Platelet-derived HMGB1 induces NETosis, exacerbating brain damage in the photothrombotic stroke model by Sang-A. Oh, Song-I. Seol, Dashdulam Davaanyam, Seung-Woo Kim, Ja-Kyeong Lee

“…Functional inhibition of HMGB1 by intranasal administration of an HMGB1 A box 4 h post-PTS significantly suppressed NETosis induction, reduced infarct volume, and improved neurological deficits, confirming the pivotal role of HMGB1 in NETosis induction. …”
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Electroacupuncture at Quchi and Zusanli Enhances the Proliferation of Cortex and SVZ-derived Neural Stem Cell in Cerebral Ischemia-Reperfusion Injured Rats Via Activation of Notch1... by Jing TAO, Weilin LIU, Jia HUANG, Xiehua XUE, Shanli YANG, Yi ZHENG, Yunjiao LIN, Xiaoqian YE, Meiqin LIN, Lidian CHEN

“…EA at Quchi and Zusanli of the affected limb for three days and seven days, the neurological deficit, infarct volume as well as the overall behavior of the animals were evaluated. …”
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Esketamine at a Clinical Dose Attenuates Cerebral Ischemia/Reperfusion Injury by Inhibiting AKT Signaling Pathway to Facilitate Microglia M2 Polarization and Autophagy by Gao Y, Li L, Zhao F, Cheng Y, Jin M, Xue FS

“…The expression of biomarkers related to microglial M1 and M2 phenotypes in the ischemic brain tissues was determined by immunofluorescence staining and RT-qPCR, and the expression of proteins associated with autophagy and the AKT signaling pathway in the ischemic brain tissues was assayed by Western blotting.Results: Esketamine alone and esketamine combined with rapamycin alleviated neurological impairment, improved sensorimotor function, decreased cerebral infarct volume, and mitigated tissue injury in the MCAO rats. …”
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Epidemiology and Ecology of Toscana Virus Infection and Its Global Risk Distribution by Xue-Geng Hong, Mei-Qi Zhang, Fang Tang, Si-Hui Song, Jia-Yi Wang, Zhen-Yu Hu, Li-Ming Liu, Xiao-Ai Zhang, Yi Sun, Li-Qun Fang, Wei Liu

“…Toscana virus (TOSV), a member of the <i>Phlebovirus</i> genus transmitted by sandflies, is acknowledged for its capacity to cause neurological infections and is widely distributed across Mediterranean countries. …”
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Peroneal Nerve Palsy Caused by Proximal Fibular Solitary Osteochondroma: Case Report and Literature Review by Takashi Kozu, Masayoshi Machida, Katsuaki Taira, Noboru Oikawa, Naho Nemoto, Kazuyoshi Nakanishi

“…Three months postoperatively, the preoperative neurological deficits were found to be nearly resolved. …”
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The Fractured Self: Exploring Selfhood in the Neuronovel The Echo Maker and the Neuromemoir Brain on Fire by Bonnie Cross

“…This paper will focus on two works: the neuronovel The Echo Maker (2006) by Richard Powers, a fictional account of Mark Schluter who suffers from Capgras Syndrome, that is, a rare neurological condition that results in the patient’s belief that their loved ones have been replaced with exact copies; and the neuromemoir Brain on Fire: My Month of Madness (2012) by Susannah Cahalan, which describes Cahalan’s experiences as she is diagnosed with anti-NMDA receptor encephalitis, a rare auto-immune disease. …”
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Evaluating the Cause of Death in Obese Individuals: A Ten-Year Medical Autopsy Study by Jad Saab, Steven P. Salvatore

“…Obese individuals were statistically more likely to die from pulmonary embolism and liver disease and less likely to die from neurologic diseases and nonischemic heart disease. Conclusion. …”
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Evaluation and fMRI Analysis of Cognitive and Language Impairment of Perinatally Acquired Left Brain Injury by Xiuyuan ZHENG, Fenyan HUANG, Tiebin YAN, Lingjun XIAO, Nan YAN, Xiaofeng LIN, Zhiying LIANG

“…Cognitive psychology ability and neurological function were evaluated by Wechsler Intelligence Scale for Children (WISC), somatosensory evoked potential (SEP), motor evoked potential (MEP), electroencephalogram (EEG), MR+MRA+DTI, and Eysenck personality questionnaire (EPQ).Results:Verbal IQ was a little weaker than performance IQ, the difference was not significant. …”
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Neurotoxicological manifestations among drug abusers admitted to Alexandria poison unit and Al-Mamora hospital: prospective study by Haidy Megahed, Maha Ghanem, Ayman Abdelshafi

“…Data collected included demographics, full history of medications, mental and neurological examinations, and investigations.Results: Among 242 patients, drug abuse spanned both sexes and all age groups. …”
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Effect of Hemin on Brain Alterations and Neuroglobin Expression in Water Immersion Restraint Stressed Rats by Merhan Ragy, Fatma Ali, Maggie M. Ramzy

