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Identification of Pentatricopeptide Repeat Proteins in the Model Organism Dictyostelium discoideum
Published 2013-01-01“…Pentatricopeptide repeat (PPR) proteins are RNA binding proteins with functions in organelle RNA metabolism. They are found in all eukaryotes but have been most extensively studied in plants. …”
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22
The Golgi in Cell Migration: Regulation by Signal Transduction and Its Implications for Cancer Cell Metastasis
Published 2012-01-01“…The Golgi apparatus, an organelle involved in posttranslational modification and sorting of proteins, is widely accepted to regulate directional cell migration. …”
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23
The Role of Mitochondria from Mature Oocyte to Viable Blastocyst
Published 2013-01-01“…With a better understanding of the role of this organelle in oocytes immediately after fertilization, blastocyst and offspring, mitochondrial augmentation may be reconsidered as a method to improve oocyte quality.…”
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24
Autophagy-lysosome pathway in insulin & glucagon homeostasis
Published 2025-02-01“…Lysosome, a highly dynamic organelle, is an important nutrient sensing center. …”
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25
RNA Viruses: ROS-Mediated Cell Death
Published 2014-01-01“…Moreover, ROS may play an important role as a signal molecule in the regulation of viral replication and organelle function, potentially providing new insights in the prevention and treatment of RNA viruses and retrovirus infections.…”
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26
Cell migration in dense microenvironments
Published 2023-09-01“…However, increasing evidence shows that the nucleus is an active organelle, constantly sensing the surrounding environment and translating extracellular mechanical inputs into intracellular signaling. …”
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27
Chemigenetic Ca2+ indicators report elevated Ca2+ levels in endothelial Weibel-Palade bodies.
Published 2025-01-01“…Weibel-Palade bodies (WPB) are secretory organelles exclusively found in endothelial cells and among other cargo proteins, contain the hemostatic von-Willebrand factor (VWF). …”
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28
Introducing carbon assimilation in yeasts using photosynthetic directed endosymbiosis
Published 2024-07-01“…We anticipate that our studies will have significant implications for sustainable biotechnology, synthetic biology, and experimentally studying the evolutionary adaptation of an additional organelle in yeast.…”
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Engineering artificial photosynthetic life-forms through endosymbiosis
Published 2022-04-01“…We anticipate that these genetically tractable endosymbiotic platforms can be used for evolutionary studies, particularly related to organelle evolution, and also for synthetic biology applications.…”
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30
Interspecific incompatibility in wide hybridization of plants and ways to overcome
Published 2016-09-01“…Development of alloplasmatic lines is connected with structural and functional variability of nuclear and organelle genomes.…”
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31
Human Mesenchymal Stem Cells: The Present Alternative for High-Incidence Diseases, Even SARS-Cov-2
Published 2020-01-01“…Mesenchymal stem cells (MSCs), defined as plastic adherent cells with multipotent differentiation capacity in vitro, are an emerging and valuable tool to treat a plethora of diseases due to their therapeutic mechanisms such as their paracrine activity, mitochondrial and organelle transfer, and transfer of therapeutic molecules via exosomes. …”
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32
First report of the chloroplast and mitochondrial genomes of the Indian pitcher plant, Nepenthes khasiana Hook.f.
Published 2025-01-01“…Herein, we report the complete chloroplast (cp) and mitochondrial (mt) genomes of N. khasiana for the first time. These organelle genomes were assembled as part of a whole-genome sequencing project aimed at gaining deeper insights into their evolutionary relations with genomes of other carnivorous plants. …”
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Single-cell atlas reveals multi-faced responses of losartan on tubular mitochondria in diabetic kidney disease
Published 2025-01-01“…Conclusions Our research suggests that scRNA-seq can reflect the multifaceted mitochondrial landscape of DKD renal tubular cells after drug treatment, and these findings may provide new targets for DKD therapy at the organelle level.…”
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Association of a BACE1 Gene Polymorphism with Parkinson’s Disease in a Norwegian Population
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Complete Sequence and Characterization of Mitochondrial and Chloroplast Genome of <i>Navicula incerta</i> CACC 0356
Published 2025-01-01“…However, the scarcity of organelle genome data within the Navicula clade has impeded a comprehensive understanding and utilization of this group. …”
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Endoplasmic Reticulum Stress: Its Role in Disease and Novel Prospects for Therapy
Published 2012-01-01“…The endoplasmic reticulum (ER) is a multifunctional organelle required for lipid biosynthesis, calcium storage, and protein folding and processing. …”
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Tissue-Related Hypoxia Attenuates Proinflammatory Effects of Allogeneic PBMCs on Adipose-Derived Stromal Cells In Vitro
Published 2016-01-01“…Under O2 ASCs retained their proliferative and differentiative capacities, mesenchymal phenotype, and intracellular organelle’ state. ASCs were proinflammatory activated on transcription level that was confirmed by their ability to suppress activation and proliferation of mitogen-stimulated PBMCs. …”
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Intracellular Membrane Contact Sites in Skeletal Muscle Cells
Published 2025-01-01“…Intracellular organelles are common to eukaryotic cells and provide physical support for the assembly of specialized compartments. …”
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Endoplasmic Reticulum Stress in Systemic Lupus Erythematosus and Lupus Nephritis: Potential Therapeutic Target
Published 2023-01-01“…The endoplasmic reticulum (ER) is the largest intracellular organelle and is a site of protein synthesis, lipid metabolism, and calcium storage. …”
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The Role of Autophagy in the Pathogenesis of Diabetic Nephropathy
Published 2013-01-01“…Autophagy is a catabolic process that degrades damaged proteins and organelles in mammalian cells and plays a critical role in maintaining cellular homeostasis. …”
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