Human lineage mutations regulate RNA-protein binding of conserved genes NTRK2 and ITPR1 involved in human evolution by Min Zhao, Weichen Song, Shunying Yu, Wenxiang Cai, Guan Ning Lin

“…These genes also carried excess damaging coding mutations that caused neurodevelopmental disorders, ataxia and schizophrenia. Among these genes, NTRK2 and ITPR1 had the most aggregated evidence of functional importance, suggesting their essential roles in cognition and bipedalism.Conclusions Our findings suggest that a small subset of human-specific mutations have contributed to human speciation through impacts on post-transcriptional modification of critical brain-related genes.…”
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Immune Dysfunction in Tourette Syndrome by Ishraga Elamin, Mark J. Edwards, Davide Martino

“…The association between immunity and neurodevelopmental disorders has been extensively investigated in autism, suggesting a potential involvement of both cellular and humoral immunity in the establishment of synaptic connectivity modulation during development. …”
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Narrative microstructure and macrostructure in adolescents with Down syndrome and Williams syndrome by Aitana Viejo, Maite Fernández-Urquiza, Eliseo Diez-Itza

“…Down syndrome (DS) and Williams syndrome (WS) are genetic neurodevelopmental disorders associated with intellectual disability, showing contrasting linguistic profiles with asymmetries in grammatical (DS weakness/WS strength) vs. pragmatic abilities (DS strength/WS weakness). …”
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Deafferentation-Induced Plasticity of Visual Callosal Connections: Predicting Critical Periods and Analyzing Cortical Abnormalities Using Diffusion Tensor Imaging by Jaime F. Olavarria, Andrew S. Bock, Lindsey A. Leigland, Christopher D. Kroenke

“…Last, we discuss the potential of utilizing DTI to distinguish normal from abnormal cerebral cortical development, both within the context of aberrant connectivity induced by early retinal deafferentation, and more generally as a potential tool for detecting abnormalities associated with neurodevelopmental disorders.…”
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Prevalence and comorbidity rates of disruptive mood dysregulation disorder in epidemiological and clinical samples: systematic review and meta-analysis by Xavier Benarous, Hélène Lahaye, Angèle Consoli, David Cohen, Réal Labelle, Jean-Marc Guilé

“…The association with other neurodevelopmental disorders remained poorly investigated. …”
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In search of prosociality in rodents: A scoping review. by Valérie Charron, Joey Talbot, Patrick R Labelle, Anne T M Konkle, Hélène Plamondon

“…Studying prosociality in rodents can provide insight into brain mechanisms potentially related to neurodevelopmental disorders known to impact social behaviors (e.g., autism spectrum disorder). …”
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PWS/AS MS-MLPA Confirms Maternal Origin of 15q11.2 Microduplication by Angelika J. Dawson, Janice Cox, Karine Hovanes, Elizabeth Spriggs

“…The proximal region of the long arm of chromosome 15q11.2-q13 is associated with various neurodevelopmental disorders, including Prader-Willi (PWS) and Angelman (AS) syndromes, autism, and other developmental abnormalities resulting from deletions and duplications. …”
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Erythrocyte Shape Abnormalities, Membrane Oxidative Damage, and β-Actin Alterations: An Unrecognized Triad in Classical Autism by Lucia Ciccoli, Claudio De Felice, Eugenio Paccagnini, Silvia Leoncini, Alessandra Pecorelli, Cinzia Signorini, Giuseppe Belmonte, Roberto Guerranti, Alessio Cortelazzo, Mariangela Gentile, Gloria Zollo, Thierry Durand, Giuseppe Valacchi, Marcello Rossi, Joussef Hayek

“…Here, we investigated RBC morphology by scanning electron microscopy in patients with classical autism, that is, the predominant ASDs phenotype (age range: 6–26 years), nonautistic neurodevelopmental disorders (i.e., “positive controls”), and healthy controls (i.e., “negative controls”). …”
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Profiles of Early Expressive Phonological Skills-Brazilian Portuguese (PEEPS-BP): a diagnostic accuracy study by Simone Nicolini de Simoni, Denis Altieri de Oliveira Moraes, Karina Carlesso Pagliarin, Márcia Keske-Soares

