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  1. 9281
  2. 9282

    Interdependence of coagulation with immunotherapy and BRAF/MEK inhibitor therapy: results from a prospective study by Malte Beckmann, Julian Schlüter, Michael Erdmann, Rafaela Kramer, Sarah Cunningham, Holger Hackstein, Robert Zimmermann, Lucie Heinzerling

    Published 2024-11-01
    “…With cancer patients having a higher risk of thrombotic events per se, it is crucial to dissect and characterize the mechanisms that cause pro-coagulative effects induced by systemic tumor therapies and their potential interplay with anti-tumor response. …”
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  3. 9283

    Comparative evaluation of non-contrast MRI versus gadoxetic acid-enhanced abbreviated protocols in detecting colorectal liver metastases by Haoran Dai, Cheng Yan, Xi Jia, Yuyao Xiao, Xinyue Liang, Chun Yang, Kai Liu, Mengsu Zeng

    Published 2025-01-01
    “…Two independent readers assessed three MRI protocols per patient: Protocol 1 included non-contrast sequences (T2-weighted turbo spin-echo, T1-weighted Dixon, diffusion-weighted imaging (DWI), and ADC mapping). …”
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  4. 9284
  5. 9285

    Bio-ecological characteristics of Malus genus species in the context of prospective directions in horticulture and landscape forestry by Tetiana Moskalets, Oleksandr Kratiuk, Mariana Ivankiv, Sergii Shevchenko, Nataliia Shevchuk

    Published 2024-12-01
    “…Among these, crab apple varieties, particularly the European wild apple and the plumleaved apple, were identified as having the highest average number of seeds per fruit – 10 and 8 seeds, respectively. It was also shown that the seeds of the wild apple are relatively large, with the 100-seed weight exceeding 3.9 g. …”
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  6. 9286

    Causal associations of ambient particulate matter 10 and Alzheimer’s disease: result from a two-sample multivariable Mendelian randomization study by Zehan Huang, Guodong He, Shuo Sun, Yingqing Feng, Yuqing Huang

    Published 2024-10-01
    “…In the univariate MR, pooled meta-analysis of genetically predicted PM10 was associated with a 99% increased risk of AD (95% CI: 1.25, 3.15, p = 0.004) per 1 standard deviation (SD) increment of PM10 by IVW, and in the multivariable MR with pooled meta-analysis, we found that each SD increase in PM10 was associated with a 127% increase in the risk of AD (95% CI: 1.33, 3.86, p = 0.002) after accounting for education levels. …”
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  7. 9287
  8. 9288

    The Dose-Dependent Effects of Spironolactone on TGF-β1 Expression and the Vulnerability to Atrial Fibrillation in Spontaneously Hypertensive Rats by Mirong Tang, Yan Chen, Fuqing Sun, Liangliang Yan

    Published 2021-01-01
    “…Forty 20-week-old male SHRs were randomly divided into 4 groups (10 rats per group): 3 spironolactone groups were lower-dose group (10 mg·kg−1·d−1, dissolved in 2 ml saline solution, group SL), medium-dose group (40 mg·kg−1·d−1, dissolved in 2 ml saline solution, group SM), higher-dose group (80 mg·kg−1·d−1, dissolved in 2 ml saline solution, group SH) and one hypertension group (2 ml saline solution for stomach gavage, group H). …”
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  9. 9289

    Modulation of Acid Sphingomyelinase in Melanoma Reprogrammes the Tumour Immune Microenvironment by Emma Assi, Davide Cervia, Laura Bizzozero, Annalisa Capobianco, Sarah Pambianco, Federica Morisi, Clara De Palma, Claudia Moscheni, Paolo Pellegrino, Emilio Clementi, Cristiana Perrotta

    Published 2015-01-01
    “…This study demonstrates that change of A-SMase expression in cancer cells is sufficient per se to tune in vivo melanoma growth and that A-SMase levels modulate immune cells at tumour site. …”
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  10. 9290

