Serum NT-Pro-BNP versus Noninvasive Bedside Inotropic Index in Paediatric Shock: A Contest of Myocardial Performance in Response to Fluid Loading by Antonius Hocky Pudjiadi, Tuty Rahayu, Stephanie Wijaya, Fatima Safira Alatas

“…Higher median NT-pro-BNP (preloading NT-pro-BNP of 1175.00 (254.50–9965.00) ng/mL vs. 196.00 (65.00–509.00) ng/mL, p=0.002) was associated with fluid nonresponders (subjects >12 months old). Preloading NT-pro-BNP <242.5 ng/mL was associated with fluid responders (AUC: 0.768 (0.615–0.921), p=0.003), 82.1% sensitivity, and 68.7% specificity for subjects >12 years old. …”
Get full text

Stroke Induces a BDNF-Dependent Improvement in Cognitive Flexibility in Aged Mice by Josh Houlton, Lisa Y. Y. Zhou, Deanna Barwick, Emma K. Gowing, Andrew N. Clarkson

“…As neurotrophic support diminishes with age, we also investigated the involvement of brain-derived neurotrophic factor (BDNF) in these differences. Young (3-6 months old) and aged (16-21 months old) mice were trained in operant touchscreen chambers to complete a visual pairwise discrimination (VD) task. …”
Get full text

Genetic diversity of the immunoglobulin heavy chain locus in cohorts of patients affected with SARS-CoV-2 by Patrizia Malaspina, Carla Jodice, Bianca Maria Ciminelli, Michela Biancolella, Vito Luigi Colona, Andrea Latini, Francesca Leonardis, Paola Rogliani, Antonio Novelli, Giuseppe Novelli, Andrea Novelletto

“…Two haplotypes were underrepresented in young severe cases compared to old severe ones. The same two haplotypes were overrepresented among young Resistors. …”
Get full text

Black Chokeberry (<i>Aronia melanocarpa</i>) Juice Supplementation Affects Age-Related Myocardial Remodeling in Rats by Elena Daskalova, Mina Pencheva, Slavi Delchev, Lyudmila Vladimirova-Kitova, Spas Kitov, Stoyan Markov, David Baruh, Petko Denev

“…Methods: Healthy male Wistar rats (n = 24) were divided into three groups: (1) young controls (CY)—age 2 months; (2) old controls (CO)—age 27 months; (3) AMJ group—27-month-old animals, supplemented with <i>Aronia melanocarpa</i> juice (AMJ) at a dose of 10 mL∙kg⁻¹ for 105 days. …”
Get full text

Home Medication Review among Patients with Chronic Diseases in Rural Villages of Pahang, Malaysia: A Case Report by Norny Syafinaz Ab Rahman, Nur Alyaa Anisa Mat Harom, Nor Ilyani Mohamed Nazar

“…The second case involves a 34-year-old married Malay female diagnosed with hypertension and T2DM, receiving nine prescribed medications. …”
Get full text

Prescription of Strong Opioids in Chronic Non-Cancer Pain in the Province of Valladolid (Spain) by Rodrigo Enríquez de Salamanca Gambara, Ana María Sierra Santos, Ana María Ruiz San Pedro, Federico Montero Cuadrado, Irene Muñoz León, Miguel Ángel Castro Villamor, Alicia Córdoba Romero, Ana María Del Olmo Tornero, Lucía Pérez Pérez, León Morales-Quezada

“…The highest consumption in nº DDDs was in patients who lived in nursing homes, were over 70 years old and were resident in rural areas. The number of DDDs from 2020 to 2023 for SOs in DCNO increased by 41%. …”
Get full text

Oral glucose tolerance testing as a complement to fasting plasma glucose in screening for type 2 diabetes: population-based cross-sectional analyses of 146 000 health examinations... by Patrik Wennberg, Mattias Brunström, Anna Rosén, Julia Otten, Andreas Stomby, Simon Vallin

“…The estimated NNS to prevent one case of T2D through detection and lifestyle treatment of IGT ranged from 1332 among 40-year-old men without risk factors, to 39 among 60-year-old women with all risk factors combined.Conclusions The prevalence of hyperglycaemia on OGTT is highly dependent on age, sex and risk factor burden; OGTT should be applied selectively to high-risk groups to avoid unnecessary testing in the general population.…”
Get full text

