Cost-Benefit Analysis of Genetic Testing as a Prenatal Diagnostic Tool for Thalassemia: A Single-Center Study From Central Thailand by Malasai K, Jittikoon J, Udomsinprasert W, Talungchit P, Youngkong S, Sangroongruangsri S, Mahasirimongkol S, Chaikledkaew U

“…Kwandao Malasai,1,2 Jiraphun Jittikoon,3 Wanvisa Udomsinprasert,3 Pattarawalai Talungchit,4,5 Sitaporn Youngkong,5,6 Sermsiri Sangroongruangsri,6 Surakameth Mahasirimongkol,7 Usa Chaikledkaew5,6 1Social, Economic and Administrative Pharmacy (SEAP) Graduate Program, Faculty of Pharmacy, Mahidol University, Bangkok, Thailand; 2Social Pharmacy Research Unit, Faculty of Pharmacy, Mahasarakham University, Maha Sarakham, Thailand; 3Department of Biochemistry, Faculty of Pharmacy, Mahidol University, Bangkok, Thailand; 4Department of Obstetrics and Gynecology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand; 5Mahidol University Health Technology Assessment (MUHTA) Graduate Program, Mahidol University, Bangkok, Thailand; 6Social and Administrative Pharmacy Division, Department of Pharmacy, Faculty of Pharmacy, Mahidol University, Bangkok, Thailand; 7Information and Communication Technology Center, Office of the Permanent Secretary, Ministry of Public Health, Nonthaburi, ThailandCorrespondence: Usa Chaikledkaew, Social and Administrative Pharmacy Division, Department of Pharmacy, Faculty of Pharmacy, Mahidol University, 447 Sri-Ayudhaya Road, Rachathewi, Phayathai, Bangkok, 10400, Thailand, Email usa.chi@mahidol.ac.thPurpose: This study aimed to evaluate the costs and benefits of genetic testing, specifically mutation analysis and prenatal diagnostic testing, for the confirmation of thalassemia in at-risk pregnancies in Thailand, providing crucial insights to inform public health policy decision-making.Patients and Methods: We analyzed the costs and benefits of following standard screening guidelines, which included a sequence of tests such as mean corpuscular volume (MCV)/mean corpuscular hemoglobin (MCH) with dichlorophenol indophenol precipitation (DCIP), hemoglobin (Hb) typing, genetic testing, and amniocentesis. …”
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Comparative efficacy of lumbar and pelvic support on pain, disability, and motor control in women with postpartum pelvic girdle pain: a three-armed randomized controlled trial by Fahimeh-Sadat Jafarian, Mahmonir Jafari-Harandi, Gillian Yeowell, Ebrahim Sadeghi-Demneh

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Effect of improving food security on parenting practices and caregiver–adolescent relationships: qualitative findings of an income-generating agricultural intervention in rural Ken... by Maricianah A. Onono, Lila Sheira, Edward A. Frongilio, Gladys Odhiambo, Pauline Wekesa, Amy Conroy, Elizabeth A. Bukusi, Craig R. Cohen, Sheri D. Weiser

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Effect of High Pressure and Sub-Zero Temperature on Total Antioxidant Capacity and the Content of Vitamin C, Fatty Acids and Secondary Products of Lipid Oxidation in Human Milk by Martysiak-Żurowska Dorota, Puta Małgorzata, Barczak Natalia, Dąbrowska Joanna, Malinowska-Pańczyk Edyta, Kiełbratowska Bogumiła, Kołodziejska Ilona

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GRK6 palmitoylation dictates triple-negative breast cancer metastasis via recruiting the β-Arrestin 2/MAPKs/NF-κB signaling axis by Wen-Ke Wang, Hui-Yu Lin, Che-Hsuan Lin, Hsun-Hua Lee, Yen-Lin Chen, Yu-Hsien Kent Lin, Hui-Wen Chiu, Shry-Ming Sheen-Chen, Yuan-Feng Lin

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Double-blind, randomised, placebo-controlled trial to evaluate the effectiveness of late gestation oral melatonin supplementation in reducing induction of labour rates in nulliparo... by Miranda Davies-Tuck, Emily Callander, Mary Sharp, Scott W White, Dorota A Doherty, Jane Warland, Zoe Bradfield, Lesley Kuliukas, Monique Rose, Amber Pettitt, Kylie Ekin, JA Keelan

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Outcomes following intradetrusor onabotulinumtoxinA in a national cohort of nursing home residents by Leo D. Dreyfuss, Farnoosh Nik‐Ahd, Lufan Wang, Abigail Shatkin‐Margolis, Kenneth Covinsky, W. John Boscardin, Anne M. Suskind

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Low L3 skeletal muscle index and endometrial cancer: a statistic pooling analysis by Na Aru, Congyu Yang, Yuntian Chen, Jiaming Liu

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The Potential Impact of Dietary Fiber Supplementation on Hemoglobin and Reticulocyte Hemoglobin Equivalent (RET-He) Levels in Pregnant Women with Anemia Receiving Oral Iron Therapy... by Afifah A, Zuhairini Y, Ariyanto EF, Ghozali M, Fatimah SN, Pramatirta AY

