Cancer stem-like cells stay in a plastic state ready for tumor evolution by Jiali Xu, Houde Zhang, Zhihao Nie, Wenyou He, Yichao Zhao, Zhenhui Huang, Lin Jia, Zhiye Du, Baotong Zhang, Siyuan Xia

“…However, the phenotypic plasticity of CSCs has never been systematically discussed. Here, we review the distinct intrinsic signaling pathways and unique microenvironmental niches that endow CSC plasticity in solid tumors to adapt to stressful conditions, as well as emerging opportunities for CSC-targeted therapy.…”
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Side-Alternating Vibration Training Improves Muscle Performance in a Patient with Late-Onset Pompe Disease by Aneal Khan, Barbara Ramage, Ion Robu, Laura Benard

“…Side-alternating vibration training (SAVT) was used for 15 weeks in a patient with Late-onset Pompe disease who had never used enzyme replacement or chaperone therapy. …”
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Frequency of Temporomandibular Disorders in Asymptomatic Removable Partial and Complete Denture Wearers by N. Dulčić, V. Jerolimov, J. Pandurić

“…A dogmatic view on occlusion as the main aetiological factor for temporomandibular disorder (TMD) has been present in the literature for a long time, but a direct scientific correlation between occlusal disorders and TMD has never been proven. The purpose of this study was to determine the frequency of TMD signs and tissue-specific diagnoses in a population of 164 asymptomatic participants, 70 removable partial denture wearers and 94 complete denture wearers of an average age of 61.3 years, by means of clinical manual functional analysis. …”
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Isolation and Characterization of 89K Pathogenicity Island-Positive ST-7 Strains of Streptococcus suis Serotype 2 from Healthy Pigs, Northeast China by Shujie Wang, Peng Liu, Chunyu Li, Yafang Tan, Xuehui Cai, Dongsheng Zhou, Yongqiang Jiang

“…Notably, a majority of the serotype 2 isolates belonged to the 89K pathogenicity island-positive ST-7 clone that had historically caused the human STSS outbreaks in the Sichuan and Jiangsu provinces of China, although the human STSS case caused by S. suis had never been reported in northern areas of China. Data presented here indicated that the survey of S. suis should be expanded to or reinforced in the northern areas of China.…”
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Ogrody szkolne we współczesnej szkole. Znak edukacyjnego zacofania, a może jednak postępu? by Ryszard Kowalski, Edward Grott

“…In answering this question, they come down resoundingly in favor of retaining the school garden as an essential and fundamental educational tool, which will never lose its relevance and use in the teaching of science. …”
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Complications in a Young Adult Attributable to a Retained Pediatric Dynamic Hip Screw by Jonathan Bryant, Leroy Butler, Brandon Green, Daniel Krenk

“…He was lost to follow-up and the hardware was never removed. The patient presented to our facility with a periprosthetic subtrochanteric proximal femur fracture just distal to the retained hardware. …”
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Bioabsorbable Suture Anchor Migration to the Acromioclavicular Joint: How Far Can These Implants Go? by Giovanna Medina, Guilherme Garofo, Caio O. D’Elia, Alexandre C. Bitar, Wagner Castropil, Breno Schor

“…What motivated this case report was the unusual location of the anchor, found in the acromioclavicular joint which, to our knowledge, has never been reported so far. A 53-year old male with previous rotator cuff (RC) repair using bioabsorbable suture anchors presented with pain and weakness after 2 years of surgery. …”
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Neuroinvasive Infection from O117:K52:H-Escherichia coli following Acute Pyelonephritis by H. Cromlin, H. Rodriguez-Villalobos, A. Deplano, T. Duprez, P. Hantson

“…The strain was identified as O117:K52:H, a serotype that was until now never associated with acute meningitis or brain abscesses. …”
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Intake of Nutritional Supplements among People Exercising in Gyms in Beirut City by D. El Khoury, S. Antoine-Jonville

“…The use of nutritional supplements among exercisers in gyms has been never investigated in the Middle East. The aim of the current study was to assess the prevalence intake of nutritional supplements and the potential influencing factors among people exercising in gyms in Beirut city. …”
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“I Often Experience a Lack of Trust”: Filipino Migrant Nurses’ Experiences of Coping with Multiple Conflicting Workplace Demands by Thora H. Christiansen, Erla S. Kristjánsdóttir, Unnur Dís Skaptadóttir

