Association of Habitual Physical Activity Measured by an Accelerometer with High-Density Lipoprotein Cholesterol Levels in Maintenance Hemodialysis Patients by Ryota Matsuzawa, Atsuhiko Matsunaga, Toshiki Kutsuna, Akira Ishii, Yoshifumi Abe, Kei Yoneki, Manae Harada, Mio Ishibashi, Yasuo Takeuchi, Atsushi Yoshida, Naonobu Takahira

“…An accelerometer measured physical activity as the number of steps per day over five consecutive days, and multiple regression evaluated the association between physical activity and HDL-C levels. …”
Get full text

Two studies in one: A propensity-score-matched comparison of fingolimod versus interferons and glatiramer acetate using real-world data from the independent German studies, PANGAEA... by Jonathan Alsop, Jennie Medin, Christian Cornelissen, Stefan Viktor Vormfelde, Tjalf Ziemssen

“…Patients in PANGAEA (n = 1287) experienced 48% fewer relapses per year than those in PEARL (n = 429; annualized relapse rate ratio: 0.52; p < 0.001). …”
Get full text

The First Comprehensive Examination of Male Morphometrics and the Operational Sex Ratio of the Black Sea Turtle (<i>Chelonia mydas agassizii</i>) Population in Colola, Michoacan, M... by Carlos Delgado-Trejo, Miguel Ángel Reyes-López, David Guillermo Pérez-Ishiwara, Ricardo Lemus-Fernández, Fátima Yedith Camacho-Sánchez, Cutzi Bedolla-Ochoa

“…Among the mating groups, 34.3% consisted of only one male, while 65.7% included two or more males, with the number of males per female ranging from 2 to 17. The analysis revealed that there are interannual and monthly variations in OSR values, with observations showing a range from 2.3:1 (male to female) in 2023 to 4.3:1 (male to female) in 2009. …”
Get full text

Assessing the robustness and implications of econometric estimates of climate sensitivity by Trude Storelvmo, Menghan Yuan, Thomas Leirvik, Kari Alterskjær, Peter C B Phillips, Chris Smith

“…Earth’s transient climate response (TCR) quantifies the global mean surface air temperature change due to a doubling of atmospheric $\mathrm{CO_2}$ concentration after 70 years of a compounding 1% per year increase. TCR is highly correlated with near-term climate projections, and thus of relevance for climate policy, but remains poorly constrained in part due to uncertainties in the representation of key physical processes in Earth System Models (ESMs). …”
Get full text

Comparing the cost-benefit of breast cancer screening programs in rural and urban areas across four economic zones in China: a Markov modeling analysis by Dachuang Zhou, Kejia Zhou, Wenjuan Wang, Hanqiao Shao, Hongliu Zhang, Wenxi Tang

“…Results Using a willingness-to-pay threshold of three times the local per capita Gross domestic product (GDP), the recommended strategies varied across regions. …”
Get full text

A Fortified Method to Screen and Detect Left Ventricular Hypertrophy in Asymptomatic Hypertensive Adults: A Korean Retrospective, Cross-Sectional Study by Hyo Eun Park, Sung-Bin Chon, Sang Hoon Na, Heesun Lee, Su-Yeon Choi

“…The diagnostic rule summed female, age≥65 y, BMI≥25 kg/m2, SLVA≥35 mm, and CTR≥0.50 (scoring 1 per each). Its c-statistics was 0.700 (95% CI: 0.653, 0.747), significantly higher (p<0.001) than that of SLVA≥35 mm, 0.522 (95% CI: 0.472, 0.572). …”
Get full text

Cost‐of‐illness analysis of chronic urticaria clinical management in five countries of Latin America by Jorge Sánchez, Leidy Álvarez, José Ignacio Larco, Luis Ensina, Guillermo Guidos‐Fogelbach, Cesar A. Reyes‐López, German D. Ramon, Karla Robles‐Velasco, Ivan Cherrez‐Ojeda

