Cost-Benefit Analysis of Genetic Testing as a Prenatal Diagnostic Tool for Thalassemia: A Single-Center Study From Central Thailand by Malasai K, Jittikoon J, Udomsinprasert W, Talungchit P, Youngkong S, Sangroongruangsri S, Mahasirimongkol S, Chaikledkaew U

“…Both one-way and probabilistic sensitivity analyses were conducted to account for uncertainties in the parameters used.Results: The results revealed that adhering to the standard screening program with genetic testing resulted in a cost-savings of approximately 490 USD per prevented thalassemia case. Among the diagnostic methods, the specificity of the MCV/MCH with DCIP showed a higher degree of sensitivity relative to other testing methods, significantly influencing the outcomes. …”
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Homologous recombination deficiency test validation in patients with high-grade advanced ovarian cancer by Angelica Nogueira Rodrigues, Andreza Karine de Barros Almeida Souto, Diocésio Alves Pinto de Andrade, Larissa Müller Gomes, Sandra Satie Koide, Renata de Godoy e Silva, Bruno Batista de Souza, Juliana Doblas Massaro, Andréia Cristina de Melo, Andrea Morais Borges, Camila Giro, Carlos Augusto Vasconcelos de Andrade, Cesar Martins da Costa, Daniel Luiz Gimenes, Eduardo Caminha Bandeira de Mello, Fernanda Cesar de Oliveira, Frederico Müller de Toledo Lima, Gabriel Lima Lopes, Gustavo de Oliveira Bretas, Gustavo Guerra Jacob, Herika Lucia da Costa Silva, Juliana Ferrari Notaro, Lara Ladislau Alves, Marcos Veloso Moitinho, Mirian Cristina da Silva, Roberto Abramoff, Thais Amaral da Cunha Rauber, Rodrigo Dienstmann, Fernanda Christtanini Koyama

“…Our in-house assay is eligible for diagnostic test approval and market access as per Brazilian regulations.…”
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Effect of Extrusion on the Functional Properties and Bioactive Compounds of Tamarind (Tamarindus indica L.) Shell by Dalia Samanta Aguilar-Avila, Hector Eduardo Martinez-Flores, Eduardo Morales-Sanchez, Rosalía Reynoso-Camacho, Ma. Guadalupe Garnica-Romo

“…The dry powdered tamarind shell was conditioned to have 32 or 39 g of water per 100 g of shell, prior to being subjected to extrusion. …”
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Isolation of competent actinomycetes strains from soil planted with three species of mint irrigated with olive mill wastewater by Oumaima Beroigui, Lahsen El Ghadraoui, Faouzi Errachidi

“…The application of 5 L of OMWW per m² is optimal for maximum hydrolytic enzyme production by actinomycetes. …”
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Green analysis of illicit drugs on banknote dust by Teresa Cecchi, Arianna Giuliani, Carlo Catini

“…Its concentration ranged only one order of magnitude, from 2.76E+02 to 4.01E+03 mg of cocaine per gram of banknote dust, in agreement with previous results obtained with methanol as an extractant and organic modifier. …”
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How does the concentration of spatial allocation of urban construction land across cities affect carbon emission intensity in China? by Hui Yang, Cheng Chen, Jingye Li, Min Li, Stefan Sieber, Kaisheng Long

“…The geographical extent of this effect depends on the geographical distance between cities and their gross domestic product per capita. These findings provide reference values for the spatial allocation and scale control of UCL, and carbon reduction in countries whose UCL allocation and land planning are primarily controlled by the government.…”
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Liraglutide alleviates high-fat diet-induced kidney injury in mice by regulating the CaMKKβ/AMPK pathway by Yingli Xuan, Ting-ting Ding, Xiao-lei Mao, Shiqing Pang, Ruibin He, Li Qin, Jiang zi Yuan

