Effect and Mechanism of Catalpol on Behavior in Rats with Post-stroke Depression by WANG Xiangyu, ZHOU Xia, LIU Ju, LIU Fuhong, ZHANG Jiale, SUN Liping, LI Wanbin

“…In the ELISA experiment, compared with the model group, 5-HT and BDNF in the catalpol intervention group were significantly increased on the 4th and 7th day after intervention, and the difference was significant (<italic>P</italic>&lt;0.05); there was no significant difference in NE content in the catalpol intervention group on the 4th and 7th day after intervention (<italic>P</italic>&gt;0.05); compared with the model group, the hippocampal 5-HT and BDNF in the catalpol intervention group increased significantly (<italic>P</italic>&lt;0.05); there was no significant difference in the content of NE in hippocampus between the catalpol intervention group and the model group (<italic>P</italic>&gt;0.05), indicating that catalpol could increase 5-HT and BDNF levels in rats with post-stroke depression, but did not significantly improve NE.ConclusionCatalpol can improve post-stroke depression, promote the recovery of neurological function, regulate the function of central serotonin system and promote the secretion of BDNF.…”
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Do serial troponins predict the need for cardiac evaluation in trauma patients after ground-level fall? by Rachael A Callcut, Alyssa R Bellini, James T Ross, Madelyn Larson, Skyler Pearson, Anamaria J Robles

“…Here, we examine the role of serial troponins in predicting the need for further cardiac workup in trauma patients after sustaining a fall.Methods Retrospective review of all adult trauma activations for ground-level fall from January 1, 2021 to December 31, 2021 in patients who were hemodynamically and neurologically normal at presentation. Outcomes evaluated included need for cardiology consult, admission to cardiology service, outpatient cardiology follow-up, cardiology intervention and in-hospital mortality.Results There were 1555 trauma activations for ground-level fall in the study period. …”
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The interaction network and potential clinical effectiveness of dimensional psychopathology phenotyping based on EMR: a Bayesian network approach by Jianqing Qiu, Ting Zhu, Ke Qin, Wei Zhang

“…Abstract The current DSM-oriented diagnostic paradigm has introduced the issue of heterogeneity, as it fails to account for the identification of the neurological processes underlying mental illnesses, which affects the precision of treatment. …”
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Increasing brain half-life of antibodies by additional binding to myelin oligodendrocyte glycoprotein, a CNS specific protein by Marie-Lynn Cuypers, Tom Jaspers, Jarne Clerckx, Simon Leekens, Christopher Cawthorne, Guy Bormans, Frederik Cleeren, Nick Geukens, Bart De Strooper, Maarten Dewilde

“…Abstract Background Therapeutic antibodies for the treatment of neurological disease show great potential, but their applications are rather limited due to limited brain exposure. …”
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Preventing epileptogenesis by interaction between inositol isomers and proteins by Lia Tsverava, Luka Kharkhelauri, Vincenzo Lagani, Giorgi Gamkrelidze, Veriko Bokuchava, Tamar Kiguradze, Merab Kokaia, Revaz Solomonia

“…Plain Language Summary Epilepsy is a common neurological disorder characterized by spontaneous recurrent seizures and a range of associated comorbidities. …”
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Nature's defense against emerging neurodegenerative threats: Dynamic simulation, PCA, DCCM identified potential plant-based antiviral lead targeting borna disease virus nucleoprote... by Noimul Hasan Siddiquee, Md Ifteker Hossain, Farhana Mansoor Priya, Sakia Binte Azam, Md Enamul Kabir Talukder, Durjoy Barua, Salina Malek, Niloy Saha, Sidratul Muntaha, Ridoy Paul, Israt Jahan Ritu, Farjana Islam Tuly, Abir Hossain

“…The rare zoonotic Borna disease virus (BDV) causes fatal neurological disease in various animals, with a high mortality rate exceeding 90% in central Europe. …”
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Overground robotic exoskeleton vs conventional therapy in inpatient stroke rehabilitation: results from a pragmatic, multicentre implementation programme by Pui Kit Tam, Ning Tang, Nur Shafawati Binte Kamsani, Thian Yong Yap, Ita Coffey-Aladdin, Shi Min Goh, Jean Pei Pei Tan, Yook Cing Lui, Rui Ling Lee, Ramaswamy Suresh, Effie Chew

“…We analysed prospectively collected data from Improving Mobility Via Exoskeleton (IMOVE), a multicentre clinical implementation programme of ORE enrolling participants with various neurological conditions and were given options to choose between 12 sessions of ORE or conventional therapy (control). …”
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Bioinformatics insights into mitochondrial and immune gene regulation in Alzheimer's disease by Tian Meng, Yazhou Zhang, Yuan Ye, Hui Li, Yongsheng He

“…Mitochondrial dysfunction in microglia has also been reported to play an essential role in the pathogenesis of AD and other neurological diseases. Therefore, finding the mitochondrial and immune-related gene (MIRG) signatures in AD can be significant in diagnosing and treating AD. …”
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Video Laryngoscopy for Endotracheal Intubation: A Consideration for Manual In-Line Stabilization Without Cervical Collar Versus Full Immobilization by Aramvanitch K, Leela-Amornsin S, Tienpratarn W, Nuanprom P, Aussavanodom S, Yuksen C, Boonsri S, Boonjarus N, Sanepim S

