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Rosiglitazone Induces Mitochondrial Biogenesis in Differentiated Murine 3T3-L1 and C3H/10T1/2 Adipocytes
Published 2011-01-01“…The timing of the increases was consistent with the cascade of organelle biogenesis, that is, initiated by induction of transcription factor(s), followed by increases in the biosynthesis machinery, and then by increases in functional components. …”
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62
Modes and mechanisms for the inheritance of mitochondria and plastids in pathogenic protists.
Published 2025-01-01“…Almost all protists possess mitochondria or mitochondrion-related organelles, and many contain plastids. These endosymbiotic organelles are crucial to survival and provide well-validated and widely utilised drug targets in parasitic protists such as Plasmodium and Toxoplasma. …”
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63
Selective Autophagy in Drosophila
Published 2012-01-01“…Autophagy functions as a cellular response in nutrient starvation, but it is also associated with the removal of protein aggregates and damaged organelles and therefore plays an important role in the quality control of proteins and organelles. …”
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64
Lipophagy: Connecting Autophagy and Lipid Metabolism
Published 2012-01-01“…Lipid droplets (LDs), initially considered “inert” lipid deposits, have gained during the last decade the classification of cytosolic organelles due to their defined composition and the multiplicity of specific cellular functions in which they are involved. …”
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65
Effective anti-adhesives of uropathogenic Escherichia coli
Published 2018-03-01“…Although UPEC may harbour a plethora of virulence factors, type I fimbriae and P pili are two of the most studied adhesive organelles, since the attachment to host cells in the urinary tract is a crucial step towards infection. …”
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66
Ambient fine particulate matter provokes multiple modalities of cell death via perturbation of subcellular structures
Published 2025-01-01“…Although PM2.5 primarily affects the nucleus, cytoskeleton, mitochondria, endoplasmic reticulum, and lysosomes, other organelles like ribosomes, Golgi apparatus, and peroxisomes have received limited attention. …”
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67
Artificial cells with all-aqueous droplet-in-droplet structures for spatially separated transcription and translation
Published 2025-01-01“…This approach provides a practical tool for exploring complex systems of artificial organelles within large ensembles of artificial cells.…”
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68
Crotalus durissus ruruima Snake Venom and a Phospholipase A2 Isolated from This Venom Elicit Macrophages to Form Lipid Droplets and Synthesize Inflammatory Lipid Mediators
Published 2019-01-01“…Moreover, PGE2 colocalized to CdrV- and CBr-induced LDs, revealing the role of these organelles as sites for the synthesis of prostanoids. …”
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69
Mitochondrial abnormalities as a target of intervention in acute myeloid leukemia
Published 2025-01-01“…On one hand, it provides a source of building blocks for further cell division and serves as a method for removing damaged organelles, promoting cell survival. However, the profound metabolic changes to mitochondria also render these organelles more sensitive to damage and place them precariously close to excess mitophagic activation. …”
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70
Mitochondrial Dysfunction: A Basic Mechanism in Inflammation-Related Non-Communicable Diseases and Therapeutic Opportunities
Published 2013-01-01“…These organelles act to supply the cell with ATP and to synthesise key molecules in the processes of inflammation, oxidation, and metabolism. …”
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71
Lithium Improves Survival of PC12 Pheochromocytoma Cells in High-Density Cultures and after Exposure to Toxic Compounds
Published 2014-01-01“…Autophagy is an evolutionary conserved mechanism that allows for the degradation of long-lived proteins and entire organelles which are driven to lysosomes for digestion. …”
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72
Cellular electron tomography of the apical complex in the apicomplexan parasite Eimeria tenella shows a highly organised gateway for regulated secretion.
Published 2022-07-01“…The apical complex of apicomplexan parasites is essential for host cell invasion and intracellular survival and as the site of regulated exocytosis from specialised secretory organelles called rhoptries and micronemes. Despite its importance, there are few data on the three-dimensional organisation and quantification of these organelles within the apical complex or how they are trafficked to this specialised region of plasma membrane for exocytosis. …”
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73
Biochemical characterization of the Escherichia coli surfaceome: a focus on type I fimbriae and flagella
Published 2025-02-01“…The Escherichia coli surfaceome consists mainly of the large surface organelles expressed by the organism to navigate and interact with the surrounding environment. …”
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74
Alternative Macroautophagic Pathways
Published 2012-01-01“…Macroautophagy is a bulk degradation process that mediates the clearance of long-lived proteins, aggregates, or even whole organelles. This process includes the formation of autophagosomes, double-membrane structures responsible for delivering cargo to lysosomes for degradation. …”
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75
Powering the Immune System: Mitochondria in Immune Function and Deficiency
Published 2014-01-01“…Mitochondria are critical subcellular organelles that are required for several metabolic processes, including oxidative phosphorylation, as well as signaling and tissue-specific processes. …”
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76
Yeast Methylotrophy: Metabolism, Gene Regulation and Peroxisome Homeostasis
Published 2011-01-01“…When these yeasts are grown on methanol as the sole carbon and energy source, the enzymes involved in methanol metabolism are strongly induced, and the membrane-bound organelles, peroxisomes, which contain key enzymes of methanol metabolism, proliferate massively. …”
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77
Podocyte Autophagy: A Potential Therapeutic Target to Prevent the Progression of Diabetic Nephropathy
Published 2017-01-01“…Autophagy is a high conserved cellular process in lysosomes including impaired protein, cell organelles, and other contents in the cytoplasm. Recent studies suggest that activation of autophagy in podocytes may be a potential therapy to prevent the progression of DN. …”
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78
Mitochondrial Dynamics: In Cell Reprogramming as It Is in Cancer
Published 2017-01-01“…Somatic cells transform their tubular and interconnected mitochondrial network to the fragmented and isolated organelles found in pluripotent stem cells early during cell reprogramming. …”
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79
A review of the pathogenesis of mitochondria in breast cancer and progress of targeting mitochondria for breast cancer treatment
Published 2025-01-01“…Mitochondria, highly dynamic intracellular organelles, play a pivotal role in maintaining cellular energy metabolism. …”
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The Emerging Role of Proteolysis in Mitochondrial Quality Control and the Etiology of Parkinson’s Disease
Published 2012-01-01“…Mitochondria are highly dynamic organelles that are important for many diverse cellular processes, such as energy metabolism, calcium buffering, and apoptosis. …”
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