“…Therefore, this study was designed to observe the characteristics and potential mechanism of liraglutide against obesity-related kidney disease.Methods Thirty-six C57BL/6J male mice were randomly divided into six groups (n = 6 per group). Obesity-related nephropathy was induced in mice by continuous feeding of high-fat diet (HFD) for 12 weeks. …”
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Item-level measurement properties of the pediatric awareness and sensory motor assessment in children with medical complexity by Brooke Mulrenin, Bryant A. Seamon, Carrie Cormack, Kimberly Lane Kascak, Cynthia Dodds

“…DIF findings support a potential reduction in the recommended number of PASMA administrations per individual. Future research will focus on establishing rater reliability and external validity. …”
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VARIETAL ASSESSMENT, HERITABILITY AND CORRELATION ANALYSIS OF ADAPTATION- AND PRODUCTION-RELATED TRAITS IN BREAD WHEAT LANDRACES OF THE ALGERIAN SAHARA OASES by M. Boulacel, T. Hadji, A. Ghennai, M. Hadji, A. Benlahbib, N. Souilah, H. Bendif

“…Furthermore, path coefficient analysis showed direct positive effects of number of grains per spike, weight of thousand grain and days to booting on grain yield. …”
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Asymptomatic Bacteriuria among Pregnant Women in Addis Ababa, Ethiopia: Prevalence, Causal Agents, and Their Antimicrobial Susceptibility by Ketema Bizuwork, Haile Alemayehu, Girmay Medhin, Wondwossen Amogne, Tadesse Eguale

“…Women whose urine samples carried greater than or equal to 105 colony-forming units (CFU) of bacteria per milliliter of urine when grown on plate count agar were considered positive for ASBU. …”
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Knowledge, Attitude, and Associated Factors towards Nonpharmacological Pain Management among Nurses Working at Amhara Region Comprehensive Specialized Hospitals, Ethiopia by Esayas Alemshet Tekletsadik, Abebaw Alemayehu Desta, Belayneh Shetie Workneh

“…Educational qualification, years of experience, working unit, nurse-to-patient ratio, and prolonged working hours per day were significantly associated with nurse’s adequate knowledge. …”
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Effects of using different levels of dietary chitosan on some immune indices and antioxidant defense system in Vannamei shrimp, Litopenaeus vannamei by Saeed Dayani, Valiallah Jafari, Roghayeh Safari, Seyed Hossein Hoseinifar

“…We prepared 4 groups, each with three repetitions, including the basal diet of zero (control), 1 g (treatment 1 = T1), 2 g (T2) and 4 g (T3) chitosan per kilogram of feed in a completely randomized design for 8 weeks. …”
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Compassion fatigue and associated factors among nurses working in Jimma Zone public hospitals, southwest Ethiopia: A facility based cross-sectional study. by Duguma Debela Ganeti, Bikila Dereje Fufa, Ebissa Bayana Kebede, Sheka Shemsi Seid, Birhanu Wogane Ilala, Nuritu Bacha Benti, Yeshitila Belay Belachew

“…Total experience [β = -0.04; 95%CI (-0.06, -0.01); p = 0.005], perceived social support [β = -0.13; 95% CI (-0.17, -0.08); p<0.001], self-compassion [β = -0.09; 95% CI (-0.14, -0.03); p = 0.003], support seeking [β = -0.23; 95% CI (-0.42, -0.04 p = 0.017], emergency ward [β = 0.36; 95% CI (0.2, 0.51); p <0.001], ICU [β = 0.38; 95% CI (0.21, 0.54); p<0.001], pediatric ward [β = 0.23; 95% CI (0.10, 0.36); p < 0.001] and average sleep hours per day [β = 0.46; 95% CI (0.35, 0.57); p<0.001] were statistically signifantly factors.…”
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Re-Engagement in Physical Activity Slows the Decline in Older Adults’ Well-Being – A Longitudinal Study by Hon Lon Tam PhD, Kai Chow Choi PhD, Ying Lau PhD, Leona Yuen Ling Leung DN, Alex Siu Wing Chan PhD, Lilin Zhou BSc, Eliza Mi Ling Wong PhD, Jonathan Ka Ming Ho DN

