Blood Transcriptional Signatures for Disease Progression in a Rat Model of Osteoarthritis by Michał Korostyński, Natalia Małek, Marcin Piechota, Katarzyna Starowicz

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Association of high organochlorine pesticide serum levels with oxidative stress in intestinal metaplasia and gastric cancer by Gholamreza Asadikaram, Mohammad Reza Ashrafi, Sodaif Darvish Moghaddam, Moslem Abolhassani, Fatemeh Bagheri

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High-Fat Diet Augments VPAC1 Receptor-Mediated PACAP Action on the Liver, Inducing LAR Expression and Insulin Resistance by Masanori Nakata, Boyang Zhang, Yifei Yang, Takashi Okada, Norihito Shintani, Hitoshi Hashimoto, Toshihiko Yada

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Volumetric trans-scale imaging of massive quantity of heterogeneous cell populations in centimeter-wide tissue and embryo by Taro Ichimura, Taishi Kakizuka, Yoshitsugu Taniguchi, Satoshi Ejima, Yuki Sato, Keiko Itano, Kaoru Seiriki, Hitoshi Hashimoto, Ko Sugawara, Hiroya Itoga, Shuichi Onami, Takeharu Nagai

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Archaea methanogens are associated with cognitive performance through the shaping of gut microbiota, butyrate and histidine metabolism by Andrea Fumagalli, Anna Castells-Nobau, Dakshat Trivedi, Josep Garre-Olmo, Josep Puig, Rafel Ramos, Lluís Ramió-Torrentà, Vicente Pérez-Brocal, Andrés Moya, Jonathan Swann, Elena Martin-Garcia, Rafael Maldonado, José Manuel Fernández-Real, Jordi Mayneris-Perxachs

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Henoch–Schönlein Purpura (IgA Vasculitis) in Association with Thyrotoxicosis by Mojgan Sanjari, Mohammadreza Shakibi, Moeinadin Safavi

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Effects of new generation triptans – frovatriptan and almotriptan – on hemodynamic parameters in intact male and female rats by Saracheva Kremena, Hrischev Petar, Vasileva Liliya, Topolov Mariyan, Nikolova Julia, Getova Damianka

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Microbial Changes in Subgingival Plaque and Polymicrobial Intracellular Flora in Buccal Cells after Fixed Orthodontic Appliance Therapy: A Preliminary Study by Caterina Montaldo, Matteo Erriu, Francesca Maria Giovanna Pili, Carla Peluffo, Annalisa Nucaro, Germano Orrù, Gloria Denotti

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Determination of Tenacissoside G, Tenacissoside H, and Tenacissoside I in Rat Plasma by UPLC-MS/MS and Their Pharmacokinetics by Fan Chen, Yizhe Ma, Ying Cui, Wanhang Wang, Chenchen Mei, Jingjing Nie, Congcong Wen, Xiuwei Shen, Xuzhao Zhou

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Preventative Effects of Vitamin E on Testicular Damage and Sperm Parameters in the First-Generation Mice Pups due to Pre- and Postnatal Mancozeb Exposure by Esmaeil Saddein, Tahereh Haghpanah, Seyed Noreddin Nematollahi-Mahani, Fatemeh Seyedi, Massood Ezzatabadipour

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The First Workers of the Ant Camponotus obscuripes Are a Different Allometric Morph with Relatively Long Antennae to Communicate with Other Larger Colony Members by Saori Watanabe, Mamoru Terayama, Ryota Kawauchiya, Natsuki Ogusu, Yusuke Fujita, Syunta Mikami, Yuuka Murakami, Eisuke Hasegawa

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Response to the SAMHSA Clinical Advisory: Considerations for Genetic Testing in the Assessment of Substance Use Disorder Risk by Green RP, Blum K, Lewandrowski KU, Gold MS, Lewandrowski AP, Thanos PK, Dennen CA, Baron D, Elman I, Sharafshah A, Modestino EJ, Badgaiyan RD

“…Louis, Missouri, USA; 8Department of Biological Sciences, Dornsife College of Letters, Arts & Sciences, University of Southern California, Los Angeles, CA, USA; 9Behavioral Neuropharmacology and Neuroimaging Laboratory, Department of Pharmacology and Toxicology, Jacobs School of Medicine and Biomedical Sciences, Clinical Research Institute on Addictions, University at Buffalo, Buffalo, NY, USA; 10Department of Family Medicine, Jefferson Health Northeast, Philadelphia, PA, USA; 11Department of Psychiatry, Stanford University School of Medicine, Palo Alto, CA, USA; 12Department of Psychiatry, Harvard University School of Medicine, Cambridge, MA, USA; 13Cellular and Molecular Research Center, School of Medicine, Guilan University of Medical Sciences, Rasht, Iran; 14Brain & Behavior Laboratory, Department of Psychology, Curry College, Milton, Massachusetts, USA; 15Department of Psychiatry, Texas Tech University Health Sciences, School of Medicine, Midland, TX, USACorrespondence: Rajendra D Badgaiyan; Kenneth Blum, Email badgaiyan@gmail.com; drd2gene@gmail.com…”
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Hybrid probe combining MicroLED and neural electrode for precise neural modulation and multi-site recording by Gota Shinohara, Tasuku Kayama, Ayumu Okui, Wataru Oda, Atsushi Nishikawa, Alexander Loesing, Nahoko Kuga, Takuya Sasaki, Hiroto Sekiguchi

