Late Onset Atypical Pantothenate-Kinase-Associated Neurodegeneration by Natalie Diaz

“…Pantothenate-kinase-associated neurodegeneration (PKAN) is a rare genetic disease and a form of neurodegeneration with brain iron accumulation (NBIA). …”
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Cytokines and Chemokines at the Crossroads of Neuroinflammation, Neurodegeneration, and Neuropathic Pain by Geeta Ramesh, Andrew G. MacLean, Mario T. Philipp

“…The dysregulation of cytokines and chemokines is a central feature in the development of neuroinflammation, neurodegeneration, and demyelination both in the central and peripheral nervous systems and in conditions of neuropathic pain. …”
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GSK-3β at the Intersection of Neuronal Plasticity and Neurodegeneration by Tomasz Jaworski, Ewa Banach-Kasper, Katarzyna Gralec

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Protective effects of apigenin in neurodegeneration: An update on the potential mechanisms by Ali Mohammadkhanizadeh, Mohammad Sheibani, Soroush Taherkhani, Davood Nourabadi, Seyed Mahdi Mohamadi-Zarch, Farnaz Nikbakht, Yaser Azizi

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Biofilm-associated proteins: from the gut biofilms to neurodegeneration by Jaione Valle

“…The overlooked interplay between bacterial amyloids and the host may have detrimental consequences for the host, including neurodegeneration. This work gives an overview of the biofilm-associated amyloids expressed by the gut microbiota and their potential role in neurodegeneration. …”
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NLRX1 limits inflammatory neurodegeneration in the anterior visual pathway by Alexander J. Gill, Matthew D. Smith, Danny Galleguillos, Thomas Garton, Jackson W. Mace, Sachin P. Gadani, Swati Kumar, Aayush Pokharel, Krista Solem, Saahith Potluri, Omar Hussein, Giuliana Sardi Rogines, Arihant Singh, Annatje Clark, Peter A. Calabresi, Marjan Gharagozloo

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Editorial: Neurodegeneration and cognitive impairment after traumatic brain injury by Tao Liu, Tao Liu, Tao Liu, Li Ma, Yu Chen, Rongcai Jiang, Rongcai Jiang

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VDAC1: A Key Player in the Mitochondrial Landscape of Neurodegeneration by Shirel Argueti-Ostrovsky, Shir Barel, Joy Kahn, Adrian Israelson

“…This review summarizes the current findings on the contribution of VDAC1 to neurodegeneration, focusing on its interactions with disease-specific proteins, such as amyloid-β, α-synuclein, and mutant SOD1. …”
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Editorial: Lipid metabolism dysregulation in obesity-related diseases and neurodegeneration by Jialiu Zeng, Jialiu Zeng, Chih Hung Lo, Chih Hung Lo

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Role of Copper and Zinc Ions in the Hydrolytic Degradation of Neurodegeneration-Related Peptides by Valentina Pirota, Enrico Monzani, Simone Dell’Acqua, Chiara Bacchella

“…Spontaneous cleavage reactions normally occur in vivo on amino acid peptide backbones, leading to fragmentation products that can have different physiological roles and toxicity, particularly when the substrate of the hydrolytic processes are neuronal peptides and proteins highly related to neurodegeneration. We report a hydrolytic study performed with the HPLC-MS technique at different temperatures (4 °C and 37 °C) on peptide fragments of different neuronal proteins (amyloid-β, tau, and α-synuclein) in physiological conditions in the presence of Cu²⁺ and Zn²⁺ ions, two metal ions found at millimolar concentrations in amyloid plaques. …”
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Neurodegeneration in Patients with Type 2 Diabetes Mellitus without Diabetic Retinopathy by Elena Garcia-Martin, Marta Cipres, Isabel Melchor, Laura Gil-Arribas, Elisa Vilades, Vicente Polo, Maria Jesus Rodrigo, Maria Satue

“…Purpose. To evaluate neurodegeneration in patients with type 2 diabetes mellitus (DM2) without diabetic retinopathy and to assess the possible role of systemic vascular complications in retinal changes. …”
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Sex-specific ultrasound imaging biomarkers of neurodegeneration in a mouse model by Mark B. Russell, Drew P. Locke, Haley M. Adams, Alexander R. Pelley, Rojan Saghian, Rojan Saghian, Alexandre S. Maekawa, Darcie Stapleton, Grace V. Mercer, John G. Sled, John G. Sled, John G. Sled, Lindsay S. Cahill, Lindsay S. Cahill

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Phosphodiesterase-5 Inhibitors: Action on the Signaling Pathways of Neuroinflammation, Neurodegeneration, and Cognition by Christina Alves Peixoto, Ana Karolina Santana Nunes, Ana Garcia-Osta

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Acid-Sensing Ion Channels as Potential Therapeutic Targets in Neurodegeneration and Neuroinflammation by Audrey Ortega-Ramírez, Rosario Vega, Enrique Soto

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Magnetic susceptibility components reveal different aspects of neurodegeneration in alpha-synucleinopathies by Oliver C. Kiersnowski, Pietro Mattioli, Lucia Argenti, Laura Avanzino, Francesco Calizzano, Andrea Diociasi, Laura Falcitano, Chunlei Liu, Mattia Losa, Federico Massa, Silvia Morbelli, Beatrice Orso, Elisa Pelosin, Stefano Raffa, Matteo Pardini, Dario Arnaldi, Luca Roccatagliata, Mauro Costagli

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Sirtuin-2 Protects Neural Cells from Oxidative Stress and Is Elevated in Neurodegeneration by Preeti Singh, Peter S. Hanson, Christopher M. Morris

“…The mammalian SIRT2 has been implicated in Parkinson’s disease (PD) where studies suggest SIRT2 promotes neurodegeneration. We therefore evaluated the effects of SIRT2 manipulation in toxin treated SH-SY5Y cells and determined the expression and activity of SIRT2 in postmortem brain tissue from patients with PD. …”
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Stat3 mediates Fyn kinase-driven dopaminergic neurodegeneration and microglia activation by Sahiba Siddiqui, Fang Liu, Anumantha G. Kanthasamy, Maura McGrail

Subjects: “…zebrafish neurodegeneration model…”
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Synaptic Paths to Neurodegeneration: The Emerging Role of TDP-43 and FUS in Synaptic Functions by Shuo-Chien Ling

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Relationship between Zinc (Zn2+) and Glutamate Receptors in the Processes Underlying Neurodegeneration by Bartłomiej Pochwat, Gabriel Nowak, Bernadeta Szewczyk

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Dysregulation of Metabolic Peptides in the Gut–Brain Axis Promotes Hyperinsulinemia, Obesity, and Neurodegeneration by Camille Green, Vandana Zaman, Kayce Blumenstock, Narendra L. Banik, Azizul Haque

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