Clinical manifestations of COVID-19 infection and its impact on the outcome in children and adolescents with benign and malignant hematological disease in Egypt: a single-center ex... by Fatma Soliman Elsayed Ebeid, Aya Mostafa, Sondos M. Magdy, Haidy Moahmed Abd El Kader, Amal Abdel Azim Lotfy, Nihal Hussien Aly

“…Mortality was associated with abnormal neurological examination in COVID-19-positive patients with underlying hematological disease.…”
Get full text

Self-reports map the landscape of task states derived from brain imaging by Brontë Mckeown, Ian Goodall-Halliwell, Raven Wallace, Louis Chitiz, Bridget Mulholland, Theodoros Karapanagiotidis, Samyogita Hardikar, Will Strawson, Adam Turnbull, Tamara Vanderwal, Nerissa Ho, Hao-Ting Wang, Ting Xu, Michael Milham, Xiuyi Wang, Meichao Zhang, Tirso RJ Gonzalez Alam, Reinder Vos de Wael, Boris Bernhardt, Daniel Margulies, Jeffrey Wammes, Elizabeth Jefferies, Robert Leech, Jonathan Smallwood

Get full text

Neuroprotective Effect of Crocin on Rats with Focal Cerebral Ischemia-Reperfusion Injury Based on TLR4/NF-κB Pathway by LI Xiaolei, ZHU Haisheng, MA Ruijuan, HU Ke, FENG Lina, WANG Xudong

“…After reperfution for 24 h, modified neurological severity score (mNSS) was used to evaluate the neurological deficits; triphenyltetrazolium chloride (TTC) staining method was used to evaluate cerebral infarction rate, and dry-wet method was used to evaluate brain water content; hematoxylin-eosin staining (HE) staining and TUNEL staining were used to observe pathological changes and apoptosis of cortical neurons; ELISA method was used to detect the level of inflammatory factors in brain tissue (TNF-α, IL-1β, IL-6, etc.); western blot was used to detect the expression of toll-like receptor 4 (TLR4), nuclear factor-κB p65 (NF-κB p65), p-NF-κB p65, IκBα, p-IκBα, Cleved Caspase-3, B-lymphoma-2 gene (Bcl-2), Bcl-2-related X protein (Bax).Results(1) Neurological function, cerebral infarction rate and cerebral water content: compared with the sham operation group, the mNSS score, cerebral infarction rate, cerebral water content in the model group increased significantly (<italic>P</italic>&lt;0.05); compared with the model group, the mNSS score, cerebral infarction rate, cerebral water content in the crocin group and the crocin + lipopolysaccharide group decreased significantly (<italic>P</italic>&lt;0.05); compared with the crocin group, the mNSS score, cerebral infarction rate, cerebral water content in the crocin + lipopolysaccharide group increased significantly (<italic>P</italic>&lt;0.05). (2) Pathological changes and apoptosis of cortical neurons: the cortical neurons in the sham operation group showed normal morphology and complete structure; the pathological changes of cortical neurons such as disordered arrangement, decreased number, vacuolar degeneration, hyperchromatic cytoplasmic pyknosis, unclear nuclear membrane boundary, inflammatory cell infiltration were observed in the model group; the pathological changes of cortical neurons in the crocin group were significantly improved. …”
Get full text

Delayed diagnosis of popliteal artery injury after traumatic knee dislocation in Korea: a case report by Chung-Eun Lee, In-Seok Jang, Sang-Yoon Song, Jung-Woo Lim, Kun-Tae Kim

“…This case illustrates that, even if ankle-brachial index >0.9 or equal pedal pulse to the uninjured extremity, serial vascular evaluation is required if there are soft signs such as diminished pulses, neurologic signs, or high-energy damage such as multiple ligament ruptures since delayed diagnosis of artery injury can be the major cause of limb amputation. …”
Get full text

Epilepsy Prediction and Detection Using Attention-CssCDBN with Dual-Task Learning by Weizheng Qiao, Xiaojun Bi, Lu Han, Yulin Zhang

“…Epilepsy is a group of neurological disorders characterized by epileptic seizures, and it affects tens of millions of people worldwide. …”
Get full text

