Intraneuronal binding of amyloid beta with reelin-Implications for the onset of Alzheimer's disease. by Asgeir Kobro-Flatmoen, Stig W Omholt

“…PLoS Computational Biology…”
Get full text

Orchard: Building large cancer phylogenies using stochastic combinatorial search. by Ethan Kulman, Rui Kuang, Quaid Morris

“…PLoS Computational Biology…”
Get full text

Balancing central control and sensory feedback produces adaptable and robust locomotor patterns in a spiking, neuromechanical model of the salamander spinal cord. by Alessandro Pazzaglia, Andrej Bicanski, Andrea Ferrario, Jonathan Arreguit, Dimitri Ryczko, Auke Ijspeert

“…PLoS Computational Biology…”
Get full text

Adolescent and adult mice use both incremental reinforcement learning and short term memory when learning concurrent stimulus-action associations. by Juliana Chase, Liyu Xia, Lung-Hao Tai, Wan Chen Lin, Anne G E Collins, Linda Wilbrecht

“…PLoS Computational Biology…”
Get full text

A SuperLearner-based pipeline for the development of DNA methylation-derived predictors of phenotypic traits. by Dennis Khodasevich, Nina Holland, Lars van der Laan, Andres Cardenas

“…PLoS Computational Biology…”
Get full text

Human-like face pareidolia emerges in deep neural networks optimized for face and object recognition. by Pranjul Gupta, Katharina Dobs

“…PLoS Computational Biology…”
Get full text

Poly(A)-DG: A deep-learning-based domain generalization method to identify cross-species Poly(A) signal without prior knowledge from target species. by Yumin Zheng, Haohan Wang, Yang Zhang, Xin Gao, Eric P Xing, Min Xu

“…PLoS Computational Biology…”
Get full text

Cancer molecular subtyping using limited multi-omics data with missingness. by Yongqi Bu, Jiaxuan Liang, Zhen Li, Jianbo Wang, Jun Wang, Guoxian Yu

“…PLoS Computational Biology…”
Get full text

Design of field trials for the evaluation of transmissible vaccines in animal populations by Justin K. Sheen, Lee Kennedy-Shaffer, Michael Z. Levy, Charlotte Jessica E. Metcalf

“…PLoS Computational Biology…”
Get full text

Challenging a paradigm: Staggered versus single-pulse mass dog vaccination strategy for rabies elimination. by Brinkley Raynor Bellotti, Elvis W Díaz, Micaela De la Puente-León, Maria T Rieders, Sergio E Recuenco, Michael Z Levy, Ricardo Castillo-Neyra

“…PLoS Computational Biology…”
Get full text

Multicellular model of neuroblastoma proposes unconventional therapy based on multiple roles of p53. by Kenneth Y Wertheim, Robert Chisholm, Paul Richmond, Dawn Walker

“…PLoS Computational Biology…”
Get full text

Mechanisms for dysregulation of excitatory-inhibitory balance underlying allodynia in dorsal horn neural subcircuits. by Alexander G Ginsberg, Scott F Lempka, Bo Duan, Victoria Booth, Jennifer Crodelle

“…PLoS Computational Biology…”
Get full text

Data-driven model discovery and model selection for noisy biological systems. by Xiaojun Wu, MeiLu McDermott, Adam L MacLean

“…PLoS Computational Biology…”
Get full text

Integration of unpaired single cell omics data by deep transfer graph convolutional network. by Yulong Kan, Yunjing Qi, Zhongxiao Zhang, Xikeng Liang, Weihao Wang, Shuilin Jin

“…PLoS Computational Biology…”
Get full text

A data-driven semi-parametric model of SARS-CoV-2 transmission in the United States. by John M Drake, Andreas Handel, Éric Marty, Eamon B O'Dea, Tierney O'Sullivan, Giovanni Righi, Andrew T Tredennick

“…PLoS Computational Biology…”
Get full text

Local field potentials in a pre-motor region predict learned vocal sequences. by Daril E Brown, Jairo I Chavez, Derek H Nguyen, Adam Kadwory, Bradley Voytek, Ezequiel M Arneodo, Timothy Q Gentner, Vikash Gilja

“…PLoS Computational Biology…”
Get full text

Evaluation and comparison of methods for neuronal parameter optimization using the Neuroptimus software framework. by Máté Mohácsi, Márk Patrik Török, Sára Sáray, Luca Tar, Gábor Farkas, Szabolcs Káli

“…PLoS Computational Biology…”
Get full text

Predicting the infecting dengue serotype from antibody titre data using machine learning. by Bethan Cracknell Daniels, Darunee Buddhari, Taweewun Hunsawong, Sopon Iamsirithaworn, Aaron R Farmer, Derek A T Cummings, Kathryn B Anderson, Ilaria Dorigatti

“…PLoS Computational Biology…”
Get full text

DNA spontaneously wrapping around a histone core prefers negative supercoiling: A Brownian dynamics study. by Chunhong Long, Hongqiong Liang, Biao Wan

“…PLoS Computational Biology…”
Get full text

Design of field trials for the evaluation of transmissible vaccines in animal populations. by Justin K Sheen, Lee Kennedy-Shaffer, Michael Z Levy, Charlotte Jessica E Metcalf

“…PLoS Computational Biology…”
Get full text