Computational Study Protocol: Leveraging Synthetic Data to Validate a Benchmark Study for Differential Abundance Tests for 16S Microbiome Sequencing Data [version 2; peer review: 2... by Clemens Kreutz, Eva Kohnert

“…The 14 differential abundance tests will be applied to synthetic and experimental datasets, evaluating the consistency of significant feature identification and the number of significant features per tool. Correlation analysis and multiple regression will explore how differences between synthetic and experimental data characteristics may affect the results. …”
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Once-weekly semaglutide doubles the five-year risk of nonarteritic anterior ischemic optic neuropathy in a Danish cohort of 424,152 persons with type 2 diabetes by Jakob Grauslund, Andreas Abou Taha, Laleh Dehghani Molander, Ryo Kawasaki, Sören Möller, Kurt Højlund, Lonny Stokholm

“…Semaglutide exposure was associated with a higher incidence rate (0·228 vs. 0·093 per 1000 person-years, p < 0·001) and independently predicted a higher risk of upcoming NAION (HR 2·19, 95% confidence interval 1·54 − 3·12), even when multiple other factors were taken into account. …”
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Characterising COVID-19 school and childcare outbreaks in Canada in 2021: a surveillance study by Kaitlin Patterson, Erin McGill, Demy Dam, Anna Bellos, Cameron Mark Coulby, Rachel McCormick

“…Most school and childcare outbreaks reported fewer than 10 cases per outbreak. During the start of the 2021–2022 school year (September 2021), there were fewer outbreaks in secondary schools and fewer cases among those aged 12+ years compared with January–June of 2021.Conclusion During the study period, there was no observed association between an increase in school and childcare outbreaks and an increase in incidence rates in community case data. …”
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Barriers and enablers to opioid deprescription: A qualitative study. by Rebecca Lawrence, Everett Versteeg, Andrea Pike, Holly Etchegary, Amanda Hall

“…<h4>Background</h4>Canada has the fourth highest per capita rate of opioid prescriptions in the world, contributing to the country's opioid crisis. …”
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Assessment of Management Factors Influencing Vaccination Against Cholera in the Health District of Katana, the Democratic Republic of the Congo by Irène Ntererwa-Nsimire, Leonid M Irenge, Paulin B Mutombo, Eric M Mafuta, Jean-Luc Gala, Dosithée Ngo-Bebe

“…The survey targeted households (n = 404) with 1 adult person per household responding on behalf of all the members of the household and key informants (KI) who were health workers (n = 6) in 5 health areas of the Katana health district. …”
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Eliciting Emotions: Investigating the Use of Generative AI and Facial Muscle Activation in Children’s Emotional Recognition by Manuel A. Solis-Arrazola, Raul E. Sanchez-Yanez, Ana M. S. Gonzalez-Acosta, Carlos H. Garcia-Capulin, Horacio Rostro-Gonzalez

“…The study involves generating a database of 280 images (40 per emotion) of children expressing various emotions. …”
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Exogenous Application of Lanthanum Chloride to Rice at Booting Stage Can Increase Chlorophyll Content, Modulate Chlorophyll Fluorescence and Promote Grain Yield Under Deficit Irrig... by Peng Liu, Xilin Fang, Yue Wang, Xin Yang, Qiang Li

“…Under deficit irrigation, this treatment significantly enhanced grain yield by increasing the thousand-grain weight, spikelet filling rate, and number of grains per panicle. These results suggest that spraying 100 mg·L⁻¹ lanthanum chloride at the booting stage under deficit irrigation can effectively increase the chlorophyll content, thereby increasing the light energy conversion efficiency of the PS II reaction center, ultimately resulting in increased spikelet filling rate and grain yields.…”
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A Case Report of Bowel Perforation in a Gravid COVID-19 Patient by A. T. Guiritan, J. G. Cataluña

“…Increasing residuals were noted per nasogastric tube (NGT). Serial scout film of the abdomen (SFA) and medical management were performed. …”
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Genetinių tyrimų svarba Parkinsono ligos diagnostikoje by Dominika Dakinevičiūtė, Jolita Čičelienė

“…Apžvalgai atrinkti 9 straipsniai.Rezultatai. Žinoma, kad per 20 genų yra susiję su Parkinsono ligos pasireiškimu. …”
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Phenolic Profile and Antioxidant Activity of Crude Extracts from Microalgae and Cyanobacteria Strains by Idaira Jerez-Martel, Sara García-Poza, Gara Rodríguez-Martel, Milagros Rico, Cristina Afonso-Olivares, Juan Luis Gómez-Pinchetti