Improving quality and outcomes of extracorporeal cardiopulmonary resuscitation in refractory cardiac arrest: the Phoenix ECPR project by Michael Taylor, Vasileios Panoulas, Jill Smith, Alex Rosenberg, Mark Mason, Ian McGovern, Majid Akhtar, Sachin Mehta, Waqas Akhtar, Anthony McKay, Sumesh Thiruthalil, Orinta Kviatkovske, Donna Hall, Eftychia Galiatsou, Sofia Pinto, Maria Comanici, Emanuele Gerlando, Timothy Pitt, Joe Hughes, Olaf Maunz, Elia Keating, Julia Gangata, Eleanor Ross, Sophie Avetoom, Jane Durrant, Ciara Collins, Anand Jothidasan, Maria Monteagudo-Vela, Jerry Mitchell, Hatem Soliman Aboumarie, Caroline Bullen, Sundeep Kaul, Clara Hernandez Caballero, Ana Hurtado, Nick Lees

“…A comparison of ECPR performed pre and post was undertaken.Results With the institution of the new system, 13 patients were treated with ECPR over 1 year; of which nine (69.2%) survived with good neurological outcomes at 6 months. In the preceding 3 years, there had been 22 cases; of which, two survived (9.1%). …”
Get full text

Finding Neural Biomarkers for Motor Learning and Rehabilitation Using an Explainable Graph Neural Network by J. Han, A. Embs, F. Nardi, S. Haar, A. A. Faisal

“…Human motor learning is a neural process essential for acquiring new motor skills and adapting existing ones, which is fundamental to everyday activities. Neurological disorders such as Parkinson&#x2019;s Disease (PD) and stroke can significantly affect human motor functions. …”
Get full text

Diagnosis and Detection of Alzheimer’s Disease Using Learning Algorithm by Gargi Pant Shukla, Santosh Kumar, Saroj Kumar Pandey, Rohit Agarwal, Neeraj Varshney, Ankit Kumar

“…A dataset was obtained from Alzheimer’s Disease Neurological Initiative (ADNI) and converted from a 4D format to a 2D format. …”
Get full text

Application of Perclose ProGlide closure device in transbrachial endovascular intervention by Peng Zhao, Yao Yao, Quan Yang, Ning Wang, Liang Wang, Qianquan Ma, Wenchao Zhang

“…Two patients in the manual compression group reported long-term numbness around the puncture site, while no similar neurological dysfunction was observed in the ProGlide group (P = 0.243). …”
Get full text

Thoracic vertebral body erosion due to a perianeurysmal outpouching lesion after thoracic endovascular aortic repair: a case report and literature review by Hong Jin Kim, Joonghyun Ahn, Kee-Yong Ha, Dong-Gune Chang

“…Physical examination was notable for tenderness in the upper thoracic region without any neurological deficits. Computed tomography of the aorta and thoracic spine showed bony erosion into the T5–T7 vertebral bodies. …”
Get full text

BMSCs Regulate Astrocytes through TSG-6 to Protect the Blood-Brain Barrier after Subarachnoid Hemorrhage by Yilv Wan, Min Song, Xun Xie, Zhen Chen, Ziyun Gao, Xiang Wu, Rui Huang, Min Chen

“…We performed ELISA, neurological scoring, Evans blue staining, NO measurement, immunofluorescence, BBB permeability, Western blot, HE staining, Nissl staining, and immunohistochemistry to evaluate the effect of BMSCs on astrocytes and BBB. …”
Get full text

Restless Legs Syndrome: A Comprehensive Review of Current Treatment Methods and the Disease's Impact on Quality of Life by Natalie Papachristoforou, Natalia Tekiela, Daria Michałka, Zuzanna Gałuszka, Monika Makar, Tomasz Bartuś, Emilia Bąk, Justyna Głowacka, Aleksandra Kocjan, Radosław Chmiel

“…Introduction and Purpose of Research: Restless Leg Syndrome (RLS) or Willis-Ekbom disease, is a common neurological disorder significantly impacting one’s sleep and quality of life. …”
Get full text