“…Results According to the projected costs, Brazil had the highest urticaria cost per patient/year (7009.4 USD), followed by Mexico (3695.1 USD), Ecuador (3132.8 USD), Peru (2693.9 USD), and Colombia (2392.8 USD); the cost and the frequency of use of omalizumab and antihistamines explain the total cost differences between countries. …”
Get full text

Safety and effectiveness of dual therapy for Helicobacter pylori infection and the effect on the glycated hemoglobin level in type 2 diabetes by Jie Zhang, Xin Cao, Kai Ma, Yizhou Jiang, Xiangrong Qin, Xiaoyong Wang

“…The eradication rate in the intention-to-treat analysis and per-protocol analysis was 84.00% (63/75) and 87.14% (61/70), respectively. …”
Get full text

Inheritance of cleistogamy in interspecific hybridization of Gossypium barbadense L. by T. I. Mukhiddinov, A. A. Abdullayev, E. Kuchkarov, A. H. Choriev, S. K. Jumaev

“…., three plants with chasmogamous flowers per one cleistogamous. The segregation Fb is 1:1; i.e., 1 chasmogamous : 1 cleistogamous. …”
Get full text

Adverse events following immunization surveillance on two types of enterovirus 71 vaccines: A real-world comparative study in China by Yiqing Zhu, Yihan Wang, Jinghui Wang, Yafei Wang, Li Sun, Shiheng Cui, Jing Li, Yu Guo

“…With 477 AEFI reported, the reported rate was 14.21 per 100,000 doses. Most cases occurred in infants under one year of age (45.91%). …”
Get full text

Stem Cell Therapy for the Treatment of Amyotrophic Lateral Sclerosis: Comparison of the Efficacy of Mesenchymal Stem Cells, Neural Stem Cells, and Induced Pluripotent Stem Cells by Lauren Frawley, Noam Tomer Taylor, Olivia Sivills, Ella McPhillamy, Timothy Duy To, Yibo Wu, Beek Yoke Chin, Chiew Yen Wong

“…With an incidence rate of about 4.42 cases per 100,000 people annually, ALS severely impacts motor function and quality of life, causing progressive muscle atrophy, spasticity, paralysis, and eventually death. …”
Get full text

Preliminary evaluation of the FastCAP for users of the Nurotron cochlear implant by Xue-Ying Yang, Sui Huang, Qian-Jie Fu, John Galvin, Bing Chen, Ji-Sheng Liu, Duo-Duo Tao

“…FastCAPs and ECAPs were measured across five electrodes and four stimulation levels per electrode. The FastCAP stimulation rate (33.3 Hz) is also faster than the ECAP rate (2.5 Hz).ResultsResults showed strong correlations between ECAPs and FastCAPs for N1 latency (r = 0.84, p &lt; 0.001) and N1 amplitude (r = 0.97, p &lt; 0.001). …”
Get full text

Association between combined healthy lifestyles and infertility: a cross-sectional study in US reproductive-aged women by Xiaofeng Ye, Xiaoxia Song, Sihang Zhou, Guoqing Chen, Liping Wang

“…A healthy lifestyle score was created based on healthy diet (top two-fifths of the Healthy Eating Index-2015 score), low-to-moderate alcohol drinking (1–14 g/day), optimal waist circumference (less than 80 cm), adequate physical activity (at least 150 min of moderate-to-vigorous leisure-time exercise per week), and current nonsmoking. Weighted logistic regression analysis was applied to assess the link between healthy lifestyle scores and the risk of infertility, adjusting for potential confounders. …”
Get full text

Daily oscillation of the excitation/inhibition ratio is disrupted in two mouse models of autism by Michelle C.D. Bridi, Nancy Luo, Grace Kim, Benjamin J. Menarchek, Rachel A. Lee, Bryan Rodriguez, Daniel Severin, Christian Wesselborg, Caroline O’Ferrall, Ruchit Patel, Sarah Bertrand, Sujatha Kannan, Alfredo Kirkwood, Cristian Moreno, Altagracia Contreras

