A Review on Current Aspects of Curcumin-Based Effects in Relation to Neurodegenerative, Neuroinflammatory and Cerebrovascular Diseases by Claudia-Andreea Moldoveanu, Maria Tomoaia-Cotisel, Alexandra Sevastre-Berghian, Gheorghe Tomoaia, Aurora Mocanu, Csaba Pal-Racz, Vlad-Alexandru Toma, Ioana Roman, Madalina-Anca Ujica, Lucian-Cristian Pop

“…It also highlights the limitations posed by curcumin’s poor bioavailability and discusses ongoing efforts to surpass these impediments to harness the full therapeutic potential of curcumin in neurological disorders.…”
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Identification of Neurons Containing Calcium-Permeable AMPA and Kainate Receptors Using Ca2+ Imaging by Sergei Gaidin, Artem Kosenkov, Valery Zinchenko, Bakytzhan Kairat, Arailim Malibayeva, Sultan Tuleukhanov

“…This technique offers several advantages over existing methods, including the ability to assess large neuronal populations simultaneously, distinguish between different receptor types, and provide functional information about CP-AMPAR and CP-KAR expression in living neurons, making it a valuable tool for studying synaptic plasticity and neurological disorders.…”
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The Cardio- and Neuroprotective Effects of Corvitin and 2-Oxoglutarate in Rats with Pituitrin-Isoproterenol-Induced Myocardial Damage by V. Tkachenko, Y. Kovalchuk, N. Bondarenko, О. Bondarenko, G. Ushakova, A. Shevtsova

“…The imbalance between pro- and antioxidant systems, the formation of active carbonyl compounds, and the end products of glycation in the blood and tissues are the key moments in the development of heart and neurological disorders leading to a change of behavioral responses. …”
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Difficult to Treat Focal, Stiff Person Syndrome of the Left Upper Extremity by Nathan E. Esplin, John W. Stelzer, Timothy B. Legare, Sayed K. Ali

“…Stiff person syndrome (SPS) is a rare neurologic disorder characterized by muscle rigidity. It is a disorder of reduced GABA activity leading to increased muscle tone and often painful spasms. …”
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PET imaging of HIV-1 envelope protein gp120 using 18F-labeled nanobodies by Neysha Martinez-Orengo, Swati Shah, Jianhao Lai, Falguni Basuli, Anna Lyndaker, Mitchell L. Turner, Morteza Peiravi, Suman Sourabh, Kevon Sampson, Peng Zhang, Rolf E. Swenson, Paolo Lusso, Frank Maldarelli, Avindra Nath, Chuen-Yen Lau, Dima A. Hammoud

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Therapeutic potential of cannabinoids in neurological conditions: a systematic review of clinical trials by Alqassem Y. Hakami, Alqassem Y. Hakami, Fahad S. Alshehri

“…This review aims to assess the current clinical trials investigating cannabinoids, primarily Tetrahydrocannabinol and Cannabidiol, for neurological disorders. This review will aim to highlight the efficacy, safety, and outcome measures used in these trials.MethodsClinical trials were identified using ClinicalTrials.gov, focusing on studies that examined the effects of cannabinoids in treating neurological conditions. …”
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Functional Properties of Human Stem Cell-Derived Neurons in Health and Disease by Jason P. Weick

“…In order to more accurately assess potential therapies for neurological disorders, multiple strategies have been employed in recent years to produce neuronal populations that accurately represent in vivo regional and transmitter phenotypes. …”
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Can the internet based intervention ‘strategies for empowering activities in everyday life’ support people with cognitive difficulties to self-manage digital work and everyday life... by Monika Lindberg, Maria Ranner, Lars Jacobsson, Eva Månsson Lexell, Maria Larsson-Lund

“…To address this need, the internet-based intervention ‘Strategies for Empowering Activities in Everyday Life’ (SEE 2.0) was tested.Aim To explore and describe how SEE can support the development of self-management in people with cognitive difficulties who engage in digital work and other occupations in everyday life.Material and methods A qualitative, descriptive case study included four participants with cognitive difficulties due to neurological disorders who participated in SEE. Data were collected through semi-structured interviews, self-reports and assessments then analysed using pattern matching.Results Three cases were formed. …”
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Human platelet lysate: a potential therapeutic for intracerebral hemorrhage by Dachang Qiu, Lin Wang, Lanlan Wang, Yongfei Dong

“…We elucidate the role of platelets in ICH pathophysiology and highlight the limitations of the current treatment options and advancements in preclinical research on the application of HPL in neurological disorders. Furthermore, historical developments and preparation methods of HPL in the field of biomedicine are discussed. …”
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DNMT3a Downregulation Ttriggered Upregulation of GABAA Receptor in the mPFC Promotes Paclitaxel‐Induced Pain and Anxiety in Male Mice by Lixia Tian, Xu‐Hui Li, Yu‐Long Zhao, Hui‐Yuan Yi, Xue‐Ru Liu, Rongrong Yao, Xue‐Mei Hou, Xuan Zhu, Fu‐Quan Huo, Tao Chen, Lingli Liang