“…Hemin as HO-1 inducer has been shown to attenuate neuronal injury so the goal of this study was to assess the effect of hemin therapy on the acute stress and how it would modulate neurological outcome. Thirty male albino rats were divided into three groups: control group and stressed group with six-hour water immersion restraint stress (WIRS) and stressed group, treated with hemin, in which each rat received a single intraperitoneal injection of hemin at a dose level of 50 mg/kg body weight at 12 hours before exposure to WIRS. …”
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FREQUENCY OF NEONATAL SEPSIS AMONG NEONATES PRESENTING WITH SEIZURES by Abid Imran, Sijad-Ur- Rehman, Imran Qadir, Kainaat Sheikh, Romana Bibi, Muhammad Idrees

“…All neonates were subjected to detailed clinical examination like general physical, neurological examination and detail systemic examination and complete set of baseline investigations. …”
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Sintilimab for treating progressive multifocal leukoencephalopathy caused by human polyomavirus 2 virus infection following allogeneic hematopoietic cell transplantation: a case re... by Xuelian Jin, Xushu Zhong, Qinyu Liu, Xinchuan Chen

“…She received five courses of 100 mg every 4 weeks with monitoring by magnetic resonance imaging (MRI) and viral load in the cerebrospinal fluid, showing clinical improvement, resolution of neurological symptoms, and reduced viral load. MRI showed initial exacerbation of lesions but significant improvement after five courses of treatment. …”
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Response of host immune system to tick borne encephalitis virus by Iveta Stibraniova, Pavlina Bartikova, Jozef Dzubara

“…Approximately one-third of all human TBEV infections are associated with severe clinical neurological disease. The remaining two-thirds are asymptomatic or present with mild clinical symptoms. …”
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Co-occurrence of Myasthenia Gravis and Multiple Sclerosis: A Case Report by G. Rynkevič, R. Kizlaitienė

“…However, laboratory and imagining findings are helpful in distinguishing both diseases and differentiating them from other neurological conditions. Additionally, there can be obstacles in effective treatment selection for patients with MS and MG coexistence. …”
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Effect of Hepatitis E Virus on the Male Reproductive System: A Review of Current Evidence by Ahmed A. Kotb, Mohamed A. El-Mokhtar, Ibrahim M. Sayed

“…Beyond hepatic pathogenesis, HEV has been proven to cause several extrahepatic manifestations, such as neurological, renal, and hematological manifestations. …”
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Potential effects of induced focal ischemia in the motor cortex of rats undergoing experimental periodontitis by Victória dos Santos Chemelo, Marco Aurelio M. Freire, Leonardo Oliveira Bittencourt, Deborah Ribeiro Frazão, Deiweson Souza-Monteiro, Sabrina C. Cartagenes, Walace Gomes-Leal, Cristiane do Socorro Ferraz Maia, Gabriel S. Rocha, Daniel Falcao, Rafael Rodrigues Lima

“…Our results indicate that the model of comorbidity between ligature-induced experimental periodontitis and focal ischemia was capable of inducing greater neurological impairment and alveolar bone loss in rats, attributable to diminished bone quality, when compared to each condition individually.…”
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Two Novel Mutations Identified in an African-American Child with Chediak-Higashi Syndrome by Kerry Morrone, Yanhua Wang, Marjan Huizing, Elie Sutton, James G. White, William A. Gahl, Karen Moody

“…Chediak-Higashi syndrome (CHS) is a rare, autosomal recessive disorder characterized by oculocutaneous albinism, immunodeficiency, coagulopathy and late-onset, progressive neurological dysfunction. It also has an “accelerated phase” characterized by hemophagocytic lymphohistiocytosis (HLH). …”
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Using cortical organoids to understand the pathogenesis of malformations of cortical development by Kellen D. Winden, Isabel Gisser, Mustafa Sahin

“…Despite advances in understanding these disorders, the underlying developmental pathways that lead to lesion formation and mechanisms through which defects in cortical development cause specific neurological symptoms often remains unclear. One limitation is the difficulty in modeling these disorders, as animal models frequently do not faithfully mirror the human phenotype. …”
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Interleukin-22 Plays a Protective Role by Regulating the JAK2-STAT3 Pathway to Improve Inflammation, Oxidative Stress, and Neuronal Apoptosis following Cerebral Ischemia-Reperfusio... by Yongfei Dong, Chengyun Hu, Chunxia Huang, Jie Gao, Wanxiang Niu, Di Wang, Yang Wang, Chaoshi Niu

“…In the current study, we provided direct evidence that IL-22 treatment decreased infarct size, neurological deficits, and brain water content in mice subjected to cerebral I/R injury. …”
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Functional Properties of Human Stem Cell-Derived Neurons in Health and Disease by Jason P. Weick

“…In order to more accurately assess potential therapies for neurological disorders, multiple strategies have been employed in recent years to produce neuronal populations that accurately represent in vivo regional and transmitter phenotypes. …”
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