Role of the Notch signaling pathway in porcine oocyte maturation by Pil-Soo Jeong, Hyo-Gu Kang, Dabin Cha, Se-Been Jeon, Min Ju Kim, Bong-Seok Song, Bo-Woong Sim, Sanghoon Lee

“…Furthermore, RO significantly impaired the cellular distribution and functions of the mitochondria and endoplasmic reticula, which are important organelles for the cytoplasmic maturation of oocytes. …”
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The Effect of A2E on the Uptake and Release of Calcium in the Lysosomes and Mitochondria of Human RPE Cells Exposed to Blue Light by Mao-Mei Luo, Lin Chen, Shu Wang, Chun Zeng, De-Zhi Li, YeGe Bi, Long-Qian Liu, Shan-Jun Cai

“…In order to measure the calcium levels in the different organelles, RPE were imaged using a laser scanning confocal microscope. …”
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The regulatory role of cystatin C in autophagy and neurodegeneration by T. A. Korolenko, A. B. Shintyapina, A. B. Pupyshev, A. A. Akopyan, G. S. Russkikh, M. A. Dikovskaya, V. A. Vavilin, E. L Zavjalov, M. A. Tikhonova, T. G. Amstislavskaya

“…Autophagy is a dynamic cellular process involved in the turnover of proteins, protein complexes, and organelles through lysosomal degradation. It is particularly important in neurons, which do not have a proliferative option for cellular repair. …”
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The Role of Autophagy in Copper-Induced Apoptosis and Developmental Neurotoxicity in SH-SY5Y Cells by Lu Lu, Ying Zhang, Wei Shi, Qian Zhou, Zhuoqi Lai, Yuepu Pu, Lihong Yin

“…Neurons are nonrenewable, and they are unable to mitigate the excessive accumulation of pathological proteins and organelles in cells, which can be ameliorated by autophagic degradation. …”
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Genome-wide identification of the Sec14 gene family and the response to salt and drought stress in soybean (Glycine max) by Jinyu Zhang, Liying Zou, Li Wang, Dongchao Zhang, Ao Shen, Yongqi Lei, Maoni Chao, Xinjuan Xu, Zhiwei Xue, Zhongwen Huang

“…Abstract Background The Sec14 domain is an ancient lipid-binding domain that evolved from yeast Sec14p and performs complex lipid-mediated regulatory functions in subcellular organelles and intracellular traffic. The Sec14 family is characterized by a highly conserved Sec14 domain, and is ubiquitously expressed in all eukaryotic cells and has diverse functions. …”
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Related Pentacyclic Triterpenes Have Immunomodulatory Activity in Chronic Experimental Visceral Leishmaniasis by Jéssica Adriana de Jesus, Márcia Dalastra Laurenti, Leila Antonangelo, Caroline Silvério Faria, João Henrique Ghilardi Lago, Luiz Felipe Domingues Passero

“…Thus, the aim of the present study was to compare the in vitro antileishmanial activity of the triterpenes betulin (Be), lupeol (Lu), and ursolic acid (UA); analyze the physiology and morphology of affected organelles; analyze the toxicity of selected triterpenes in golden hamsters; and study the therapeutic activity of triterpenes in hamsters infected with L. …”
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The influence of exogenous recombinant HSP 70 on the alteration of membrane stiffness in hippocampal neurons following the modeling of neonatal hypoxic-ischemic injury in mice Auth... by Vladimir M. Pokrovsky, Alexey V. Deikin, T Zhang, Nikolai A. Verlov, Andrey L. Konevega, Mikhail V. Korokin

“…Heat shock protein HSP 70, a component of the cellular stress response system, plays a role in stabilizing the protein structures of cellular organelles. However, studies examining changes in the stiffness of hippocampal neuronal membranes in its presence, particularly following cerebral circulation disturbances, have not been conducted yet. …”
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Electroacupuncture Relieves Suppression of Autophagy in Interstitial Cells of Cajal of Diabetic Gastroparesis Rats by Xing Wei, Yaping Lin, Dongfeng Zhao, Xiaojuan Xiao, Qiao Chen, Siyi Chen, Yan Peng

“…Autophagy could degrade damaged proteins and organelles to keep intracellular homeostasis, and it could directly influence structure and number of cells. …”
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Angiogenesis Regulated by Electroacupuncture Combined with Rehabilitation Training in Cerebral Ischemia Involved in PI3K/Akt Signaling Pathway by Wenchao YAO, Mengxing LI, Qing LIU, Mingyue TONG, Peng HE, Wei TANG

“…The relative expression levels of vascular endothelial growth factor (VEGF), brain-derived neurotrophic factor (BDNF), PI3K and Akt were detected by Western blot and RT-PCR respectively.Results:(1) The neurons in the ischemic area of the model group were irregular in morphology, vacuolation, reduction of glycosomes and autophagic vesicles in the cytoplasm, swelling of mitochondria and pyknosis of nucleus; Compared with the model group, on day 3, 7 and 14 of treatment, the neuron cell membrane of the combined acupuncture group showed a tendency to repair, and the structure of organelles and the degree of vacuolation were significantly improved.(2) On day 3, 7 and 14 of treatment, the MVD count of cerebral ischemia area was statistically significant in different groups (<italic>F</italic>_Intergroup=141.762, <italic>P</italic>&lt; 0.001), the MVD count of the combined acupuncture group was higher than that of the other two groups, the difference was statistically significant respectively (<italic>P</italic>&lt; 0.01); On day 3, 7 and 14 of treatment, there was significant difference in the change trend of different time points respectively (<italic>F</italic>_Time=81.920, <italic>P</italic>&lt; 0.001), the combined acupuncture group increased significantly on the 14th day of treatment, and the differences were statistically significant (<italic>P</italic>&lt; 0.01); MVD count had group×time obvious interaction (<italic>F</italic>_Interaction=44.960, <italic>P</italic>&lt; 0.001). (3) The variance analysis of repeated measurements of VEGF, BDNF, PI3K, Akt proteins in the brain tissue of the ischemic area showed that the variables were statistically significant among different groups respectively (<italic>F</italic>_Intergroup=398.772, 903.082, 2 312.264, and 1 581.880, <italic>P</italic>&lt; 0.001). …”
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