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141
Development of a Highly Biocompatible Antituberculosis Nanodelivery Formulation Based on Para-Aminosalicylic Acid—Zinc Layered Hydroxide Nanocomposites
Published 2014-01-01“…The in vitro release of PAS from the formulation was found to be sustained in a human body simulated phosphate buffer saline (PBS) solution at pH values of 7.4 and 4.8. Most importantly the nanocomposite prepared using zinc nitrate salt was advantageous in terms of yield and free from toxic zinc oxide contamination and had higher biocompatibility compared to one prepared using a zinc oxide precursor. …”
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142
An Innovative Drug Delivery System Loaded with a Modified Combination of Triple Antibiotics for Use in Endodontic Applications
Published 2020-01-01“…The deposited “PMC-loaded PLGA-coated ceramic microspheres (PPCMs)” were dried and incubated in phosphate buffer saline (PBS) for 21 days. The drug release from PPCMs was quantified by a UV spectrophotometer. …”
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143
MSC-Derived Extracellular Vesicle-Delivered L-PGDS Inhibit Gastric Cancer Progression by Suppressing Cancer Cell Stemness and STAT3 Phosphorylation
Published 2022-01-01“…In vivo, EVs-L-PGDS inhibited the tumor growth in nude mouse subcutaneous tumor-bearing model. Compared with the PBS and EVs containing empty vector (EVs-Vector) group, more apoptotic cells and higher L-PGDS expression were detected in tumor tissue of the EVs-L-PGDS treatment group. …”
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144
Effect of Dayak Onion (Eleutherine bulbosa (Mill.) Urb.) on the Immune Response and Gene Expression of Nile Tilapia (Oreochromis niloticus) Infected with Aeromonas hydrophila
Published 2023-09-01“…Nile tilapia in treatment C+, P5, P10, and P15 were injected with A. hydrophila 10â¶ CFU mLâ»1, while that in treatment C- was injected with phosphate buffered saline (PBS) intramuscularly. The results showed that the dietary with 15% powder and 0.5% crude extract significantly improved the hematology and immune response parameters compared to the control after the challenge against A. hydrophila (P<0.05). …”
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145
Efficacy of aquatic exercises on balance in children with sickle cell anemia: A randomized controlled trial
Published 2023-11-01“…Balance was measured before and after treatment using the Pediatric Balance Scale (PBS). A complete blood analysis was performed before and after treatment. …”
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146
Construction and characterization of bioluminescent Salmonella Reading outbreak and non-outbreak strains
Published 2025-02-01“…The chloramphenicol acetyltransferase gene was cloned into the plasmid pBS-slpGFPluxABCDE, which carries luxABCDE operon and an ampicillin resistance gene. …”
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147
CD40 Ligand Potentiates Immunogenecity of <i>Mycoplasma pneumoniae</i> Subunit Vaccine Candidate in a Murine Model
Published 2025-01-01“…Seppic ISA 201 emulsified protein, conventional Mhp vaccine and PBS control groups were included. Immunogenecity was assessed by specific IgG antibody response, splenic lymphocyte proliferation, and cytokine IL-4 and IFN-γ levels. …”
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148
Antibody Responses and the Vaccine Efficacy of Recombinant Glycosyltransferase and Nicastrin Against <i>Schistosoma japonicum</i>
Published 2025-01-01“…Immunized mice exhibited significantly elevated specific IgG antibody levels after three immunizations compared to adjuvant and PBS controls. Furthermore, immunization with recombinant glycosyltransferase and nicastrin significantly reduced the reproductive capacity of female worms and liver egg burden, though egg hatchability and adult worm survival were unaffected. …”
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149
Polielektrolitlerin Molekül Ağırlığı ve Harman Oranının Çok Tabakalı Filmlerin Gelişimine Etkisinin ve İlaç Adsorpsiyon/Desorpsiyon Uygulamalarında Kullanımlarının QCM-D Tekniğiyle...
Published 2024-03-01“…Hazırlanan LbL saf/harman yapılı fonksiyonel filmlerde ibuprofen sodyum ilacı için yükleme ve salım çalışmaları QCM-D tekniği ve UV-Vis analizleriyle nötral (pH:6,8), asidik (pH:2) ve bazik (pH:11) fosfat tampon çözeltisinde (PBS) gerçekleştirilmiştir. Çalışmada, ilaç salım sistemleri için yenilikçi, ekonomik ve pratik bir yaklaşımın sunulmasının yanı sıra; LbL kaplama koşullarına bağlı olarak (i) morfolojisi ve kompozisyonu kontrol edilebilen, (ii) ilaç yükleme ve salım özellikleri ayarlanabilen ve geniş bir pH (pH:2-11) aralığında ilaç salımı yapabilen sistemler geliştirilmiştir. …”
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150
Network Pharmacology and Experimental Validation of the Therapeutic Effect of Baji Capsule on LPS-Induced Osteoporosis
Published 2025-02-01“…Mice were treated with vitamin E (100mg/kg), PBS, high-dose Baji capsule (810mg/kg) and low-dose Baji capsule (90mg/kg), respectively. …”
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151
Oral Immunisation With Non‐GMO Surface Displayed SARS‐CoV‐2 Spike Epitopes on Bacteria‐Like Particles Provokes Robust Humoral and Cellular Immune Responses, and Modulated the Gut M...
