Risk of aortic aneurysm and dissection following exposure to fluoroquinolones, common antibiotics, and febrile illness using a self-controlled case series study design: Retrospecti... by Ajit A Londhe, Chantal E Holy, James Weaver, Sergio Fonseca, Angelina Villasis, Daniel Fife

“…<h4>Objective</h4>Recent observational studies suggest increased aortic aneurysm or dissection (AAD) risk following fluoroquinolone (FQ) exposure but acknowledge potential for residual bias from unreported patient characteristics. …”
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Socioeconomic position across the life course and falls among middle- and older-aged adults: protocol for a systematic review by Stéphane Cullati, Anita van Zwieten, Catherine Sherrington, Fiona M Blyth, Saman Khalatbari-Soltani, Marcia R Franco, Frerik Smit

“…The search strategy combined MeSH headings and search terms related to SEP, falls, middle- and older-aged adults and observational studies. Cohort, case-control and cross-sectional studies with mean or median participant age of &gt;40 years, which report on the association between at least one socioeconomic indicator across the life course and one fall outcome and are published in peer-reviewed academic journals were included. …”
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Pain Perception of the First Eye versus the Second Eye during Phacoemulsification under Local Anesthesia for Patients Going through Cataract Surgery: A Systematic Review and Meta-A... by Chuying Shi, Jinqiu Yuan, Benny Zee

“…We searched the PubMed, EMBASE, and Cochrane CENTRAL databases for the studies published up to October 5, 2018. Prospective observational studies were included. The meta-analysis was conducted by means of random-effects model and fixed-effects model according to the heterogeneity. …”
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Knowledge, attitudes and practices of healthcare professionals in the management of patients with hypertension and concurrent bronchial asthma: a cross-sectional study in the Yello... by Yang Yang, Wenwen Xu, Fei Yu, Xiaohong Yan, Xingbin Ma, Jinxiang Gao

“…The reporting of this study followed the Strengthening the Reporting of Observational Studies in Epidemiology checklist.Setting From 30 March to 15 April 2024 at 66 various level hospitals and community health service centres.Participants Physicians and nurses specialising in clinical internal medicine, each with over 2 years of practice and who provided informed consent.Primary and secondary outcome measures The demographic characteristics of the healthcare professionals and their KAP towards the Management of Patients with Hypertension and Concurrent Bronchial Asthma were collected using a self-administered questionnaire. …”
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The effect of cheese intake on osteoarthritis: a Mendelian randomization study by Song Wen, Zehan Huang, Bin Zhang, Yuqing Huang

“…Introduction Osteoarthritis (OA) is a debilitating chronic disease with a high prevalence, characterized by progressive degeneration of articular cartilage that leads to joint dysfunction, pain, and disability. Observational studies investigating the link between cheese intake and OA have yielded inconclusive results and may be susceptible to confounding. …”
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Phage therapy in the management of respiratory and pulmonary infections: a systematic review by Patience Sarkodie-Addo, Abdul-Halim Osman, Bill Clinton Aglomasa, Eric S. Donkor

“…Conclusion: Based on recently published data originating mainly from observational studies, PT has shown considerable efficacy and safety in the treatment of LRTIs. …”
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Effect of maternal HIV infection on birth outcomes among HIV positive women in Sub Saharan Africa: a systematic review and meta-analysis by Worku Necho Asferie, Tigabu Munye Aytenew, Amare Kassaw, Habtamu Shimels Hailemeskel, Solomon Demis Kebede, Bosena Tebeje Gashaw, Demewoz Kefale

“…Method A systematic literature searches were done from PubMed, Hinari, Google scholar and online research repositories. All observational studies (January/2012 to January 01/2024) reporting the effects of maternal HIV on birth outcomes among HIV positive women in Sub Saharan Africa were included. …”
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Benefits and Risks of Clopidogrel vs. Aspirin Monotherapy after Recent Ischemic Stroke: A Systematic Review and Meta-Analysis by Maurizio Paciaroni, Birsen Ince, Bo Hu, Jiann-Shing Jeng, Kursad Kutluk, Liping Liu, Min Lou, Vladimir Parfenov, Ka Sing Lawrence Wong, Babak Zamani, Dara Paek, Jung Min Han, Michael del Aguila, Shalini Girotra

