Comparison of User-Directed and Automatic Mapping of the Planned Isocenter to Treatment Space for Prostate IGRT by Zijie Xu, Ronald Chen, Andrew Wang, Andrea Kress, Mark Foskey, An Qin, Timothy Cullip, Gregg Tracton, Sha Chang, Joel Tepper, Di Yan, Edward Chaney

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Metronomic Cyclophosphamide and Methotrexate Chemotherapy Combined with 1E10 Anti-Idiotype Vaccine in Metastatic Breast Cancer by Jorge L. Soriano, Noyde Batista, Eduardo Santiesteban, Mayté Lima, Joaquín González, Robin García, Yohanka Zarza, María V. López, Myriam Rodríguez, Jorge L. Loys, Narciso Montejo, Frank Aguirre, Amparo Macías, Ana M. Vázquez

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Hypofractionated radiotherapy combined with a PD-1 inhibitor, granulocyte macrophage-colony stimulating factor, and thymosin-α1 in advanced metastatic solid tumors: a multicenter P... by Jiamin Yu, Li Yin, Wenjie Guo, Qiang Wang, Juying Liu, Lansheng Zhang, Hongxun Ye, Jianhong Xia, Youyou Xia, Jianfeng Wu, Wanwei Wang, Yanguang Yang, Dan Zong, Xia He, Lijun Wang, Hong Jiang

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Concomitant exposure to benzodiazepines during pembrolizumab-based therapy for advanced non-small-cell lung cancer: a propensity-score matched analysis of monitoring agency data by Fabrizio Nelli, Enzo Maria Ruggeri, Antonella Virtuoso, Diana Giannarelli, Armando Raso, Federica Natoni, Gloria Pessina, Daniele Remotti, Mario Giovanni Chilelli, Carlo Signorelli, Agnese Fabbri

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Inhibition of growth of colorectal cancer patient-derived subcutaneous xenografts using combined Wnt signaling pathway inhibitor and 5‑fluorouracil by A. S. Goncharova, A. V. Galina, D. V. Khodakova, G. Yu. Egorov, A. Yu. Maksimov, E. N. Kolesnikov, E. F. Komarova, A. A. Kiblitskaya, E. V. Zaikina, L. Z. Kurbanova, M. V. Mindar

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Germline Human Leukocyte Antigen Status is Associated With Immunotherapy-Induced Pneumonitis and Treatment Response in Patients With Non–Small Cell Lung Cancer With High Programmed... by Alvin H.K. Cheung, MBBS, PhD, Zeta Mui, MPhil, Walter W. Yeung, PhD, Chit Chow, PhD, Mandy F. Yu, BSc, Olivia H. Chen, MD, PhD, Kit-Yee Wong, MPhil, Fuda Xie, MPhil, Yat Ming Lau, MBBS, Alfred S-L. Cheng, PhD, Wei Kang, PhD, Ka-Fai To, MBChB, Tony S. Mok, MD, Molly S.C. Li, MBBS

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Diagnosis and Treatment of Rheumatic Adverse Events Related to Immune Checkpoint Inhibitors by Yan Xiao, Lin Zeng, Qinglin Shen, Zhiyong Zhou, Zhifang Mao, Qin Wang, Xiquan Zhang, Yingliang Li, Weirong Yao

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Metformin Ameliorates D-Galactose-Induced Senescent Human Bone Marrow-Derived Mesenchymal Stem Cells by Enhancing Autophagy by Pingting Ye, Lei Feng, Dan Zhang, Ruihao Li, Yixuan Wen, Xiaohan Tong, Shuo Shi, Chunyan Dong

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Experimental approach to obtaining subcutaneous xenograft of non-small cell lung cancer by E. A. Lukbanova, M. V. Mindar, E. A. Dzhenkova, A. Yu. Maksimov, A. S. Goncharova, Yu. S. Shatova, A. A. Maslov, A. V. Shaposhnikov, E. V. Zaikina, Yu. N. Lazutin

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Functional-proteomics-based investigation of the cellular response to farnesyltransferase inhibition in lung cancer by Yanbo Pan, Olena Berkovska, Soumitra Marathe, Georgios Mermelekas, Greta Gudoityte, Amare D. Wolide, Taner Arslan, Brinton Seashore-Ludlow, Janne Lehtiö, Lukas M. Orre

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Blood-based prognostic scores and early dynamics under immunotherapy to select patients with metastatic solid tumors for continuing immune check-point inhibition: a prospective lon... by Javier García-Corbacho, Alberto Indacochea, Iván Victoria, Débora Moreno, Laura Angelats, Azucena E. González Navarro, Laura Mezquita, Fara Brasó-Maristany, Patricia Galván, Begoña Mellado, Nuria Viñolas, Tamara Sauri, Miquel Nogué, Barbara Adamo, Joan Maurel, Estela Pineda, Lydia Gaba, Oscar Reig, Neus Basté, Esther Sanfeliu, Manel Juan, Aleix Prat, Francesco Schettini

