Clinical Holistic Medicine: the “New Medicine”, the Multiparadigmatic Physician, and the Medical Record by Søren Ventegodt, Mohammed Morad, Joav Merrick

“…It helps you to reflect deeply, communicate efficiently, provide evidence and safety, and back your self-discipline, never to be carried away by the high speed of modern-day clinical work to give less than the optimal treatment. …”
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Physicians’ and nurses‘ knowledge and attitudes in management of sepsis: An Italian study by Gabriella Nucera, Anna Esposito, Naomi Tagliani, Chiara Jane Baticos, Pietro Marino

“…However, with regard to this latter point, T Student test for sample independent confirmed a significant difference in the average percentages of correct answers between recently (~ 6 months) trained (74 ± 3.4%) nurses (n = 33) and physicians (n = 19) and not recently (> 1 years) or never trained (34.8 ± 7.4%) nurses (n = 99) and physicians (n = 30) (t(10) = 11.72, P = < 0.001). …”
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Nuclear and chloroplast genome variability in leek (Allium porrum L.) by E. A. Dyachenko, T. M. Seredin, M. A. Filyushin

“…The genetic diversity of leeks has never been studied before. Therefore, in this work, we studied the nuclear variability (AFLP) and the chloroplast (nucleotide sequence analysis) genomes using a broad sample. …”
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Impact of corticosteroids on the efficacy of first-line pembrolizumab plus chemotherapy in patients with advanced non-small-cell lung cancer by Amytis Roboubi, Eric Wasielewski, Soraya Bordier, Amélie Turlotte, Geoffrey Pavaut, Arnaud Scherpereel, Alexis Cortot, Clément Gauvain

“…However, the current first-line standard of care usually involves combined chemotherapy (CT) and ICIs, and the effect of SCs on survival under combined CT and ICI has never been studied. Objectives: To investigate the association between SC therapy and survival under CT-ICI in advanced-stage NSCLC patients. …”
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HUSBANDS' PERCEPTIONS AND EXPERIENCES IN CARING FOR WIFE WITH CERVICAL CANCER: A QUALITATIVE PHENOMENOLOGICAL STUDY by Siti Nurul Komariyah, Farida Fitriana, Pudji Lestari

“…These experiences include: all participants' wives experienced bleeding complaints, all participants experienced changes in terms of conjugal sexual relations, most participants had bad concerns about wife disease, the majority of participants never used poly palliative or pain-free services, most participants hoped that administrative services at Dr. …”
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Laboratory diagnosis of H. pylori among dyspeptic patients using Culture and Rapid urease test by Hogir Mohammed Shukri Saadi, Ali Yahya Saeed

“…In this research appear males were less positive for H. pylori than females by urease test and no such statistical association was noticed count on the sex and Helicobacter pylori pathogenicity via culture. Research never noticed any considerable correlation was found between smoking status and patient's residence with H. pylori positive cases by both methods. …”
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Impact of the family doctor system on medication adherence among type 2 diabetes patients in China: a difference-in-differences analysis by Xichen Tong, Haiyan Zou, Luying Zhang, Wen Chen

“…Adult patients with T2DM who continuously registered with family doctors from 2015 to 2019 (n = 18,841) were assigned to the intervention group, while those who never registered during this period (n = 1,429) were classified as the control group. …”
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Study on Management of Blood Transfusion Therapy in Patients with Hereditary Spherocytosis by Shiyue Ma, Lingjian Tang, Chaoli Wu, Hui Tang, Xue Pu, Jinhong Niu

“…The Leu2032Pro mutation identified in patient III-1 is a new missense mutation of the SPTB gene in the Chinese population that has never been reported in literature previously. The presence or absence of acute or chronic infections is a critical deciding factor for the treatment and clinical management of HS patient via blood transfusion. …”
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Gender and age features in adults with congenital heart disease by I.G. Lebid

“…All patients were also divided into those that earlier had surgical/percutaneous interventions and never operated adults with CHD. There were two groups: group 1 – adults after interventions in adulthood (first-time and reoperation), group 2 – adults without any procedures after 18 years. …”
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Allergic conditions and risk of rheumatoid arthritis: a Swedish case–control study by Johan Askling, Lars Klareskog, Lars Alfredsson, Marie Holmqvist, Helga Westerlind, Cynthia S Crowson, Vanessa L Kronzer

“…By contrast, statistically significant associations were observed for animal dander allergy (6% vs 5%, aOR 1.37, 95% CI 1.03 to 1.82), especially in ACPA-positive RA (aOR 1.46 95% CI 1.06 to 2.01) and for atopic dermatitis, in particular for older and ACPA-negative RA (aOR 2.33, 95% CI 1.37 to 3.96 at age 80). Never smokers with allergic rhinitis also had increased risk of developing RA (aOR 1.30, 95% CI 1.00 to 1.68).Conclusion Most common allergies do not increase risk of RA, nor do they protect against RA. …”
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Outcomes of Six-Dose High-Dose Cytarabine as a Salvage Regimen for Patients with Relapsed/Refractory Acute Myeloid Leukemia by Brandi Anders, Lauren Veltri, Abraham S. Kanate, Alexandra Shillingburg, Nilay Shah, Michael Craig, Aaron Cumpston

