Prevalence of asymptomatic Leishmania donovani infection and associated factors in Ethiopia: a systematic review and meta-analysis by Habtamu Belay, Adugna Abera, Esayas Aklilu, Tesfahun Bishaw, Ayinalem Alemu, Geremew Tasew, Berhanu Erko

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Genome-wide association study analysis of single nucleotide variants in L. infantum associated with IL-6 inflammatory response in visceral leishmaniasis by Amanda Miranda da Silva, Kátia Silene Sousa Carvalho, Caio Andrey Bezerra Januário, Raquel Gomes de Sena Carneiro Caldas, Bianka Lopes da Silva Paulino, Débora Cavalcante Braz, Dorcas Lamounier Costa, Gabriel da Luz Wallau, Wilson Jose da Silva Junior, Carlos Henrique Nery Costa

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Jejunal Ulcer Caused by Schistosoma japonicum by Daniela Jaqueline Rivadeneira, Hesheng Luo

“…Schistosomiasis is one of the neglected tropical diseases that affect the poorest. Although a great improvement has been made to control it, there is a lot of work that remains to be fulfilled.…”
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Comparative performance of microscopy, rapid diagnostic tests, and multiplex real-time PCR for detection of malaria parasites among pregnant women in northwest Ethiopia by Zemenu Tamir, Abebe Animut, Sisay Dugassa, Araya Gebresilassie, Mahlet Belachew, Adugna Abera, Berhanu Erko

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Developments in Diagnosis and Antileishmanial Drugs by Prachi Bhargava, Rajni Singh

“…Leishmaniasis ranks the third in disease burden in disability-adjusted life years caused by neglected tropical diseases and is the second cause of parasite-related deaths after malaria; but for a variety of reasons, it is not receiving the attention that would be justified seeing its importance. …”
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Prevalence of Lymphatic Filariasis based on Morbidity and Healthcare-seeking Practices of Patients in a Gram Panchayat of Paschim Burdwan District, West Bengal by Indranil Saha, Russoti Das, Ajay K. Mandal, Pinki Darlami, Subhajit Datta, Gautam Ghose, Sanjit Dey

“…Lymphatic filariasis is one of the neglected tropical diseases still present in many areas. A community-based cross-sectional study was conducted during 2019–2020 in the Gourbazar gram panchayat area of Paschim Burdwan District, West Bengal, to find out the prevalence of lymphatic filariasis based on morbidity and its distribution in terms of selected sociodemographic variables and to assess the healthcare-seeking practices of the affected people. …”
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Plants Used in Antivenom Therapy in Rural Kenya: Ethnobotany and Future Perspectives by Timothy Omara

“…Snake envenomation is one of the neglected tropical diseases which has left an intolerable death toll and severe socioeconomic losses in Kenya. …”
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Metagenomic next-generation sequencing assists in the diagnosis of visceral leishmaniasis in non-endemic areas of China by Rui Zhao, Guilun He, Lin Xiang, Melinda Ji, Rongheng He, Xudong Wei

“…With 12 million cases globally, leishmaniasis is one of the most serious neglected tropical diseases worldwide. Direct identification of infected tissues is currently the primary method of diagnosis; however, the low sensitivity and inconvenience of microscopic examination in detecting amastigotes, parasitic manifestations of Leishmania, leads to the possibility of misdiagnosis, delayed diagnosis, and underdiagnosis.MethodsWith the development of metagenomic nextgeneration sequencing (mNGS) technology for pathogen identification, it is possible to detect specific nucleic acid sequences characteristic of Leishmania parasites, which opens new avenues for the more accurate diagnosis of leishmaniasis. …”
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4-Aminoquinoline as a privileged scaffold for the design of leishmanicidal agents: structure–property relationships and key biological targets by Angel H. Romero, Francisco Delgado

“…Leishmaniasis is one of the most important neglected tropical diseases, with more than two million new cases annually. …”
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Prevalence, Intensity, and Associated Factors of Schistosoma mansoni among School Children in Northwest Ethiopia by Ayalew Jejaw Zeleke, Ayenew Addisu, Yalewayker Tegegne

“…Schistosomiasis is one of the Neglected Tropical Diseases in Ethiopia, and its burden may show variations from time to time across different regions. …”
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Towards global elimination of lymphatic filariasis: a systematic review of the application of spatial epidemiological methods to enhance surveillance and support elimination progra... by Angela Cadavid Restrepo, Colleen L Lau, Beatris Mario Martin, Helen J Mayfield

“…Background In recent decades, spatial epidemiology has increasingly been used to study neglected tropical diseases (NTDs). Spatial methods are particularly relevant when transmission is strongly driven by sociodemographic and environmental factors, resulting in heterogeneous disease distribution. …”
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Prevalence of S. mansoni Infection and Associated Risk Factors among School Children in Guangua District, Northwest Ethiopia by Belaynesh Tazebew, Denekew Temesgen, Mastewal Alehegn, Desalew Salew, Molalign Tarekegn