“…Performing the role of the ideal migrant, ideal worker, and ideal nurse, who works hard and never complains, is in conflict with the demands of the role of the supportive coworker who stands in solidarity with their fellow Icelandic nurses in the fight for improved wages and working conditions.…”
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Multiple Comorbid Conditions among Middle-Aged and Elderly Hemophilia Patients: Prevalence Estimates and Implications for Future Care by Aroub A. Khleif, Nidra Rodriguez, Deborah Brown, Miguel A. Escobar

“…As a result, persons with hemophilia are reaching an older age and experiencing various age-related health conditions never seen before in this population. Aim. To determine the prevalence of comorbidities among middle-aged and elderly hemophilia A and hemophilia B patients. …”
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Steppe Eagle breeding population surveys in Turkey between 2015 and 2022 by Márton Horváth, Tibor Juhász, István Béres, Cansu Özcan, Burak Tatar, Ömral Ü. Özkoç, Süreyya İsfendiyaroğlu, Matthias Schmidt, Igor V. Karyakin

“…The status of the species in Turkey has never been clear, as historically only two nesting sites were found and documented in the wider area of Tuz Gölü, which were proved to be active only in some years between 1969 and 1980. …”
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THE CAUSES OF POLITICAL INSTABILITY IN THE REPUBLIC OF TURKEY by S. B. Druzhilovsky

“…At the same time the article shows the examples of the undoubted efficiency of one-party governments, however they never get support from the opposition parties, and eventually also fail to effectively and consistently implement their proposed policies. …”
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On a Newton-Type Method for Differential-Algebraic Equations by S. Amat, M. J. Légaz, P. Pedregal

“…In seeking to minimize the error, by using standard descent schemes, the procedure can never get stuck in local minima but will always and steadily decrease the error until getting to the solution sought. …”
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Understanding of Abdominal Compartment Syndrome among Pediatric Healthcare Providers by J. Chiaka Ejike, Jennifer Newcombe, Joanne Baerg, Khaled Bahjri, Mudit Mathur

“…About one-quarter of participants (83/343), had never measured IAP. Conclusion. Twenty-three percent of HCP surveyed were unaware of ACS. …”
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Tax haven as a method for tax optimization in holding structures by Joanna Toborek- Mazur

“… Rapid technological progress and the globalization it has caused have created an excellent environment for business entities, on which they can reach for various legal and economic solutions that will allow them to maximize their profits. Never before in economic history have companies had so many opportunities and tools to operate effectively on every continent. …”
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Emotion Regulation and Impulse Control of Child Victims of Sexual Harassment in Makassar City by Suhayni Syahran Muhamad

“…Child victims of sexual abuse are able to be optimistic and never give up because they have a desire to make their parents happy and reach their dreams in the future. …”
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Investigation into the Presence or Absence of Solid Particles Generated from Thermal Processes in the Aerosol from an Electrically Heated Tobacco Product with and without Filter El... by Teemu Kärkelä, Jean-Christophe Ebinger, Unto Tapper, Olivier Robyr, Tauno Jalanti

“…Published studies have also confirmed the absence of solid particles in these emissions, which may be due to the filter elements between the tobacco portion and the mouthpiece in the EHTP; however, to the best of our knowledge, the role of these filters has never been investigated. Thus, to determine whether solid particles formed in any part of the product during use, we collected the aerosol from an EHTP with and without filter elements under heated and unheated testing conditions. …”
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Comment et pourquoi : proposition d’un modèle d’évaluation des processus de la phase de développement d’interventions ergonomiques by Valérie Albert, Nicole Vézina, Henriette Bilodeau, Fabien Coutarel

“…In such complex interventions, ergonomists carry out numerous actions before specific work modifications are implemented, but these actions are almost never mentioned in evaluation studies. The goal of this article is to present the methodological framework of a process evaluation focussing on the development phase of complex ergonomic interventions, the development phase occurring prior to the implementation of work modifications. …”
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Late Lung Metastasis of a Primary Eccrine Sweat Gland Carcinoma 10 Years after Initial Surgical Treatment: The First Clinical Documentation by R. F. Falkenstern-Ge, S. Bode-Erdmann, G. Ott, M. Wohlleber, M. Kohlhäufl

“…Late pulmonary metastases with a latency of 10 years have never been reported in the literature. This is the first clinical documentation of late lung metastasis from sweat gland carcinoma with a latency period of 10 years.…”
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