Vaskulitis pada Lupus Eritematosus Sistemik by Zikry Aulia Hidayat, Raveinal Raveinal

“…Pasien diberikan terapi dengan metil prednisolon intravena 2x125 mg selama 3 hari serta hidroksiklorokuin 1x200 mg per oral. Respon yang baik terlihat pada hari rawatan keenam dengan berkurangnya manifestasi vaskulitis secara signifikan. …”
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Day before late regimen vs standard split dose of low-volume PEG-CS for early morning colonoscopy: Multicenter randomized controlled trial by Luigi Pasquale, Giuseppe Grande, Rocco Maurizio Zagari, Paolo Biancheri, Antonio Pisani, Paola Da Massa Carrara, Bastianello Germanà, Enrico Ciliberto, Gianpaolo Cengia, Antonietta Lamazza, Patrizia Lorenzini, Mariavittoria V Carati, Liboria Laterza, Flavia Pigò, Desiree Picascia, Carmelo Stillitano, Matteo Pollastro, Elisabetta Dal Pont, Stefania Maraggi, Rita Conigliaro, Giuseppe Galloro

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PHARMACOECONOMICAL RESEARCH OF THE USE OF SORAFENIB IN MALIGNANT TUMORS by M. Y. Frolov, N. A. Avksentjev, I. G. Rusakov, E. V. Derkach

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The Utility of Synovial Fluid Interleukin-10 in Diagnosing Chronic Periprosthetic Joint Infection: A Prospective Cohort Study by Zou Y, Yang Y, Yang J, Zhang Y, Zhao C, Qin L, Hu N

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Adipose Tissue-Derived Stromal Cells Induce a Highly Trophic Environment While Reducing Maturation of Monocyte-Derived Dendritic Cells by Morten Juhl, Bjarke Follin, Monika Gad, Jesper Larsen, Jens Kastrup, Annette Ekblond

“…ASCs were isolated from healthy voluntary donors, expanded using a human platelet lysate in bioreactors, and cryopreserved as per clinical use. Monocyte-derived dendritic cells were generated by isolation of monocytes and differentiation with GM-CSF and IL-4. …”
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Does providing atrial fibrillation patients, after pulmonary vein isolation, with a 1-lead ECG device relieve the emergency department?-A historically controlled prospective trial. by Jasper L Selder, Mark J Mulder, Willem R van de Vijver, Philip M Croon, Leontine E Wentrup, Stéphanie L van der Pas, Jos W R Twisk, Igor I Tulevski, Albert C Van Rossum, Cornelis P Allaart

“…There was no statistically significant difference in the number of all-cause ED visits (63 vs 68 per 100 pts, respectively, p = 0.72), ED visits for possible rhythm disorders, or ED visits for definite rhythm disorders between the two groups. …”
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Time-resolved measurement of neutron energy isotropy in a sheared-flow-stabilized Z pinch by R.A. Ryan, P.E. Tsai, A.R. Johansen, A.E. Youmans, D.P. Higginson, J.M. Mitrani, C.S. Adams, D.A. Sutherland, B. Levitt, U. Shumlak

“…The FuZE device operated at −25 kV charge voltage has resulted in average plasma currents of 370 kA and D–D fusion neutron yields of $4\times10^7 \pm 4\times10^6$ neutrons per discharge. Measurements of the neutron energy isotropy under these operating conditions demonstrates the energy of deuteron beams is less than $7.4 \pm 5.6^\mathrm{(stat)} \pm 3.7^\mathrm{(syst)}$  keV. …”
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The association between sleep duration and myopia among Chinese school-age students: mediation effect of physical activity by Haiqing Feng, Yuexia Gao, Na An, Yitong Lu, Jianping Huang, Weiping Yang, Qingyun Lu

“…Each participant completed a standardized interview in which their were asked about their vision, level of physical activity and average hours of sleep per day over the past month. Visual acuity examinations were conducted by the testing team’s ophthalmology professionals and they were categorized into two groups based on pre-set criteria: myopic and non-myopic. …”
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Cool Neighbors: Combining Artificial Intelligence and Citizen Science to Chart the Sun’s Cosmic Neighborhood by Aaron Meisner, Dan Caselden, Austin Humphreys, Grady Robbins, Eden Schapera, J. Davy Kirkpatrick, Adam Schneider, L. Clifton Johnson, Marc Kuchner, Jacqueline Faherty, Sarah Casewell, Federico Marocco, Adam Burgasser, Daniella Bardalez Gagliuffi