“…The strain Euglena cantabrica showed the highest concentration of phenolic compounds, particularly gallic and protocatechuic acids (5.87 and 2.97 mg per gram of dried biomass, resp.). Aqueous and methanolic extracts of microalgae Euglena cantabrica also exhibited the highest antioxidant activity, probably due to the presence of the high contents of phenolics.…”
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Risk assessment of fine particulate matter exposure attributed to the presence of the cement industry by A. Mallongi, S. Stang, R.D.P. Astuti, A.U. Rauf, M.F. Natsir

“…The Monte Carlo Simulation model was used to estimate the uncertainty and sensitivity analysis of parameters.FINDINGS: The average fine particulate matter concentration was 23.68 micrograms per cubic meter, above the air quality guidelines of the World Health Organization. …”
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Components and predictability of pollutants emission intensity by Z. Farajzadeh, M.A. Nematollahi

“…Among the components, energy structure, population-labor ratio, and trade openness showed an intensity decreasing effect, while urban per capita output, urbanization, energy intensity, and industrial output-trade ratio contributed to higher emission intensity of the pollutants. …”
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Relationship between economic development, forest resources, and forest fires: European context by Olena Dobrovolska, Knut Schmidtke, Viktoriia Hnatushenko, Svitlana Sytnyk, Iryna Dmytriieva

“…Studying the dynamics of forest cover indicators (the share of forests in the total area of the country and forest area per capita), weighted within the internationally recognized regions of Europe, it is confirmed that the level of forest cover of European countries is gradually increasing. …”
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Impact of HPV Catch-Up Vaccination on High-Grade Cervical Lesions (CIN2+) Among Women Aged 26–30 in Northern Norway by Amanda Sørensen Jørgensen, Gunnar Skov Simonsen, Sveinung Wergeland Sørbye

“…Using linear regression, we assessed trends in high-grade lesion incidence per 1000 screened women and the association between vaccination status and HPV-16/18 incidence. …”
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Successful management of refractory epilepsy in creatine transporter deficiency with cannabidiol and clobazam: A case report by Maria Borrell‐Pichot, Carmen Fons, Susana Boronat, Alba Sierra‐Marcos

“…He had an average of 10–20 focal motor seizures with impaired consciousness per month. He had tried several ASMs without significant improvement. …”
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Physical functioning outcome measures in the lumbar spinal surgery population and measurement properties of the physical outcome measures: protocol for a systematic review by Alison B Rushton, Jai Mistry, Michael J Lukacs, Katie L Kowalski, Maren Goodman

“…Results for each measurement property per physical outcome measure will be quantitatively pooled if there is adequate clinical and methodological homogeneity or qualitatively synthesised if there is high heterogeneity in studies.Ethics and dissemination Ethics approval is not required. …”
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Time to Relapse and Relapse Predictors in Patients with Schizophrenia at Ayder Comprehensive Specialized Hospital, Northern Ethiopia by Habtamu Endashaw Hareru, Kebede Embaye Gezae, Daniel Sisay W/tsadik, Gebremedhin Berhe Gebregergs

“…In this study, the incidence of relapse was 2.9 per 100 person-months (PMs) and the median time to relapse of 13 months (interquartile range: 6–23 months). …”
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Neuroprotective Effects of the Ethanolic Leaf Extract of Crassocephalum crepidioides (Asteracaeae) on Diazepam-Induced Amnesia in Mice by Beppe Galba Jean, Folefack Alice Irène, Atsamo Albert Donatien, Ngatanko Aïbassou Hervé-Hervé, Barga Mpoo Bertrand, Allah-Doum Nanou Gael, Nguedia Ymele Merline, Zemo Gamo Franklik, Dongmo Alain Bertrand, Dimo Théophile

“…The normal control and negative control groups received 2% ethanol per os, the positive control group received piracetam (150 mg/kg, p.o), and three experimental groups were treated with three doses of ethanolic leaf extract of Cc (100, 200, and 400 mg/kg, p.o). …”
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Limosilactobacillus mucosae FZJTZ26M3 prevents NAFLD in mice through modulation of lipid metabolism and gut microbiota dysbiosis by Danting Dang, Bowen Li, Mengfan Ding, R. Paul Ross, Catherine Stanton, Jianxin Zhao, Bo Yang, Wei Chen

“…Four-week-old male C57BL/6J mice were divided into 4 groups (n = 8 per group, Control, Model, FZJTZ26M3, FGSYC17L3). …”
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Trends, gender, and racial disparities in patients with mortality due to paroxysmal tachycardia: A nationwide analysis from 1999-2020. by Aman Goyal, Humza Saeed, Saif Yamin, Abdullah, Wania Sultan, Muhammad Khubaib Arshad, Samia Aziz Sulaiman, Mah I Kan Changez, Gauranga Mahalwar

“…Overall, AAMR decreased from 4.8 to 3.7 per 100,000 population between 1999 and 2020, despite showing a significant increase from 2014 to 2020 (APC: 4.33; 95% CI: 3.53 to 5.56). …”
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