“…People aged 60 years and above were included, and they were categorized as active engagers if they reported engaging in at least 10 min of moderate and/or vigorous exercise consecutively per week in each survey year. Older adults’ well-being was evaluated using the healthy aging score, and geographical variations were visualized. …”
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Effects of nanoencapsulated essential oil blend in diet of Lohmann Brown hens on posture percentage, quality and egg oxidative stability by Gilmar Mendoza–Ordoñez, Miguel Callacná–Custodio, Vanessa Armas–Azabache, Bruno Loyaga–Cortéz, Roberto Ybañez–Julca, Daniel Asunción–Alvarez, Hugo Saavedra–Sarmiento, Aníbal Rodriguez–Vargas

“…The objective of the research was to evaluate the effect of mixtures of N–EOs in diets of Lohmann Brown hens on the percentage of laying, quality, and oxidative stability of the egg product. 600 birds were randomly distributed into five groups (n=150 per group), according to a completely randomized design, receiving the control group (T0) a conventional diet without N–EOs while the experimental groups received mixtures of N–EOs based on soursop (S), lemon (L) and eucalyptus (E) in different proportions: T1 (S: 33.4 , L:33.3%, E:33.3%), T2 (S:50%, L:25%, E:25%), T3 (S:25%, L:50%, E:25%) and T4 ( S:25%, L:25%, E:50%). …”
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Effects of Exercise Domain and Intensity on Sleep in Women and Men with Overweight and Obesity by Jonas Salling Quist, Mads Rosenkilde, Anne Sofie Gram, Martin Bæk Blond, Daniel Holm-Petersen, Mads Fiil Hjorth, Bente Stallknecht, Anders Sjödin

“…Sleep was assessed from 7-day/night accelerometry and questionnaires at baseline, 3 months, and 6 months. 92 participants were included in a per protocol analysis. At 3 months, sleep duration was longer in VIG (29 min/night [3; 55] (mean [95% CI]), p=0.03) but not in BIKE and MOD (p≥0.11) compared with CON and was not different between groups at 6 months (p≥0.36 vs. …”
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Ultrahigh-Performance Radio Frequency System-on-Chip Implementation of a Kalman Filter-Based High-Precision Time and Frequency Synchronization for Networked Integrated Sensing and... by Roghayeh Ghasemi, Patrick Fenske, Tobias Koegel, Markus Hehn, Ingrid Ullmann, Martin Vossiek

“…Due to the deterministic processing time inherent in the FPGA, the proposed synchronization method achieves exceptional precision, with clock offset deviations in the nanosecond range and clock rate deviations limited to only a few parts per billion, even across considerable distances between the network nodes.…”
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Effects of a foot-ankle strengthening programme on clinical aspects and gait biomechanics in people with knee osteoarthritis: protocol for a randomised controlled trial by Tania F Salvini, Glauko Dantas, Isabel C N Sacco, Ana F dos Santos, Ricky Watari, Alessandra B Matias, Paula R M S Serrao, Henrique Pott-Junior

“…Data will be analysed on intention-to-treat principles and a per protocol basis.Ethics and dissemination Investigators and sponsors will communicate trial results to participants and healthcare professionals through scientific databases and social media. …”
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SARS-CoV-2 SPIKE Antibody Levels can Indicate Immuno-Resilience to Re-infection: a Real-World Study by Yue Jin, Fei Yang, Christopher M. Rank, Stanley Letovsky, Peter Ramge, Simon Jochum

“…Study outcomes included the first symptomatic SARS-CoV-2 infection (per ICD-10 diagnostic codes, occurring ≥ 7 days post-antibody titer test), and severe SARS-CoV-2 infection, characterized by adverse outcomes including hospitalization, intensive care unit admission, intubation, mechanical ventilation, or death within 30 days of infection. …”
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Premalignant features of the prostate can be ameliorated by Uvaria chamae root extract: Modeling prostate cancer with cadmium and alternative treatment option in adult Wistar rats by Edem GD, Sakpa CL, Ezeuko VC

“…They were randomly divided into 10 groups of 6 animals per group (n=6). Group 1 received water and diet alone, group 2 received 3mg/kg of cadmium alone once weekly for 28days. …”
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