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Association of immune-related adverse events with the outcomes of immune checkpoint inhibitors in patients with dMMR/MSI-H metastatic colorectal cancer by Chiara Cremolini, Sara Lonardi, Filippo Pietrantonio, Francesca Corti, Elisabetta Fenocchio, Massimiliano Salati, Margherita Ambrosini, Michael J Overman, Lisa Salvatore, Rossana Intini, Priya Jayachandran, Javier Ros, Maria Elena Elez, Marwan Fakih, Aakash Tushar Shah, Rosalba Miceli, Monica Niger, Vincenzo Nasca, Giacomo Mazzoli, Francesco Barretta

“…Based on the results retrieved from organ-specific irAEs, ‘aggregated’ burden scores were developed to distinguish ‘protective’ (endocrine and musculoskeletal) and ‘harmful’ (gastrointestinal, pneumonitis, neurological, hepatic) irAEs showing prognostic effects on OS and PFS.Conclusions Our results demonstrate that not all irAEs could exert a protective effect on oncologic outcome. An easy-to-use model for ICIs toxicity (burden score of protective and harmful irAEs) may be used as surrogate marker of response.…”
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FBXO31-mediated ubiquitination of OGT maintains O-GlcNAcylation homeostasis to restrain endometrial malignancy by Na Zhang, Yang Meng, Song Mao, Huiling Ni, Canhua Huang, Licong Shen, Kun Fu, Lu Lv, Chunhong Yu, Piyanat Meekrathok, Chunmei Kuang, Fang Chen, Yu Zhang, Kai Yuan

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Divergent response to radio-immunotherapy is defined by intrinsic features of the tumor microenvironment by Christian Klein, Maria Amann, Jacob Gadwa, Laurel B Darragh, Miles Piper, Diemmy Nguyen, Sana D Karam, Michael W Knitz, Justin Yu, Nicholas Olimpo, Sophia Corbo, Jessica I Beynor, Brooke Neupert, Alexander T Nguyen, Chloe Hodgson, Khalid NM Abdelazeem, Anthony Saviola, Laurene Pousse, Ali Bransi, Mudita Pincha

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Exosomal miR-543 Inhibits the Proliferation of Ovarian Cancer by Targeting IGF2 by Shupei Zhang, Diling Pan, Shaoyu Zhang, Qiumei Wu, Lan Zhen, Shihuang Liu, Jingjing Chen, Rong Lin, Qiuhua Hong, Xiangqin Zheng, Huan Yi

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A Case of In-Bore Transperineal MRI-Guided Prostate Biopsy of a Patient with Ileal Pouch-Anal Anastomosis by Michael Kongnyuy, Thomas Frye, Arvin K. George, Amichai Kilchevsky, Amogh Iyer, Meet Kadakia, Akhil Muthigi, Baris Turkbey, Brad J. Wood, Peter A. Pinto

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Corrigendum to “PIPKIγ Regulates CCL2 Expression in Colorectal Cancer by Activating AKT-STAT3 Signaling” by JunLi Xue, XiaoXiao Ge, Wei Zhao, Liqiong Xue, Congqi Dai, Fengjuan Lin, Wei Peng

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Corrigendum to “Acute Lymphoblastic Leukemia following Lenalidomide Maintenance for Multiple Myeloma: Two Cases with Unexpected Presentation and Good Prognostic Features” by Abdullah M. Khan, Jameel Muzaffar, Hemant Murthy, John R. Wingard, Jan S. Moreb

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Development and validation of predictive models of early immune effector cell–associated hematotoxicity by Emily C. Liang, Jennifer J. Huang, Andrew J. Portuguese, Valentín Ortiz-Maldonado, Aya Albittar, Natalie Wuliji, Ryan Basom, Yein Jeon, Qian Wu, Aiko Torkelson, Delaney Kirchmeier, Abigail Chutnik, Barbara Pender, Mohamed Sorror, Joshua A. Hill, Noam E. Kopmar, Rahul Banerjee, Andrew J. Cowan, Damian Green, Ajay K. Gopal, Christina Poh, Mazyar Shadman, Alexandre V. Hirayama, Brian G. Till, Erik L. Kimble, Lorenzo Iovino, Aude G. Chapuis, Folashade Otegbeye, Ryan D. Cassaday, Filippo Milano, Cameron J. Turtle, David G. Maloney, Jordan Gauthier

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Role of hypothalamic-pituitary-adrenal axis and catecholamine factors in independent and primary multiple types of tumor growth by E. M. Frantsiyants, V. A. Bandovkina, I. V. Kaplieva, E. I. Surikova, Yu. A. Pogorelova, N. D. Cheryarina, L. K. Trepitaki, I. V. Neskubina, A. A. Vereskunova, I. M. Kotieva, K. A. Shumarin, A. I. Shikhlyarova, I. V. Goroshinskaya

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