Miglustat Reverts the Impairment of Synaptic Plasticity in a Mouse Model of NPC Disease by G. D’Arcangelo, D. Grossi, M. Racaniello, A. Cardinale, A. Zaratti, S. Rufini, A. Cutarelli, V. Tancredi, D. Merlo, C. Frank

“…Overall, these data indicate that Miglustat may be effective for treating the neurological deficits associated with NPCD, such as seizures and dementia.…”
Get full text

Aggressive Central Nervous System Relapse after Autologous Stem Cell Transplant in Multiple Myeloma: Case Reports and Literature Review by Rui Bergantim, Juliana Bastos, Maria José Soares, Bruno Carvalho, Pedro Soares, Cristina Marques, Jennifer Costa, José Eduardo Guimarães, Fernanda Trigo

“…Central nervous system (CNS) is a very rare manifestation of the extramedullary disease, accounting for less than 1% of MM on diagnosis and relapse. Neurological symptoms are unspecific and usually attributed to other causes. …”
Get full text

Determining the required level of care for patients with acute bacterial meningitis: case reports and literature review by G. Makarevičius, N. Giedraitienė, A. Klimašauskienė

“…The guidelines designed so far mainly suggest admitting patients to ICU based on their neurological status. However, since neurological condition is not the only factor contributing to the outcomes of bacterial meningitis, over- and undertriage cannot always be avoided. …”
Get full text

The crucial role of 5hmC in neuroprotection and repair after cerebrovascular injury by Yanina Tsenkina

“… Cerebrovascular injuries, such as stroke and other vascular insults to the brain, present significant challenges to neurological function and recovery. Within the complex realm of epigenetic modifications, hydroxymethylation emerges as a crucial factor in orchestrating mechanisms for neuroprotection and repair following such injuries. …”
Get full text

Case Report: PCI of the left coronary artery after salvage operation in a comatose patient with an acute type A aortic dissection by Jan Bidovec, Jan Bidovec, Petar Risteski, Petar Risteski, Barbara E. Stähli, Omer Dzemali, Omer Dzemali, Michael Hofmann, Michael Hofmann, Julia Stehli

“…She was extubated on the fourth postoperative day, with no residual neurological impairment. This case report advocates for the proper management of patients with ATAAD with severe neurological impairment, emphasizing the importance of a robust multidisciplinary approach in their care.…”
Get full text

Remote Cerebellar Hemorrhage after Removal of a Supratentorial Glioma without Perioperative CSF Loss: A Case Report by Takuma Hara, Masahide Matsuda, Shinya Watanabe, Kei Nakai, Tetsuya Yamamoto, Akira Matsumura

“…He presented with severe headache, nausea, and vomiting for a few days, then he developed neurological deterioration including progressive disturbance of consciousness and left hemiparesis. …”
Get full text

A Study on the Inflammatory Response of the Brain in Neurosyphilis by Qiyu Zhang, Jie Ma, Jia Zhou, Hanlin Zhang, Mansheng Li, Huizi Gong, Yujie Wang, Heyi Zheng, Jun Li, Ling Leng

“…Abstract Neurosyphilis (NS) is a clinical condition caused by infection of the central nervous system (CNS) by Treponema pallidum (Tp) that can lead to asymptomatic meningitis and more serious neurological diseases, such as dementia and blindness. …”
Get full text

Vasospasm in Cerebral Inflammation by Michael Eisenhut

“…Vasospasm has been associated with permanent neurological deficits and death in subarachnoid haemorrhage and bacterial meningitis. …”
Get full text

Characterization of Human-Induced Neural Stem Cells and Derivatives following Transplantation into the Central Nervous System of a Nonhuman Primate and Rats by Mengjia Li, Zhengbo Wang, Tianqi Zheng, Tianzhuang Huang, Baoguo Liu, Deqiang Han, Sumei Liu, Bochao Liu, Mo Li, Wei Si, Y. Alex Zhang, Yuyu Niu, Zhiguo Chen

“…The results suggest that iNSCs and derivatives have a potential to be used for the treatment of neurological diseases.…”
Get full text