Evaluation of Government Programmes on Enhancing the Lives of the Elderly: A Case Study of Social Assistance Grant for Empowerment in Mitooma District. by Natuha, Prossy

“…The study concludes that old age is inevitable and as long as old age comes with poverty, people will fear older persons therefore, we must support older persons in reaching their potential by developing opportunities for them to continue as economically active citizens and leaders of the community. …”
Get full text

Acute generalized exanthematous pustulosis induced by ceftriaxone with positive patch testing by Ana Gabriela Lopes, Carmem Botelho, Lise Brosseron

“…Our case involves an 87-year-old female patient, treated for a periprosthetic joint infection with ceftriaxone and daptomycin, who developed acute generalized exanthematous pustulosis. …”
Get full text

Acute Rheumatic Fever in a COVID-19-Positive Pediatric Patient by Christa I. DeVette, Cherise S. Ali, Devon W. Hahn, Stephanie D. DeLeon

“…Discussed here is the clinical course of an 8-year-old COVID-positive female with pure Sydenham’s chorea and subclinical carditis from acute rheumatic fever. …”
Get full text

Extensive supraglottic mass—An anesthetist’s nightmare by K Chethan Hebbar, Abhishek Nagarajappa, M Chandramouli, Anvi

“…We report a case of a 26-year-old female with extensive supraglottic growth undergoing a biopsy. …”
Get full text

Bortezomib Use for a Critically Ill Patient with Angioimmunoblastic T-Cell Lymphoma by Motoharu Shibusawa

“…This case describes the use of bortezomib in newly diagnosed AITL. A 53-year-old man with no previous illness presented with erythema and swelling in the left neck. …”
Get full text

Cutaneous Squamous Cell Carcinoma with Invasion through Ear Cartilage by Julie Boisen, C. Helen Malone, Brent Kelly, Richard F. Wagner

“…We present the unusual case of a 76-year-old man with an auricular squamous cell carcinoma that exhibited full-thickness perforation of the scapha cartilage. …”
Get full text

Cryptococcal cerebrospinal fluid shunt infection treated with fluconazole by Daniel Eymard, François Lebel

“…A 37-year-old woman with a cadaveric renal allotransplantation required intra-cranial shunting devices after a presumptive episode of tuberculous meningitis. …”
Get full text

Unusual Presentation of Leiomyoma in the Hindfoot by Abdullah Zaher, Jaouad Yasser, Daniel Badaro, Noureddine Sekkach

“…We present a case of a 57-year-old female patient who presented to the clinic for a painless mass on the posteromedial side of the right heel. …”
Get full text

A Case of Anti-SAE1 Dermatomyositis by Max de Vries, Marco W. J. Schreurs, Els J. M. Ahsmann, Marcela Spee-Dropkova, Faiz Karim

“…Case Description. A 61-year-old woman presented with progressive shortness of breath, arthralgia, heliotrope rash, Gottron’s papules, and erythematous rash. …”
Get full text

Self-Inflicted Needle Injuries to the Eye: A Curing Pain by Shahrokh Amiri, Asghar Arfaei, Sara Farhang

“…We report on a 41-year-old woman, primarily visiting for symptoms of endophthalmitis resulting from self-inflicted needles. …”
Get full text

Gingival Cyst of the Adult: Report of an Inconspicuous Lesion Associated with Multiple Agenesis by Juliana Mançano Melhado Brod, Fabrício Passador-Santos, Andresa Borges Soares, Marcelo Sperandio

“…The present report describes the case of a miniscule adult gingival cyst in the lower anterior gingiva in a 51-year-old male with agenesis of lower premolars and lateral incisors. …”
Get full text

Bilateral Intracavernous Carotid Artery Aneurysms Presenting as Diplopia in a Young Patient by Nikolaos Kopsachilis, Maria Pefkianaki, Gianluca Carifi, Ioannis Lialias

“…Case Report. A 26-year-old female presented in our clinic with acute diplopia due to oculomotor nerve palsy on the left side. …”
Get full text