The Use of a Hybrid Pillar and Its Importance for Aesthetic Rehabilitation and Tissue Stability: A Clinical Report by Guilherme da Gama Ramos, Danilo Lazzari Ciotti, Samuel Rehder Wimmers Ferreira, Maide Rehder Wimmers Ferreira Margarido, Raquel Adriano Dantas, Marina Nottingham Guerreiro

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Monocyte eukaryotic initiation factor 2 signaling differentiates 17-hydroxy-docosahexaenoic acid levels and pain by Peter R.W. Gowler, Asta Arendt-Tranholm, James Turnbull, Rakesh R. Jha, David Onion, Tony Kelly, Afroditi Kouraki, Paul Millns, Sameer Gohir, Susan Franks, David A. Barrett, Ana M. Valdes, Victoria Chapman

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Wnt/GSK‐3β mediates posttranslational modifications of FLYWCH1 to regulate intestinal epithelial function and tumorigenesis in the colon by Sheema Almozyan, Roya Babaei‐Jadidi, Abrar Aljohani, Sepideh Youssefi, William Dalleywater, Prerna Kadam, Bradley Spencer‐Dene, Emad Rakha, Mohammad Ilyas, Abdolrahman Shams Nateri

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The development of a food-group, tree classification method and its use in exploring dietary associations with metabolic dysfunction-associated Steatotic liver disease (MASLD) and... by Amina A. Alawadi, Amrita Vijay, Jane I. Grove, Moira A. Taylor, Guruprasad P. Aithal

“…Methods: This cross-sectional case-control study included 168 MASLD patients and 34 healthy controls from Nottingham (UK). Dietary data were collected using the EPIC-food frequency questionnaire. …”
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The Eczema Bathing Study: Weekly versus daily bathing for people with eczema? Protocol of an online, randomised controlled trial [version 2; peer review: 1 approved, 2 approved wit... by Paul Leighton, Wei Chern Gavin Fong, Ingrid Muller, Laura Howells, Arabella Baker, Eleanor J Mitchell, Eleanor Harrison, Leila Thuma, Yimin Jiang, Lucy Bradshaw, Alan Montgomery, Fiona Cowdel, Matthew J Ridd, Jane Ravenscroft, Reiko J Tanaka, Miriam Santer, Richard Swinden, Nicholas Hilken, Carron Layfield, Richard Dooley, Sophia Collins, Clare Upton, Tracy Owen, Firoza Davies, Devin Patel, Mars Eddis-Finbow, Hywel C Williams, Goldie Putrym, Kim S Thomas, Amanda Roberts

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SLC1A5 is a key regulator of glutamine metabolism and a prognostic marker for aggressive luminal breast cancer by Lutfi H. Alfarsi, Rokaya El Ansari, Busra Erkan, Ali Fakroun, Madeleine L. Craze, Mohammed A. Aleskandarany, Kiu Wai Cheng, Ian O. Ellis, Emad A. Rakha, Andrew R. Green

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Direct targeting of risk factors significantly increases the detection of liver cirrhosis in primary care: a cross-sectional diagnostic study utilising transient elastography by Guruprasad P Aithal, Indra Neil Guha, Stephen D Ryder, Emilie A Wilkes, David J Harman, Martin W James, Matthew Jelpke, Dominic S Ottey, Timothy R Card

“…Objectives To assess the feasibility of a novel diagnostic algorithm targeting patients with risk factors for chronic liver disease in a community setting.Design Prospective cross-sectional study.Setting Two primary care practices (adult patient population 10 479) in Nottingham, UK.Participants Adult patients (aged 18 years or over) fulfilling one or more selected risk factors for developing chronic liver disease: (1) hazardous alcohol use, (2) type 2 diabetes or (3) persistently elevated alanine aminotransferase (ALT) liver function enzyme with negative serology.Interventions A serial biomarker algorithm, using a simple blood-based marker (aspartate aminotransferase:ALT ratio for hazardous alcohol users, BARD score for other risk groups) and subsequently liver stiffness measurement using transient elastography (TE).Main outcome measures Diagnosis of clinically significant liver disease (defined as liver stiffness ≥8 kPa); definitive diagnosis of liver cirrhosis.Results We identified 920 patients with the defined risk factors of whom 504 patients agreed to undergo investigation. …”
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Determination of the Effects of Camptothecin on Cell Cycling and Apoptosis in Human Leukaemic Cell Lines by Anne Cox, Dawn A. Bradbury, Tracy D. Simmons, Kevin J. Slater, Sharon P. M. Crouch

