State-of-the-art gene therapy for inherited retinal disorders by O.I. Orenburkina, A.E. Babushkin

“…The results of GRT for other neurological disorders have been obtained mostly in experimental studies. …”
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Smartphone postural sway and pronator drift tests as measures of neurological disability by Michael Calcagni, Peter Kosa, Bibi Bielekova

“…These tests capture different domains of postural control and motoric dysfunction in healthy volunteers (n = 13) and people with neurological disorders (n = 68 relapsing–remitting multiple sclerosis [MS]; n = 21 secondary progressive MS; n = 23 primary progressive MS; n = 13 other inflammatory neurological diseases; n = 21 non-inflammatory neurological diseases; n = 4 clinically isolated syndrome; n = 1 radiologically isolated syndrome). …”
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Mapping the Gaps: A Scoping Review of Virtual Care Solutions for Caregivers of Children with Chronic Illnesses by Nicole Pope, Kathyrn A. Birnie, Melanie Noel, Justine Dol, Danyu Li, Megan Macneil, Darrel Zientek, Victoria Surry, Jennifer N. Stinson

“…Most virtual care solutions targeted caregivers of children with cancer, neurological disorders, and complex chronic illnesses. Over half were noted at lower levels of stepped care (i.e., self-guided apps and websites), with psychological strategies being predominant (84%). …”
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Liposomal Formulations: A Recent Update by Surendra S. Agrawal, Vrinda Baliga, Vaishali Y. Londhe

“…This review also covers recent preclinical and clinical research showing the therapeutic promise of next-generation liposomal formulations for cancer, infectious diseases, neurological disorders and inflammatory disorders. The transfer of these innovative liposomal formulations from lab to clinical practice involves key difficulties such scalability, manufacturing difficulty, and regulatory limits.…”
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Efficient removal of lead (II) from paint factory wastewater using Noug stalk activated carbon: A sustainable adsorption approach by Getasew Yirdaw

“…Exposure to lead (II) poses serious health risks, including carcinogenic effects, neurological disorders, blood-related complications, and damage to vital organs such as the liver, kidneys, and lungs. …”
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A review of the Bovis Calculus’s intervention mechanism and clinical application in ischemic stroke by Ke Xu, Bowen Deng, Tongtong Jia, Mihong Ren, Hai Chen, Jing Zhang, Jinlin Guo, Yong Li, Jian Wang

“…BackgroundBovis Calculus (BC), also named Niuhuang in Chinese, is utilized as a resuscitation drug in Traditional Chinese Medicine (TCM) for the treatment of neurological disorders. Ischemic stroke (IS) is a significant global public health issue that currently lacks safe and effective therapeutic drugs. …”
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Advances in Stem Cell Therapy for Huntington’s Disease: A Comprehensive Literature Review by Siddharth Shah, Hadeel M. Mansour, Brandon Lucke-Wold

“…Although there is no cure at present, the discovery of the gene causing HD has brought us into a new DNA era and therapeutic advances for several neurological disorders. PubMed was systematically searched using three search strings: ‘“Huntington disease” + “stem cell”’, ‘”Huntington disease” + Mesenchymal stromal cell’, and ‘”Huntington disease” + “induced pluripotent stem cell”’. …”
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Arnold-Chiari Malformation Type II and CYP1B1 Congenital Glaucoma: A Possible Association by Shaikha Aldossari, Amani Al Bakri, Yumna Kamal

“…The main learning message here is that ACM-II patients may present with certain ocular symptoms, including glaucoma-related ones that may mimic neurological disorders. This report brings information that could alert general practitioners, neurologists, and neurosurgeons. …”
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DLK-dependent axonal mitochondrial fission drives degeneration after axotomy by Jorge Gómez-Deza, Matthew Nebiyou, Mor R. Alkaslasi, Francisco M. Nadal-Nicolás, Preethi Somasundaram, Anastasia L. Slavutsky, Wei Li, Michael E. Ward, Trent A. Watkins, Claire E. Le Pichon

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Needs for rehabilitation in China: Estimates based on the Global Burden of Disease Study 1990–2019 by Tian Tian, Lin Zhu, Qingzhen Fu, Shiheng Tan, Yukun Cao, Ding Zhang, Mingxue Wang, Ting Zheng, Lijing Gao, Daria Volontovich, Yongchen Wang, Jinming Zhang, Zhimei Jiang, Hongbin Qiu, Fan Wang, Yashuang Zhao, Rongman Jia

“…The rehabilitation needs of neoplasms, cardiovascular diseases, and neurological disorders are expected to increase significantly from 2019 to 2034, with increases of 102.3%, 88.8% and 73.2%, respectively. …”
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Association of vascular endothelial growth factor B (VEGFВ) gene polymorphisms with intracranial aneurysms by R. I. Sultanova, R. I. Khusainova, E. R. Lebedeva, M. A. Yankina, D. V. Gilev, E. K. Khusnutdinova

