Exosomes as Mediators of Cell-to-Cell Communication in Thyroid Disease by Yi Wang, Feng Xu, Jia-Yu Zhong, Xiao Lin, Su-Kang Shan, Bei Guo, Ming-Hui Zheng, Ling-Qing Yuan

“…As a transmitter, exosomes shuttle to different cells or tissues and mediate communications among these organelles. To date, several studies have demonstrated that exosomes play crucial roles in disease pathogenesis and development, such as breast and prostate cancer. …”
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The Role of Galectins as Modulators of Metabolism and Inflammation by Monica Fengsrud Brinchmann, Deepti Manjari Patel, Martin Haugmo Iversen

“…Galectins are found inside cells and in the nucleus, cytosol, and organelles, as well as extracellularly. Galectin-1, -2, -3, -4, -7, -8, -9, and -12 can all induce T-cell apoptosis and modulate inflammation. …”
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Polycystic Diseases in Visceral Organs by Shakila Abdul-Majeed, Surya M. Nauli

“…Primary cilia are nonmotile, microtubule-based, antenna-like organelles projecting from the apical surface of most mammalian cells. …”
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Mitochondrial DNA Damage and Animal Longevity: Insights from Comparative Studies by Reinald Pamplona

“…Mitochondria are a main source of reactive oxygen species (ROS) and chemical sidereactions in healthy aerobic tissues and are the only known extranuclear cellular organelles in animal cells that contain their own DNA (mtDNA). …”
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Tumor-Related Exosomes Contribute to Tumor-Promoting Microenvironment: An Immunological Perspective by Wuzhen Chen, Jingxin Jiang, Wenjie Xia, Jian Huang

“…Exosomes are a kind of cell-released membrane-form structures which contain proteins, lipids, and nucleic acids. These vesicular organelles play a key role in intercellular communication. …”
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Uptake of Photosensitizer 2-Devinyl-2-(1-methoxylethyl) Chlorin f in Human Breast Cancer Cells: A Diffusion Kinetics Study by Ping Chen, Feng Zhang, Lei Zhang, Song-Cheng Mao, Lie Lin, Hua Bai, Guo-Qing Tang, Jian-Zhong Yao, Jun-Hong Yang, Yun-Feng Ma

“…CPD4 permeated into MCF-7 cells with increasing incubation time, which was followed by its binding to cell organelles. Subcellular distribution study revealed that CPD4 was primarily localized on the mitochondria and membranes, supporting that the mode of transmembrane transport was diffusion. …”
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Autophagy: More Than a Nonselective Pathway by Fulvio Reggiori, Masaaki Komatsu, Kim Finley, Anne Simonsen

“…Autophagy is a catabolic pathway conserved among eukaryotes that allows cells to rapidly eliminate large unwanted structures such as aberrant protein aggregates, superfluous or damaged organelles, and invading pathogens. The hallmark of this transport pathway is the sequestration of the cargoes that have to be degraded in the lysosomes by double-membrane vesicles called autophagosomes. …”
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Autophagy in Inflammatory Diseases by Alexander J. S. Choi, Stefan W. Ryter

“…Autophagy provides a mechanism for the turnover of cellular organelles and proteins through a lysosome-dependent degradation pathway. …”
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Generation and study of the synthetic brain electron microscopy dataset for segmentation purpose by N.A. Sokolov, E.P. Vasiliev, A.A. Getmanskaya

“…In this work, we present an algorithm for the synthesis of 6 types of organelles. Based on the EPFL dataset, a training set of 1161 real fragments 256×256 (ORG) and 2000 synthetic ones (SYN), as well as their combination (MIX), were generated. …”
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Germ granule-mediated mRNA storage and translational control by Hoang-Anh Pham-Bui, Mihye Lee

“…These membrane-less organelles form through the condensation of RNA and proteins, governed by multivalent biomolecular interactions. …”
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Ethanolamine-induced assembly of microcompartments is required for Fusobacterium nucleatum virulence by Dana S. Franklin, Yi-Wei Chen, Yimin Chen, Manuel Wittchen, Angela Agnew, Alexis Luu, Julian P. Whitelegge, Z. Hong Zhou, Andreas Tauch, Asis Das, Hung Ton-That