“…Through analysis of more than 10 million total Zooniverse classifications from the combination of Cool Neighbors and Backyard Worlds: Planet 9, among other results, we find (1) Cool Neighbors volunteers perform ~3x more classifications per unit of time invested than Backyard Worlds: Planet 9 volunteers, and (2) each registered Cool Neighbors participant performs ~2–5x more classifications than each registered Backyard Worlds: Planet 9 participant. …”
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Beclin-1 as a potential prognostic marker in correlation with E-cadherin in oral lichen planus and oral squamous cell carcinoma: an immunohistochemical analysis by Heba N. Shalash, Radwa R. Hussein, Fatma Seragel-Deen

“…The function of Beclin-1, as per a marker for autophagy, still needs to be verified in oral premalignant lesions and their progression to OSCC. …”
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The effects of active play interventions on children’s fundamental movement skills: a systematic review by Xinmiao Zhang, Changhao Tang, Miao Geng, Kai Li, Cong Liu, Yujun Cai

“…The AP interventions in these 9 studies exhibited varying characteristics, with individual intervention durations ranging from 45 to 60 min, intervention frequencies ranging from once a week to four times per week, and intervention periods spanning from 4 weeks to 6 months. …”
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Silent witnesses: unveiling the epidemic of femicides in North-west Tshwane, South Africa – a decade of analysis by Yaseen Bismilla, K. K. Hlaise, C. Van Wyk

“…The average incidence rate of femicides was 11.2 per 100,000 female population, showing a general decline over the study period, except for notable increases in 2013 and 2016. …”
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Oral Supplementation with Three Vegetable Oils Differing in Fatty Acid Composition Alleviates High-Fat Diet-Induced Obesity in Mice by Regulating Inflammation and Lipid Metabolism by Waleed Aldamarany, Huang Taocui, Deng Liling, Yang Wanfu, Geng Zhong

“…Mice were divided into five groups: ND, mice fed a normal diet; HFD, mice fed a high-fat diet; PSO, SFO, and TSO, mice fed a high-fat diet supplemented with PSO, SFO, and TSO at 2 g/kg body weight per day, respectively. Our findings showed that oral supplementation with all three oils for 8 weeks significantly reduced body weight, tissue weight, insulin resistance index, serum levels of alanine aminotransferase (ALT), aspartate aminotransferase (AST), and free fatty acids (FFA), and markedly alleviated hyperglycemia, hyperlipidemia, and hepatic steatosis in obese mice. …”
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Prognostic impact of depth of response and early tumour shrinkage in patients with -mutated metastatic colorectal cancer treated with targeted therapy by Guglielmo Vetere, Marco Maria Germani, Carlotta Antoniotti, Lisa Salvatore, Filippo Pietrantonio, Sara Lonardi, Maria Bensi, Filippo Ghelardi, Maria Alessandra Calegari, Rossana Intini, Alessandro Minelli, Francesco Giulio Sullo, Chiara Boccaccio, Ada Taravella, Alberto Puccini, Daniele Lavacchi, Laura Noto, Massimiliano Salati, Mario Scartozzi, Chiara Cremolini

“…In the multivariable models, DpR significantly correlated with longer PFS as a dichotomous variable, according both to conventional (hazard ratio (HR) DpR   ⩾ 30% : 0.52, 95% CI: 0.30–0.90, p  = 0.02) and median cut-off values (HR DpR⩾15% : 0.55, 95% CI: 0.33–0.92, p  = 0.03), and as a continuous variable (HR per 10% increment: 0.88, 95% CI: 0.78–0.98, p  = 0.02), while correlations with OS were not confirmed. …”
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Point-of-care lung ultrasonography for early identification of mild COVID-19: a prospective cohort of outpatients in a Swiss screening center by Olivier Hugli, Jean-Yves Meuwly, Noémie Boillat-Blanco, Pierre-Nicolas Carron, Siméon Schaad, Thomas Brahier, Mary-Anne Hartley, Jean-Baptiste Cordonnier, Luca Bosso, Tanguy Espejo, Olivier Pantet

