The Impact of Nutritional Status and Tumor-Infiltrating Lymphocytes (CD4+ and CD8+) on Chemotherapy Response in Colorectal Cancer Patients by Lukman K, Septianto R, Rudiman R, Ruchimat T, Sribudiani Y, Nugraha P, Primastari E, Budiman D

“…Regarding chemotherapy responses in patients with colorectal cancer, this study aims to investigate the association between nutritional status and infiltrating lymphocyte counts, specifically CD4+ and CD8+.Materials and Methods: This prospective observational study analyzed the impact of nutritional status using body mass index (BMI) and TILs levels (CD4+/CD8+) on chemotherapy outcomes in CRC patients treated at a tertiary hospital in West Java, Indonesia, from July 2023 to June 2024.Results: Thirty-six research subjects were included. …”
Get full text

PIK3CA mutational status in tissue and plasma as a prognostic biomarker in HR+/HER2− breast cancer by Eduardo Terán, Rebeca Lozano, César A. Rodríguez, Mar Abad, Luis Figuero, José Antonio Muñoz, Belén Cigarral, Aline Rodrígues, Magdalena Sancho, M. Asunción Gómez, Daniel Morchón, Juan Carlos Montero, José María Sayagués, M. Dolores Ludeña, Emilio Fonseca

“…Methods A retrospective and unicentric analysis of PIK3CA mutational status in tissue and plasma samples by Cobas®PIK3CA Mutation Kit in patients with HR+/HER2− BC. …”
Get full text

Variations in vitamin D status among Chinese children aged 1–6 years during the COVID-19 pandemic by Yongfeng Qiao, Xiaoqin Wang, Yanfen Ma, Jian Hu

“…Total 25(OH)D concentrations were compared between the two observation periods. Vitamin D status was determined by 25(OH)D concentrations: deficient (<20 ng/ml), insufficient (20–29 ng/ml), and sufficient (30–100 ng/ml).ResultsThe study involved 6,780 children, with 52.8% being 1-year-olds, 23.1% being 2-year-olds, and 24.1% being 3 to 6-year-olds. …”
Get full text

Sociodemographic disparities in awareness of chronic conditions: an observational study among older persons in rural north-east of South Africa by Francesc Xavier Gómez-Olivé, Chodziwadziwa Kabudula, Carlos Riumallo-Herl, Daniel Ohene-Kwofie

“…Awareness rates were relatively high among those with at least one chronic condition but varied across conditions and genders: HIV (83% for women, 84% for men), hypertension (88% of women, 81% of men); diabetes (76% for women, 75% for men); dyslipidaemia (10% for both women and men). We observe differences across individual, household and community factors. …”
Get full text

Acute-on-Chronic Liver Failure in Pregnant Patients with Chronic Hepatitis B: A Retrospective Observational Case Series Study by Shiwei Wang, Haofeng Xiong, Changling Luo, Hong Zhao, Ying Fan, Ting Zhang, Lili Wang, Qi Wang, Wen Xie

Get full text

Comparison of Tools for Nutritional Assessment and Screening of Hospitalized Patients: A study on Surgical Patients by Susetyowati SUSETYOWATI, Amalia Sarah SHOLIKHATI, Dinda Krisma CAHYANINGRUM, Azizah Isna RACHMAWATI, Adeodatus Yuda HANDAYA

Get full text

Stability of small incision lenticule extraction over laser in situ keratomileusis at an altitude of 3874 m by Yanming Huang, Yuancheng Zhao, Xiaofan Chen, Huan zou, Rongdi Yuan

Get full text

Outpatient chemotherapy drug costs and expensive chemotherapy drug use in 340B and Non-340B hospitals: an observational study by Jianhui Hu, David R. Nerenz

“…Methods This is an observational study using data from SEER-Medicare and 340B entity database. …”
Get full text

The Impact of 3S2E Nursing Management on the Psychological Status of Respiratory Function and Quality of Life of Patients with Severe Pneumonia in the ICU by Yaoyao Xu, Xia Li, Qin Yang, Xiuxian Ma

“…This study examines the effects of the 3S2E nursing management mode on patients with severe pneumonia in the intensive care unit’s respiratory function, psychological status, and quality of life (ICU). Methods. According to a random number table, 82 ICU patients with severe pneumonia who were admitted between March 2021 and March 2022 were enrolled and assigned to the control and observation class (n = 41, respectively) in a 1 : 1 ratio. …”
Get full text

Digestive Fermentation, Antioxidant Status, and Haemato-Biochemical Indices of Growing Rabbits Fed on Diets Supplemented with Ziziphus spina-christi Leaf by Suha Hashim Abduljawad

“…The objective of the study was to assess the effect of diets supplemented with Ziziphus spina-christi leaf on digestive fermentation, antioxidant status, and haemato-biochemical indices of growing rabbits. …”
Get full text

Pilocarpine-Induced Status Epilepticus Is Associated with Changes in the Actin-Modulating Protein Synaptopodin and Alterations in Long-Term Potentiation in the Mouse Hippocampus by Maximilian Lenz, Marina Ben Shimon, Thomas Deller, Andreas Vlachos, Nicola Maggio

“…Some patients may experience status epilepticus, a life-threatening state of ongoing seizure activity associated with postictal cognitive dysfunction. …”
Get full text

Alarming rise in prevalence of obesity among children with essential hypertension: Reflection of larger global epidemiological change of adolescent nutritional status by Vishwak Gundeti, Shrikiran Aroor, Koushik H, Leslie E. Lewis, Suneel C. Mundkur, Ramesh Bhat Y, Pushpa Kini