Effect of Simulated Eating Movement Training on Upper Limb Function in Hemiplegic Stroke Patients by Yannan CHEN, Xiaoqiong LIN, Wenxia ZHANG, Cui'e FENG, Jinxiu CHEN

“…The changes of Fugl-Meyer assessment scale (FMA), Barthel Index (BI), clinical neurologic deficit scale (CNDS) about hemiplegic upper limb in the two groups were observed before test, 1 month after test and 3 months after test.Results:FMA score and BI about hemiplegic upper limb in the experimental group were significantly different compared with those in the control group (<italic>P</italic>&lt;0.01) after 1 month and 3 month of test. …”
Get full text

A novel proficiency test to assess the animal diagnostic investigation process in identifying an unknown toxicant by Andriy Tkachenko, Yang Chen, Marissa Petrey, Scott Fritz, Tim Walsh, David Rotstein, Megan R. Miller, Bruce Williams, Michael Dark, Matthew Kmet, Ravinder Reddy, Gregory Tyson, Sarah M. Nemser

“…VDLs received a case description outlining neurological signs in cattle, a digitized brain histology slide, and liver and brain tissue samples for optional chemistry analysis. …”
Get full text

KISTA ARACHNOID EKSTRADURAL by Shinta Qorina, Roni Eka Sahputra

“…Sedangkan terapi pembedahan eksisi kista secara utuh direkomendasikan untuk pasien dengan kerusakan neurologis yang berat, serta dilanjutkan dengan obliterasi pedikel komunikan dan repair watertight defek dural untuk menghambat mekanisme ball-valve. …”
Get full text

Future Guides for Biomarkers for Autism Spectrum Disorders by Mai Mohamed Elhassan Mustafa

“…This review consolidates current knowledge on various types of ASD biomarkers, including genetic markers indicating specific gene mutations and epigenetic modifications, neurological markers identified through advanced imaging and neurophysiological techniques, metabolic disturbances captured through the analysis of specific pathways, immune markers reflecting maternal and fetal interactions, and nutritional markers highlighting dietary influences and deficiencies. …”
Get full text

Astrocytic proteins involved in regulation of the extracellular environment are increased in the Alzheimer's disease middle temporal gyrus by Henry Liu, Adelie Y.S. Tan, Nasim F. Mehrabi, Clinton P. Turner, Maurice A. Curtis, Richard L.M. Faull, Mike Dragunow, Malvindar K. Singh-Bains, Amy M. Smith

“…We have used a high-throughput human brain tissue microarray platform with automated quantitative image analysis to measure protein changes in a large cohort of neurological control and AD cases. We found increased astrocytic glial acidic fibrillary protein (GFAP), AQP-4, GLT-1 and Kir4.1 expression that correlates with advancing Braak stage, increasing amyloid pathology and, to a greater extent, the degree of tau pathology. …”
Get full text

Enhanced bioavailability of Quercetin-loaded niosomal in situ gel for the management of Parkinson’s disease by Abhishek A. Revankar, Archana S. Patil, Reshma Karishetti, Krutuja R. Chougule, Priyanka Patil, Abhijit Salokhe

“…BackgroundParkinson’s disease (PD) is the second most prevalent neurological disorder, characterized by motor symptoms such as tremor and rigidity due to the degeneration of dopaminergic neurons in the substantia nigra. …”
Get full text

Successful Management of Thyrocervical Trunk Aneurysm Ruptured into the Thoracic Cavity After Cesarean Section in Nonstable Patient with Neurofibromatosis Type I by Nikola Mirković, Marko Prokić, Marija Novčić, Miloš Arsenijević, Snežana Sretenović, Dragan Knežević, Vojin Kovačević, Marija Šorak, Olivera Kostić

“…Postoperatively, her left neck pain decreased, after which she had no further neurologic deficits. The patient was discharged 10 days later. …”
Get full text

A Case of Xanthoma of Bilateral Tendoachilles Reconstructed with Fascia Lata Graft X by S Jaikish, Balaji Sambandam

“…Simple excision of tendoachilles xanthoma will do more harm to the patient who is more prone to neurological and mobility-related issues. Fascia lata graft has the advantage of limited donor site morbidity and adequate length.…”
Get full text