Structural insights into human topoisomerase 3β DNA and RNA catalysis and nucleic acid gate dynamics by Xi Yang, Xuemin Chen, Wei Yang, Yves Pommier

“…Defects in TOP3B lead to severe neurological diseases. We present a series of cryo-EM structures of human TOP3B with its cofactor TDRD3 during cleavage and rejoining of DNA or RNA, thus elucidating the roles of divalent metal ions and key enzyme residues in each step of the catalytic cycle. …”
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Redefining Onyx HD 500 in the Flow Diversion Era by Richard Tyler Dalyai, Ciro Randazzo, George Ghobrial, L. Fernando Gonzalez, Stavropoula I. Tjoumakaris, Aaron S. Dumont, Robert H. Rosenwasser, Pascal Jabbour

“…Four patients experienced transient neurologic deficits in the immediate postoperative period and one in a delayed fashion. …”
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Pus in the pericardium: a pericardial-oesophageal fistula with cardiac tamponade after ablation for atrial fibrillation by Taha Mansoor, Nahal Massoudi, Anandbir Bath, Matthew Kelly, Santhosh Koshy, Armand Tanase

“…Conclusions: It is essential to maintain a high suspicion of PEF/AEF in patients presenting after AF ablation with suggestive symptoms, such as fever, chest pain/odynophagia, and neurological deficits. CT chest is the most common diagnostic modality and surgical correction is the treatment of choice.…”
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Chronic calcified subdural hematoma masquerading as hemorrhagic extra-axial mass: A case report and brief review of the literature by Musharaf Khan, DO, Subtain Ali, MD, Joe T. Joseph, MD, Sanjay Bhatia, MBBS, MS, MBChB, MBA, FAANS, DABA, Dhairya A. Lakhani, MD

“…Given the mass effect and neurological symptoms, surgical evacuation was performed, and intraoperative findings confirmed a chronic subdural hematoma. …”
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Dysuria, Urinary Retention, and Inguinal Pain as Manifestation of Sacral Bannwarth Syndrome by Josef Finsterer, Johannes Dauth, Kurt Angel, Mateusz Markowicz

“…Extensive urological investigations did not reveal a specific cause, which was why neurogenic bladder dysfunction was suspected. Neurologic exam revealed only mildly reduced tendon reflexes. …”
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Variation of Red Blood Cell Distribution Width and Mean Platelet Volume after Moderate Endurance Exercise by Giuseppe Lippi, Gian Luca Salvagno, Elisa Danese, Cantor Tarperi, Gian Cesare Guidi, Federico Schena

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A multimodal characterization of low-dimensional thalamocortical structural connectivity patterns by Alexandra John, Meike D. Hettwer, H. Lina Schaare, Amin Saberi, Şeyma Bayrak, Bin Wan, Jessica Royer, Boris C. Bernhardt, Sofie L. Valk

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Characterization of novel human endogenous retrovirus structures on chromosomes 6 and 7 by Nicholas Pasternack, Nicholas Pasternack, Ole Paulsen, Avindra Nath

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Efficacy of Surgery Combined with Autologous Bone Marrow Stromal Cell Transplantation for Treatment of Intracerebral Hemorrhage by Jianxin Zhu, Yilei Xiao, Zhongmin Li, Fabin Han, Taiwu Xiao, Zhiti Zhang, Fengyang Geng

“…For transplantation group, BMSCs were injected into the perihemorrhage area in the base ganglia through an intracranial drainage tube 5.5 (3.01–6.89) days after surgery, followed by a second injection into the subarachnoid space through lumbar puncture 4 weeks later. Neurologic impairment and daily activities were assessed with National Institute Stroke Scale (NIHSS), Barthel index, and Rankin scale before transplantation and 6 months and 12 months after transplantation. …”
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Impact of glioma metabolism-related gene ALPK1 on tumor immune heterogeneity and the regulation of the TGF-β pathway by YaoFeng Hu, Sen Qin, RuCui Deng

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Case Report: A rare presentation of rapidly progressive moyamoya disease refractory to unilateral surgical revascularization by Daniel Friel Leach, Srivikram Margam S, Aaron Gustin, Paul J. Gustin, Mohamad N. Jajeh, Yhana C. Chavis, Kristin V. Walker, Joshua S. Bentley

