Long non-coding RNA Malat1 modulates CXCR4 expression to regulate the interaction between induced neural stem cells and microglia following closed head injury by Qin Dong, Pengyu Chen, Wenqiao Qiu, Zhijun Yang, Yanteng Li, Yuhui Zhou, Lili Guo, Dan Zou, Ruxiang Xu, Mou Gao

“…Abstract Background Closed head injury (CHI) provokes a prominent neuroinflammation that may lead to long-term health consequences. …”
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Diet Control and Swimming Exercise Ameliorate HFD-Induced Cognitive Impairment Related to the SIRT1-NF-κB/PGC-1α Pathways in ApoE-/- Mice by Wei Wei, Zhicheng Lin, PeiTao Xu, Xinru Lv, Libin Lin, Yongxu Li, Yangjie Zhou, Taotao Lu, Xiehua Xue

“…High-fat diet- (HFD-) induced neuroinflammation may ultimately lead to an increased risk of cognitive impairment. …”
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A Review: Inflammatory Process in Alzheimer's Disease, Role of Cytokines by Jose Miguel Rubio-Perez, Juana Maria Morillas-Ruiz

“…Other important cytokines in neuroinflammation are IL-6 and tumor necrosis factor (TNF)-α. …”
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Chronic active lesions in multiple sclerosis: classification, terminology, and clinical significance by Assunta Dal-Bianco, Jiwon Oh, Pascal Sati, Martina Absinta

“…This condition, known as smoldering neuroinflammation, is present across the clinical spectrum of MS and is currently understood to be relatively resistant to treatment with existing disease-modifying therapies. …”
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Phytocannabinoids: a new frontier in Alzheimer’s disease management by Jagadeesh S. Rao

“…The pathogenic characteristics encompass the existence of amyloid plaques outside the cells, neurofibrillary tangles inside the cells, neuroinflammation, oxidative stress, and the loss of synapses. …”
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Activity-based chemical proteomics reveals caffeic acid ameliorates pentylenetetrazol-induced seizures by covalently targeting aconitate decarboxylase 1 by Guanjun Li, Ling Huang, Di Gu, Peili Wang, Letai Yi, Wenhua Kuang, Ying Zhang, Junzhe Zhang, Dandan Liu, Qiaoli Shi, Huan Tang, Jichao Sun, Guohua Zeng, Xin Peng, Jigang Wang

“…Abstract Background Epilepsy is a neurological disorder characterized by recurrent seizures, tightly associated with neuroinflammation. Activation of inflammatory cells and molecules in damaged nervous tissues plays a pivotal role in epilepsy. …”
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Alzheimer’s Disease and <i>Porphyromonas gingivalis</i>: Exploring the Links by Ivana Shawkatova, Vladimira Durmanova, Juraj Javor

“…This review examines evidence connecting <i>P. gingivalis</i> to hallmark AD features, such as amyloid β accumulation, tau hyperphosphorylation, neuroinflammation, and other neuropathological features consistent with AD. …”
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Neuroprotection by chronic administration of Fluoroethylnormemantine (FENM) in mouse models of Alzheimer's disease by Allison Carles, Aline Freyssin, Sarra Guehairia, Thomas Reguero, Michel Vignes, Hélène Hirbec, Gilles Rubinstenn, Tangui Maurice

“…In APP/PS1 mice, FENM infused or administered IP alleviated spontaneous alternation deficits, neuroinflammation, increases in Aβ1-40/Aβ1-42 and hippocampal LTP alteration. …”
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Blockade of IL-17A/IL-17R Pathway Protected Mice from Sepsis-Associated Encephalopathy by Inhibition of Microglia Activation by Bo Ye, Tianzhu Tao, Andong Zhao, Liyuan Wen, Xiaofei He, Yi Liu, Qiang Fu, Weidong Mi, Jingsheng Lou

“…Treatment with recombinant IL-17A enhanced the neuroinflammation and microglia activation in CLP mice. …”
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Uvaol attenuates TGF-β1-induced epithelial-mesenchymal transition in human alveolar epithelial cells by modulating expression and membrane localization of β-catenin by Liliane Patrícia Gonçalves Tenório, Liliane Patrícia Gonçalves Tenório, Liliane Patrícia Gonçalves Tenório, Liliane Patrícia Gonçalves Tenório, Liliane Patrícia Gonçalves Tenório, Felipe Henrique da Cunha Xavier, Felipe Henrique da Cunha Xavier, Felipe Henrique da Cunha Xavier, Felipe Henrique da Cunha Xavier, Mônica Silveira Wagner, Kayo Moreira Bagri, Erick Gabriel Alves Ferreira, Romulo Galvani, Romulo Galvani, Romulo Galvani, Romulo Galvani, Claudia Mermelstein, Adriana Cesar Bonomo, Adriana Cesar Bonomo, Adriana Cesar Bonomo, Adriana Cesar Bonomo, Wilson Savino, Wilson Savino, Wilson Savino, Wilson Savino, Emiliano Barreto, Emiliano Barreto

