Long-term outcome of a treat-to-target strategy in late-onset rheumatoid arthritis with chronic lung disease: 5-year results of a prospective observational study by Manami Nomura, Takahiko Sugihara, Hiroyuki Baba, Tadashi Hosoya, Mari Kamiya, Tatsuro Ishizaki, Takumi Matsumoto, Kanae Kubo, Fumio Hirano, Masayo Kojima, Nobuyuki Miyasaka, Shinsuke Yasuda, Masayoshi Harigai

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Machine learning models for dementia screening to classify brain amyloid positivity on positron emission tomography using blood markers and demographic characteristics: a retrospective observational study by Noriyuki Kimura, Kotaro Sasaki, Teruaki Masuda, Takuya Ataka, Mariko Matsumoto, Mika Kitamura, Yosuke Nakamura, Etsuro Matsubara

“…Methods This retrospective observational study assessed the classification performance of combinations of demographic characteristics, routine blood test results, and cognitive test scores to classify PET Aβ-positivity using machine learning. …”
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Assessing the predictive value of serum phosphate for short-term mortality in acute-on-chronic liver failure patients: An observational study at a non-transplant tertiary care centre by Rohit S. Wagh, Shamshersingh Chauhan, Mit Shah, Yogesh Bairwa, Motij Dalai, Meghraj Ingle

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Knowledge and understanding of information after taking decision to participate or not in a randomized trial of surgery vs radiotherapy among patients with locally advanced prostate cancer – an observational study by Yvonne Brandberg, Olof Akre, Mia Bergenmar

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Role of C5aR2 in prognosis of patients with acute respiratory distress syndrome through negative modulation of C5a: A prospective observational study by Muhammed Rashid, Sreedharan Nair, Pooja Gopal Poojari, Vijetha Shenoy Belle, Vijayanarayana Kunhikatta, Daniel A. Vaz, Vishal Shanbhag, Viji Pulikkel Chandran, Shravya Chitrapady, Girish Thunga

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Acute kidney injury, the present on admission (POA) indicator and sex disparities: observational study of inpatient real-world data in a Swiss tertiary healthcare system.... by Michael Simon, Sarah N Musy, Karen Triep, Olga Endrich

“…Sex differences were reported.Methods Retrospective observational study. Explorative analysis. Routinely collected health data, 2019 and 2020 (121 757 cases) on the patient history and intensive care treatment duration, comorbidity levels, coded diagnoses, age and sex.Software and statistic: program R, V.4.1.1, SD; median, IQR; prop.test; standardised mean difference.Results The reporting of postadmission diagnoses showed more interhospital transfers, more intensive care stays, higher scores of severity and treatment intensity, more often mechanical ventilation, a higher age, a higher number of diagnoses, a higher complexity level of the related cases and mortality. …”
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Factors affecting arteriovenous access patency after percutaneous transluminal angioplasty in chronic haemodialysis patients under vascular access monitoring and surveillance: a single-centre observational study by Chung-Kuan Wu, Der-Cherng Tarng, Chia-Hsun Lin, Jyh-Gang Leu, Chih-Yu Yang

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Influence of Anti-TNF and Disease Modifying Antirheumatic Drugs Therapy on Pulmonary Forced Vital Capacity Associated to Ankylosing Spondylitis: A 2-Year Follow-Up Observational Study by Alberto Daniel Rocha-Muñoz, Aniel Jessica Leticia Brambila-Tapia, María Guadalupe Zavala-Cerna, José Clemente Vásquez-Jiménez, Liliana Faviola De la Cerda-Trujillo, Mónica Vázquez-Del Mercado, Norma Alejandra Rodriguez-Jimenez, Valeria Díaz-Rizo, Viviana Díaz-González, Ernesto German Cardona-Muñoz, Ingrid Patricia Dávalos-Rodríguez, Mario Salazar-Paramo, Jorge Ivan Gamez-Nava, Arnulfo Hernan Nava-Zavala, Laura Gonzalez-Lopez

“…Methods. In an observational study, we included AS who had FVC% <80% at baseline. …”
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Direct Oral Anticoagulants Versus Vitamin K Antagonists After Mitral Valve Transcatheter Edge‐to‐Edge Repair in Patients With Atrial Fibrillation: A Single‐Center Observational Study by Jan‐Hendrik Schipper, Anne‐Sophie Sommer, Richard Julius Nies, Clemens Metze, Max Maria Meertens, Jonas Wörmann, Sebastian Dittrich, Jan‐Hendrik van den Bruck, Arian Sultan, Jakob Lüker, Daniel Steven, Christopher Hohmann, Roman Pfister, Stephan Baldus, Ingo Eitel, Christian Frerker, Tobias Schmidt

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Two-year trajectory of functional recovery and quality of life in post-intensive care syndrome: a multicenter prospective observational study on mechanically ventilated patients with coronavirus disease-19 by Junji Hatakeyama, Kensuke Nakamura, Shigeaki Inoue, Keibun Liu, Kazuma Yamakawa, Takeshi Nishida, Shinichiro Ohshimo, Satoru Hashimoto, Naoki Kanda, Shotaro Aso, Shinya Suganuma, Shuhei Maruyama, Yoshitaka Ogata, Akira Takasu, Daisuke Kawakami, Hiroaki Shimizu, Katsura Hayakawa, Takeshi Yoshida, Taku Oshima, Tatsuya Fuchigami, Hironori Yawata, Kyoji Oe, Akira Kawauchi, Hidehiro Yamagata, Masahiro Harada, Yuichi Sato, Tomoyuki Nakamura, Kei Sugiki, Takahiro Hakozaki, Satoru Beppu, Masaki Anraku, Noboru Kato, Tomomi Iwashita, Hiroshi Kamijo, Yuichiro Kitagawa, Michio Nagashima, Hirona Nishimaki, Kentaro Tokuda, Osamu Nishida