Published 2025-01-01“…Twenty‐eight 6‐week‐old male C57BL/6 mice were orally immunised with the following: PBS (control), Lm. fermentum‐derived BLPs only, BLPs displaying SARS‐CoV‐2 spike S1‐2, or BLPs displaying SARS‐CoV‐2 spike S1‐3 epitopes. …”
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152
Pathogen delivery route impacts disease severity in experimental Mycoplasma ovipneumoniae infection of domestic lambs
Published 2025-01-01“…Lambs were inoculated with PBS (control) or with ceftiofur-treated nasal wash fluid obtained from sheep with natural M. ovipneumoniae infection, monitored for eight weeks, and subsequently euthanized. …”
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153
Effect of trans-cinnamaldehyde and peracetic acid alone or in combination on multidrug-resistant Salmonella Heidelberg on broiler drumsticks under scalding alone or with chilling a...
Published 2025-03-01“…After scalding, the drumsticks were rinsed in 350 mL phosphate-buffered saline (PBS) for 30 s to obtain surviving S. Heidelberg populations enumerated by surface plating and enrichment methods. …”
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154
Neurotrophic Effect of Adipose Tissue-Derived Stem Cells on Erectile Function Recovery by Pigment Epithelium-Derived Factor Secretion in a Rat Model of Cavernous Nerve Injury
Published 2016-01-01“…On day 28 after the intracavernous injection, the ADSCs group exhibited a significantly increased ICP compared with the phosphate buffered saline- (PBS-) treated group. Moreover, the neuronal nitric oxide synthase (nNOS) and S100 expression in penile dorsal nerves and the smooth muscle content to collagen ratio in penile tissues significantly increased. …”
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155
Vaccination of mice with Trichinella spiralis C-type lectin elicited the protective immunity and enhanced gut epithelial barrier function.
Published 2025-01-01“…At one week after challenge, the numbers of goblet cells and expression level of Muc2, Muc5ac and pro-inflammatory cytokines (TNF-α and IL-1β) in gut tissues of vaccinated mice were obviously decreased, while expression of anti-inflammatory cytokines (IL-4 and IL-10) was evidently increased, compared to the infected PBS group. It is interesting that expression levels of gut epithelial tight junctions (TJs; occludin, claudin-1 and E-cad) were prominently elevated and intestinal permeability was interestingly declined in vaccinated mice. …”
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156
Pirfenidone Alleviates Choroidal Neovascular Fibrosis through TGF-β/Smad Signaling Pathway
Published 2021-01-01“…C57BL/6J male mice (aged from 6 to 8 weeks) received intravitreal injections of phosphate-buffered saline (PBS)/PFD solution on 14 days after laser injury. …”
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157
Radiocobalt-Labeling of a Polypyridylamine Chelate Conjugated to GE11 for EGFR-Targeted Theranostics
Published 2025-01-01“…[<sup>57</sup>Co]Co-TZTPEN-GE11 showed high stability in PBS (pH 5) and specific uptake in EGFR-positive cell lines. …”
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158
Preparation and In Vivo Expression of CS-PEI/pCGRP Complex for Promoting Fracture Healing
Published 2019-01-01“…A rat femoral fracture model was established and treated with PBS, pCGRP, CS-PEI, and CS-PEI/pCGRP to detect the expression of CGRP and downstream genes in early healing of fractures by RT-qPCR, western blot, and immunohistochemistry (IHC). …”
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159
Human Umbilical Cord Mesenchymal Stem Cells Attenuate Ocular Hypertension-Induced Retinal Neuroinflammation via Toll-Like Receptor 4 Pathway
Published 2019-01-01“…The animals were randomly divided into three groups: the normal group, the OHT+phosphate-buffered saline (PBS) group, and the OHT+hUC-MSC group. Retinal morphology was evaluated by measuring the inner retinal thickness via optical coherence tomography (OCT). …”
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160
The transcriptome of MHV‐infected RAW264.7 cells offers an alternative model for macrophage innate immunity research
Published 2025-01-01“….), the attached cells were washed with PBS and harvested in Trizol reagent. Then The harvest is subjected to transcriptome sequencing. …”
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