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381
Resveratrol-Based Carbamates as Selective Butyrylcholinesterase Inhibitors: Design, Synthesis, Computational Study and Biometal Complexation Capability
Published 2025-01-01“…Based on the obtained in silico, experimental and computational results on biological activity in the present work, new carbamates <b>1</b> and <b>7</b> represent potential selective BChE inhibitors as new therapeutics for neurological disorders.…”
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382
Novel nonsense mutation in gene CHRNA2 identified by whole-genome sequencing in infant with epilepsy disorder: A case report
Published 2025-01-01“…Epilepsy is one of the most common neurological disorders affecting approximately 50 million people worldwide. …”
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383
Denoising deep brain stimulation pacemaker signals with novel polymer-based nanocomposites: Porous biomaterials for sound absorption
Published 2024-07-01“…Deep brain stimulation (DBS) pacemakers are sophisticated medical devices that deliver electrical signals to targeted areas of the brain via implanted electrodes, effectively regulating abnormal brain activity and relieving symptoms of treatment-resistant neurological disorders. However, proximity to other electromagnetic equipment may introduce additional noise, which can be disruptive to individuals. …”
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384
Chronic Rapamycin Prevents Electrophysiological and Morphological Alterations Produced by Conditional Pten Deletion in Mouse Cortex
Published 2025-01-01“…These findings have potential implications for the treatment of neurological disorders associated with mTOR pathway dysfunction, such as epilepsy and autism.…”
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385
Chemicals That Disrupt the Endocrine System and Their Effects on Behavior
Published 2024-10-01“…The diseases that are commonly reported due to the action of the above chemicals and daily use items includes neurological disorders, behavioral disorders, metabolic dysfunction leading to obesity or weakness, thyroid dysfunction, reproductive disturbances and several others that can prove fatal and lead to cancer as well. …”
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386
Genomic analysis and replication kinetics of the closely related EHV-1 neuropathogenic 21P40 and abortigenic 97P70 strains
Published 2025-01-01“…Abstract Varicellovirus equidalpha 1, formerly known as Equid alphaherpesvirus 1 (EHV-1), is highly prevalent and can lead to various problems, such as respiratory problems, abortion, neonatal foal death, and neurological disorders. The latter is known as equine herpes myeloencephalopathy (EHM). …”
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387
Apolipoprotein E genotyping variations and their influence on cognitive outcome among idiopathic generalized epileptic patients
Published 2024-12-01“…It is one of the most common neurological disorders, affecting about 50 million people globally. …”
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388
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390
The Rare Large Common Peroneal Nerve’s Schwannoma—A Case Report and Literature Review
Published 2024-01-01“…It is often misdiagnosed with connective tissue tumors or with neurological disorders originating in the spine or disorders of the peroneal nerve. …”
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391
Assessment of the Quality of Life in Patients with Migraine
Published 2023-12-01“…Migraine is one of the most common neurological disorders in the world, affecting around 1.1 billion people worldwide. …”
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392
Assessing the effect of beta-propiolactone inactivation on the antigenicity and immunogenicity of cluster 2.1 duck Tembusu virus
Published 2025-03-01“…Duck Tembusu virus (DTMUV), an emerging avian pathogenic flavivirus, causes severe neurological disorders and acute egg drop syndrome in ducks. …”
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393
DETECTION OF PORCINE CIRCOVIRUS TYPE 3 IN RUSSIAN PIG HOLDINGS
Published 2019-10-01“…A total of 280 samples of biological materials of different types (organs, tissues, stillborn piglets) collected from domestic pigs with respiratory, reproductive and neurological disorders, dermatitis and from emaciated pigs were tested and PCV-3 genome was detected in 11 samples from 9 holdings located in 5 regions of the Russian Federation. …”
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394
Identification of Alzheimer’s Disease Progression Stages Using Topological Measures of Resting-State Functional Connectivity Networks: A Comparative Study
Published 2022-01-01“…Resting-state functional magnetic resonance imaging (rs-fMRI) has been widely employed to examine brain functional connectivity (FC) alterations in various neurological disorders. At present, various computational methods have been proposed to estimate connectivity strength between different brain regions, as the edge weight of FC networks. …”
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395
Akinetopsia: a systematic review on visual motion blindness
Published 2025-02-01“…Aetiologically, most cases were associated with structural neurological conditions such as stroke and neurodegenerative disease, and fewer with intoxications or paroxysmal neurological disorders such as epilepsy. Treatments were mostly successful when they were aimed at the underlying condition, while cases due to organic lesions tended to be therapy-resistant. …”
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396
Histopathological and Biochemical Assessment of Neuroprotective Effects of Sodium Valproate and Lutein on the Pilocarpine Albino Rat Model of Epilepsy
Published 2021-01-01“…Epilepsy is one of the most frequent neurological disorders characterized by an enduring predisposition to generate epileptic seizures. …”
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397
Neuroprotective Effect of Wharton’s Jelly-Derived Mesenchymal Stem Cell-Conditioned Medium (WJMSC-CM) on Diabetes-Associated Cognitive Impairment by Improving Oxidative Stress, Neu...
Published 2023-01-01“…Mesenchymal stem cells have been shown to be potential therapeutic agents for neurological disorders. In the current study, we aimed to examine the effects of Wharton’s jelly-derived mesenchymal stem cell-conditioned medium (WJMSC-CM) on learning and memory, oxidative stress, apoptosis, and histological changes in the hippocampus of diabetic rats. …”
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398
Neuronal Transdifferentiation Potential of Human Mesenchymal Stem Cells from Neonatal and Adult Sources by a Small Molecule Cocktail
Published 2019-01-01“…Human mesenchymal stem cells (MSCs) are good candidates for brain cell replacement strategies and have already been used as adjuvant treatments in neurological disorders. MSCs can be obtained from many different sources, and the present study compares the potential of neuronal transdifferentiation in MSCs from adult and neonatal sources (Wharton’s jelly (WhJ), dental pulp (DP), periodontal ligament (PDL), gingival tissue (GT), dermis (SK), placenta (PLAC), and umbilical cord blood (UCB)) with a protocol previously tested in bone marrow- (BM-) MSCs consisting of a cocktail of six small molecules: I-BET151, CHIR99021, forskolin, RepSox, Y-27632, and dbcAMP (ICFRYA). …”
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399
Non-Redox-Based Electrochemical Detection of Adrenaline: A Simple and Reliable Approach Using Glass Nanopipets
Published 2025-01-01“…The detection of adrenaline (Adr) is essential for monitoring physiological and clinical conditions, including stress response, cardiovascular health, and neurological disorders. We present a novel glass-nanopipet electrode sensor based on a non-redox ion-transfer approach using ion transfer across two immiscible electrolyte solutions (ITIES). …”
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400
Novel role of FTO in regulation of gut–brain communication via Desulfovibrio fairfieldensis-produced hydrogen sulfide under arsenic exposure
Published 2025-12-01“…Collectively, these findings will provide new ideas for understanding the mechanisms of arsenic-induced toxic effects from a gut–brain communication perspective, and will assist the development of explicit intervention strategy via regulation of a new potential target FTO for prevention and treatment against arsenic-related both intestinal and neurological disorders.…”
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