Comparative Effectiveness of Darunavir 1,200 mg Daily and Approved Dosing Strategies for Protease Inhibitor-Experienced Patients by James M. Mikula, Chiu-Bin Hsiao, Joshua R. Sawyer, Qing Ma, Gene D. Morse

“…This retrospective observational study included all patients treated with DRV after documented use of another protease inhibitor at an urban immunodeficiency clinic. …”
Get full text

M-Mode in grade 3 dyspneic patients assessment by Ravikanti Karthik, Yerramsetty Venu Sashank, Kumar Ranjith K., Haward Raymond

“…Methods This is a retrospective observational study. The following parameters were taken into consideration: the mitral annular plane systolic excursion (MAPSE), the tricuspid annular plane systolic excursion (TAPSE), and the E-Point to Septal Separation (EPSS) for the admitted patients. …”
Get full text

Incomplete Antenatal Steroid Therapy Can Enhance Outcomes in Preterm Infants with Emergency Conditions by Sebnem Calkavur, Senem Alkan Ozdemir, Ruya Colak, Ezgi Yangin Ergon, Ferit Kulali, Tulin Gokmen Yildirim

“…STUDY DESIGN: This is a prospective, an observational study which includes preterm infants of 32 weeks of gestation and/or ≤1500 grams who were referred to Izmir Dr. …”
Get full text

Acceptable Postvoid Residual Urine Volume after Vaginal Delivery and Its Association with Various Obstetric Parameters by Wen Sze Choe, Beng Kwang Ng, Ixora Kamisan Atan, Pei Shan Lim

“…This was a prospective observational study of women who delivered vaginally in Universiti Kebangsaan Malaysia Medical Centre from March 2017 to September 2017. …”
Get full text

Echocardiographic evaluation of the size of the main pulmonary artery and right pulmonary artery in dogs with pulmonary hypertension by Giovanni Grosso, Rosalba Tognetti, Oriol Domenech, Andrea Della Pina, Federica Marchesotti, Valentina Patata, Tommaso Vezzosi

“…Methods Prospective, multicenter, observational study. The MPA, maximum and minimum RPA diameter were normalized to body weight (MPA_N, RPAmax_N, and RPAmin_N). …”
Get full text

Impact of hydroxyurea on clinical and biological parameters of sickle cell anemia in children in Abidjan by MIREILLE YAYO- AYE, Adia Eusèbe Adjambri, Boidy Kouakou, Rebecca N'guessan-Blao, Louis Missa Adjé, Taïratou Kamagaté, Vincent Yapo, Duni Sawadogo

“…Methods: We conducted a prospective observational study from November 2017 to April 2019 at the at the Yopougon University Hospital. …”
Get full text

The Impact of Baseline Risk Factors on the Incidence of Febrile Neutropenia in Breast Cancer Patients Receiving Chemotherapy with Pegfilgrastim Prophylaxis: A Real-World Data Analy... by Edward Li, Bridgette Kanz Schroader, David Campbell, Kim Campbell, Weijia Wang

“…**Methods:** This was a retrospective observational study in patients with breast cancer (BC) who received myelosuppressive chemotherapy and prophylactic pegfilgrastim identified January 1, 2017-May 31, 2018 from MarketScan® research databases. …”
Get full text

Cardiac Output Measurements in Septic Patients: Comparing the Accuracy of USCOM to PiCCO by Sophia Horster, Hans-Joachim Stemmler, Nina Strecker, Florian Brettner, Andreas Hausmann, Jitske Cnossen, Klaus G. Parhofer, Thomas Nickel, Sandra Geiger

“…We conducted a prospective observational study in a medical but noncardiological ICU of a university hospital. …”
Get full text

Knowledge, Attitude, Awareness, and Practice Regarding Demodex Mites Among the Thai Population by Paichitrojjana A, Paichitrojjana A

“…This study aims to investigate the knowledge, attitude, awareness, and practice regarding Demodex mites in the Thai population and analyze the influencing factors associated with these aspects.Methods: This study is a cross-sectional, analytical, observational study. All participants completed a questionnaire that covered sociodemographic characteristics, knowledge, attitude, awareness, practice regarding Demodex mites, and sources of health information. …”
Get full text

Prognostic factors in transnasal endoscopic surgery for paediatric patients with ossifying fibroma of the paranasal sinuses and skull base by Jingying Ma, Bing Zhou, Qian Huang, Shunjiu Cui, Dingfang Cao

“…Methods This retrospective observational study included 34 patients under 17 years of age who underwent transnasal endoscopic resection of ossifying fibroma of the paranasal sinuses and skull base from 2005 to 2021 at a single tertiary medical centre. …”
Get full text

