Genetic Background Strongly Influences the Bone Phenotype of P2X7 Receptor Knockout Mice by Susanne Syberg, Solveig Petersen, Jens-Erik Beck Jensen, Alison Gartland, Jenni Teilmann, Iain Chessell, Thomas H. Steinberg, Peter Schwarz, Niklas Rye Jørgensen

“…In this study we investigated the importance of the genetic background of the mouse strains on which the P2X7 knock-out models were based by comparing bone status of a new BALB/cJ P2X7−/− strain with a previous one based on the C57BL/6 strain. Female four-month-old mice from both strains were DXA scanned on a PIXImus densitometer; femurs were collected for bone strength measurements and serum for bone marker analysis. …”
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The Relevance of the Virchow Node and Virchow Triad in Renal Cancer Diagnosis by Luiza-Roxana Dorobantu-Lungu, Viviana Dinca, Andrei Gegiu, Dan Spataru, Andreea Toma, Luminita Welt, Mihaela Florentina Badea, Constantin Caruntu, Cristian Scheau, Ilinca Savulescu-Fiedler

“…<b>Methods:</b> We present a case of a 66-year-old man with Virchow–Troisier adenopathy during physical examination, which raises the suspicion of infra-diaphragmatic tumor. …”
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The impact of educational intervention based on the theory of planned behavior on preventive behaviors for gastric cancer in obese and smoking individuals by Siamak Najafi, Fatemeh Mohammadkhah, Saina Alempour Salemi, Amirhossein Kamyab, Ali Khani Jeihooni

“…Methods This quasi-experimental study was conducted in 2021–2022 on 150 obese or overweight individuals, more than 25 years old who smoked (cigarettes and hookah) in Fasa city, Iran. …”
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Prevalence of Pulmonary Embolism in COVID-19 Positive Critically Ill Children by Yudy Fonseca, MD, Alise Davies, PA, Stephanie Jarrin, MD, Liliana Simon, MD, Cortney Foster, DO, Sun Kai, Adnan Bhutta, MD

“…Patients 28 days to younger than 18 years old, admitted to a PICU with either PE or COVID-19 diagnoses. …”
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Synergistic effects of PS-NPs and Cd on ovarian toxicity in adolescent rats: Ferroptosis by induction of mitochondrial redox imbalance via the SIRT3-SOD2/Gpx4 pathway by Hua Wu, Lihua Feng, Huang Wu, Lihong Wang, Hengyi Xu, Fen Fu

“…In this study, polystyrene nanoplastics (PS-NPs) and/or cadmium (Cd) were exposed to 4-week-old female rats for 28 days, with the aim of exploring the potential effects of combined exposure to PS-NPs and Cd on the ovaries of adolescence rats. …”
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Favorable Nonclinical Safety Profile of RSVpreF Bivalent Vaccine in Rats and Rabbits by Jun Zhou, Christopher J. Bowman, Vicki R. Markiewicz, Balasubramanian Manickam, Emily Gomme, Rani S. Sellers, Cynthia M. Rohde

“…It is the only RSV vaccine approved for both maternal immunization to protect infants and active immunization of older adults (≥60 years) and 18–59-year-old individuals with high-risk conditions for prevention of RSV disease. …”
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Surgical Resection of Anastomotic Stenosis after Rectal Cancer Surgery Using a Circular Stapler and Colostomy with Double Orifice by Toru Imagami, Satoru Takayama, Yohei Maeda, Taku Hattori, Ryohei Matsui, Masaki Sakamoto, Hisanori Kani

“…In an effort to propose a new resolution, reporting new cases and sharing valid experiences are necessary. An 82-year-old man diagnosed with rectal cancer had undergone laparoscopic anterior resection. …”
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Evaluation of Rivaroxaban Exposure via Anti-Xa Levels During VTE Prophylaxis in Hospitalized Patients by Kaitlin Blotske PharmD, Toral Patel PharmD, BCPS, Toby Trujillo PharmD, FCCP, FAHA, BCPS, Matthew Marlar MLS (ASCP), Stuart Lind MD, Henry Kramer MD, Kathryn Hassell MD, Tyree H. Kiser PharmD, FCCM, FCCP, BCCCP, BCPS