    Sustainability index analysis of microalgae cultivated in biorefinery palm oil mill effluent by A. Santoso, T. Handayani, D. Pinardi, K. Kusrestuwardani, N. Widyastuti, I. Djarot, J. Haryanti, A. Sitomurni, H. Apriyanto

    Published 2023-07-01
    “…Some leverage attributes that require more attention in order to improve sustainability are management experience and skills (in environment dimension), involvement of family member (in the social dimension), the productivity level (in economic dimension), and management of experience and skill (technological dimention).CONCLUSION: Based on the prospective analysis, it is known that there are 4 key factors or dominant factors that are very influential in the microalgae supply system, namely production, productivity, land conversion, consumption per capita and population. It is still necessary to do further research for the utilization of microalgae biomass into value-added products with an optimal, technically, economically, environmentally and socially sustainable system. …”
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  11. 9291

    Effects of traditional Chinese medicine massage therapy on pain, functional activity, muscle activation patterns and proprioception in knee osteoarthritis: a randomised controlled... by Xin Zhou, Cheng Tang, Bowen Zhu, Yangyang Fu, Min Fang, Sitong Fang, Qingguang Zhu, Yuen Yee Janice Hiew

    Published 2024-12-01
    “…Outcome analyses will be conducted on both intention-to-treat and per-protocol populations. A preliminary analysis will test whether TCM massage, in addition to exercise, has statistically better outcomes.Ethics and dissemination The study protocol has received approval from the Ethics Committee of Shuguang Hospital, Shanghai University of Traditional Chinese Medicine (2023-1357-124-01).All study participants will be required to give written informed consent. …”
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  12. 9292

    Effect of daily alcohol intake on sex hormone levels among postmenopausal breast cancer survivors on aromatase inhibitor therapy: a randomized controlled crossover pilot study by Elizabeth Mostofsky, Julie E. Buring, Steven E. Come, Nadine M. Tung, Cancan Zhang, Kenneth J. Mukamal

    Published 2025-01-01
    “…Whether consuming alcohol within the recommended limit of one serving per day increases sex hormone levels among postmenopausal women taking aromatase inhibitors (AI) to inhibit estrogen production remains unknown. …”
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  13. 9293

    A Study on the Dietary Yeast Polysaccharide Supplementation in Growth Performance, Antioxidant Capacity, and Immunity of Juvenile Largemouth Bass (<i>Micropterus salmoides</i>) by Junjie Qin, Haifeng Mi, Mingchun Ren, Dongyu Huang, Hualiang Liang, Lu Zhang, Tao Teng, Heng Yin

    Published 2025-01-01
    “…A total of 300 healthy fish (3.20 ± 0.03 g) were randomly divided into 15 floating cages (1 × 1 × 1 m) in five different groups, with three replicates per group, for an 8-week culture experiment. The 0.10Y and 0.20Y groups had significantly higher feed conversion ratios compared with the control group. …”
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  14. 9294

    Efficacy of personalized feedback in encouraging sustainable washing behavior: evidence from a pilot study in Germany by Laura Höpfl, Laura Höpfl, Laura Höpfl, Ivan Đula, Ivan Đula, Ivan Đula, Francisco Kiss, Rebecca Walter, Maria Wirzberger, Maria Wirzberger, Maria Wirzberger

    Published 2025-01-01
    “…The within-subjects design included (1) a baseline condition, (2) feedback on energy consumption (kWh), and (3) feedback on monetary costs per cycle (EUR). Data collection encompassed pre- and post-condition surveys, a final comprehensive survey, and a diary-formatted table. …”
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  15. 9295

    Investigating the impact of oligo-chitosan on the growth dynamics and yield traits of Oryza sativa L. ‘BRRI dhan29’ under subtropical conditions by Afrina Rahman, Rayhan Ahammed, Jayanta Roy, Md Liton Mia, Mohammad Abdul Kader, Mubarak A. Khan, Md Harun Rashid, Uttam Kumer Sarker, Md Romij Uddin, Md Shafiqul Islam