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Retraction Note: Serum melatonin levels and in a sample of Iranian patients with migraine by Mansoureh Togha, Morvarid Noormohammadi, Zeinab Ghorbani, Fariba Karimzadeh, S. Zahra Bathaie

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Granuloma annulare following acetazolamide challenge/rechallenge in a patient with idiopathic intracranial hypertension by Samantha A. Mannala, MS, Lulu L.C.D. Bursztyn, MD

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Spike frequency adaptation in primate lateral prefrontal cortex neurons results from interplay between intrinsic properties and circuit dynamics by Nils A. Koch, Benjamin W. Corrigan, Michael Feyerabend, Roberto A. Gulli, Michelle S. Jimenez-Sosa, Mohamad Abbass, Julia K. Sunstrum, Sara Matovic, Megan Roussy, Rogelio Luna, Samuel A. Mestern, Borna Mahmoudian, Susheel Vijayraghavan, Hiroyuki Igarashi, Kartik S. Pradeepan, William J. Assis, J. Andrew Pruszynski, Shreejoy Tripathy, Jochen F. Staiger, Guillermo Gonzalez-Burgos, Andreas Neef, Stefan Treue, Stefan Everling, Wataru Inoue, Anmar Khadra, Julio C. Martinez-Trujillo

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Cerebral microvascular density, blood-brain barrier permeability, and support for neuroinflammation indicate early aging in a Marfan syndrome mouse model by Tala Curry-Koski, Tala Curry-Koski, Liam P. Curtin, Mitra Esfandiarei, Mitra Esfandiarei, Mitra Esfandiarei, Theresa Currier Thomas, Theresa Currier Thomas, Theresa Currier Thomas, Theresa Currier Thomas

“…This study is crucial for identifying and understanding MFS-associated neurovascular and neurological abnormalities, underscoring the need for research aimed at improving the quality of life and managing pre-mature aging symptoms in MFS and related connective tissue disorders.…”
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Phenotypic Presentation of Children with Joint Hypermobility: Preclinical Signs by Mateus Marino Lamari, Neuseli Marino Lamari, Michael Peres de Medeiros, Gerardo Maria de Araújo Filho, Adriana Barbosa Santos, Matheus Gomes Giacomini, Vitor Roberto Pugliesi Marques, Eny Maria Goloni-Bertollo, Érika Cristina Pavarino

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True Lies: The Double Life of the Nucleotide Excision Repair Factors in Transcription and DNA Repair by Nicolas Le May, Jean-Marc Egly, Frédéric Coin

“…NER defects lead to three genetic disorders that result in predisposition to cancers, accelerated aging, neurological and developmental defects. During NER, more than 30 polypeptides cooperate to recognize, incise, and excise a damaged oligonucleotide from the genomic DNA. …”
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A Western Case of Intravascular Large B-Cell Lymphoma as Unusual Cause of Persistent Fever by Pier Paolo Piccaluga, Stefania Paolini, Cristina Campidelli, Nicola Vianelli, Luigi Bolondi

“…Two variants are currently recognized, respectively, occurring in either Western (mainly characterized by neurological symptoms and skin involvement) or Eastern countries (with hemophagocytic syndrome, bone marrow, spleen, and liver involvement). …”
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Patent Foramen Ovale in Patients with Sickle Cell Disease and Stroke: Case Presentations and Review of the Literature by Sheila Razdan, John J. Strouse, Rakhi Naik, Sophie Lanzkron, Victor Urrutia, Jon R. Resar, Linda M. S. Resar

“…The PFO was not closed, and the patients' neurologic symptoms were stabilized. We review the literature on PFOs and stroke in SCD. …”
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Direct Cost of Parkinson’s Disease: A Real-World Data Study of Second-Line Therapies by Elisa Gomez-Inhiesto, María Teresa Acaiturri-Ayesta, Iker Ustarroz-Aguirre, Diana Camahuali, Maider Urtaran-Laresgoiti, Marisol Basabe-Aldecoa, Roberto Nuño-Solinís, Elena Urizar

“…Parkinson’s disease is one of the main reasons for neurological consultation in Spain. Due to the nature of the disease, it impacts patients, families, and caregivers. …”
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