“…Patients were enrolled if they were between the ages of 18-89 years old, received rivaroxaban 10 mg daily, and had active orders for coagulation studies. …”
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Adherence to the ISHLT Protocol for the Referral of Patients with Idiopathic Pulmonary Fibrosis to the Transplantation Center among of Czech Centers for Interstitial Lung Diseases by Martina Sterclova, Martina Doubkova, Lubica Sykorova, Vladimir Bartos, Monika Zurkova, Vladimira Lostakova, Radka Mokosova, Martina Plackova, Ladislav Lacina, Michaela Cimrova, Radka Bittenglova, Pavlina Lisa, Pavla Musilova, Daniel Dolezal, Jana Psikalova, Petra Ovesna, Martina Koziar Vasakova

“…Czech patients who were diagnosed with IPF between 1999 and 2021 (n=1584) and who were less than 65 years old at the time of diagnosis were retrospectively selected from the Czech Republic of the European Multipartner Idiopathic Pulmonary Fibrosis Registry (EMPIRE). …”
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Clinical Impact of Viral Load on the Development of Hepatocellular Carcinoma and Liver-Related Mortality in Patients with Hepatitis C Virus Infection by Ran Noh, Doo Hyuck Lee, Byoung Woon Kwon, Yong Hyun Kim, Suk Bae Kim, Il Han Song

“…The cumulative risk of HCC development was higher in subjects with high HCV RNA titer (log HCV RNA IU/mL > 6) than subjects with low titer (log HCV RNA IU/mL ≦ 6) (HR = 4.63, P=0.032), giving an incidence rate of 474.1 and 111.5 per 10,000 person-years, respectively. Old age (HR = 9.71, P=0.014), accompanying cirrhosis (HR = 19.34, P=0.004), and low platelet count (HR = 13.97, P=0.009) were other independent risk factors for the development of HCC. …”
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Partial weight bearing and long-term survival outcomes in extracapsular hip fractures treated with trochanteric Gamma3 nails by Carlos Hernández-Pascual, José Ángel Santos-Sánchez, Jorge Hernández-Rodríguez, Carlos Fernando Silva-Viamonte, Carmen Pablos-Hernández, Pablo Alonso-Rodríguez, José Antonio Mirón-Canelo

“…Methods Retrospective cohort study of osteoporotic ECF in ≥ 65-year-old patients who underwent surgery with trochanteric Gamma3 nails in 2014 (n = 218), followed in the long-term (consolidation or stabilisation). …”
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Microencapsulated Escape Lysine with Tannin as an Adjuvant in Sheep Diets by Roberto Matheus Oliveira, José Morais Pereira Filho, Claudiney Inô, Évyla Andrade, Kevily Henrique Lucena, Juliana Paula Oliveira, Elzania Pereira, Ronaldo Oliveira, Ricardo Edvan, Leilson Bezerra

“…Forty intact male Santa Ines × Dorper sheep (~4 months old, BW 23 ± 1.2 kg) were allocated, in a randomized block design, to four treatments: control group (no lysine addition), supplementation with free lysine, escape lysine, and escape lysine + tannin extract. …”
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Pseudoaneurysm of the Anterior Tibial Artery following Ankle Arthroscopy in a Soccer Player by Ichiro Tonogai, Tetsuya Matsuura, Toshiyuki Iwame, Keizo Wada, Tomoya Takasago, Tomohiro Goto, Daisuke Hamada, Yohei Kawatani, Eiki Fujimoto, Tetsuya Kitagawa, Shyoichiro Takao, Seiji Iwamoto, Moriaki Yamanaka, Masafumi Harada, Koichi Sairyo

