Radiological, Clinical, and Histological Findings in the Treatment of Pilonidal Sinus with Phenol Injection by Tonguc Utku YILMAZ, Omer YAVUZ, Ahmet Oktay YIRMIBESOGLU, Hasan Tahsin SARISOY, Cigdem VURAL, Umay KIRAZ, Nihat Zafer UTKAN

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Impact of New-Onset Diabetes after Transplantation on Cardiovascular Risk and Mortality in Korea: A Nationwide Population-Based Study by Seung Shin Park, Bo Kyung Koo, Sanghyun Park, Kyungdo Han, Min Kyong Moon

“…Background Limited data are available on the adverse effects of new-onset diabetes after transplantation (NODAT) in solid organ transplantation (TPL) other than kidney. This study aimed to identify the risk of complications associated with NODAT in recipients of kidney, liver, or heart TPL. …”
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Mycophenolate mofetil: an update on its mechanism of action and effect on lymphoid tissue by Anna Krawczyk, Bernard Kravčenia, Tomasz Maślanka

“…IntroductionMycophenolate mofetil (MMF) is an immunosuppressive drug administered in the management of both autoimmune diseases and organ transplantation. The main aims of the study were: (a) to obtain information regarding the safety of using MMF in respect of its effect on normal T and B cells in lymphoid tissues; (b) to investigate whether the generation of inducible Foxp3-expressing regulatory T cells (Treg) might constitute additional mechanisms underlying the immunosuppressive properties of MMF.MethodsThe effect of MMF (in vivo studies) and its active metabolite, mycophenolic acid, (in vitro studies) on murine CD4+ and CD8+ T cells as well as B cells was determined, regarding: (a) absolute count, proliferation and apoptosis of these cells (in vitro studies); (b) absolute count of these cells in the head and neck lymph nodes, mesenteric lymph nodes and the spleen (in vivo studies).ResultsThe study found that the treatment of mice with MMF induced depletion of CD4+ and CD8+ T cells and B cells in lymph nodes and the spleen, and the magnitude of these effects should be considered as clinically relevant. …”
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Development and Evaluation of a Novel Radiotracer 125I-rIL-27 to Monitor Allotransplant Rejection by Specifically Targeting IL-27Rα by Shanshan Zhao, Qian Liu, Feng Gao, Guihua Hou

“…Noninvasive monitoring of allograft rejection is beneficial for the prognosis of patients with organ transplantation. Recently, IL-27/IL-27Rα was proved in close relation with inflammatory diseases, and 125I-anti-IL-27Rα mAb our group developed demonstrated high accumulation in the rejection of the allograft. …”
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New Dimensional Staging of Bisphosphonate-Related Osteonecrosis of the Jaw Allowing a Guided Surgical Treatment Protocol: Long-Term Follow-Up of 266 Lesions in Neoplastic and Oste... by Simonetta Franco, Simona Miccoli, Luisa Limongelli, Angela Tempesta, Giorgio Favia, Eugenio Maiorano, Gianfranco Favia

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Protracted Hypocalcemia following 3.5 Parathyroidectomy in a Kidney Pancreas Recipient with a History of Robotic-Assisted Roux-en-Y Gastric Bypass by Hugo Bonatti, Naureen Iqbal, Catherine Kling, Willie Melvin, James Broome

“…Alternative bariatric procedures such as sleeve gastrectomy may be more suitable for patients with renal failure or organ transplants in whom adequate absorption of vitamins, minerals, and drugs such as immunosuppressants is essential.…”
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Diffusion MRI Findings in Encephalopathy Induced by Immunosuppressive Therapy after Liver Transplantation by Emanuele Tinelli, Nicoletta Locuratolo, Alberto Pierallini, Massimo Rossi, Francesco Fattapposta

“…The introduction of calcineurin inhibitors, cyclosporine A and tacrolimus, in immunosuppressive regimens significantly improved the outcome of solid-organ transplantation even though immunosuppression-associated neurotoxicity remains a significant complication, particularly occurring in about 25% of cases after liver transplantation. …”
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Therapeutic drug monitoring for triazoles: A needs assessment review and recommendations from a Canadian perspective by Michel Laverdiere, Eric J Bow, Coleman Rotstein, Julie Autmizguine, Raewyn Broady, Gary Garber, Shariq Haider, Trana Hussaini, Shahid Husain, Philippe Ovetchkine, Jack T Seki, Yves Théorêt

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Molecular Xenomonitoring (MX) allows real-time surveillance of West Nile and Usutu virus in mosquito populations. by Clément Bigeard, Laura Pezzi, Raphaelle Klitting, Nazli Ayhan, Grégory L'Ambert, Nicolas Gomez, Géraldine Piorkowski, Rayane Amaral, Guillaume André Durand, Agathe M G Colmant, Cynthia Giraud, Katia Ramiara, Camille Migné, Gilda Grard, Thierry Touzet, Stéphan Zientara, Rémi Charrel, Gaëlle Gonzalez, Alexandre Duvignaud, Denis Malvy, Xavier de Lamballerie, Albin Fontaine

“…Notably, WNV can also be transmitted through blood donations and organ transplants. The high proportion of asymptomatic infections caused by these viruses and their cryptic enzootic circulation make their early detection in the environment challenging. …”
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Multiple rare abdominal aortic branch variations in the case of a centenarian woman. Case report and review of the literature by Michela Vincis, Claire Lewis, Denis Barry, Marcello Trucas