“…Adilah Afifah,1 Yenni Zuhairini,2 Eko Fuji Ariyanto,3 Mohammad Ghozali,3 Siti Nur Fatimah,2 Akhmad Yogi Pramatirta4 1Master Program of Biomedical Sciences, Faculty of Medicine, Universitas Padjadjaran, Bandung, West Java, 40161, Indonesia; 2Department of Public Health, Faculty of Medicine, Universitas Padjadjaran, Sumedang, West Java, 45363, Indonesia; 3Department of Biomedical Sciences, Faculty of Medicine, Universitas Padjadjaran, Sumedang, West Java, 45363, Indonesia; 4Department of Obstetrics and Gynecology, Faculty of Medicine, University of Padjadjaran, Dr. …”
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Neural tube defects in a war-torn Tigray regional state of Ethiopia: a retrospective study of 54,626 deliveries by Birhane Alem Berihu, Afework Mulugeta, Tony Magana, Masresha Tessema, Tafere Gebreegziabher, Yibrah Berhe, Abadi Leul Welderufael, Hayelom Kebede Mekonen

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Women and birth partners’ experiences of cervical ripening at home and in hospital by Cassandra Yuill, Mairi Harkness, Helen Cheyne, Boo Charkin, Monica Ferreira, Eloise Price, Amarnath Bhide, Mairead Black, Kathleen Boyd, Neelam Heera-Shergill, Neena Modi, John Norrie, Dharmintra Pasupathy, Julia Sanders, Sarah J. Stock, Rosemary Townsend, Linda J. Williams, Christine McCourt

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SETD2 loss-of-function uniquely sensitizes cells to epigenetic targeting of NSD1-directed H3K36 methylation by Ryan T. Wagner, Ryan A. Hlady, Xiaoyu Pan, Liguo Wang, Sungho Kim, Xia Zhao, Louis Y. El Khoury, Shafiq Shaikh, Jian Zhong, Jeong-Heon Lee, Jolanta Grembecka, Tomasz Cierpicki, Thai H. Ho, Keith D. Robertson

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Incidence and risk factors for clinical omphalitis among neonates in Eastern Uganda using chlorhexidine gel for cord care: a community-cohort study by John Wogabaga, Kathy Burgoine, Abel Kakuru, Brendah Nambozo, Martin Chebet, Josephine Tumuhamye, Benon Wanume, Faith Oguttu, Milton W. Musaba, Agnes Napyo, Solomon Wani, Peter Olupot-Olupot, Andrew D. Weeks, Thorkild Tylleskär, David Mukunya

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Correlation Between Systemic Inflammation, Gut Microbiome Dysbiosis and Postoperative Complications After the Modified Whipple Procedure by Gelu Mihai Breaza, Florin Emil Hut, Octavian Cretu, Simona-Alina Abu-Awwad, Ahmed Abu-Awwad, Laurențiu Vasile Sima, Radu Gheorghe Dan, Cristina Ana-Maria Dan, Raluca Maria Closca, Flavia Zara

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Effect of intraoperative noise isolation on postoperative nausea and vomiting in patients undergoing gynecological laparoscopic surgery: protocol for a randomized controlled trial by Chong Fu, Fan Xia, Zihan Yan, Han-bing Xu, Wei-ming Zhao, Yi-shan Lei, Chang Xu, Wen-wen Huo, Duo-duo Tao, Juan Wang, Xi-sheng Shan, Ke Peng, Hong Liu, Fu-hai Ji, Hua-yue Liu

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Prediction model study focusing on eHealth in the management of urinary incontinence: the Personalised Advantage Index as a decision-making aid by Huibert Burger, Henk van der Worp, Marco H Blanker, Marjolein Y Berger, Anne Martina Maria Loohuis, Nienke Wessels, Janny Dekker, Alec GGA Malmberg

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Cyclin E1/CDK2 activation defines a key vulnerability to WEE1 kinase inhibition in gynecological cancers by Daehwan Kim, Heekyung Chung, Wen Liu, Kangjin Jeong, Tugba Y. Ozmen, Furkan Ozmen, Matthew J. Rames, Sangyub Kim, Xiao Guo, Nathan Jameson, Petrus R. de Jong, Steven Yea, Laurie Harford, Jiali Li, Cara A. Mathews, Deborah B. Doroshow, Vincent J. Charles, Doris Kim, Kimberlee Fischer, Ahmed A. Samatar, Adrian Jubb, Kevin D. Bunker, Kimberly Blackwell, Fiona Simpkins, Funda Meric-Bernstam, Gordon B. Mills, Olivier Harismendy, Jianhui Ma, Mark R. Lackner

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Hsa-miR-532-3p protects human decidual mesenchymal stem cells from oxidative stress in recurrent spontaneous abortion via targeting KEAP1 by Hong Zhou, Jiaxin Zhou, ShanShan Liu, Jing Niu, Jinghua Pan, Ruiman Li

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Associations of Serum Cystatin C, DNAm Cystatin C, Renal Function, and Mortality in U.S. Adults by Yu-Wei Fang, Wei-Chung Huang, Chikang Wang, Chien-Yu Lin

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Atopic dermatitis in childhood and pubertal development: A nationwide cohort studyCapsule Summary by Camilla Lomholt Kjersgaard, MD, Andreas Ernst, MD, PhD, Pernille Jul Clemmensen, MD, PhD, Lea Lykke Harrits Lunddorf, MD, PhD, Linn Håkonsen Arendt, MD, PhD, Nis Brix, MD, PhD, Onyebuchi A. Arah, MD, PhD, Mette Deleuran, MD, PhD, Cecilia Høst Ramlau-Hansen, MHSc, PhD

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