Durvalumab and tremelimumab in patients with advanced rare cancer: a multi-centre, non-blinded, open-label phase II basket trialResearch in context by Abha A. Gupta, Anna Tinker, Derek Jonker, Rahma Jamal, Hal Hirte, Eric W. Winquist, Quincy Chu, Christian Kollmannsberger, Ralph Wong, Thierry Alcindor, Torsten O. Nielsen, Ming Tsao, Tricia R. Cottrell, Diane Provencher, John Hilton, Monika K. Krzyżanowska, Christine Elser, Sebastien Hotte, Joana Sederias, Siwei Zhang, Wei Tu, Janet Dancey

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Untethering the Nuclear Envelope and Cytoskeleton: Biologically Distinct Dystonias Arising from a Common Cellular Dysfunction by Nadia A. Atai, Scott D. Ryan, Rashmi Kothary, Xandra O. Breakefield, Flávia C. Nery

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Investigating the trustworthiness of research evidence used to inform public health policy: a qualitative interview study on the use of predatory journal citations in policy docume... by Marc A. Albert, Manoj M. Lalu, Agnes Grudniewicz

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A Review of Factors Influencing the Banking of Collected Umbilical Cord Blood Units by David Allan, Tanya Petraszko, Heidi Elmoazzen, Susan Smith

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Umbrella-Review, Evaluation, Analysis and Communication Hub (U-REACH): a novel living umbrella review knowledge translation approach by Marco Solmi, David Moher, Samuele Cortese, Corentin J Gosling, Richard Delorme, Joaquim Radua

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Diagnosis and management of septal deviation and nasal valve collapse - a survey of Canadian otolaryngologists by Yiqiao Wang, James P. Bonaparte

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Cost Analysis of Noninvasive Helmet Ventilation Compared with Use of Noninvasive Face Mask in ARDS by Kwadwo Kyeremanteng, Louis-Philippe Gagnon, Raphaëlle Robidoux, Kednapa Thavorn, Dipayan Chaudhuri, Daniel Kobewka, John P. Kress

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Prevalence of non-contrast CT abnormalities in adults with reversible cerebral vasoconstriction syndrome: protocol for a systematic review and meta-analysis by Dean A Fergusson, Dar Dowlatshahi, Brian Dewar, Michel Shamy, Naomi Niznick, Risa Shorr, Ryan Daniel Gotesman

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Comparative end-of-life communication and support in hospitalised decedents before and during the COVID-19 pandemic: a retrospective regional cohort study in Ottawa, Canada by Shirley H Bush, Monisha Kabir, Peter Lawlor, James Downar, Brandi Vanderspank-Wright, Sarina Isenberg, Peter Tanuseputro, Akshai Iyengar, Claire Dyason, Julie Lapenskie, Colleen Webber, Henrique Parsons, Samantha Rose Adeli, Ella Besserer, Leila Cohen, Valérie Gratton, Rebekah Murphy, Grace Warmels, Adrianna Bruni, Chelsea Noel, Brandon Heidinger, Koby Anderson, Kyle Arsenault-Mehta, Krista Wooller, Daniel Bedard, Paula Enright, Isabelle Desjardins, Khadija Bhimji

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Evaluating the effectiveness of adjuvant radiotherapy in addition to surgery versus surgery alone at improving oncologic outcomes for early stage buccal carcinoma: a systematic rev... by Corliss Ann Elizabeth Best, Alexandra Elizabeth Quimby, Brittany Ann Barbara Best, Dean Fergusson, Hussain Alsaffar

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Exploring the perspectives of new-in-practice specialists about the Health Advocate role: “I didn’t even know where to start” by Jacqueline Dorothy Cochrane, Nancy Dudek, Kelsey Crawford, Lindsay Cowley, Kori A LaDonna

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A Data Quality Control Program for Computer-Assisted Personal Interviews by Janet E. Squires, Alison M. Hutchinson, Anne-Marie Bostrom, Kelly Deis, Peter G. Norton, Greta G. Cummings, Carole A. Estabrooks

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Modelling Improvements in Cell Yield of Banked Umbilical Cord Blood and the Impact on Availability of Donor Units for Transplantation into Adults by Natasha Kekre, Jennifer Philippe, Ranjeeta Mallick, Susan Smith, David Allan

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The Association between Intertwin Difference in First Trimester Crown-Rump Length, Nuchal Translucency, and Birth Weight Discordance in Twin Pregnancies: A Retrospective Cohort Stu... by Zachary Michael Ferraro, Tinghua Zhang, Felipe Moretti, Karen Fung-Kee-Fung

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A quality improvement initiative aimed at reducing service strain and improving physician wellness in internal medicine by Jessica Evans, Sydney Ruller, Krista Wooller, Delvina Hasimja Saraqini, Mathilde Gaudreau-Simard

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Assessing the language availability, readability, suitability and comprehensibility of heat-health messaging content on health authority webpages and online resources in Canada by Emily J. Tetzlaff, Kristina-Marie T. Janetos, Katie E. Wagar, Farah Mourad, Melissa Gorman, Victor Gallant, Glen P. Kenny

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Are interventions for low-income groups effective in changing healthy eating, physical activity and smoking behaviours? A systematic review and meta-analysis by Stephan U Dombrowski, Marie Johnston, Nicola McCleary, Eleanor R Bull

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Integration of planetary health in undergraduate and postgraduate medical education: protocol for a scoping review by Lindsey Sikora, Daniel I McIsaac, Husein Moloo, Rajajee Selvam, Nieve Seguin, Lisa Zhang, Ariane Lacaille-Ranger

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Knowledge and motivations of researchers publishing in presumed predatory journals: a survey by David Moher, Agnes Grudniewicz, Kelly D Cobey, Manoj M Lalu, Danielle B Rice, Hana Raffoul

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Impact of physician’s sex/gender on processes of care, and clinical outcomes in cardiac operative care: a systematic review by Louise Y Sun, Sylvain Boet, Amy Johnston, Katina Zheng, Mimi Deng, Fadi Mansour, Hussein Said, Cole Etherington

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