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Exploring serum miR-33b as a novel diagnostic marker for hypercholesterolemia and obesity: insights from a pilot case-control study by Yaser Masoumi-Ardakani, Mostafa Eghbalian, Hossein Fallah, Alireza Jafari, Beydolah Shahouzehi

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Using a Two-Steps Clustering and PCA Analysis for Stratified Chronic Non-Cancer Pain Care: A Retrospective Cross-Sectional Study by Peiró AM, Barrachina J, Escorial M, Aguado I, Margarit C, Grimby-Ekman A

“…Ana M Peiró,1,2 Jordi Barrachina,1 Mónica Escorial,1 Isidro Aguado,1 César Margarit,1,3 Anna Grimby-Ekman4 1Neuropharmacology Applied to Pain (NED), Clinical Pharmacology Unit, Alicante Institute for Health and Biomedical Research (ISABIAL), Alicante, 03010, Spain; 2Institute of Bioengineering, University Miguel Hernández, Elche, 03202, Spain; 3Pain Unit, Alicante Department of Health -General Hospital, Alicante, 03010, Spain; 4School of Public Health and Community Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, SwedenCorrespondence: Ana M Peiró, Alicante Institute for Health and Biomedical Research (ISABIAL), Hospital General Universitario Doctor Balmis, c/Pintor Baeza, 12, Alicante, 03010, Spain, Email apeiro@umh.esPurpose: Given the number of people who suffer from chronic pain and the impact on healthcare resources, it is imperative that the people with pain receive an appropriate matched treatment due and stratified care. …”
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Evaluation of Four Multiple Imputation Methods for Handling Missing Binary Outcome Data in the Presence of an Interaction between a Dummy and a Continuous Variable by Sara Javadi, Abbas Bahrampour, Mohammad Mehdi Saber, Behshid Garrusi, Mohammad Reza Baneshi

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Comparison of the two treatment methods in primary hyperparathyroidism due to solitary parathyroid adenoma, Ultrasound-guided percutaneous alcohol ablation vs. parathyroidectomy: a... by Mohammad Eslamian, Babak Tavakoli, Alireza Firouzfar, Alireza Pouramini, Bijan Iraj, Mohsen Kolahdouzan, Marjan Mansourian

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Coupling Bio-Resonance Neurotechnology (BRNT) and Dual Hemispheric Repetitive Transcranial Magnetic Stimulation (rTMS) Reduces Comorbid Major Depressive Disorder (MDD) and Generali... by Sunder K, Makale MT, Makale M, Bodhanapati J, Murphy KT, Dennen CA, Baron D, Thanos PK, Hanna C, Ashford Jnr JW, Lewandrowski KU, Blum K

“…., Del Mar, CA, USA; 7Department of Family Medicine, Jefferson Health Northeast, Philadelphia, PA, USA; 8Division of Addiction Research & Education, Center for Sports, Exercise and Mental Health, Western University Health Sciences, Pomona, CA, USA; 9Behavioral Neuropharmacology and Neuroimaging Laboratory On Addictions (BNNLA), Research Institute On Addictions, Department of Pharmacology and Toxicology, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, Buffalo, NY, USA; 10Department of Molecular Biology, Adelson School of Medicine, Ariel University, Ariel, Israel; 11Stanford University, Psychiatric /Public Mental Health & Population Sciences Palo Alto, Stanford, CA, USA; 12Department of Orthopaedics, Fundación Universitaria Sanitas, Bogotá D.C., Colombia*These authors contributed equally to this workCorrespondence: Kenneth Blum, Email drd2gene@gmail.comAbstract: Major Depressive Disorder (MDD) and Generalized Anxiety Disorder (GAD) are prevalent comorbidities related to a greater likelihood of poor treatment outcomes and prolonged treatment for Reward Deficiency Syndrome (RDS) behaviors. …”
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Evaluation of efficacy and safety of generic tacrolimus (Suprotac®) compared to reference tacrolimus (Prograf^®) in kidney transplantation: a phase IV study by Behzad Einollahi, Mohsen Nafar, Mohammad Javanbakht, Amirhesam Alirezaei, Jalal Azmandian, Abbas Etminan, Mohammad Reza Ardalan, Jalal Etemadi, Roghayeh Akbari, Vahid Pourfarziani, Seyed Sadraddin Rasi Hashemi, Seyed Maryam Rahbar, Shahrzad Shahidi, Javid Safa, Hamid Tayyebi Khosroshahi, Sima Abedi Azar, Shahrzad Ossareh, Abdolamir Atapour, Bahareh Marghoob, Fatemeh Nazemian, Hamidreza Kafi, Araz Sabzvari

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Deciphering In Vitro and In Vivo Pharmacological Properties of Seed and Fruit Extracts of Flacourtia jangomas (Lour.) Raeusch by Farhana Alam Ripa, Fowzia Alam, Fahmida Haque Riya, Yesmin Begum, Sharmin Akter Eti, Nusratun Nahar, Zebunnesa Ahmed, Sabrina Sharmin

“…In both in vivo analgesic tests, SFJC demonstrated substantial (p<0.01) pain inhibition percentages (tail immersion: 49.46%; acetic acid writhing: 66.43%) at a dose of 600 mg/kg. During neuropharmacological screening, all extracts significantly (p<0.01; p<0.05) and dose-dependently decreased the mice’s locomotion activity and motor balance. …”
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