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5581
Case Report: Rare cardiovascular characteristics of tuberous sclerosis complex with novel TSC2 variant
Published 2025-01-01“…While cardiovascular involvement is less common than neurological or renal manifestations, it typically presents with cardiac rhabdomyomas (CRs). …”
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5582
Prenatal maternal stress in rats alters the epigenetic and transcriptomic landscape of the maternal-fetal interface across four generations
Published 2025-01-01“…Transgenerational programming mainly involved genes and biological pathways associated with neurological and psychiatric diseases which were linked to maternal-fetal crosstalk facilitated by the placenta. …”
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5583
A Clinical Study of Autologous Bone Marrow Mononuclear Cells for Cerebral Palsy Patients: A New Frontier
Published 2015-01-01“…Cerebral palsy is a nonprogressive heterogeneous group of neurological disorders with a growing rate of prevalence. …”
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5584
Sexual Health in Adult Men with Spina Bifida
Published 2007-01-01“…In SB erectile dysfunction and infertility are related to the level of neurological lesion with the best performance status in those with sacral lesions and intact reflexes. …”
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5585
The Neuroprotective Effect of Cornus mas on Brain Tissue of Wistar Rats
Published 2014-01-01“…Flavonoid derivatives as nonenzymatic antioxidants are important in the pathophysiology of many diseases including neurological disorders (e.g., Alzheimer’s disease) or heart disease. …”
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5586
Targeting Histone Deacetylases: A Novel Approach in Parkinson’s Disease
Published 2015-01-01“…Indeed, it is becoming increasingly evident that chromatin acetylation status can be impaired during the neurological disease conditions. The acetylation and deacetylation of histone proteins are carried out by opposing actions of histone acetyltransferases (HATs) and histone deacetylases (HDACs), respectively. …”
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5587
Functional significance of some common oxytocin receptor SNPs involved in complex human traits
Published 2025-01-01“…Method The impact of four common OXTR SNPs (rs1042778, rs4686302, rs2254298 and rs237887) on OXTR gene expression were tested in human neuroblastoma cell line, SH-SY5Y, a commonly used cell line for neurological disease. SNPs were chosen as having robust evidence for associations with complex human traits after consideration of linkage patterns across OXTR. …”
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5588
Ruminal Acidosis in Feedlot: From Aetiology to Prevention
Published 2014-01-01“…Animals will show ruminal hypotony/atony with hydrorumen and a typical parakeratosis-rumenitis liver abscess complex, associated with a plethora of systemic manifestations such as diarrhea and dehydration, liver abscesses, infections of the lung, the heart, and/or the kidney, and laminitis, as well as neurologic symptoms due to both cerebrocortical necrosis and the direct effect of D-lactate on neurons. …”
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5589
Long Course Hyperbaric Oxygen Stimulates Neurogenesis and Attenuates Inflammation after Ischemic Stroke
Published 2013-01-01“…The results were examined using a behavior test (modified neurological severity score, mNSS) and immunostaining to evaluate the effects of HBO therapy on migration of BMSCs, neurogenesis, and gliosis, and expression of neurotrophic factors was also evaluated. …”
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5590
Acromegaly: Role of Surgery in the Therapeutic Armamentarium
Published 2012-01-01“…Patients may also present arterial hypertension, diabetes mellitus, colonic polyps, cardiomegaly, neurological and endocrine changes secondary to the presence of a GH-secreting tumor in pituitary or extrapituitary origin, or eutopic hypothalamic GHRH hypersecretion and peripheral GHRH hypersecretion. …”
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5591
Exploring environmental factors contributing to Parkinson’s disease in AfrAbian populations
Published 2024-12-01“…Climate change, driven mainly by global warming, is linked to detrimental health impacts, including an increased frequency and intensity of heat waves. Neurological diseases, including neurodegenerative syndromes like Alzheimer’s disease, Parkinson’s disease, and motor neuron illnesses, have been increasingly seen and recorded in the scientific literature. …”
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5592
Nanotherapeutics for Meningitis: Enhancing Drug Delivery Across the Blood-Brain Barrier
Published 2025-01-01“…Recently, bionics has emerged as a next-generation technology in the development of novel ideas from biological principles, structures, and interactions for neurological and neuroinfectious diseases. Despite their potential, more studies are needed to ensure the safety and efficacy of NP-based drug delivery systems focusing on critical aspects such as toxicity, immunogenicity, and pharmacokinetics. …”
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5593
Genetic and molecular mechanisms of hydrocephalus
Published 2025-01-01“…Hydrocephalus is a neurological condition caused by aberrant circulation and/or obstructed cerebrospinal fluid (CSF) flow after cerebral ventricle abnormal dilatation. …”
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5594
The Role of Glial Cells in the Pathophysiology of Epilepsy
Published 2025-01-01“…Epilepsy is a chronic neurological disorder marked by recurrent seizures, significantly impacting individuals worldwide. …”
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5595
Biochemical Factors Modulating Cellular Neurotoxicity of Methylmercury
Published 2011-01-01“…Methylmercury (MeHg), an environmental toxicant primarily found in fish and seafood, poses a dilemma to both consumers and regulatory authorities, given the nutritional benefits of fish consumption versus the possible adverse neurological damage. Several studies have shown that MeHg toxicity is influenced by a number of biochemical factors, such as glutathione (GSH), fatty acids, vitamins, and essential elements, but the cellular mechanisms underlying these complex interactions have not yet been fully elucidated. …”
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5596
A Review of Ecological Factors Associated with the Epidemiology of Wildlife Trypanosomiasis in the Luangwa and Zambezi Valley Ecosystems of Zambia
Published 2012-01-01“…The disease has been associated with neurological disorders in humans. Current conservation strategies by the Zambian government of turning all game reserves into state-protected National Parks (NPs) and game management areas (GMAs) have led to the expansion of the wildlife and tsetse population in the Luangwa and Zambezi valley ecosystem. …”
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5597
Role of astrocytes connexins - pannexins in acute brain injury
Published 2025-01-01“…However, after acute brain injury, astrocytes can change their phenotype and modify the activity of both channels and hemichannels, which can result in the amplification of danger signals, increased mediators of inflammation, and neuronal death, contributing to the expansion of brain damage and neurological deterioration. This is known as secondary brain damage. …”
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5598
Graph Neural Networks in Brain Connectivity Studies: Methods, Challenges, and Future Directions
Published 2024-12-01“…Brain connectivity analysis plays a crucial role in unraveling the complex network dynamics of the human brain, providing insights into cognitive functions, behaviors, and neurological disorders. Traditional graph-theoretical methods, while foundational, often fall short in capturing the high-dimensional and dynamic nature of brain connectivity. …”
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5599
Carotid endarterectomy in the setting of persistent hypoglossal artery
Published 2025-02-01“…The operation proceeded without complications, maintaining normal electroencephalogram readings, and the patient exhibited no focal neurological deficits postoperatively, although transient dysphagia was noted. …”
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5600
Concurrent optoacoustic tomography and magnetic resonance imaging of resting-state functional connectivity in the mouse brain
Published 2024-12-01“…Abstract Resting-state functional connectivity (rsFC) has been essential to elucidate the intricacy of brain organization, further revealing clinical biomarkers of neurological disorders. Although functional magnetic resonance imaging (fMRI) remains a cornerstone in the field of rsFC recordings, its interpretation is often hindered by the convoluted physiological origin of the blood-oxygen-level-dependent (BOLD) contrast affected by multiple factors. …”
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