Bushes in the tree of life. by Antonis Rokas, Sean B Carroll

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Activation of Smurf E3 ligase promoted by smoothened regulates hedgehog signaling through targeting patched turnover. by Shoujun Huang, Zhao Zhang, Chunxia Zhang, Xiangdong Lv, Xiudeng Zheng, Zhenping Chen, Liwei Sun, Hailong Wang, Yuanxiang Zhu, Jing Zhang, Shuyan Yang, Yi Lu, Qinmiao Sun, Yi Tao, Feng Liu, Yun Zhao, Dahua Chen

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Thalamic spindles and Up states coordinate cortical and hippocampal co-ripples in humans. by Charles W Dickey, Ilya A Verzhbinsky, Sophie Kajfez, Burke Q Rosen, Christopher E Gonzalez, Patrick Y Chauvel, Sydney S Cash, Sandipan Pati, Eric Halgren

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Viral and immune dynamics of genital human papillomavirus infections in young women with high temporal resolution. by Nicolas Tessandier, Baptiste Elie, Vanina Boué, Christian Selinger, Massilva Rahmoun, Claire Bernat, Sophie Grasset, Soraya Groc, Anne-Sophie Bedin, Thomas Beneteau, Marine Bonneau, Christelle Graf, Nathalie Jacobs, Tsukushi Kamiya, Marion Kerioui, Julie Lajoie, Imène Melki, Jean-Luc Prétet, Bastien Reyné, Géraldine Schlecht-Louf, Mircea T Sofonea, Olivier Supplisson, Chris Wymant, Vincent Foulongne, Jérémie Guedj, Christophe Hirtz, Marie-Christine Picot, Jacques Reynes, Vincent Tribout, Édouard Tuaillon, Tim Waterboer, Michel Segondy, Ignacio G Bravo, Nathalie Boulle, Carmen Lía Murall, Samuel Alizon

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Environmental fungi target thiol homeostasis to compete with Mycobacterium tuberculosis. by Neha Malhotra, Sangmi Oh, Peter Finin, Jessica Medrano, Jenna Andrews, Michael Goodwin, Tovah E Markowitz, Justin Lack, Helena I M Boshoff, Clifton Earl Barry

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Genetic analysis of pathways regulated by the von Hippel-Lindau tumor suppressor in Caenorhabditis elegans. by Tammie Bishop, Kah Weng Lau, Andrew C R Epstein, Stuart K Kim, Min Jiang, Delia O'Rourke, Christopher W Pugh, Jonathan M Gleadle, Martin S Taylor, Jonathan Hodgkin, Peter J Ratcliffe

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Functional analysis of conserved C. elegans bHLH family members uncovers lifespan control by a peptidergic hub neuron. by G Robert Aguilar, Berta Vidal, Hongzhu Ji, Joke Evenblij, Chien-Po Liao, Hongfei Ji, Giulio Valperga, Christopher Fang-Yen, Oliver Hobert

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Quantitative perturbation-phenotype maps reveal nonlinear responses underlying robustness of PAR-dependent asymmetric cell division. by Nelio T L Rodrigues, Tom Bland, KangBo Ng, Nisha Hirani, Nathan W Goehring

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VANGL2 alleviates inflammatory bowel disease by recruiting the ubiquitin ligase MARCH8 to limit NLRP3 inflammasome activation through OPTN-mediated selective autophagy. by Huaji Jiang, Yingchao Xie, Zhiqiang Hu, Jiansen Lu, Jiahuan Zhang, Hongyu Li, Ke Zeng, Wenqiang Peng, Cheng Yang, Junsheng Huang, Zelong Han, Xiaochun Bai, Xiao Yu

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Viral and immune dynamics of genital human papillomavirus infections in young women with high temporal resolution by Nicolas Tessandier, Baptiste Elie, Vanina Boué, Christian Selinger, Massilva Rahmoun, Claire Bernat, Sophie Grasset, Soraya Groc, Anne-Sophie Bedin, Thomas Beneteau, Marine Bonneau, Christelle Graf, Nathalie Jacobs, Tsukushi Kamiya, Marion Kerioui, Julie Lajoie, Imène Melki, Jean-Luc Prétet, Bastien Reyné, Géraldine Schlecht-Louf, Mircea T. Sofonea, Olivier Supplisson, Chris Wymant, Vincent Foulongne, Jérémie Guedj, Christophe Hirtz, Marie-Christine Picot, Jacques Reynes, Vincent Tribout, Édouard Tuaillon, Tim Waterboer, Michel Segondy, Ignacio G. Bravo, Nathalie Boulle, Carmen Lía Murall, Samuel Alizon

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Ecological drift during colonization drives within-host and between-host heterogeneity in an animal-associated symbiont. by Jason Z Chen, Zeeyong Kwong, Nicole M Gerardo, Nic M Vega

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Hedgehog-regulated ubiquitination controls smoothened trafficking and cell surface expression in Drosophila. by Shuang Li, Yongbin Chen, Qing Shi, Tao Yue, Bing Wang, Jin Jiang

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DNA analysis indicates that Asian elephants are native to Borneo and are therefore a high priority for conservation. by Prithiviraj Fernando, T N C Vidya, John Payne, Michael Stuewe, Geoffrey Davison, Raymond J Alfred, P Andau, Edwin Bosi, Annelisa Kilbourn, Don J Melnick

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A case of convergence: why did a simple alternative to canonical antibodies arise in sharks and camels? by Martin F Flajnik, Nick Deschacht, Serge Muyldermans

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Decreased SynMuv B gene activity in response to viral infection leads to activation of the antiviral RNAi pathway in C. elegans. by Ashwin Seetharaman, Himani Galagali, Elizabeth Linarte, Mona H X Liu, Jennifer D Cohen, Kashish Chetal, Ruslan Sadreyev, Alex J Tate, Taiowa A Montgomery, Gary Ruvkun

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Spontaneous slow cortical potentials and brain oscillations independently influence conscious visual perception. by Lua Koenig, Biyu J He

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Chloramphenicol and gentamicin reduce the evolution of resistance to phage ΦX174 by suppressing a subset of E. coli LPS mutants. by Lavisha Parab, Jordan Romeyer Dherbey, Norma Rivera, Michael Schwarz, Jenna Gallie, Frederic Bertels

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HCNetlas: A reference database of human cell type-specific gene networks to aid disease genetic analyses. by Jiwon Yu, Junha Cha, Geon Koh, Insuk Lee

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Neural correlates of executive control in the avian brain. by Jonas Rose, Michael Colombo

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Recent origin and cultural reversion of a hunter-gatherer group. by Hiroki Oota, Brigitte Pakendorf, Gunter Weiss, Arndt von Haeseler, Surin Pookajorn, Wannapa Settheetham-Ishida, Danai Tiwawech, Takafumi Ishida, Mark Stoneking

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