“…Schistosomiasis is one of the neglected tropical diseases and is prevalent in tropics. It causes morbidity and mortality in developing countries including Ethiopia. …”
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Efficacy of single dose praziquantel against Schistosoma mansoni in East Africa: a systematic review and meta-analysis by Miseganaw Sisay, Tadesse Hailu, Destaw Damtie, Kindu Geta, Lamesgen Zelalem, Degisew Misganaw

“…Abstract The genus Schistosoma causes a schistosomiasis which is one of the neglected tropical diseases that pose a major threat to public health in East Africa. …”
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Pretreatment with serine protease inhibitors impairs Leishmania amazonensis survival on macrophages by Patrícia de Almeida Machado, Pollyanna Stephanie Gomes, Elaine Soares Coimbra, Herbert Leonel de Matos Guedes

“…Abstract Background Leishmaniases are neglected tropical diseases with great clinical and epidemiological importance. …”
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Spacetime modeling of mortality by infectious and parasitic diseases in Brazil: a 20-year ecological and population-based study by Lucas Almeida Andrade, Carlos Dornels Freire de Souza, Wandklebson Silva da Paz, Danilo de Gois Souza, José Augusto Passos Góes, Emerson Lucas Silva Camargo, Álvaro Francisco Lopes de Sousa, Liliane Moretti Carneiro, Isabel Amélia Costa Mendes, Karina Machado Araújo, Allan Dantas dos Santos, Márcio Bezerra-Santos

“…The leading causes of death included acute respiratory infections ( n  = 1,130,069; 52.49%), septicemia ( n  = 289,817; 13.46%), human immunodeficiency virus/acquired immunodeficiency syndrome ( n  = 232,892; 10.82%), tuberculosis ( n  = 104,121; 4.84%), and neglected tropical diseases such as Chagas disease ( n  = 94,788; 4.40%) and schistosomiasis ( n  = 10,272; 0.48%). …”
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Post-COVID-19 resurgence of scabies’ cases in the Lazio Region, Italy: a new emerging public health threat? by Martina Spaziante, Alessandro Agresta, Maurizio D’Amato, Gabriella De Carli, Gilda Tonziello, Valentina Vantaggio, Giorgio Nicolò Malatesta, Enrico Girardi, Alessandra Barca, Paola Scognamiglio, Francesco Vairo

“…Abstract Scabies represents a global health issue and in 2017 was added to the World Health Organization’s list of neglected tropical diseases. In European and Middle Eastern countries, cases are sporadic while recent surveillance data have pointed out an increasing incidence among vulnerable populations. …”
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High Seropositivity of Brucella melitensis Antibodies among Pregnant Women Attending Health Care Facilities in Mwanza, Tanzania: A Cross-Sectional Study by Helmut A. Nyawale, Michael Simchimba, Joseph Mlekwa, Fridolin Mujuni, Elieza Chibwe, Prosper Shayo, Elifuraha B. Mngumi, Khadija S. Majid, Mtebe Majigo, Stephen E. Mshana, Mariam M. Mirambo

“…Brucellosis is one of the most prevalent zoonotic neglected tropical diseases across the globe. Brucella melitensis (B. melitensis), the most pathogenic species is responsible for several pregnancy adverse outcomes in both humans and animals. …”
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Prevalence of Intestinal Schistosomiasis and Associated Factors among School Children in Wondo District, Ethiopia by Mustafa Geleto Ansha, Kemal Ahmed Kuti, Ephrem Girma

“…Human schistosomiasis is one of the neglected tropical diseases caused by Schistosoma mansoni. Children in the developing countries live in areas with poor sanitation and most often spend time swimming or bathing in the water bodies contaminated with cercariae, the infective stages of schistosomiasis, which results in growth retardation and poor school performance. …”
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In silico design of an epitope-based vaccine ensemble for fasliolopsiasis by Ruchishree Konhar, Ruchishree Konhar, Kanhu Charan Das, Kanhu Charan Das, Aiboklang Nongrum, Rohan Raj Samal, Shailesh Kumar Sarangi, Devendra Kumar Biswal, Devendra Kumar Biswal

“…Finding successful vaccination antigen combinations from these huge number of genes/proteins in the available omics datasets is the key in combating these neglected tropical diseases. In the present study, we developed an in silico workflow to select antigens for composing a chimeric vaccine, which could be a significant technique for developing a fasciolopsiasis vaccine that prevents the parasite from causing serious harm.Results and discussionThis chimeric vaccine can now be tested experimentally and compared to other vaccine candidates to determine its potential influence on human health. …”
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Development of a Loop Mediated Isothermal Amplification for Diagnosis of Ascaris lumbricoides in Fecal Samples by Esther A. Shiraho, Agola L. Eric, Ibrahim N. Mwangi, Geoffrey M. Maina, Joseph M. Kinuthia, Martin W. Mutuku, Robert M. Mugambi, Jackson M. Mwandi, Gerald M. Mkoji

“…It is also considered among the neglected tropical diseases. Diagnosis relies mainly on microscopy-based methods which are laborious, are limited by low sensitivity, and require high expertise. …”
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