Get full text

Impact of Preoperative Three-Dimensional Computed Tomography Cholangiography on Postoperative Resection Margin Status in Patients Operated due to Hilar Cholangiocarcinoma by A. Andert, P. Bruners, C. Heidenhain, F. Ulmer, C. D. Klink, P. H. Alizai, C. Kuhl, U. P. Neumann, M. Binnebösel

“…Curative liver resection with R0 status was reached in 88% of patients in group ERC and 87% of patients in group 3D-ERC (p=1.00). …”
Get full text

Food Insecurity and Not Dietary Diversity Is a Predictor of Nutrition Status in Children within Semiarid Agro-Ecological Zones in Eastern Kenya by Zipporah N. Bukania, Moses Mwangi, Robert M. Karanja, Richard Mutisya, Yeri Kombe, Lydia U. Kaduka, Timothy Johns

“…Weight and height, or length in children, were used for computation of nutritional status. Findings. No significant difference (P>0.05) was observed in food security and dietary diversity score (DDS) between LM4 and LM5. …”
Get full text

The Expression Level of mRNA, Protein, and DNA Methylation Status of FOSL2 of Uyghur in XinJiang in Type 2 Diabetes by Jun Li, Siyuan Li, Ying Hu, Guolei Cao, Siyao Wang, Partab Rai, Xiaoli Wang, Kan Sun

Get full text

Omega-3 Status and the Relationship between Plasma Asymmetric Dimethylarginine and Risk of Myocardial Infarction in Patients with Suspected Coronary Artery Disease by Heidi Borgeraas, Elin Strand, Eva Ringdal Pedersen, Jutta Dierkes, Per Magne Ueland, Reinhard Seifert, Eirik Rebnord Wilberg, Pavol Bohov, Rolf K. Berge, Dennis W. T. Nilsen, Ottar Nygård

“…We sought to examine if an association between plasma ADMA and risk of acute myocardial infarction (AMI) was modified by serum n-3 PUFA status. Methods. The cohort included 1364 patients who underwent coronary angiography for suspected coronary artery disease in 2000-2001. …”
Get full text

Are adverse childhood experiences scores associated with heroism or villainy? A quantitative observational study of Marvel and DC Cinematic Universe characters. by Julia Wigmore, Bilal Ahmed, Gabriel Joaquino, Elke Jaibeeh Barah, Zahra Upal, Teressa Boring, Marika Lee, Eron Muel, Samantha Perry, Sandra Davidson, Carla Ginn, Carla Ferreira, Twyla Ens, Jennifer Jackson

Get full text

Association of Subjective Cognitive Concerns With Performance on Mobile App–Based Cognitive Assessment in Cognitively Normal Older Adults: Observational Study by Caroline O Nester, Alyssa N De Vito, Sarah Prieto, Zachary J Kunicki, Jennifer Strenger, Karra D Harrington, Nelson Roque, Martin J Sliwinski, Laura A Rabin, Louisa I Thompson

Get full text

J-TAIL-2: A Prospective, Observational Study of Atezolizumab Combined With Carboplatin and Etoposide in Patients With Extensive-Stage SCLC in Japan by Eisaku Miyauchi, MD, PhD, Makoto Nishio, MD, PhD, Kadoaki Ohashi, MD, PhD, Atsushi Osoegawa, MD, PhD, Eiki Kikuchi, MD, PhD, Hideharu Kimura, MD, PhD, Yasushi Goto, MD, PhD, Junichi Shimizu, MD, PhD, Hiroshige Yoshioka, MD, PhD, Ichiro Yoshino, MD, PhD, Toshihiro Misumi, PhD, Nobuyuki Katakami, MD, PhD, Masahide Oki, MD, PhD, Takashi Kijima, MD, PhD, Kenichi Chikamori, MD, PhD, Kazumi Nishino, MD, PhD, Yuki Kobayashi, MS, Asako Miwa, BA, Misa Tanaka, MS, Akihiko Gemma, PhD

“…Methods: J-TAIL-2 was a prospective, multicenter observational study in Japan. Patients with ES-SCLC received atezolizumab plus CE in clinical practice. …”
Get full text

Dental and oral health assessments in the German National Cohort (NAKO) by Stefanie Samietz, Katrin Borof, Katrin Hertrampf, Ghazal Aarabi, Antonio Ciardo, Hannah Finke, Daniel Hagenfeld, Jan Kühnisch, Maurice Rütters, Sebastian-Edgar Baumeister, Stefan Lars Reckelkamm, Ti-Sun Kim, Thomas Kocher, Wolfgang Ahrens, Hermann Brenner, Carina Emmel, Beate Fischer, Amand Führer, Karin Halina Greiser, Jasmin Grischke, Kathrin Günther, Volker Harth, Stefanie Jaskulski, André Karch, Thomas Keil, Yvonne Kemmling, Alexander Kluttig, Lilian Krist, Oliver Kuss, Michael Leitzmann, Claudia Meinke-Franze, Karin B. Michels, Nadia Obi, Anette Peters, Nicole Pischon, Tobias Pischon, Sabine Schipf, Börge Schmidt, Henning Teismann, Stefan Rupf, Birte Holtfreter

“…This extended program was carried out in a subgroup of 20,828 participants, including collection of detailed information on the dental and prosthetic status as well as on periodontal, cariological and functional aspects. …”
Get full text