“…The sample consisted of 30 children with no identified neurodevelopmental disorders aged 24 to 36 months. Twenty-three were part of the control group, and seven were part of the clinical group, which consisted of children with reported delays in vocabulary acquisition and phonological development. …”
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Coexisting Congenital Mesoblastic Nephroma and Lissencephaly: Unique Case Report with Pathological Analysis and Its Clinical Significance by Hristina Zakić, Olivera Kontić Vučinić, Jelena Stamenković, Jovan Jevtić, Milena Perišić Mitrović, Maja Životić

“…Lissencephaly belongs to a rare category of neurodevelopmental disorders marked by the absence of a substantial reduction in the typical folds and grooves in the cerebral cortex. …”
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Cerebral organoids: a promising model in cellular technologies by T. A. Shnaider

“…In addition, we discuss successful implementation of this technology in fundamental and applied research like modeling of different neurodevelopmental disorders and drug screening. Finally, we regard existing problems and prospects for development of human pluripotent stem cell-derived threedimensional cerebral organoid technology.…”
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Contribution of a virtual magic camp to enhancing self-esteem in children with ADHD: A pilot study by Hon K. Yuen, Kevin Spencer, Kimberly Kirklin, Lauren Edwards, Gavin R. Jenkins

“…Magic, a performing art, when used therapeutically, has been shown to enhance self-esteem in children with neurodevelopmental disorders. However, there is a paucity of evaluation studies using this intervention applied to children with ADHD…”
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A systematic review of exposure to toxic elements and neurocognitive development in children by Tingyi Guo, Moslem Lari Najafi, Junmei Zhang

“…Exposure to potentially toxic elements (PTEs) has been implicated in neurodevelopmental disorders and cognitive deficits in children. …”
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Neurodevelopment in very low birth weight newborns in Matanzas during 2016-2018 by Gerardo Rogelio Robaina Castellanos, Solangel de la Caridad Riesgo Rodríguez, Dariana Hernández Morales

“…<br /><strong>Conclusion</strong>: The incidence of neurodevelopmental disorders at two years old of corrected age in very low birth weight newborns in Matanzas was lower in the period studied, in relation to previous years, although this finding was not statistically significant.…”
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Can attention-deficit/hyperactivity disorder be considered a form of cerebellar dysfunction? by Valeria Isaac, Vladimir Lopez, Maria Josefina Escobar

“…The rapidly growing field of the clinical cognitive neuroscience of the cerebellum has begun to relate cerebro-cerebellar circuits to neurodevelopmental disorders. While the cerebellum’s role in motor function, such as balance, motor coordination, and execution, is well recognized, ongoing research has evidenced its additional and fundamental role in neurocognitive development and executive function, including attention and social cognition, which are all areas of impairment commonly found in ADHD. …”
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Dissociable genetic influences on eye movements during abstract versus naturalistic social scene viewing in infancy by Ana Maria Portugal, Mark J. Taylor, Kristiina Tammimies, Angelica Ronald, Terje Falck-Ytter

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Multi-modal investigation reveals pathogenic features of diverse DDX3X missense mutations. by Federica Mosti, Mariah L Hoye, Carla F Escobar-Tomlienovich, Debra L Silver

“…De novo mutations in the RNA binding protein DDX3X cause neurodevelopmental disorders including DDX3X syndrome and autism spectrum disorder. …”
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The Royal College of Psychiatrists Child and Adolescent Psychiatry Surveillance System for rare events and disorders: highlighting the need for an international network for surveil... by Muthukrishnan Venkatesan, Eleanor Smith, Marinos Kyriakopoulos, Aditya Narain Sharma

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Prevalence of specific learning disability in children and its association with somatic symptom disorder – data from a tertiary care centre of South India by Nishanth Rajan, Priya Jose, Peter Prasanth Kumar Kommu, Shanthi Kannan

“…Background: Specific learning disability is one of the neurodevelopmental disorders with problems in one of the basic skills such as reading, writing, and arithmetic. …”
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Neuron-Specific Fluorescence Reporter-Based Live Cell Tracing for Transdifferentiation of Mesenchymal Stem Cells into Neurons by Chemical Compound by Do Won Hwang, Hyun Woo Kwon, Jaeho Jang, Hee Jung Jung, Kwang Rok Kim, Dong Soo Lee

“…Although transdifferentiation of mesenchymal stem cells (MSCs) into neurons increases the possibility of therapeutic use of MSCs for neurodevelopmental disorders, the use of MSCs has the limitation on differentiation efficiency to neuronal lineage and lack of an easy method to monitor the transdifferentiation. …”
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