“…Here we reported a rare case of a 19-year-old soccer player who presented with pseudoaneurysm of the anterior tibial artery following ankle arthroscopy using an ankle distraction method and underwent anastomosis for the anterior tibial artery injury. …”
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Hepatitis due to Coxsackie A virus in an adult: a case report by Likith Surendra, Varun Sharma, Milan Sivakumar, Tara Lanzendorf, Thomas C. Varkey, Kaivan Salehpour

“…Case presentation The patient is a 35-year-old male who presented with acute epigastric and right upper quadrant pain. …”
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Determination of Palatal Soft Tissue Thickness and Safe Zone for Palatal Soft Tissue Harvest Using CBCT: A Retrospective Study by Hanan Aldhanhani, Bhavna Jha Kukreja, Sesha Reddy, Jovita D’souza, Hossam Abdelmagyd

“…For sex and nationality, there was no significant association (p>0.05), while for age, cases 35 years and older had significantly higher mucosal thickness than cases younger than 35 years old (p<0.001). For all teeth, the association was statistically significant (p<0.001). …”
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Spina Bifida Occulta with Bilateral Spondylolysis at the Thoracolumbar Junction Presenting Cauda Equina Syndrome by Kentaro Mataki, Masao Koda, Yosuke Shibao, Hiroshi Kumagai, Katsuya Nagashima, Kousei Miura, Hiroshi Noguchi, Toru Funayama, Tetsuya Abe, Masashi Yamazaki

“…We report a case of SBO with spondylolysis at L1, presenting cauda equine syndrome. A 37-year-old man presented with a gait disorder as a result of bilateral motor weakness of the lower extremities. …”
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Case Report: Combined Autoimmune Pancreatitis, Ulcerative Colitis and Sclerosing Cholangitis in 28-y.o. Patient by A. R. Khurmatullina, A. V. Okhlobystin, L. N. Androsova, R. T. Rzayev, A. S. Tertychnyy, A. P. Kiryukhin, O. Z. Okhlobystina, M. S. Zharkova, O. S. Shifrin, V. T. Ivashkin

“…Colonic lesions that initially had low grade of inflammation were resistant to immunosuppressive therapy.Key points. A 28-year-old female patient was admitted to the clinic for jaundice associated with pruritis. …”
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Multifield Coupling Mechanism of Unloading Deformation and Fracture of Composite Coal-Rock by Zhen Yang, Yan Li, Xin Li, Jiayu Zhuang, Hao Li, Xue Wang, Yuning Wang

“…Microscopically, the internal old molecular chains are broken to form new molecular chains by the force. …”
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Tetrastigma hemsleyanum as a feed additive: modulating gut microbiota for enhancing nutritional transport and growth performance in Jinhua yellow chickens by Chao Lu, Yun Xiang, Kewei Xu, Fengrui Gao, Shaofeng Zhu, Fangfang Lou, Lu Liu, Xin Peng

“…Herein, a total of 120 male Jinhua yellow chickens (two-mth-old) were randomly divided into into four groups (CON, TH-L, TH-M, and TH-H) for a 56-day feeding trial to explore its effects on growth performance and underlying mechanism. …”
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Standard reference values of the upper body posture in healthy young female adults in Germany: an observational study by Daniela Ohlendorf, Charlotte Doerry, Vanessa Fisch, Sebastian Schamberger, Gerhard Oremek, Hanns Ackermann, Johannes Schulze

“…However, standard values have been published for healthy male adults but not for female adults.Design Observational study.Setting Institute of Occupational Medicine, Social Medicine and Environmental Medicine, Goethe-University Frankfurt/Main.Participants 106healthy female volunteers (21–30 years old; 25.1±2.7 years) were included. Their body weight ranged from 46 to 106 kg (60.3±7.9 kg), the heights from 1.53 to 1.82 m (1.69±0.06 m) and the body mass index from 16.9 kg/m² to 37.6 kg/m² (21.1±2.6 kg/m²).Outcome measures A three-dimensional back scan was performed to measure the upper back posture in habitual standing. …”
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