“…PubMed, Embase, and CENTRAL databases were searched from inception to May 2018 to identify clinical trials and observational studies comparing clopidogrel versus aspirin for secondary prevention in patients with recent ischemic stroke within 12 months. …”
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Association of smoking with amyotrophic lateral sclerosis: A systematic review, and meta-analysis, including dose-response analysis by Kihun Kim<sup>+<sup/>, Dai Sik Ko<sup>+<sup/>, Jin-Woo Kim, Dongjun Lee, Eunjeong Son, Hyun-Woo Kim, Tae-Jin Song<sup>+<sup/>, Yun Hak Kim

“…Introduction Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disorder primarily affecting the voluntary motor nervous system. Several observational studies have provided conflicting results regarding the association between smoking and ALS. …”
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Does completion of radical hysterectomy improve oncological outcomes of women with clinical early-stage cervical cancer and intraoperative detection of nodal involvement?: protocol... by Hui Xu, Qing Liu, Yu Xu, Yi Du, Ai Zheng, Cui Hu, Ya Jia, Qianwen Zhang, Yue-Dong He, Shuang-Shuang Cui, Yong Tian, Lin Ran, Fengmei Ke

“…Methods and analysis This protocol is drafted following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses Protocols guidelines, and the proposed study will be conducted in accordance with the standard guidelines of ‘Preferred Reporting Items for Systematic Reviews and Meta-Analyses’ and ‘Meta-analysis of Observational Studies in Epidemiology reporting guideline’. …”
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Optimising Access Surgery in Senior Haemodialysis Patients (OASIS): study protocol for a multicentre randomised controlled trial by Patrick WHE Vriens, Edith M Willigendael, Maarten A Lijkwan, Friedo W Dekker, Chava L Ramspek, Michiel W de Haan, Çaĝdaş Ünlü, Boudewijn DC Heggen, Koen E A van der Bogt, Marc H Hemmelder, Mickaël J C Hiligsmann, Magda M van Loon, Joris I Rotmans, Jan H M Tordoir, Geert Willem H Schurink, Maarten G J Snoeijs, Marijke J Molegraaf, Philippe WM Cuypers, Denise Nio, Cora H Arts, Jacobien C Verhave, Goos D Laverman, Aron S Bode, Marcel C Weijmer, Bas Govaert, Aaltje Y Adema, Gijs MJM Welten, Michel MPJ Reijnen, Marc JH Groeneveld, Hans S Brink, Jeroen B van der Net, Arno Kuijper, Hilde PE Peters, Roos C van Nieuwenhuizen, Rombout R Kruse, Yvonne C Schrama, Karina A de Groot, Karima Farhat

“…Introduction Current evidence on vascular access strategies for haemodialysis patients is based on observational studies that are at high risk of selection bias. …”
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Risk of stroke associated with proton pump inhibitor use among individuals with and without pre-existing cardiovascular diseases: a systematic review and meta-analysis by Muhammed Shabil, Bijaya K. Padhi, Mahalaqua Nazli Khatib, Soumya V. Menon, Mandeep Kaur, Mukesh Kumari, Puneet Sudan, K. Satyam Naidu, Quazi Syed Zahiruddin, Sarvesh Rustagi, Divya Sharma, Mithhil Arora, Rakesh Kumar Sharma, Edward Mawejje, Prakasini Satapathy, Sanjit Sah

