Evolution of Self-reported Neuropsychiatric Symptoms After Switching from Dolutegravir/Abacavir/Lamivudine to Bictegravir/Emtricitabine/Tenofovir Alafenamide: Results from the Rand... by Barbara Rossetti, Micol Ferrara, Lucia Taramasso, Francesca Bai, Francesca Lombardi, Nicoletta Ciccarelli, Miriam Durante, Francesca Alladio, Federica Bonazza, Ilaria Rancan, Francesca Montagnani, Antonio Di Biagio, Antonella d’Arminio Monforte, Maurizio Zazzi, Massimiliano Fabbiani, for DOBINeuro study group

“…The original sample size was 50 PLWH per arm, but the enrollment was prematurely stopped due to a delayed recruitment process. …”
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Supplementation with essential amino acids in the early stage of carbohydrate reintroduction after a very-low energy ketogenic therapy (VLEKT) improves body cell mass, muscle stren... by Giuseppe Annunziata, Ludovica Verde, Vincenzo D’Orsi, Massimiliano Caprio, Stefania Gorini, Silvia Savastano, Annamaria Colao, Giovanna Muscogiuri, Luigi Barrea

“…For this reason, the present study aimed to evaluate the effects of supplementation with 8 g per day of essential amino acids (EAAs) on these parameters. …”
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Exploring the epidemiological impact of attractive targeted sugar bait against malaria in combination with standard malaria control by Nima R. Moghaddas, Mohamed M. Traore, Gunter C. Müller, Joseph Wagman, Javan Chanda, Julian Entwistle, Christen M. Fornadel, Thomas S. Churcher

“…For example, observing a dyed fraction of 5% would indicate a daily bait-feeding rate of 0.024 (range 0.008–0.049) which is projected to result in 0.13 clinical cases averted per person-year (range 0.051–0.22), a 39% efficacy (range 12–66%) in this particular site. …”
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The Impact of Hangeshashinto on Symptoms and Gut Microbiota in Diarrhea-type Irritable Bowel Syndrome: A Retrospective Analysis by Naohisa Yoshida, Takeshi Yasuda, Yoshikazu Inagaki, Daisuke Hasegawa, Kohei Fukumoto, Takaaki Murakami, Ryohei Hirose, Osamu Dohi, Kazuhiko Uchiyama, Tomohisa Takagi, Yoshito Itoh

“…The improvement rates of stool frequency, stool consistency, and abdominal pain were 59.0%, 51.0%, and 62.0%, respectively. The stool frequency per week before and after HST was 21.7±18.2 vs. 14.0±12.6 (p<0.001). …”
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Association between neutrophil-to-eosinophil ratio and efficacy outcomes with avelumab plus axitinib or sunitinib in patients with advanced renal cell carcinoma: post hoc analyses... by Brian Rini, Mariangela Mariani, Alessandra di Pietro, Paul Nathan, Christian Kollmannsberger, Marc-Oliver Grimm, Martin H Voss, Bradley A McGregor, Mehmet A Bilen, Yoshihiko Tomita, Bo Huang, Robert Amezquita, Matthew Tucker, Yu-Wei Chen

“…Objective We report post hoc analyses of efficacy with first-line avelumab plus axitinib or sunitinib according to baseline neutrophil-to-eosinophil ratio (NER) in patients with advanced renal cell carcinoma (aRCC) from the JAVELIN Renal 101 phase 3 trial.Methods and analysis Progression-free survival (PFS), overall survival (OS) and objective response per baseline NER were analysed in the overall population and in patients with programmed death ligand 1 (PD-L1+) tumours. …”
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Combination of Compound Kushen injection with first-line treatment versus first-line treatment alone for advanced colorectal cancer: a study protocol for a multicenter, openlabel,... by Jingyuan Wu, Yuansha Ge, Guanghui Zhu, Ruike Gao, Xiaoyu Zhu, Ying Zhang, Jie Li

“…Both groups will receive at least 4 cycles of first-line therapy (FOLFOX/FOLFIRI/CAPEOX ± cetuximab/bevacizumab) in 14–21 day cycles, and the experimental group will receive additional CKI with a cumulative dose of 200 ml per cycle. Patients who achieve a complete response, partial response, or stable disease after 4–6 months will receive maintenance therapy until disease progression or another endpoint event, such as toxicity or death, occurs.. …”
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Comprehensive Assessment of Rapeseed Meal as a Fish Meal Substitute in Hybrid Sturgeon (Acipenser schrenckii ♀ × Acipenser baerii ♂) Diets: Impacts on Growth Performance, Body Comp... by Wenpeng Zhang, Siyuan Liu, Shidi Wang, Huamin Wang, Kaibo Ge, Yuhong Yang, Shaoxia Lu, Shicheng Han, Haibo Jiang, Chang’an Wang, Hongbai Liu

