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941
Evaluation of Dynamic Visual Perception of Riverside Interface in Mountainous Cities from the Perspective of Boating
Published 2025-02-01“…Compared with other viewing methods, boating has more visual advantages for urban interface viewing, which is an important entry point for visual perception research. The research on the dynamic visual perception of urban interface from the perspective of boating can provide a theoretical basis for the control and improvement of visual landscape in mountainous cities.MethodsTaking the riverside interface of the core area of “Two Rivers and Four Banks” in Chongqing as the research object and the cruise line of Liangjianghui as the movement path, this research connects the perception state and spatial characteristics by combining subjective and objective evaluation indicators, and analyzes the underlying logic of the formation of visual perception results. …”
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942
Frailty-adjusted therapy in Transplant Non-Eligible patients with newly diagnosed Multiple Myeloma (FiTNEss (UK-MRA Myeloma XIV Trial)): a study protocol for a randomised phase III...
Published 2022-06-01“…Overall, 740 participants will be registered into the trial to allow 720 and 478 to be randomised at induction and maintenance, respectively.All participants will receive IRD induction with the dosing strategy randomised (1:1) at trial entry. Patients randomised to the standard, reactive arm will commence at the full dose followed by toxicity dependent reactive modifications. …”
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943
Easy, fast and reproducible Stochastic Cellular Automata with chouca
Published 2024-10-01“…By providing an easy and efficient entry point to SCAs, chouca lowers the bar to the use of this class of models for ecologists, managers and general practitioners, providing a leveled-off reproducible platform while opening novel methodological approaches.…”
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944
Pratiques de l’automédication à l’ère de la pandémie COVID-19 dans trois villes de l’Ouest algérien [Practices of self-medication in the COVID-19 pandemic era in three cities of We...
Published 2023-06-01“…The main endpoint was the evaluation ofself-medication practices. Data entry, statistical analysis and editing of results were performed using SPSS software version 20. …”
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945
Foreign Direct Investment and Violent Crimes: Evidence from the Iranian Provinces
Published 2024-12-01“…The results of the second model indicate that the logarithm of GDP per capita has a negative and significant effect on the entry of foreign direct investment. In other words, with the increase of GDP in each province, the amount of foreign direct investment attraction decreases. …”
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946
Elucidating the pharmacological foundations and mechanisms of the Sihai Shuyu formula in treating Graves’ disease through integrated serum metabolomics and network pharmacology wit...
Published 2025-01-01“…Comparative analysis of rat blood samples and SHSY using UPLC-Q-TOF-MS identified 19 blood-entry components, the potential active components of SHSY acting on GD. …”
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947
Pratiques de l’automédication à l’ère de la pandémie COVID-19 dans trois villes de l’Ouest algérien [Practices of self-medication in the COVID-19 pandemic era in three cities of We...
Published 2023-06-01“…The main endpoint was the evaluation ofself-medication practices. Data entry, statistical analysis and editing of results were performed using SPSS software version 20. …”
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948
Transcriptomic profiles of monocyte-derived macrophages exposed to SARS-CoV-2 VOCs reveal immune-evasion escape driven by delta
Published 2025-02-01“…Results After exposure to the 5 VOC of MDM, we initially assessed the presence of the viral SARS-CoV-2 transcripts to confirm viral entry. We then analysed the RNA-Seq data and observed a significant deregulation of both coding and non-coding RNAs. …”
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949
Outcomes in stage IIA versus stage IIB/III in the PALLAS trial [ABCSG-42/AFT-05/PrE0109/BIG-14-13])
Published 2025-01-01“…Patients diagnosed with stage II–III, hormone-receptor-positive, HER2/neu negative breast cancer within 12 months of diagnosis had completed all definitive therapy aside from endocrine therapy (started within 6 months prior to study entry) were eligible. All patients were required to submit a formalin-fixed paraffin-embedded (FFPE) tumor block. …”
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950
La datation des aqueducs lyonnais : un état des lieux
Published 2023-12-01“…As a result, a global analysis was needed.For the Mont d’Or aqueduct, a single excavation conducted around 30 years ago near the entry into Lyon (52-54 rue de la Favorite) brought to light a sherd of Drag 15/17 type terra sigillata pottery in the canal foundation trench. …”
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951
A lipidated peptide derived from the C-terminal tail of the vasopressin 2 receptor shows promise as a new β-arrestin inhibitor
Published 2025-02-01“…As the V2R sequence has been shown to bind β-arrestins with high affinity, we added an N-terminal palmitate residue to allow membrane tethering and cell entry. Here, using BRET2-based biosensors, we demonstrated the ability of ARIP to inhibit agonist-induced β-arrestin recruitment on a series of 7TMRs that includes both stable and transient β-arrestin binders, with efficiencies that depend on receptor type. …”
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952