“…Notably, DNA methylation undergoes adaptive changes in neurological disorders, emerging as a promising target for neuromodulation. …”
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High-fat diet and neuroinflammation: The role of mitochondria by Mingxue Song, Yao Bai, Fuyong Song

“…As the key organelles responsible for energy metabolism in the cell, mitochondria are believed to involved in the pathogenesis of a variety of neurological disorders. This review summarizes the current progress in the field of the relationship between HFD exposure and neurodegenerative diseases, and outline the major routines of HFD induced neuroinflammation and its pathological significance in the pathogenesis of neurodegenerative diseases. …”
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Crosstalk between the Ketogenic Diet and Epilepsy: From the Perspective of Gut Microbiota by Yuying Fan, Hua Wang, Xueyan Liu, Junmei Zhang, Gang Liu

“…Given the association between a range of neurological disorders and changes in the gut microbiota, interest in the gut microbiota has recently increased. …”
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A ketogenic diet regulates microglial activation to treat drug addiction by Jie Ji, Yi Tang

“…In recent years, a ketogenic diet (KD) was shown to have therapeutic benefits as a dietary therapy for a variety of neurological disorders. With respect to drug addiction, studies have shown that a KD can alleviate glucose metabolism disorders caused by alcohol use disorders by increasing ketone metabolism, thereby reducing withdrawal symptoms. …”
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Development and Evaluation of a Rehabilitation Wheelchair with Multiposture Transformation and Smart Control by Wujing Cao, Hongliu Yu, Xinyu Wu, Sujiao Li, Qiaoling Meng, Chunjie Chen

“…Stroke and other neurological disorders have an effect on mobility which has a significant impact on independence and quality of life. …”
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Detection and location of EEG events using deep learning visual inspection. by Mohammad Amin Fraiwan

“…This signal contains a number of distinctive waveform patterns that reflect the subject's health state in relation to sleep, neurological disorders, memory functions, and more. In this regard, sleep spindles and K-complexes are two major waveform patterns of interest to specialists, who visually inspect the recordings to identify these events. …”
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Effects of Trace Metal Profiles Characteristic for Autism on Synapses in Cultured Neurons by Simone Hagmeyer, Katharina Mangus, Tobias M. Boeckers, Andreas M. Grabrucker

“…Various recent studies revealed that biometal dyshomeostasis plays a crucial role in the pathogenesis of neurological disorders such as autism spectrum disorders (ASD). …”
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Fluorescent Particles Based on Aggregation-Induced Emission for Optical Diagnostics of the Central Nervous System by Shan Liu, Jinkuan Liu, Xue Li, Xiaoxin Du, Cheng Yin, Yong Luo, Chenzhong Li

“…These advancements have enabled the visualization of various biomacromolecules and intracellular organelles, providing valuable insights into cellular microenvironments and statuses. Neurological disorders affect over 3 billion people worldwide, highlighting the urgent need for advanced diagnostic and therapeutic tools. …”
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Clinical Whole-Body Gait Characterization Using a Single RGB-D Sensor by Lukas Boborzi, Johannes Bertram, Roman Schniepp, Julian Decker, Max Wuehr

“…Instrumented gait analysis is widely used in clinical settings for the early detection of neurological disorders, monitoring disease progression, and evaluating fall risk. …”
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Traumatic Brain Injury Promotes Neurogenesis and Oligodendrogenesis in Subcortical Brain Regions of Mice by Olga Astakhova, Anna Ivanova, Ilia Komoltsev, Natalia Gulyaeva, Grigori Enikolopov, Alexander Lazutkin

“…Traumatic brain injury (TBI) is one of the major causes of severe neurological disorders and long-term dysfunction in the nervous system. …”
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Conformational diversity in class C GPCR positive allosteric modulation by Giuseppe Cannone, Ludovic Berto, Fanny Malhaire, Gavin Ferguson, Aurelien Fouillen, Stéphanie Balor, Joan Font-Ingles, Amadeu Llebaria, Cyril Goudet, Abhay Kotecha, Vinothkumar K.R., Guillaume Lebon

“…The mGlu receptors signal transduction can be allosterically potentiated by positive allosteric modulators (PAMs) binding to the 7TMs, which are of therapeutic interest in various neurological disorders. Here, we report the cryoEM structures of metabotropic glutamate receptor 5 (mGlu5) purified with three chemically and pharmacologically distinct PAMs. …”
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