“…Nevertheless, the removal of the cervical collar for ETI in a prehospital setting may lead to a deterioration in neurological outcomes. This study compares the success rate of ETI utilizing a video laryngoscope (VL) on a manikin, contrasting manual in-line stabilization (MILS) without a cervical hard collar against full immobilization.Methods: A randomized, non-crossover study was conducted involving 56 paramedic students assigned by SNOSE to utilize various box sizes for VL intubation with MILS without a cervical hard collar or full immobilization technique on a manikin. …”
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Variations and anomalies in the structure and branching of lumbosacral spinal nerve roots: a case report and global insights by O. S. Nekhlopochyn, V. V. Verbov, M. M. Leshko, Ye. V. Cheshuk, I. M. Ivanovych, T. A. Malysheva

“…The dissonance between prominent neurological symptoms and relatively minor disc protrusion allows for the potential presence of a root variation/anomaly when planning the lumbar spine discectomy. …”
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AI Chatbots and Cognitive Control: Enhancing Executive Functions Through Chatbot Interactions: A Systematic Review by Pantelis Pergantis, Victoria Bamicha, Charalampos Skianis, Athanasios Drigas

“…In addition, this study included general populations with specific neurological conditions, all peer-reviewed, written in English, and with full-text access. …”
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Histopathologic Progression and Metastatic Relapse Outcomes in Small Cell Neuroendocrine Carcinomas of the Urinary Tract by Mohammad Jad Moussa, Georges C. Tabet, Arlene O. Siefker‐Radtke, Lianchun Xiao, Nathaniel R. Wilson, Jianjun Gao, Christopher J. Logothetis, Petros Grivas, Byron Lee, Amishi Y. Shah, Pavlos Msaouel, Roger Li, Leticia Campos Clemente, Jianping Zhao, Nizar M. Tannir, Ashish M. Kamat, Donna E. Hansel, Charles C. Guo, Matthew T. Campbell, Omar Alhalabi

“…The incidence of brain metastasis is notably higher than in “traditional” urothelial cancer within the first year after surgery, especially if small cell cancer persists, thus necessitating close neurological monitoring during this period.…”
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Evaluation of the Feasibility of Transfusing Leukocyte Depletion Filter–Processed Intraoperative Cell Salvage Blood in Metastatic Spine Tumor Surgery: Protocol for a Non–Randomized... by Naresh Kumar, Si Jian Hui, Renick Lee, Sahil Athia, Joel Yong Hao Tan, Jonathan Jiong Hao Tan

“…Available patient data will be reviewed to determine tumor burden secondary to metastasis and postoperative survival and disease progression, improvement in pain, and neurological and ambulatory status. Data collected will be studied postoperatively at 3, 6, 12, 24, 36, and 48 months or until demise, whichever occurs first. …”
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The prolonged health sequelae “of the COVID-19 pandemic” in sub-Saharan Africa: a systematic review and meta-analysis by Melsew Setegn Alie, Getayeneh Antehunegn Tesema, Getayeneh Antehunegn Tesema, Gossa Fetene Abebe, Desalegn Girma

“…These effects can include brain fog, pulmonary symptoms, sleep disturbances, anxiety, fatigue, and other neurological, psychiatric, respiratory, cardiovascular, and general symptoms. …”
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Myofascial trigger points therapy increases neck mobility and reduces headache pain in migraine patients – pilot study by Maciej Olesiejuk, Małgorzata Chalimoniuk, Tomasz Sacewicz

“…Reduced CS-ROM can further contribute to musculoskeletal strain and neurological discomfort in migraine sufferers. The application of IC-MTrPs therapy is of particular interest because it targets these trigger points, potentially normalizing muscle tone and improving local blood flow, which may alleviate pain and restore mobility. …”
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Botulinum Toxin Injection with Conjunctival Microincision for the Treatment of Acute Acquired Comitant Esotropia and Its Effectiveness by Hongjia Xu, Weifeng Sun, Shuying Dai, Yanyan Cheng, Jing Zhao, Yuan Liu, Juan Wang, Ya’nan Wang, Yu Gao, Huifang Han, Aijun Han

“…All patients completed at least 6 months of follow-up, and the mean follow-up after BTXA injection was 12.3 ± 4.8 months (range, 7–24 months). Neurological evaluation and brain magnetic resonance imaging (MRI) were unremarkable in all patients. …”
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Comparative Analysis of Adverse Drug Reactions Associated with Fluoroquinolones and Other Antibiotics: A Retrospective Pharmacovigilance Study by Alshareef H, Alenzi KA, Albalawi BR, Alanazi RM, Albalawi NS, Alasoufi WS, Alqifari S, Ahmed R, Ali MAS

“…Patients who received FQs were fourfold more likely to experience neurological adverse events (OR 4.15, 95% CI 2.48– 6.93, p < 0.001).Conclusion: The FQs drug class exhibited a higher incidence of ADRs than other ABs. …”
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Adaptive cognitive control in 4 to 7-year-old children and potential effects of school-based yoga-mindfulness interventions: an exploratory study in Italy by Lisa Toffoli, Giulia Stefanelli, Giulia Manca, Fiorella Del Popolo Cristaldi, Gian Marco Duma, Michele Guidi, Francesca Incagli, Luca Sbernini, Luca Sbernini, Vincenza Tarantino, Giovanni Mento, Giovanni Mento

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Research Progress of Nerve Mobilization in Basic and Clinical Rehabilitation by Shuo LUAN, Quanshou LING, Miaoshang ZENG, Anni LIN, Yingping JIANG

“…Despite of insufficient evidence, the NM is proved to be used in the prevention, assessment and treatment of neurological disorders, including stroke, traumatic brain injury and Parkinson's disease. …”
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The impact of COVID-19 on global health journals: an analysis of impact factor and publication trends by Hao Li, Don Eliseo Lucero-Prisno, Jiaxin He, Xinliang Liu, Xinyang Lu, Meiling Zhong, Changli Jia, Zheng Feei Ma

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