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Division of the inferior pulmonary ligament during upper lobectomy does not improve postoperative pulmonary function: a systematic review and meta-analysis of observational studies and randomized controlled trials by Boyang Chen, Weifeng Tang, Junhai Chen, Mingqiang Kang, Jinbiao Xie, Wu Wang, Tianbao Yang, Shijie Huang

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Biological and psychosocial factors associated with the persistence of pruritus symptoms: protocol for a prospective, exploratory observational study in Germany (individual project of the Interdisciplinary SOMACROSS Research Unit [RU 5211]) by Sonja Ständer, Stefan W Schneider, Gudrun Schneider, Stefan Kahnert, Manuel Pedro Pereira, Christian Mess, Volker Huck, Konstantin Agelopoulos, Gina Frank

“…We expect that psychosocial factors relevant to the persistence of symptoms such as fatigue and pain may also show associations to CP.Methods and analysis In this prospective, exploratory observational study situated in Germany, three cohorts of 40 patients each with acute exacerbation of atopic dermatitis and chronic atopic dermatitis and 40 CP patients with unaffected skin will be recruited for a comprehensive translational investigation including pruritus-specific and the shared psychosocial assessments of the RU SOMACROSS. …”
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A 2-Year, Phase IV, Multicentre, Observational Study of Ranibizumab 0.5 mg in Patients with Neovascular Age-Related Macular Degeneration in Routine Clinical Practice: The EPICOHORT Study by Sergio Pagliarini, Stephen Beatty, Blandina Lipkova, Eduardo Perez-Salvador Garcia, Stefaan Reynders, Margarita Gekkieva, Abdelkader Si Bouazza, Stefan Pilz

“…This 2-year, multicentre, observational study was conducted to capture real-world early practice and outcomes across Europe, shortly after European licensing of ranibizumab for nAMD. …”
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Positive end-expiratory pressure and risk of postoperative pulmonary complications in patients living at high altitudes and undergoing surgery at low altitudes: a single-centre, retrospective observational study in China by Zhuoning Li, Kaixi Shang, Zongjing Xia, Xiaoli Ye, Chongcong Gong

“…Objectives To examine whether a high positive end-expiratory pressure (PEEP ≥5 cmH2O) has a protective effect on the risk of postoperative pulmonary complications (PPCs) in a cohort of patients living at high altitudes and undergoing general anaesthesia.Design Retrospective, observational study.Setting A tertiary hospital in China.Participants Adult Tibetan patients living at high altitudes (≥3000 m) and who went to the low-altitude plain to undergo non-cardiothoracic surgery under general anaesthesia, from January 2018 to April 2020.Measurements This study included 1905 patients who were divided according to the application of an intraoperative PEEP: low PEEP (&lt;5 cmH2O, including 0 cmH2O) or high PEEP (≥5 cmH2O). …”
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Clinical Observation of Posterior-Chamber Phakic Implantable Collamer Lens V4c Implantation in Myopic Patients with Shallow Anterior Chamber Depth: A Retrospective, Consecutive Observational Study by Juan Yuan, Shuang Wu, Zongli Hu, Chunlin Chen, Shiyang Ye, Jian Ye

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Can screening for degenerative cervical myelopathy (SCREEN-DCM) be effectively undertaken based on signs, symptoms and known risk factors? Rationale and research protocol for a prospective, multicentre, observational study by Benjamin Davies, Mark Kotter, Granit Molliqaj, Enrico Tessitore, Karl Schaller, Teresa Somma, Aria Nouri, Renato Gondar, Joseph S Cheng, Paolo Cappabianca, Alexandre Lavé, Gianpaolo Jannelli, Allan Martin, Justin Virojanapa, Carmen L A Vleggeert-Lankamp, Valerie ter Wengel, Torstein Meling

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Associations between autistic traits and early ear and upper respiratory signs: a prospective observational study of the Avon Longitudinal Study of Parents and Children (ALSPAC) geographically defined childhood population by Amanda Hall, Dheeraj Rai, Jean Golding, Yasmin Iles-Caven, Steven Gregory, Richard Maw

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Multiple Comorbidities, Psychiatric Disorders, Healthcare Resource Utilization and Costs Among Adults with Essential Tremor: A Retrospective Observational Study in a Large US Commercially Insured and Medicare Advantage Population by Dingwei Dai, Ali Samiian, Joaquim Fernandes, Henriette Coetzer

“…**Methods:** This retrospective observational study was conducted using a large US administrative claims database. …”
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SARS-CoV2 pneumonia patients admitted to the ICU: Analysis according to clinical and biological parameters and the extent of lung parenchymal lesions on chest CT scan, a monocentric observational study. by Abed Al Hadi Krisht, Kévin Grapin, Romain Chauvot de Beauchene, Benjamin Bonnet, Lucie Cassagnes, Bertrand Evrard, Mireille Adda, Bertrand Souweine, Claire Dupuis

“…<h4>Design</h4>Retrospective monocentric observational study achieved on a dataset collected prospectively.…”
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Effects of switching from MiniMed™ 640G to 770G on continuous glucose monitoring metrics and DTR‐QOL scores: An observational study of Japanese people with type 1 diabetes mellitus by Toshiki Kogai, Junko Sato, Haruna Yasuda, Tatsuhiro Ayame, Azusa Ozaki, Eri Takagi, Mami Koshibu, Yuya Nishida, Fuki Ikeda, Hirotaka Watada

“…Materials and Methods This was a 52‐week, prospective, observational study. Fifty Japanese people with type 1 diabetes switched from the MiniMed™ 640G to 770G, and we analyzed the continuous glucose monitoring data of 24 subjects who used auto mode throughout the study. …”
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