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Investigation of support structure configurations for selective laser melting of In718 by Yi Nie, Chenlong Xu, Zhongkui Liu, Lihang Yang, Tianqi Li, Yinfeng He

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Biomarkers in Liver Disease: Emerging Methods and Potential Applications by Guruprasad P. Aithal, Neil Guha, Jonathan Fallowfield, Laurent Castera, Andrew P. Jackson

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Determining the Feasibility of Ambulance-Based Randomised Controlled Trials in Patients with Ultra-Acute Stroke: Study Protocol for the “Rapid Intervention with GTN in Hypertensive... by Sandeep Ankolekar, Gillian Sare, Chamila Geeganage, Michael Fuller, Lynn Stokes, Nikola Sprigg, Ruth Parry, A. Niroshan Siriwardena, Philip M. W. Bath

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Extensive Epidermal Skin Loss Secondary to HSV Type One: Neonatal Management Challenges by Rebecca J Calthorpe, Emma Spencer, Jane C Ravenscroft, Ting S Tang, Anna E Martinez, Anjum Deorukhkar

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Efficacy of Adjunctive Antiseptic Lavage Solution in Managing Acute Hip/Knee Prosthetic Joint Infection: A Comparative Study in a Tertiary Revision Center by Jonathan Quinn, FRACS, Bernard H. van Duren, DPhil, FRCS, Reshid Berber, PhD, FRCS, Mark Higgins, FRCS, Hosam E. Matar, FRCS, Andrew R. Manktelow, FRCS, Benjamin V. Bloch, FRCS

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The Acute VertEbRal AugmentaTion (AVERT) study: protocol for a randomised controlled, feasibility trial of spinal medial branch nerve block in hospitalised older patients with vert... by Avril Drummond, Opinder Sahota, Simon Bishop, Dritan Pasku, Apostolos Fakis, Anastasios Bastounis, Chia Wei Tan, Maribel Cameron, Yuriy Arlachov, Michal Czernicki

“…AVERT (Acute VertEbRal AugmentaTion) has received approval by the Health Research Authority (reference IRAS 293210) and is sponsored by Nottingham University Hospitals NHS Trust (reference 21HC001). …”
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Realist inquiry into Maternity care @ a Distance (ARM@DA): realist review protocol by Andrew Booth, Catrin Evans, Stephen Timmons, Helen Spiby, Mark Clowes, Nia Jones, Kerry Evans, Benash Nazmeen, Candice Sunney, Georgia Clancy

“…The review will follow the Realist and Meta-narrative Evidence Synthesis Evolving Standards quality procedures and reporting guidance.Ethics and dissemination Ethical approval has been obtained from the University of Nottingham, Faculty of Medicine and Health Sciences Ethics Committee (FMHS 426–1221). …”
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Resection and Resolution of Bone Marrow Lesions Associated with an Improvement of Pain after Total Knee Replacement: A Novel Case Study Using a 3-Tesla Metal Artefact Reduction MRI... by Thomas Kurien, Robert Kerslake, Brett Haywood, Richard G. Pearson, Brigitte E. Scammell

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A Presentation of Cerebritis Secondary to Granulomatosis with Polyangiitis (Wegener) by James Norman, Ira Pande, Timothy Taylor, Bruno Gran

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Nontraumatic Fracture of the Femoral Condylar Prosthesis in a Total Knee Arthroplasty Leading to Mechanical Failure by Girish N. Swamy, Conal Quah, Elmunzar Bagouri, Nitin P. Badhe

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Uptake, safety and effectiveness of inactivated influenza vaccine in inflammatory bowel disease: a UK-wide study by Abhishek Abhishek, Christian D Mallen, Georgina Nakafero, Matthew J Grainge, Tim Card, Jonathan S Nguyen Van-Tam

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