Development of chimeric Nanobody-Granzyme B functionalized ferritin nanoparticles for precise tumor therapy
Published 2025-03-01“…On the other hand, although direct Granzyme B (GrB) administration can effectively induce tumor cell apoptosis, it lacks universal tumor targeting and efficient cellular entry mechanisms. To address these limitations, we developed a novel nanoparticle-based therapy for the precise targeting of TCL tumor cells and the delivery of GrB. …”
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953
Fálétí’s Philosophical Sensibility
Published 2021-12-01“…Simon Gikandi’s edited Encyclopedia of African Literature (2003) has an entry and other multiple references to Fágúnwà. There is only one reference to Fálétí which is found in the index without any accompanying instance in the work. …”
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954
Editorial
Published 2018-12-01“…They limit political competition between them and try to deter new party entry. Ford’s review overall is positive and she recommends the book to scholars and students as a discussion of the social pressures that parties are exposed to and how they are coping with them. …”
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955
Analytical and Comparative Analysis of Copper Industry Development Programs in Iran
Published 2024-10-01“…According to studies conducted in Iran, the most important challenges in the copper industry include increasing the amount of government salaries and export duties, non-entry of mining and industrial machinery, round-the-clock laws, and fluctuations in exchange rates and inflation. …”
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956
Targeting eEF1A reprograms translation and uncovers broad-spectrum antivirals against cap or m6A protein synthesis routes
Published 2025-02-01“…While plitidepsin inhibits cap- or internal ribosome entry sites (IRES)-mediated translation, its impact on N6-methyladenosine (m6A) translation is limited. …”
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957
Intratumoral pan-ErbB targeted CAR-T for head and neck squamous cell carcinoma: interim analysis of the T4 immunotherapy study
Published 2023-06-01“…Despite rapid progression at trial entry, stabilization of disease (Response Evaluation Criteria in Solid Tumors V.1.1) was observed in 9 of 15 subjects (60%) at 6 weeks post-CAR T-cell administration. …”
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958
Le réseau hydraulique à Pompéi (Italie) de l’époque des Samnites à Auguste (fin ive-fin ier s. av. J.-C.)
Published 2023-12-01“…For their part, wells connected to the nerve centres of the urban road network and to the supply system of thermal buildings would seem to have been in decline, becoming supplementary to the supply provided by the aqueduct pressure system.The collection wells categorically and definitively fell into disuse through the complete obliteration of the reservoir or, if originally in the public sphere, through their assimilation into private property, or even through functional conversion to drains, favoured as it was by the dispersive capacities of the geological subsoil and the considerable depths of the pipe.While this is the information that can be deduced from the analyses conducted on the city of Pompeii’s earliest historical phases, the data that have emerged from the middle and late Samnite periods reveal a change in previous conditions and the adoption of new mechanisms.Between the 3rd and 2nd centuries BC, the introduction of a new urban layout and Pompeii’s entry into Rome’s sphere of influence triggered an urbanistic mutation of the site inspired by the model of the Roman city.Roman-style hydraulic engineering in Pompeii also encouraged the choice of vaulted chamber cisterns, which were often introduced into the city as a complement to the previous storage structures.The chambered cistern type not only reduced the cost of excavating the lava bed, but also made for greater safety in open-air construction and enhanced the static capacity of the walls and cement cover to improve the structural qualities of the cisterns and considerably increase their storage capacity.In particular, the adoption of the sub-type of cistern with multiple, parallel chambers also made it possible, through the principal of the discharge of forces through the vaulted system, to terrace and amplify the spaces available for building.This is what research has shown in the urban construction of Pompeii, which in the course of the 2nd century BC was also focused near the height of the promontory, as attested above all along the southern lava ridge of Regio VIII. …”
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959
Designing a model of effective marketing capabilities based on communication
Published 2025-02-01“…Extended Abstract Introduction Today, with the expansion of the globalization process, the increase in competition, the entry of various domestic and foreign companies, various products and the advancement of technology, it is difficult to maintain customer satisfaction and loyalty; therefore, it seems necessary to take advantage of marketing capabilities and strategies to survive in the competitive scene; because these two factors can provide a good foundation for improving the business performance of the company (Asgarnezhad Nouri et al, 2020). …”
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960
Call for Papers: How attractive are political parties and trade unions to young people?
Published 2018-06-01“…Submission Requirements Submissions will be accepted until 1 July 2018 / 1 February 2019. Entries should be up to 30,000 characters in length (including spaces but excluding bibliography, figures, photographs and tables.) …”
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