“…Six-dose high-dose cytarabine (HiDAC-6), commonly used as a consolidation regimen, has never been evaluated as induction therapy. We present a retrospective review of 26 consecutive patients with RR-AML receiving single agent cytarabine 3 g/m2 intravenously every 12 hours on days 1, 3, and 5 for a total of six doses (HiDAC-6). …”
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REFERENCE POINTS OF THE PATHOGENESIS OF THE PHENOMENON OF MODEL FORMATION RISKY REPRODUCTIVE BEHAVIOR TEENAGE GIRLS by Ирина Вячеславовна Бабенко-Сорокопуд

“…Materials and methods The study included adolescents with a gynecological age of at least 2 years who had data on menstrual disorder (MD) and risky sexual activity (RSA) over the past 6 months – group A (n = 257): non-heterosexual (NH), exclusively and predominantly same-sex preference when choosing a potential partner (I, n = 89) and heterosexual (H), who have never had a partner of the same sex (II, n = 168). …”
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Nicotine-free vape liquids containing essential oils of peppermint, lavender, and tangerine: safety and efficacy profiles by Rahmad Aji Prasetya, Djamilah Arifiyana, Zain Budi Syulthoni

“…The result showed that nicotine-free vape liquids containing three EOs did not show any foreign substances that had never been encountered before, which means our product is safer than nicotine-containing vape liquids. …”
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Spicy food intake and overweight/obesity in rural Southwest China: findings from a cross-sectional study by Huali Xiong, Huali Xiong, Peng Zhao, Fengxun Ma, Dayi Tang, Daiqiang Liu

“…Compared with the participants who never consumed spicy food, after adjusting for confounding factors, the adjusted ORs (95% CIs) in frequency of spicy food intake in 1–2 days/week, 3–5 days/week, 6–7 days/week subgroups were 3.985 (1.855–8.560), 4.381 (2.011–9.543), 6.515 (3.101–13.686), respectively. …”
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Real life experience of a screening strategy for latent tuberculosis before treatment with biologicals in indian patients with rheumatic diseases by Anand N Malaviya, Ravita Thakaran, Roopa Rawat, Sanjiv Kapoor, Shriram Garg, Sadhana S Baghel, Christy Messi, Vivekanand, Qamar Zaheer

“…In a total of 2930 “control” patients with the same diseases but never having taken bDMARDs, 18 (0.61%) developed active TB disease. …”
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H.A.R. Gibb ve Onun Arap Dili ve Kur’an Bağlamında İslâm Algısı by Yusuf Seller

“…Basically, when it comes to the arguments related withIslam in any way, he never meant to cast a cloud over his objectivity as ascholar. …”
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Estimating mortality attributable to alcohol or tobacco – a cohort study from Germany by Ulrich John, Hans-Jürgen Rumpf, Monika Hanke, Christian Meyer

“…Aim To analyze whether residents who had disclosed risky alcohol drinking or daily tobacco smoking had a shorter time to death than non-risky drinkers and never daily smokers twenty years later according to the disorder combinations. …”
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Association between weight-adjusted-waist index and serum anti-aging protein α-Klotho in U.S. adults: Evidence from NHANES 2007–2016 by Zujun Wen, Xiang Liu, Tingting Zhang, Junhai Zhang, Zhicong Zou, Shuncheng Jiang, Shusi Li

“…Klotho is known to be one of the root causes of several age-related illnesses. There has never been any prior evidence associating WWI and serum α-Klotho levels. …”
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Efficient chimeric mouse production using a novel embryonic stem cell line by G. V. Kontsevaya, N. A. Feofanova, A. G. Menzorov, I. E. Pristyazhnyuk, A. V. Smirnov, N. R. Battulin, L. A. Gerlinskaya

“…There are several projects dedicated to production of knock-out mouse lines (KOMP Repository, EUCOMM, Lexicon Genetics). Never-theless, there is a need for complex genome modifications, such as large deletions, reporter genes insertion into the 3’ gene regulatory sequence, or site-specific modifications of the genome. …”
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Determinants of Neural Tube Defects among Newborns in Amhara Region, Ethiopia: A Case-Control Study by Abay Woday Tadesse, Ayesheshim Muluneh Kassa, Setognal Birara Aychiluhm

“…However, being supplemented with folic acid or multivitamins before or during pregnancy (AOR=0.37: 95% CI 0.21, 0.65), never having taken any substance during pregnancy (AOR=0.42: 95% CI 0.21, 0.88), and being free from medical illnesses during pregnancy (AOR=0.27: 95% CI 0.11, 0.69) were the protective factors of NTDs. …”
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