Pembrolizumab with external radiation therapy effectively controlled TMB-high unresectable recurrent parathyroid cancer: a case report with review of literature by Hiroshi Katoh, Tomoya Mitsuma, Riku Okamoto, Kanako Naito, Takaaki Tokito, Mariko Kikuchi, Takafumi Sangai

“…Here, we report a case of unresectable tumor mutational burden (TMB)-high recurrent PC that has been effectively controlled by pembrolizumab (PEM) with RT. A 48-year-old male patient, with previous history of left single parathyroidectomy for primary hyperparathyroidism, underwent surgeries for recurrent hyperparathyroidism at 47 and 48 years of age, and was pathologically diagnosed with PC. …”
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A Manajemen Fisioterapi pada Suspek Gout Arthritis : Laporan Kasus by Yery Mustari, Melda Putri, Christine Milenia Sarira, Suciawati Suciawati, Rezky Awalia Amiruddin, Fahira Azzahra Nooraini, Noorindah Sari, Putri Ayuninda Yusri, Pritha Qurratul Aini Athaya, Akram Ibnu Syawal, Anna Rahma Martono, Nurdeli Wasi Agung, Marfuah Nawawi, Nurmalasari Nurmalasari

“…This case report contains physiotherapy management of a case of suspected gouty arthritis in a 26 year old woman with the main complaint of pain, stiffness and swelling in the left ankle. …”
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Rare Manifestation of a c.290 C>T, p.Gly97Glu VCP Mutation by Nivedita U. Jerath, Cameron D. Crockett, Steven A. Moore, Michael E. Shy, Conrad C. Weihl, Tsui-Fen Chou, Tiffany Grider, Michael A. Gonzalez, Stephan Zuchner, Andrea Swenson

“…Consistent with this, VCP mutations manifest variable clinical phenotypes among and within families and are a diagnostic challenge. Methods. A 60-year-old man who played ice hockey into his 50’s was evaluated by electrodiagnostics, muscle biopsy, and molecular genetics. …”
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A Dietary Treatment Improves Cerebral Blood Flow and Brain Connectivity in Aging apoE4 Mice by Maximilian Wiesmann, Valerio Zerbi, Diane Jansen, Roy Haast, Dieter Lütjohann, Laus M. Broersen, Arend Heerschap, Amanda J. Kiliaan

“…At 10–12 months, apoE4 mice did not display prominent pathological differences compared to wild-type (WT) mice. However, 16–18-month-old apoE4 mice revealed reduced CBF and accelerated synaptic loss. …”
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Management of Multiple Arteriovenous Malformations of the Small Bowel by Masahiro Hirakawa, Rie Ishizuka, Masanori Sato, Naotaka Hayasaka, Hiroyuki Ohnuma, Kazuyuki Murase, Kohichi Takada, Tatsuya Ito, Takayuki Nobuoka, Koji Miyanishi, Masayoshi Kobune, Ichiro Takemasa, Junji Kato

“…A 62-year-old Japanese female was referred to our hospital with gastrointestinal bleeding. …”
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Lighting quality evaluation on growth performance and feather pecking behavior of broilers by Chenghao Pan, Rong Xiang, Jinming Pan

“…One hundred and twenty 49-day-old Youhuang broilers were randomly distributed into 3 lighting treatment groups (warm white, cold white and red) and reared for 4 weeks. …”
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Assessment of Factors Affecting Time to Recovery from COVID-19: A Retrospective Study in Ethiopia by Anteneh Mengist Dessie, Sefineh Fenta Feleke, Denekew Tenaw Anley, Rahel Mulatie Anteneh, Zelalem Animut Demissie

“…Patients without comorbid illness/s were faster to recover than their counterparts (AHR = 1.44 : 95% CI: 1.10, 1.91) and those who have signs and symptoms on admission (AHR = 0.42 : 95% CI: 0.30, 0.60) and old-aged (AHR = 0.988; 95% CI: 0.982, 0.994) took longer to recover. …”
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Perioperative Management of a Patient with Hereditary Angioedema and Intestinal Obstruction Secondary to an Ileal Tumor: A Case Report by Antony Peter Gatheru, Anne Kasyoka Barasa, Isaac Karogo Mwangi, Stanley Ngare, Dan Kiptoon, Edwin Oloo Walong

“…We describe the successful management of a 41-year-old female with HAE presenting with features of intestinal obstruction, which only partially resolved with the administration of C1-INH and conservative bowel decompressive management. …”
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Nephrotic Syndrome and Idiopathic Membranous Nephropathy Associated with Autosomal-Dominant Polycystic Kidney Disease by Ramón Peces, Jorge Martínez-Ara, Carlos Peces, Mariluz Picazo, Emilio Cuesta-López, Cristina Vega, Sebastián Azorín, Rafael Selgas

“…We report the case of a 38-year-old male with autosomal-dominant polycystic kidney disease (ADPKD) and concomitant nephrotic syndrome secondary to membranous nephropathy (MN). …”
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Phenotype of the First Gynogenesis Generation of Koi by , Alimuddin, K. Sumantadinata, Yani Hadiroseyani, D. Irawan

