyploids broadly generate novel haplotypes from trans-specific variation in Arabidopsis arenosa and Arabidopsis lyrata. by Magdalena Bohutínská, Eliška Petříková, Tom R Booker, Cristina Vives Cobo, Jakub Vlček, Gabriela Šrámková, Alžběta Poupětová, Jakub Hojka, Karol Marhold, Levi Yant, Filip Kolář, Roswitha Schmickl

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