Dry Eye Disease following Refractive Surgery: A 12-Month Follow-Up of SMILE versus FS-LASIK in High Myopia by Bingjie Wang, Rajeev K. Naidu, Renyuan Chu, Jinhui Dai, Xiaomei Qu, Hao Zhou

“…Prospective, nonrandomised, observational study. Patients. 90 patients undergoing refractive surgery for myopia were included. 47 eyes underwent SMILE and 43 eyes underwent FS-LASIK. …”
Get full text

Clinical and laboratory characteristics of solitary rectal ulcer syndrome: a retrospective analysis of 36 case by Furkan Ali Uygur, Muhammed Emin Göktepe, Gökhan Aydın, Enes Ağırman, Ahmet Cumhur Dülger

“…This retrospective observational study was conducted at Giresun Education and Research Hospital. …”
Get full text

Association of intraprocedural near admission-level blood pressure with functional outcome in stroke patients treated with mechanical thrombectomy by Min Chen, Lukas Daniel Sauer, Mika Herwig, Jessica Jesser, Meinhard Kieser, Arne Potreck, Markus Möhlenbruch, Peter Arthur Ringleb, Silvia Schönenberger

“…Methods We conducted a retrospective observational study at a single center at a university hospital, which included patients from August 2018 to September 2020 suffering from acute ischemic stroke with anterior circulation vessel occlusion and treated with endovascular therapy. …”
Get full text

Investigating the correlation of hip circumference to cardiovascular disease and type‐2 diabetes using Mendelian randomization by Hongtao Liu, Zhaoyu Li, Su Yan, Shaopeng Ming

“…ABSTRACT Objective This study aimed to assess the correlation between hip circumference (HC) and the risk of cardiovascular disease (CVD) and type 2 diabetes mellitus using Mendelian randomization (MR) to overcome observational study limitations. Design MR analysis utilized genetic variation from the MR Base in a two‐sample analysis. …”
Get full text

Characteristics of paediatric burn injuries seen in the tertiary emergency centre, South Africa by Ntsovelo Mugwena, Rule Human, Maria M. Geyser

“…Methods: A retrospective observational study was conducted in a single emergency centre, Kalafong Provincial Tertiary Hospital, from 01 January 2021 to 31 December 2021. …”
Get full text

CAN WE PREDICT INCIPIENT DIABETES MELLITUS IN PATIENTS WITH TRANSFUSION DEPENDENT β-THALASSEMIA (β-TDT) REFERRED WITH A HISTORY OF PREDIABETES? by Vincenzo De Sanctis, Ashraf Soliman, Shahina Daar, Ploutarchos Tzoulis, Christos Kattamis

“…Objective: This retrospective observational study describes the glycemic trajectories and evaluates predictive indices of β-cell function and insulin sensitivity/resistance in β-TDT patients with prediabetes, both in a steady state and during 3-h oral glucose tolerance test (OGTT), in order to identify patients at high risk for incipient diabetes. …”
Get full text

Hypomania, Depression, Euthymia: New Evidence in Parkinson’s Disease by Margherita Canesi, Sara Lavolpe, Viviana Cereda, Alessandra Ranghetti, Roberto Maestri, Gianni Pezzoli, Maria Luisa Rusconi

“…The aim of this cohort observational study was to evaluate whether the episodes of mood alteration could appear in different disease stages and to verify how nonmotor symptoms were led off into different stages. …”
Get full text

Dyslipidaemia in patients with chronic kidney disease – a neglected cardiovascular risk factor by M R Essop, F Seedat, F J Raal

“…A retrospective, cross-sectional observational study of 250 patients with CKD attending the Charlotte Maxeke Johannesburg Academic Hospital renal clinic from 1 July 2019 to 31 July 2020 was carried out. …”
Get full text

Pulse oximeter perfusion index as a new predictor of hypotension following subarachnoid block in lower segment Cesarean section: A prospective randomized study by Ashish Mohan M, Suman Gupta, Kavya Kanjikkal, Vankudoth Bhaskar

“…Materials and Methods: This prospective observational study included 90 parturients, divided into two groups based on baseline PI: Group 1 (PI≤3.5) and Group 2 (PI>3.5). …”
Get full text

Evaluation of the Biomarkers HMGB1 and IL-6 as Predictors of Mortality in Cirrhotic Patients with Acute Kidney Injury by Célio Geraldo de Oliveira Gomes, Marcus Vinicius Melo de Andrade, Ludmila Resende Guedes, Henrique Carvalho Rocha, Roberto Gardone Guimarães, Fernando Antônio Castro Carvalho, Eduardo Garcia Vilela

“…Methods. Prospective, observational study of 25 hospitalised cirrhotic patients with AKI. …”
Get full text