“…This study evaluates the diagnostic performance of lung ultrasound (LUS), an affordable, consumable-free point-of-care tool, for COVID-19 screening.Design, setting and participants This prospective observational cohort included adults presenting with cough and/or dyspnoea at a SARS-CoV-2 screening centre of Lausanne University Hospital between 31 March and 8 May 2020.Interventions Investigators recorded standardised LUS images and videos in 10 lung zones per patient. Two blinded independent experts reviewed LUS recording and classified abnormal findings according to prespecified criteria to investigate their predictive value to diagnose SARS-CoV-2 infection according to PCR on nasopharyngeal swabs (COVID-19 positive vs COVID-19 negative).Primary and secondary outcome measures We finally combined LUS and clinical findings to derive a multivariate logistic regression diagnostic score.Results Of 134 included patients, 23% (n=30/134) were COVID-19 positive and 77% (n=103/134) were COVID-19 negative; 85%, (n=114/134) cases were previously healthy healthcare workers presenting within 2–5 days of symptom onset (IQR). …”
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Photodynamic Therapy with Protoporphyrin IX Precursors Using Artificial Daylight Improves Skin Antisepsis for Orthopedic Surgeries by Tiziano A. Schweizer, Julia S. Würmli, Julia Prinz, Maximilian Wölfle, Roger Marti, Hendrik Koliwer-Brandl, Ashley M. Rooney, Vanni Benvenga, Adrian Egli, Laurence Imhof, Philipp P. Bosshard, Yvonne Achermann

“…On day 4, three (30%) participants per group showed positive cultures post antisepsis. …”
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Acupuncture Dosage and Its Correlation with Effectiveness in Patients with Chronic Stable Angina: A Systematic Review and Meta-Analysis of Randomized Controlled Trial by Huang D, Li Y, Zheng X, Hu J, Tang H, Yin Y, Wu Z, Kong L

“…Studies were categorized into high (HDG), moderate (MDG), and low (LDG) dosage groups based on acupuncture characteristics: the number of acupoints, total sessions, frequency per week, and the need for “Deqi”.Results: Of the 807 citations screened, 16 studies (1240 patients) were included: 3 studies in LDG, 10 in MDG, and 3 in HDG. …”
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Bacterial pathogens dynamic during multi-species infections by Barny, Marie-Anne, Thieffry, Sylvia, Gomes de Faria, Christelle, Thebault, Elisa, Pédron, Jacques

“…The bacteria present in each tested community were representative of 2 different species, with 3 strains per species. These communities were inoculated in potato tubers or on synthetic media and their outcome was followed by amplification and Illumina sequencing of the discriminatory housekeeping gene gapA. …”
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From pollution to sustainable environment: unlocking the role of energy intensity and renewable energy in highly pollutant nations by Zhi Zhen Zhou, Muhammad Shahid Hassan, Muhammad Ibrahim Saeed, Haider Mahmood, Rukhsana Kalim, Amira Houaneb

“…A period of 1990–2021 is utilized for data analyses as per data availability of all analyzed countries. …”
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Gastrointestinal absorption and its regulation of hawthorn leaves flavonoids by Junwei Chow, Xiaolei Yang, Jiarong Hu, Qiuxia Yu, Yu Zhong, Xinyi Hu, Jingru Liang, Chenyang Zhu, Shiwei Yan, Longzhou Li, Haiyang Liu, Tiandian Wang, Zihan Wang, Long Gao, Guo Ma

“…GLV, RHV, VIT and RUT demonstrated similar and poor absorption in rat stomach (absorption percentage per hour (A), (1.78 ± 0.14 ~ 5.69 ± 0.51)%·h−1) and small intestine (absorption rate ( $$\:{k}_{a}^{app}$$ , (0.012 ± 0.006 ~ 0.055 ± 0.003) h−1), extent (A, (1.28 ± 0.14 ~ 2.82 ± 0.19)% ·h−1) and potential (P app, (0.31 ± 0.05 ~ 1.41 ± 0.08)×10−7 cm·sec−1)), while HP showed relatively better absorption (P app, (2.55 ± 0.15 ~ 4.27 ± 0.36)×10−7 cm·sec−1) in rat small intestine. …”
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