Recent advances in bio-integrated electrochemical sensors for neuroengineering by Shulin Chen, Tzu-Li Liu, Yizhen Jia, Jinghua Li

“…Detecting and diagnosing neurological diseases in modern healthcare presents substantial challenges that directly impact patient outcomes. …”
Get full text

A case of CDKL5 deficiency disorder with a novel intragenic multi-exonic duplication by Takato Akiba, Shino Shimada, Katsumi Imai, Satoru Takahashi

Get full text

Endovascular treatment of penetrating nail gun injury of the cervical spine and vertebral artery: a case report by Alexei Christodoulides, Scott Mitchell, Bradley N. Bohnstedt

Get full text

Unruptured Cerebral Aneurysms: Evaluation and Management by Norman Ajiboye, Nohra Chalouhi, Robert M. Starke, Mario Zanaty, Rodney Bell

Get full text

Evaluation of Novel Stereotactic Cannula for Stem Cell Transplantation against Central Nervous System Disease by Masahito Kawabori, Aki Tanimori, Shinri Kitta, Hideo Shichinohe, Kiyohiro Houkin

Get full text

A rare case of malignant melanoma presenting as anterior-superior mediastinal mass by Dario Familiari, MD, Silvana Parisi, MD, Rossana Rizzo, MD, Elena Valenti, MD, Flavia Nunnari, MD, Michele Sibilio, MD, Rosario Marando, MD, Giancarlo Pino, MD, Francesco Monaco, MD

“…We present an extremely rare case of primary melanoma presenting as an anterior-superior mediastinal mass in a 65 years-old woman who went to the hospital for neurological symptoms due to unknown metastatic brain melanomas.…”
Get full text

Parkinsonian Symptomatology May Correlate with CT Findings before and after Shunting in Idiopathic Normal Pressure Hydrocephalus by Mitsuaki Ishii, Toshio Kawamata, Ichiro Akiguchi, Hideo Yagi, Yuko Watanabe, Toshiyuki Watanabe, Hideaki Mashimo

Get full text

Progressive Back Pain due to Aspergillus nidulans Vertebral Osteomyelitis in an Immunocompetent Patient: Surgical and Antifungal Management by Mark K. Lyons, Matthew T. Neal, Naresh P. Patel, Holenarasipur R. Vikram

Get full text

Inducible Fgf13 ablation alleviates cardiac fibrosis via regulation of microtubule stability by Wang Cong, Wang Xiangchong, Zhang Yiyi, Mi Yuan, Han Yanxue, Zhi Yaxin, Zhao Ran, Cui Nanqi, Ma Qianli, Zhang Huaxing, Xue Dazhong, Qiao Ruoyang, Han Jiabing, Yu Yulou, Li Jiaxuan, Shaiea Mohammed, Liu Demin, Gu Guoqiang, Wang Chuan

Get full text

Transketolase attenuates the chemotherapy sensitivity of glioma cells by modulating R-loop formation by Minjie Fu, Mengli Zhang, Licheng Zhang, Yuan Feng, Chao Gao, Hao Xu, Jinsen Zhang, Huaichao Zhang, Tianping Peng, Youjun Chu, Yonghe Wu, Pu Wang, Dan Ye, Ying Mao, Wei Hua

Get full text

From non-human to human primates: a translational approach to enhancing resection, safety, and indications in glioma surgery while preserving sensorimotor abilities by Matteo Gambaretti, Matteo Gambaretti, Luca Viganò, Luca Viganò, Matteo Gallo, Giovanni Pratelli, Tommaso Sciortino, Lorenzo Gay, Marco Conti Nibali, Alberto Luigi Gallotti, Alberto Luigi Gallotti, Leonardo Tariciotti, Luca Mattioli, Lorenzo Bello, Lorenzo Bello, Gabriella Cerri, Gabriella Cerri, Marco Rossi, Marco Rossi, Marco Rossi

“…The main goal, and, at the same time, the main challenge, of oncological neurological surgery is to avoid permanent neurological deficit while reaching maximal resection, particularly when the tumor infiltrates the neural network subserving motor functions. …”
Get full text