“…The average worldwide prevalence of this disease is about 2–5 %, with 50 % of them ending in death or neurological disorders of varying severity, with a high probability of recurrence of hemorrhage during the frst half of the year after rupture. …”
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UNC-10/SYD-2 links kinesin-3 to RAB-3-containing vesicles in the absence of the motor's PH domain by Odvogmed Bayansan, Prerana Bhan, Chien-Yu Chang, Syed Nooruzuha Barmaver, Che-Piao Shen, Oliver Ingvar Wagner

“…Kinesin-3 KIF1A (UNC-104 in C. elegans) is the major axonal transporter of synaptic vesicles and mutations in this molecular motor are linked to KIF1A-associated neurological disorders (KAND), encompassing Charcot-Marie-Tooth disease, amyotrophic lateral sclerosis and hereditary spastic paraplegia. …”
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Comparison of specialist ataxia centres with non-specialist services in terms of care access and organisation, health services resource utilisation and costs in Germany using patie... by Julie Vallortigara, Julie Greenfield, Barry Hunt, Holm Graessner, Carola Reinhard, Andreas Nadke, Bart-Jan Schuman, Deborah Hoffman, Steve Morris, Paola Giunti

“…Background: The ataxias are rare complex neurological disorders challenging to diagnose and manage. …”
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Protein palmitoylation is involved in regulating mouse sperm motility via the signals of calcium, protein tyrosine phosphorylation and reactive oxygen species by Yuping Xiong, Chenchen Yi, Haixia Zheng, Ya Ni, Yamei Xue, Kun Li

“…It is also implicated in the pathogenesis of diseases, such as cancer, neurological disorders, inflammation, metabolic disorders, infections, and neurodegenerative diseases. …”
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Alteration of fractional anisotropy in preterm-born individuals: a systematic review and meta-analysis by Le Zhou, Xinghui Liu, Guolin He, Meng Chen, Shuai Zeng, Chuntang Sun

“…Backgroud Neurological disorders are common in preterm (PT) born individuals. …”
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Therapeutic potential of Cinnamomum burmannii bark extract in reducing Malondialdehyde (MDA) levels in MSG-induced wistar rats: a preclinical study by Dina Afrianti, Wahyudi, Ririh Jatmi Wikandari, Rodhi Hartono, Erisa Febriyani, Egy Sunanda Putra

“…Increased consumption of monosodium glutamate (MSG) is associated with various health risks, including cardiovascular and neurological disorders. MSG triggers an increase in reactive oxygen species (ROS), the end product of lipid peroxidation produced when ROS increases is Malondialdehyde (MDA), On the other hand, interleukin 10 (IL-10) reduces the inflammatory effects in infectious conditions that can cause potential tissue damage. …”
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Comorbidities and neurosurgical interventions in a cohort with connective tissue disorders by Ilene S. Ruhoy, Paolo A. Bolognese, Jared S. Rosenblum, Randall A. Dass, Navdeep S. Nayyer, Navdeep S. Nayyer, Jeffrey D. Wood, Jeffrey D. Wood, John B. Biggins, John B. Biggins

“…Some CTDs such as hypermobile Ehlers-Danlos syndrome (hEDS), which is one of the most common, have been associated with neurological disorders requiring surgical intervention. The frequency of these comorbidities in these populations and their subsequent requirement for neurosurgical intervention remains unclear.MethodsBased on our initial experience with this population, we investigated the presentation rates of specific comorbidities and neurosurgical interventions in a cohort of individuals referred to our institution for evaluation and neurosurgical management of issues secondary to diagnosed or suspected CTDs from 2014 to 2023. …”
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Spectral specific standardized low-resolution brain electromagnetic tomography default mode connectivity network and plasticity alterations in left vertebral artery stent patients by Yan Lv, Xiangying He, Eryi Zhao, Yidong Deng, Yingliu Huang, AC Chen, Shixiong Huang, Qi Qin, Tao Liu, Guoqiang Wen

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The functional instrumental test of flexion-extension motion in the radiocarpal joint: reference parameters by Dmitry V. Skvortsov, Danila A. Lobunko, Galina Е. Ivanova

“…The research sample was a group of 15 healthy volunteers (5 males and 10 females aged from 23 to 33 years), not having any joint diseases or neurological disorders. The research was carried out within a period of one year (2022–2023). …”
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The potential of stem cell therapy in Multiple Sclerosis treatment: a review by Sorina Amarculesei, Ava O'Meara Cushen, Cathy Brougham

“…There are currently 371 clinical trials involving mesenchymal stem cells and 462 clinical trials involving adipose derived stem cells, with research focused on skeletal applications, wound healing, and to a lesser degree, haematological and neurological disorders. Although adipose derived stem cells could represent a valuable treatment option for many diseases, several drawbacks to their advancement remain, such as their pro-tumorigenic properties, possible negative alteration of the immune system, and the difficulty in assessing their migration patterns once administered in vivo. …”
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