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Fibrosis in PCLS: comparing TGF-β and fibrotic cocktail
Published 2025-01-01“…Methods PCLS from “healthy” lung tissue of cancer patients undergoing surgery (n = 7) were incubated with TGF-β1, FC or control for 72 h. Gene expression markers for myofibroblasts differentiation, extracellular matrix (ECM), as well as TGF-β receptors were assessed (RT-qPCR). …”
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Extensions of rational modules
Published 2003-01-01“…It was proved by Radford (1973) that if C is right ℱ-Noetherian (which means that every I∈ℱC is finitely generated), then Rat (−) is a radical. …”
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Joint Analysis of Multiple Omics to Describe the Biological Characteristics of Resistant Hypertension
Published 2025-01-01“…The results of intergroup comparisons were as follows: RH versus N: ascorbic acid (Fold Change (FC):0.42, p < 0.01), GSH (FC:0.65, p < 0.05), choline (FC:1.32, p < 0.05), citric acid (FC:0.48, p < 0.001), TfR (FC2.32, p < 0.001), GPX1 (FC:16.02, p < 0.001), EGLN2 (FC:0.76, p < 0.001); RH versus EH: ascorbic acid (FC:0.52, p < 0.05), GSH (FC:0.55, p < 0.05), choline (FC:1.28, p < 0.05), citric acid (FC:0.59, p < 0.001), TfR (FC:1.71, p < 0.001), GPX1 (FC:2.11, p < 0.05), EGLN2 (FC:0.76, p < 0.05). …”
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EGFR-targeting RNase A-cetuximab antibody-drug conjugate induces ROS-mediated apoptosis to overcome drug resistance in KRAS mutant cancer cells
Published 2025-01-01“…The conjugate also disrupted the Nrf2/Keap1 pathway, with a significant upregulation of Keap1 (FC = 3.7, p ≤ 0.01) and downregulation of Nrf2 (FC = 3.3, p < 0.01), highlighting its role in impairing antioxidant defenses and promoting ROS-mediated cytotoxicity. …”
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Immunoinformatic approach to the design of a novel multi-epitope vaccine against Leishmania major fused to human IgG-Fc
Published 2024-12-01“…Vaccine potency was innovatively improved by covalently fusing human IgG1 Fc with multi-epitope protein. To investigate how the MEV-Fc vaccine interacts with Toll-like receptors, molecular docking, multi-scale normal mode analysis simulation, and computational immune simulation were employed to study humoral and cellular immune responses. …”
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Retracted: On the Interlacing Property and the Routh-Hurwitz Criterion
Published 2020-01-01Get full text
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Véronique Dasen, Le Sourire d’Omphale. Maternité et petite enfance dans l’Antiquité
Published 2018-06-01Get full text
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Retracted: On Vertex Degree-Based Topological Indices for Fixed Branching Vertices of Trees
Published 2023-01-01Get full text
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