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Nonpharmacological Modulation of Chronic Inflammation in Parkinson’s Disease: Role of Diet Interventions by Stefania Kalampokini, Anouck Becker, Klaus Fassbender, Epameinondas Lyros, Marcus M. Unger

“…Neuroinflammation is increasingly recognized as an important pathophysiological feature of neurodegenerative diseases such as Parkinson’s disease (PD). …”
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Protective effect of silencing lncRNA HCP5 against brain injury after intracerebral hemorrhage by targeting miR-195-5p by Zhanhua Lu, Kun Huang

“…Conclusions Silencing HCP5 can alleviate brain edema, neurological dysfunction, neuroinflammation, and oxidative stress caused by ICH via miR-195-5p.…”
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Role of PPARs in Progression of Anxiety: Literature Analysis and Signaling Pathways Reconstruction by Olga I. Rudko, Artemii V. Tretiakov, Elena A. Naumova, Eugene A. Klimov

“…Possible mechanism of PPAR involvement in neuroinflammation protection is proposed. Signal pathway reconstruction and reviewing aimed to reveal possible connection between PPARG and CCK-ergic system was conducted. …”
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Prior Exposure to Immunosuppressors Sensitizes Retinal Microglia and Accelerates Optic Nerve Regeneration in Zebrafish by Ilse Bollaerts, Jessie Van houcke, An Beckers, Kim Lemmens, Sophie Vanhunsel, Lies De Groef, Lieve Moons

“…Recent work has shown that appropriate modulation of acute neuroinflammation upon CNS injury can trigger a regenerative response; yet, the underlying cellular and molecular mechanisms remain largely elusive. …”
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S-Equol, a Major Isoflavone from Soybean, Inhibits Nitric Oxide Production in Lipopolysaccharide-Stimulated Rat Astrocytes Partially via the GPR30-Mediated Pathway by Mitsuaki Moriyama, Ayano Hashimoto, Hideyo Satoh, Kenji Kawabe, Mizue Ogawa, Katsura Takano, Yoichi Nakamura

“…Cumulative evidence indicates that estrogen receptor (ER) agonists attenuate neuroinflammation. Equol, a major isoflavone from soybean, exhibits estrogen-like biological activity, but their effect on inflammatory response has not been well established. …”
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Performance of the 2023 diagnostic criteria for MOGAD: real-world application in a Chinese multicenter cohort of pediatric and adult patients by Meng-Ting Cai, Yi Hua, Qi-Lun Lai, Sheng-Yao Su, Chun-Hong Shen, Song Qiao, Yong-Feng Xu, Zhe-Feng Yuan, Yin-Xi Zhang

“…The 2023 Lancet Neurology criteria were assessed against the benchmark of empirical clinical diagnosis, and the 2018 JAMA Neurology and Journal of Neuroinflammation criteria were also evaluated for comparative analysis. …”
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Long-term effects of linear versus macrocyclic GBCAs on gene expression in the central nervous system of mice by Chuanbing Wang, Yuxia Tang, Jiajia Tang, Jie Zhang, Siqi Wang, Feiyun Wu, Shouju Wang

“…Reactome pathway analysis showed enrichment in neuroinflammation pathways. No DEGs were detected in brains on day 29. …”
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Enhanced glycolysis-derived lactate promotes microglial activation in Parkinson’s disease via histone lactylation by Qixiong Qin, Danlei Wang, Yi Qu, Jiangting Li, Ke An, Zhijuan Mao, Jingyi Li, Yongjie Xiong, Zhe Min, Zheng Xue

“…Importantly, inhibiting SLC7A11 by sulfasalazine mitigated microglia-mediated neuroinflammation and improved motor function in PD mice. …”
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Pediatric autoimmune neuropsychiatric disorders associated with streptococcal infections and gut microbiota composition: what do we know? by Veronica Maria Tagi, Veronica Maria Tagi, Martina Tosi, Martina Tosi, Ilenia Pia Greco, Eliana Stucchi, Elvira Verduci, Elvira Verduci, Gianvincenzo Zuccotti, Gianvincenzo Zuccotti

“…Notable changes include reduced microbial diversity and shifts in bacterial populations, which affect metabolic functions crucial for neuroinflammation. Elevated serum levels of sNOX2-dp and isoprostanes indicate oxidative stress, while the presence of lipopolysaccharides (LPS) may contribute to neuroinflammation. …”
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The Regulation Effect of α7nAChRs and M1AChRs on Inflammation and Immunity in Sepsis by Song Hu, Yundong Wang, Hongbing Li

“…Correcting the neuroinflammation of these regulatory centers and adjusting the function of α7nAChRs and M1AChRs may be two key strategies for the treatment of sepsis in the future.…”
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