“…A total of 450 juvenile hybrid sturgeon with similar weights were randomly assigned to five dietary groups, each with triplicates of 30 fish per tank. For 12 weeks, FM was replaced with varying percentages of RM (0%, 25%, 50%, 75%, and 100%). …”
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Image-based anomaly detection in low-light industrial environments with feature enhancement by Dinh-Cuong Hoang, Phan Xuan Tan, Anh-Nhat Nguyen, Son-Anh Bui, Ta Huu Anh Duong, Tuan-Minh Huynh, Duc-Manh Nguyen, Viet-Anh Trinh, Quang-Huy Ha, Nguyen Dinh Bao Long, Duc-Thanh Tran, Xuan-Tung Dinh, Van-Hiep Duong, Tran Thi Thuy Trang

“…Additionally, the framework maintains a real-time inference speed of 60 frames per second (FPS), making it well-suited for deployment in industrial settings. …”
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Prevalence of Computer Vision Syndrome and Associated Factors among Instructors in Ethiopian Universities: A Web-Based Cross-Sectional Study by Demisu Zenbaba, Biniyam Sahiledengle, Mitiku Bonsa, Yohannes Tekalegn, Jember Azanaw, Vijay Kumar Chattu

“…A constant use of computer for 3 hours and more per day can cause computer vision syndrome (CVS), which is one of the leading occupational hazards of the 21st century. …”
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Development of a Flexible Produce Supply Chain Food Safety Risk Model: Comparing Tradeoffs Between Improved Process Controls and Additional Product Testing for Leafy Greens as a Te... by Gabriella Pinto, Gustavo A. Reyes, Cecil Barnett-Neefs, YeonJin Jung, Chenhao Qian, Martin Wiedmann, Matthew J. Stasiewicz

“…A leafy green supply chain contaminated with Shiga-toxin-producing Escherichia coli was modeled with a mean of 1 pathogen cell per pound (µ = 1 CFU/lb or −2.65 Log(CFU/g)) under high (σ = 0.8 Log(CFU/g)) and low (σ = 0.2 Log(CFU/g)) variability. …”
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Geographic factors associated with SARS-CoV-2 prevalence during the first wave − 6 districts in Zambia, July 2020 by Stephen Longa Chanda, Tadatsugu Imamura, Warren Malambo, Rommel Bain, Chisenga Musuka, Nyambe Sinyange, Jonas Z. Hines

“…Results Overall, the median SARS-CoV-2 prevalence in the 96 SEAs was 41.7 (Interquartile range (IQR), 0.0-96.2) infections per 1000 persons. In the multivariable CAR analysis, increasing SES vulnerability was associated with lower SARS-CoV-2 prevalence (aPR) = 0.85, 95% CI: 0.78–0.94). …”
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Charm fragmentation fractions and $$\mathbf {c\overline{c}}$$ c c ¯ cross section in p–Pb collisions at $$\mathbf {\sqrt{s _{NN}}=5.02 TeV}$$ s NN = 5.02 TeV by ALICE Collaboration

“…Abstract The total charm-quark production cross section per unit of rapidity $$\textrm{d}\sigma ({{\textrm{c}}\overline{\textrm{c}}})/\textrm{d}y$$ d σ ( c c ¯ ) / d y , and the fragmentation fractions of charm quarks to different charm-hadron species $$f(\textrm{c}\rightarrow {\textrm{h}}_{\textrm{c}})$$ f ( c → h c ) , are measured for the first time in p–Pb collisions at $$\sqrt{s_\textrm{NN}} = 5.02~\text {Te}\hspace{-1.00006pt}\textrm{V} $$ s NN = 5.02 Te V at midrapidity ( $$-0.96<y<0.04$$ - 0.96 < y < 0.04 in the centre-of-mass frame) using data collected by ALICE at the CERN LHC. …”
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Oversized cells activate global proteasome-mediated protein degradation to maintain cell size homeostasis by Shixuan Liu, Ceryl Tan, Chloe Melo-Gavin, Miriam B Ginzberg, Ron Blutrich, Nish Patel, Michael Rape, Kevin G Mark, Ran Kafri

