Biomarkers of Periodontal Tissue Remodeling during Orthodontic Tooth Movement in Mice and Men: Overview and Clinical Relevance by Fabrizia d'Apuzzo, Salvatore Cappabianca, Domenico Ciavarella, Angela Monsurrò, Armando Silvestrini-Biavati, Letizia Perillo

“…The relevance for clinicians of evaluating the rate of some substances as valid biomarkers of periodontal effects during orthodontic movement, by means of two models of study, mice and men, is underlined.…”
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Reduced Numbers and Impaired Function of Regulatory T Cells in Peripheral Blood of Ischemic Stroke Patients by Johanna Ruhnau, Juliane Schulze, Bettina von Sarnowski, Marie Heinrich, Sönke Langner, Christian Pötschke, Anika Wilden, Christof Kessler, Barbara M. Bröker, Antje Vogelgesang, Alexander Dressel

“…CD39 expression on Treg increased with age in peripheral blood of mice and men. Conclusion. We demonstrate a loss of active FoxP3+CD39+ Tregs from stroke patient’s peripheral blood. …”
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Glucocorticoid-Induced TNFR-Related (GITR) Protein and Its Ligand in Antitumor Immunity: Functional Role and Therapeutic Modulation by Theresa Placke, Hans-Georg Kopp, Helmut Rainer Salih

“…Not only GITR, but also GITRL is capable of transducing signals, and the consequences of GITR-GITRL interaction may vary among different effector cell types, differ upon signal transduction via the receptor, the ligand, or both, depend on the level of an ongoing immune response, and even differ among mice and men. In this paper, we address available data on GITR and its ligand in immune responses and discuss the role and potential therapeutic modulation of this molecule system in antitumor immunity.…”
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