    Published 2025-01-01
    “…Overall, our findings suggest that additional foliar spray of chitosan with previously recommended cultivation practice can increase the yield per unit area and offers promising technology to achieve potential yield in farmer's field.…”
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  16. 9296

    The effects of the urotensin-II receptor antagonist palosuran treatment on the corpora cavernosa of streptozotocin-induced diabetic rats by Murat Olukman, Cenk Can, Sibel Ülker, Yiğit Uyanikgil, Türker Çavuşoğlu, Neslihan Düzenli, Deniz Coşkunsever, Fatma G. Kozcu

    Published 2025-01-01
    “…Methods: Streptozotocin-induced diabetic rats were treated with palosuran 300 mg/kg per day for 6 weeks. Contraction of CC induced by potassium chloride, phenylephrine, and NG-nitro-L-arginine methyl ester and relaxation of CC induced by electrical field stimulation (EFS) and sodium nitroprusside (SNP) (endothelium-dependent and endothelium-independent stimuli, respectively), and Y-27632 (Rho-kinase inhibitor) were examined in organ baths. …”
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  17. 9297

    Periodontitis and systemic inflammation as independent and interacting risk factors for mortality: evidence from a prospective cohort study by Christiane Pink, Birte Holtfreter, Henry Völzke, Matthias Nauck, Marcus Dörr, Thomas Kocher

    Published 2023-11-01
    “…All markers of periodontitis and inflammation showed apparent associations with all-cause mortality (HRs per SD-increase: mean PPD: 1.068 (95% confidence interval (CI): 0.988–1.155), mean CAL: 1.205 (95% CI: 1.097–1.323), missing teeth: 1.180 (95% CI: 1.065–1.307), periodontitis score: 1.394 (95% CI: 1.202–1.616), leukocytes: 1.264 (95% CI: 1.163–1.374), fibrinogen: 1.120 (95% CI: 1.030–1.218), CRP: 1.231 (95% CI: 1.109–1.366), inflammation score: 1.358 (95% CI: 1.210–1.523)). …”
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  18. 9298

    SpecPCM: A Low-Power PCM-Based In-Memory Computing Accelerator for Full-Stack Mass Spectrometry Analysis by Keming Fan, Ashkan Moradifirouzabadi, Xiangjin Wu, Zheyu Li, Flavio Ponzina, Anton Persson, Eric Pop, Tajana Rosing, Mingu Kang

    Published 2024-01-01
    “…SpecPCM, with up to three bits per cell, achieves speedups of up to <inline-formula> <tex-math notation="LaTeX">$82\times $ </tex-math></inline-formula> and <inline-formula> <tex-math notation="LaTeX">$143\times $ </tex-math></inline-formula> for MS clustering and DB search tasks, respectively, along with a four-orders-of-magnitude improvement in energy efficiency compared with state-of-the-art (SoA) CPU/GPU tools.…”
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  19. 9299

    Economic impact of heart failure with preserved ejection fraction: insights from the ALDO‐DHF trial by Djawid Hashemi, Ludwig Dettmann, Tobias D. Trippel, Volker Holzendorf, Johannes Petutschnigg, Rolf Wachter, Gerd Hasenfuß, Burkert Pieske, Antonia Zapf, Frank Edelmann

    Published 2020-06-01
    “…The average annual costs per patient in this cohort came up to €1, 118 (±2,475), and the median costs were €332. …”
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  20. 9300

    The kinetics of maternal and self-developed Streptococcus suis-specific antibodies by Sandra Vreman, Rutger Jansen, Mikael Bastian, Patricia Beckers, Miriam van Riet, Helmi Fijten, Jan Fledderus, Astrid de Greeff, Hélène Winkelman, Norbert Stockhofe-Zurwieden, Lluís Fabà, Henk J. Wisselink, Manouk Vrieling

    Published 2025-02-01
    “…Subsequently, study II used one of these farms to evaluate S. suis-specific and total antibody kinetics in piglets (10 litters with 6 selected piglets per litter, total n = 60) from birth until 10 weeks of age. …”
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