“…In contrast, oversized cells that undergo compensatory growth slowdown exhibit a superlinear increase in proteasome-mediated protein degradation, with accelerated protein turnover per unit mass, suggesting activation of the proteasomal degradation pathway. …”
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Detection and characterization of multidrug resistant Escherichia coli carrying virulence gene isolated from broilers in Bangladesh by Md. Sirazul Islam, Chandan Nath, F. M. Yasir Hasib, Tahia Ahmed Logno, Md. Helal Uddin, Mohammad Mahmudul Hassan, Sharmin Chowdhury

“…Each pooled sample comprised randomly selected cloacal swabs from five birds per farm. E. coli isolates were identified using standard bacteriological approach, followed by biochemical assays and PCR. …”
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Assessing the effect of On-site supportive communication training (On-site SCT) on doctor burnout: a randomized controlled trial by K.K. Antonsen, J.D. Lyhne, A.T. Johnsen, S. Eßer-Naumann, L.Ø. Poulsen, L. Lund, S. Timm, L.H. Jensen

“…Doctors were eligible if they worked in the outpatient clinic at least four days per month and provided informed consent. Doctors in the intervention group underwent a two-hour introduction followed by three full days of On-site SCT facilitated by in-house psychologists, while those in the control group continued standard practices. …”
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A Prospective, Randomized Comparison of Duodenoscope Reprocessing Surveillance Methods by Travis J. De Wolfe, Nasia Safdar, Megan Meller, John Marx, Patrick R. Pfau, Eric M. Nelsen, Mark E. Benson, Anurag Soni, Mark Reichelderfer, Megan Duster, Deepak V. Gopal

“…Mean processing time (27.35 and 5.11 minutes, p<0.001) and total cost per sample event ($17.87 and $15.04) were lower using the UWHC method. …”
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Application of photodynamic therapy with 5-aminolevulinic acid and fractional CO2 laser for the management of recalcitrant plantar warts by Jiaoquan Chen, Xinyi Xie, Yingxue Liu, Fengyi Chen, Yeqing Gong, Bihua Liang, Yiling Wu, Shiqi He, Yueming Li, Huilan Zhu, Shaoyin Ma

“…In total, 40 lesions were treated across 1 to 9 PDT sessions, with an average of 5.2 ± 2.86 sessions per patient. Complete clearance was achieved in 3 patients (30 %), 4 patients (40 %) showed an excellent response (≥80 % improvement), while 2 patients had a partial response. …”
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Impact of Novel Guidelines on Multifactorial Control and Its Association with Mortality in Adult Patients with Hypertension and Newly Diagnosed Type 2 Diabetes: A 4-Year Prospectiv... by Ngoc-Thanh-Van Nguyen, Hoa Ngoc Chau, Nam Hoai Le, Hai Hoang Nguyen, Hoai-An Nguyen

“…During follow-up, the mortality rate was 24.4 events per 1000 patient-years, exclusively in patients with early newly diagnosed diabetes. …”
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Optimasi Formula Produk Mi Basah Terfortifikasi Bubuk Spirulina Platensis L. Menggunakan D-Optimal Mixture Design by Hendrix Yulis Setyawan, Eka Wahyu Belianna, Lana Izzatul Afifal, Devi Dwi Damayanti, Dhea Aura Bening Shafira, Karlina Wijayanti

“…Keywords: Proximate Analysis; Design Expert 13 Version; Wet Noodles; Spirulina platensis Abstrak Kehidupan produktif masyarakat Indonesia mendorong konsumsi mi instan yang murah dan praktis, dengan 3,8% mengonsumsinya lebih dari sekali per hari. Namun, kandungan protein mi instan yang rendah memerlukan fortifikasi, salah satunya dengan bubuk Spirulina platensisyang mengandung protein tinggi hingga 71,90%. …”
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Accounting for observation biases associated with counts of young when estimating fecundity: case study on the arboreal-nesting red kite (Milvus milvus) by Sollmann, Rahel, Adenot, Nathalie, Spakovszky, Peter, Windt, Jendrik, Mattsson, Brady J.

“…These counts can, however, suffer from over and undercounting, which can lead to biased estimates of fecundity (average number of nestlings per brood). Statistical model development to account for observation bias has focused on false negatives (undercounts), yet it has been shown that these models are sensitive to the presence of false positives (overcounts) when they are not accounted for. …”
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