“…Background: Anatomical variations of the abdominal aorta are crucial when considering the success of clinical procedures including diagnostic imaging, oncologic resections, organ transplantations, laparoscopic surgeries, management of penetrating abdominal injuries, and interventional radiological procedures. …”
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Decision-making behavior of blood glucose management and its influencing factors in pregnant women with gestational diabetes mellitus by Shuai Xu, Jing Wang, Yan Wang, Dawei Wang, Meng Zhang

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Chronic hepatitis B and risk of kidney involvement by M. V. Mayevskaya, I. N. Tikhonov, V. T. Ivashkin

“…Antiviral therapy is indicated to the most of these patients which potential, at the same time, is limited by initially decreased renal function, nephrotoxicity of some drugs or simultaneous prescription of immunosuppressants after organ transplantation. At development of liver cirrhosis (LC) and its decompensation one more aspect of renal disease at CHB arises i.e. risk of hepatorenal syndrome (HRS) of the 1st or 2nd type that is a poor prognostic marker and requires individual therapeutic approach.Conclusion. …”
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Management of Instrument Sterilization Workflow in Endodontics: A Systematic Review and Meta-Analysis by Mario Dioguardi, Diego Sovereto, Gaetano Illuzzi, Enrica Laneve, Bruna Raddato, Claudia Arena, Vito Carlo Alberto Caponio, Giorgia Apollonia Caloro, Khrystyna Zhurakivska, Giuseppe Troiano, Lorenzo Lo Muzio

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Bone Regeneration Induced by Bone Porcine Block with Bone Marrow Stromal Stem Cells in a Minipig Model of Mandibular “Critical Size” Defect by Antonio Scarano, Vito Crincoli, Adriana Di Benedetto, Valerio Cozzolino, Felice Lorusso, Michele Podaliri Vulpiani, Maria Grano, Zamira Kalemaj, Giorgio Mori, Felice Roberto Grassi

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Study of antifungal susceptibility pattern of various Candida species with reference to conventional and automated methods in a tertiary care hospital by Paulami De, Rehena Sarkar, Raja Ray, Kumkum Bhattacharyya, Hasina Banu, Hirak Jyoti Raj

“…Conclusion: The increasing incidence of HIV infections, increasing incidence of organ transplantation, wide spread use of antibiotics and use of immunosuppressive agents are the important causative factors responsible for the increasing incidence of Candida infections. …”
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Advancements in noninvasive techniques for transplant rejection: from biomarker detection to molecular imaging by Yuan Song, Yihui Wang, Wenyuan Wang, Yuji Xie, Junmin Zhang, Jing Liu, Qiaofeng Jin, Wenqian Wu, He Li, Jing Wang, Li Zhang, Yali Yang, Tang Gao, Mingxing Xie

“…Abstract Transplant rejection remains a significant barrier to the long-term success of organ transplantation. Biopsy, although considered the gold standard, is invasive, costly, and unsuitable for routine monitoring. …”
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Attitudes of polish medical students toward organ donation by Marzena Mikla, Anna Maria Cybulska, Antonio Rios, Mariusz Panczyk, Kamila Rachubińska, Artur Kotwas, Beata Karakiewicz, Elżbieta Grochans, Daria Schneider-Matyka

“…It was performed using a validated questionnaire of attitude toward organ donation and transplantation (ODT) [PCID-DTO RIOS: A questionnaire designed by the International Collaborative Organ Donation project about organ transplantation and donation].ResultsIt was shown that those who would not donate their family member’s organs for transplantation were far more likely to believe it was not their moral duty (p = 0.013) and to feel no solidarity with those in need (p = 0.000). …”
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The Promising Effect of Tocilizumab on Chronic Antibody-Mediated Rejection (cAMR) of Kidney Transplant by Łukasz Świątek, Miłosz Miedziaszczyk, Dominik Lewandowski, Filip Robakowski, Piotr Tyburski, Marta Jakubowska, Marek Karczewski, Ilona Idasiak-Piechocka

“…<b>Background</b>: Chronic antibody-mediated rejection (cAMR) constitutes a serious challenge in the long-term success of organ transplantation. It is associated with donor-specific antibodies (DSAs) which activate a complement pathway in response to the presence of human leukocyte antigens (HLAs) on the graft, which results in chronic inflammation and leads to graft dysfunction. …”
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Tubular MYDGF Slows Progression of Chronic Kidney Disease by Maintaining Mitochondrial Homeostasis by Xiaohan Liu, Yang Zhang, Youzhao Wang, Yujie Yang, Zhe Qiao, Ping Zhan, Huiying Jin, Qianqian Xu, Wei Tang, Yu Sun, Yan Zhang, Fan Yi, Min Liu

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Low regulatory T-cells frequency is associated with graft rejection after small bowel transplantation: Clinical and experimental evidence. by Rodrigo Papa-Gobbi, Pablo Stringa, Maria Virginia Gentilini, Ivana Ivanoff, Mariana Machuca, Nidia Monserrat Arreola, Javier Serradilla, Karla Estefanía-Fernández, Paloma Talayero, María Velayos, Elena Sánchez-Zapardiel, Gabriel Gondolesi, Ane Andrés-Moreno, Martin Rumbo, Francisco Hernández-Oliveros

“…Nevertheless, its rejection rate surpasses that of other solid organ transplants due to the heightened immunological load of the gut. …”
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