“…Analysis on body coloration of fish was carried out at three months old. Results showed that gynogenesis from kohaku produced three types of koi, those were white koi, red koi and kohaku, and hi-utsuri produced red koi, black koi and hi-utsuri. …”
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A Woman with a Long History of Smoking and a Debilitating Dry Cough by N. D. Potskhverashvili, N. I. Kokina, E. L. Bueverova, O. Yu. Zolnikova, A. S. Cherenda, V. A. Morozova, M. V. Feldsherov, A. P. Kiryukhin, P. V. Pavlov

“…Aim: to present a clinical case of colorectal cancer in a woman with a long history of smoking and a leading complaint of dry cough.Key points. A 56-year-old patient with a long history of smoking was hospitalized in the pulmonology department of the clinic with a leading complaint of a constant debilitating dry cough during the day, not amenable to the action of drugs, as well as general weakness, sweating and weight loss by 2 kg in 3 months. …”
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Evaluation of Sociodemographic Factors among Diabetic Patients with Urinary Tract Infections in Kisii Referral Hospital, Kenya by Vincent M. Mageto, Oliver W. Mbuthia, Caroline J. Ngetsa, Dinah O. Moraa, Erick O. Okoyo, Scholastica G. Mathenge, Wachuka G. Njoroge

“…The majority of the participants were between the age of 55 and 59 years old (77.2%), and 125 participants (69.4%) had attained tertiary education as the highest level of education. …”
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The production process of chepa shutki: A traditional Bangladeshi fermented fish product by Jasmin Ara Farhana, Sijmen E. Schoustra, Ferdous Ahamed, Bas Zwaan, Oscar van Mastrigt

“…Types of fish, types of fermentation container (old/new) and fermentation time were identified as vital process parameters. …”
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Successful Tocilizumab Therapy for Macrophage Activation Syndrome Associated with Adult-Onset Still’s Disease: A Case-Based Review by Eri Watanabe, Hitoshi Sugawara, Takeshi Yamashita, Akira Ishii, Aya Oda, Chihiro Terai

“…We report the case of a 71-year-old Japanese woman with adult-onset Still’s disease (AOSD) in whom macrophage activation syndrome (MAS) developed despite therapy with oral high-dose prednisolone and intravenous methylprednisolone pulse therapy twice. …”
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Composite paraganglioma-ganglioneuroma with atypical catecholamine profile and phenylethanolamine N-methyltransferase expression: a case report and literature review by Yuriko Sasaki, Maki Kanzawa, Masaaki Yamamoto, Keitaro Kanie, Hironori Bando, Kei Yoshino, Yushi Hirota, Katsumi Shigemura, Masato Fujisawa, Wataru Ogawa, Hidenori Fukuoka

“…We present the case of a 46-year-old woman with an atypical catecholamine profile who was preoperatively diagnosed with pheochromocytoma. …”
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Fatal Renal Failure in a Spinal Cord Injury Patient with Vesicoureteric Reflux Who Underwent Repeated Ureteric Reimplantations Unsuccessfully: Treatment Should Focus on Abolition o... by Subramanian Vaidyanathan, Bakul Soni, Kottarathil Abraham Abraham, Peter Hughes, Gurpreet Singh

“…A 29-year-old man developed paraplegia at T-10 level due to road traffic accident in 1972. …”
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Septic shock caused by emphysematous hepatitis complicated with intracranial infection by Miao Chen, Jianbo Chen, Zhengzhi Zhuang, Xiaojun He, Yue Wang, Junwen Liang, Runpei Lin, Gengxin Cai

“…Method: We report a case of septic shock caused by emphysematous hepatitis complicated with intracranial infection, and review the current literature on emphysematous hepatitis. Results: A 57-year-old male with uncontrolled diabetes mellitus developed emphysematous hepatitis complicated with intracranial infection, which progressed to septic shock. …”
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INFLUENCE OF DOSED BASED PROBIOTICS (Lactobacillus) ON BLOOD AND MICROBIAL INDICES OF BROILERS by Egbunike Chiazor Maryjan, Ironkwe Monica Ogochukwu, Boma Victor Iriso

“…This study was carried to evaluate the effect of probiotics (Lactobacillus) on the blood parameters and microbial load of one hundred and twenty day old unsexed Abor Acres+ for a period of eight weeks. …”
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The effect of different amounts of bıotin in broilers' ration on growth performance and fatty liver syndrome by Şakir Doğan Tuncer, Reşat Aştı, Behiç Coşkun, Erdoğan. Şeker, Ülker Demirci

“…In this study, 1000 day-old Hybro chicks were used. They were distributed into 4 groups, each group containing 250 chicks and the experiment was ended at the 49th day.…”
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An Unusual Case of Systemic Inflammatory Myofibroblastic Tumor with Successful Treatment with ALK-Inhibitor by Sanjivini V. Jacob, John D. Reith, Angerika Y. Kojima, William D. Williams, Chen Liu, Lizette Vila Duckworth

“…Systemic inflammatory myofibroblastic tumor is an exceedingly rare entity. A 45-year-old Hispanic female presented with a 6-month history of left-sided thigh pain, low back pain, and generalized weakness. …”
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