“…These findings raise the possibility that ASD-related phenotypes may be produced by a mismatch between E/I and behavioral state, rather than alterations to overall E/I levels per se.…”
Get full text

The role of highly dispersed silica nanoparticles in the realization of the effects of granulosa on the maturation and fertilization competence of <i>Sus scrofa domesticus</i> oocy... by T. I. Kuzmina, I. V. Chistyakova, A. O. Prituzhalova, D. N. Tatarskaya

“…In the present study, a model of culture medium for gametes (NCSU-23 with 10 % homologous follicular fluid, 10 IU hCG and 10 IU eCG) modernized by the addition of 1·106 granulosa cells (GCs) per ml and 0.001 % of highly dispersed silica nanoparticles (HDSn) is proposed for use in the IVM and IVF technology of donor porcine oocytes. …”
Get full text

Tramadol use and incident dementia in older adults with musculoskeletal pain: a population-based retrospective cohort study by Si Nae Oh, Hye Jun Kim, Jae Yong Shim, Kyuwoong Kim, Seogsong Jeong, Sun Jae Park, Sang Hyun Lee, Joong Won Ha, Sang Min Park

“…Over a maximum of 14-year follow-up, the incidence rates (events per 1000 person-years) of all-cause dementia were 6.1 for nonusers, 6.2 for those with cumulative tramadol use of 1–14 days, 7.7 for those with 15–90 days of use, and 8.0 for those with > 90 days of use. …”
Get full text

Characterization of the genomic landscape in liver oligometastatic NSCLC by Rongxin Liao, Guangming Yi, Lu Shen, Xiao Xiao, Chuan Zeng, Liangzhong Liu, Hongjun Tang, Shunping Huang, Xiaoyue Zhang, Zaicheng Xu, Zhenzhou Yang, Yuan Peng

“…Results A total of 206 mutated genes in 32 patients were detected, with a median of 4 mutations per sample. The most frequent alterations (> 10%) in liver oligometastasis were TP53 (72%), EGFR (50%), RB1 (19%) and SMARCA4 (12%). …”
Get full text

The Combination of D-TACE-HAIC, Lenvatinib, and PD-1 Inhibitors Shows Significant Clinical Efficacy in Patients with Unresectable Hepatocellular Carcinoma by Wu Y, Zhu J, Zhang H, Xia N

“…In total, 60 patients underwent treatment with drug-eluting beads-TACE-hepatic arterial infusion chemotherapy (D-TACE-HAIC) combined with lenvatinib and PD-1 inhibitors (Group A), while 21 underwent combined TACE and sorafenib treatment (Group B).Results: In this study cohort, the rate of surgical conversion in Group A was significantly higher than that in Group B (33.3% vs 9.5%). As per the Revised Evaluation Criteria for Clinical Efficacy in Solid Tumors (mRECIST) criteria, the objective remission rate in Group A was significantly higher than that in Group B (86.6% vs 33.4%). …”
Get full text

A new hybrid distance and similarity based scenario reduction approach for stochastic economic operation of microgrid by Gaurav Gangil, Amit Saraswat, Sunil Kumar Goyal

“…This stochastic model is aimed at generating the optimum schedules for various dispatchable generating resources such as micro-turbines, fuel cells, utility grid, energy storage devices as per the availability of the various VRE resources to meet the uncertain demand for a day-to-day microgrid operation. …”
Get full text

The Impact of Migraine on the Whole Life Course of Patients: Results from the OVERCOME (Japan) 2nd Study by Daisuke Danno, Shiho Suzuki, Tsubasa Takizawa, Ryotaro Ishii, Masayuki Hamakawa, Yoshinori Tanizawa, Satoshi Osaga, Mika Komori

“…The migraine group had mean (SD) 3.5 (5.2) MHDs; 24.2–56.7% had moderate-to-very severe disease burden per various PRO instruments. Headaches started when respondents with migraine were 17.8 years old; 86.7% started over-the-counter medications at 19.4 years of age. …”
Get full text