“…ABSTRACT Many bacteria metabolize ethanolamine as a nutrient source through cytoplasmic organelles named bacterial microcompartments (BMCs). …”
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A mouse model of Bardet-Biedl Syndrome has impaired fear memory, which is rescued by lithium treatment. by Thomas K Pak, Calvin S Carter, Qihong Zhang, Sunny C Huang, Charles Searby, Ying Hsu, Rebecca J Taugher, Tim Vogel, Christopher C Cychosz, Rachel Genova, Nina N Moreira, Hanna Stevens, John A Wemmie, Andrew A Pieper, Kai Wang, Kai Wang, Val C Sheffield

“…Primary cilia are microtubule-based organelles present on most cells that regulate many physiological processes, ranging from maintaining energy homeostasis to renal function. …”
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Autophagy-associated signal pathways of functional foods for chronic diseases by Jinfeng Xie, Jiling Liang, Ning Chen

“…Once the cells are in the stress environment, the induced autophagy will accelerate the clearance of cellular damaged or toxic protein aggregates or dysfunctional cellular organelles to maintain homeostasis in cells. In this article, we summarize several widely investigated bioactive components used as functional foods, such as resveratrol, epigallocatechin-3-gallate, curcumin and trehalose, with the regulatory function for autophagy during the intervention of chronic diseases, which will provide the references or novel thoughts for the development of functional foods with the modulation of autophagy. …”
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Mitochondria as a Therapeutic Target: Focusing on Traumatic Brain Injury by Randhall Bruce Carteri

“…Mitochondria are organelles of eukaryotic cells delimited by two membranes and cristae that consume oxygen to produce adenosine triphosphate (ATP), and are involved in the synthesis of vital metabolites, calcium homeostasis, and cell death mechanisms. …”
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Aging, cancer, and autophagy: connections and therapeutic perspectives by Begoña Zapatería, Esperanza Arias, Esperanza Arias

“…While autophagy acts as a tumor-suppressive mechanism by preventing the accumulation of damaged organelles and proteins, cancer cells often exploit it to survive under conditions of metabolic stress and treatment resistance. …”
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Mitochondrial Stress Signalling: HTRA2 and Parkinson's Disease by Enrico Desideri, L. Miguel Martins

“…Mitochondria have a crucial role in supplying energy to the brain, and their deterioration can affect the function and viability of neurons, contributing to neurodegeneration. These organelles can sow the seeds of their own demise because they generate damaging oxygen-free radicals as a byproduct of their intrinsic physiological functions. …”
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The effect of caloric restriction on genetical pathways by Mustafa Fevzi Karagöz, A. Gülçin Sağdıçoğlu Celep

“…The suppression of phosphoinositide 3-kinase (PI3K)-/-Akt, and therefore mTOR signal stimulates autophagy and mitophagia, and cleanses damaged cells and organelles. Mitochondrial biogenesis is stimulated, antioxidant capacity increases, and inflammatory response decreases. …”
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An Unusual Presentation of Desmoplastic Small Round Cell Tumour of the Abdomen: Morphological, Immunohistochemical, Ultrastructural, and Molecular Studies by Preethika Angunawela, Alhossain A. Khalafallah, Karen Wolfswinkel, David Seaton, Terry Brain

“…Electron microscopic examination showed sparse cytoplasmic organelles. The patient succumbed 34 months from disease presentation after multiple chemotherapies and thereafter radiotherapy. …”
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Loss of Kat2b impairs intraflagellar transport and the Hedgehog signaling pathway in primary cilia by Jae Hee Jun, Hwayeon Cha, Je Yeong Ko, Ho-Shik Kim, Kyung Hyun Yoo, Jong Hoon Park

“…Abstract Primary cilia are sensory organelles that regulate various signaling pathways. …”
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Interruption of mitochondrial symbiosis is associated with the development of osteoporosis by Haoling Zhang, Haoling Zhang, Haoling Zhang, Rui Zhao, Xuemei Wang, Yaqian Qi, Doblin Sandai, Wei Wang, Zhijing Song, Zhijing Song, Qiudong Liang

“…Mitochondria maintain bacterial traits because of their endosymbiotic origins, yet the host cell recognizes them as non-threatening since the organelles are compartmentalized. Nevertheless, the controlled release of mitochondrial components into the cytoplasm can initiate cell death, activate innate immunity, and provoke inflammation. …”
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