“…Meta-analysis of 14 observational studies revealed a slight but non-significant increased stroke risk among patients with prior CVD (pooled HR = 1.222, 95% CI: 0.963 to 1.481, I² = 78%). …”
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Retinal thickness and vascular density changes in Keratoconus: A systematic review and meta-analysis by Hadi Vahedi, Mirsaeed Abdollahi, Reza Moshfeghinia, Shima Emami, Navid Sobhi, Rana Sorkhabi, Ali Jafarizadeh

“…Methods: We conducted a thorough search in PubMed, Scopus, Embase, and Web of Science, encompassing all observational studies from January 1990 to February 2024. …”
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The effects of acute and chronic exercise on immune markers of TH1/TH2 cells in older adults: a systematic review by Thiago Henrique Teodoro, Katerine Palharini Manfrin Costa, Jonato Prestes, José Campanholi, James Navalta, Guilherme Borges Pereira

“…This review investigates the impact of acute and chronic exercise on immune markers of Th1 and Th2 cells in the older adults.MethodsThis study was conducted as a systematic review, following PRISMA guidelines, databases including PubMed, Web of Science, Embase, Science Direct, and Scopus were searched until March 2024, identifying randomized controlled trials and prospective observational studies that examined the effects of acute and chronic exercise on intracellular and surface markers, cytokines, and immunoglobulins in older adults. …”
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Associations between lipid-lowering drugs and urate and gout outcomes: a Mendelian randomization study by Min Liu, Na Yin, Yuhang Zhu, Aili Du, Chunyuan Cai, Pengyuan Leng

“…Potential associations between urate and gout and lipid-lowering drugs have been revealed in observational studies. However, the effects of lipid-lowering drugs on urate and gout remain controversial. …”
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Effect of the gut microbiome in glaucoma risk from the causal perspective by He Chen, Meng Zhou, Zicheng Zhang, Siqi Bao, Jia Qu, Yaxuan Wu, Ronghua Shi

“…Objective Evidence from observational studies has reported possible associations between the gut microbiome (GM) and glaucoma. …”
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Aetiology of vaginal discharge, urethral discharge, and genital ulcer in sub-Saharan Africa: A systematic review and meta-regression. by Julia Michalow, Magdalene K Walters, Olanrewaju Edun, Max Wybrant, Bethan Davies, Tendesayi Kufa, Thabitha Mathega, Sungai T Chabata, Frances M Cowan, Anne Cori, Marie-Claude Boily, Jeffrey W Imai-Eaton

“…<h4>Methods and findings</h4>We searched Embase, MEDLINE, Global Health, Web of Science, and grey literature from inception until December 20, 2023, for observational studies reporting aetiologic diagnoses among symptomatic populations in SSA. …”
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Patient experience and burden of haemolytic disease of the foetus and newborn: a systematic review by P. Maurice, J. McCallion, M. Fitzgibbon, J. N. Barthelmes, W. Karmous, E. J. Hardy, S. A. Mitchell, C. R. Mitchell, J. Lee, W. Noel, Andras Borsi, J. M. Jouannic

“…While the limited evidence indicates that HDFN does confer a significant burden on patients, the review identifies the need for further well-powered and representative observational studies using well-defined outcome measures to aid a greater understanding of the burden and experience of HDFN. …”
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Association between Anemia and Risk of Parkinson Disease by Yao-Chin Wang, Abel Po-Hao Huang, Sheng-Po Yuan, Chu-Ya Huang, Chieh-Chen Wu, Tahmina Nasrin Poly, Suleman Atique, Woon-Man Kung

“…Articles were independently evaluated by two authors. We included observational studies (case-control and cohort) and calculated the risk ratios (RRs) for associated with anemia and PD. …”
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Measuring serious violence perpetration: comparison of police-recorded and self-reported data in a UK cohort by Rosie Cornish, Alison Teyhan, Kate Tilling, John Macleod, Iain Brennan

“…While we have shown that a key advantage of linkage to police records is it enables outcomes to be measured irrespective of study participation, police data undercounts serious violence. Further, observational studies may also underestimate violence perpetration as individuals with police-recorded serious violence are less likely to participate in research. …”
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