Artificial intelligence-driven rational design of ionizable lipids for mRNA delivery by Wei Wang, Kepan Chen, Ting Jiang, Yiyang Wu, Zheng Wu, Hang Ying, Hang Yu, Jing Lu, Jinzhong Lin, Defang Ouyang

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Orbital-order as the driving mechanism for superconductivity in ruthenates by Álvaro Adrián Carrasco Álvarez, Sébastien Petit, Wilfrid Prellier, Manuel Bibes, Julien Varignon

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Real-world clinical multi-omics analyses reveal bifurcation of ER-independent and ER-dependent drug resistance to CDK4/6 inhibitors by Zhengyan Kan, Ji Wen, Vinicius Bonato, Jennifer Webster, Wenjing Yang, Vladimir Ivanov, Kimberly Hyunjung Kim, Whijae Roh, Chaoting Liu, Xinmeng Jasmine Mu, Jennifer Lapira-Miller, Jon Oyer, Todd VanArsdale, Paul A. Rejto, Jadwiga Bienkowska

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Single cell suppression profiling of human regulatory T cells by Jonas Nørskov Søndergaard, Janyerkye Tulyeu, David Priest, Shimon Sakaguchi, James B. Wing

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Time-domain signatures of distinct correlated insulators in a moiré superlattice by Eric A. Arsenault, Yiliu Li, Birui Yang, Takashi Taniguchi, Kenji Watanabe, James C. Hone, Cory R. Dean, Xiaodong Xu, X.-Y. Zhu

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Aggregation control of anionic pentamethine cyanine enabling excitation wavelength selective NIR-II fluorescence imaging-guided photodynamic therapy by Yibin Li, Fei Qu, Fang Wan, Cheng Zhong, Jingyi Rao, Yijing Liu, Zhen Li, Jintao Zhu, Zhong’an Li

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Ab initio machine-learning unveils strong anharmonicity in non-Arrhenius self-diffusion of tungsten by Xi Zhang, Sergiy V. Divinski, Blazej Grabowski

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MAT2A inhibitor AG-270/S095033 in patients with advanced malignancies: a phase I trial by Mrinal Gounder, Melissa Johnson, Rebecca S. Heist, Geoffrey I. Shapiro, Sophie Postel-Vinay, Frederick H. Wilson, Elena Garralda, Gerburg Wulf, Caroline Almon, Salah Nabhan, Elia Aguado-Fraile, Peng He, Mathilde Romagnoli, Mohammad Hossain, Rohini Narayanaswamy, Amel Sadou-Dubourgnoux, Michael Cooper, Vasileios Askoxylakis, Howard A. Burris, Josep Tabernero

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Earthworm inspired lubricant self-pumping hydrogel with sustained lubricity at high loading by Shuanhong Ma, Lunkun Liu, Weiyi Zhao, Renjie Li, Xiaoduo Zhao, Yunlei Zhang, Bo Yu, Ying Liu, Feng Zhou

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Marine species and assemblage change foreshadowed by their thermal bias over Early Jurassic warming by Carl J. Reddin, Jan P. Landwehrs, Gregor H. Mathes, Clemens V. Ullmann, Georg Feulner, Martin Aberhan

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The structural basis of protective and nonprotective human monoclonal antibodies targeting the parainfluenza virus type 3 hemagglutinin-neuraminidase by Rose J. Miller, Ian A. Durie, Aaron D. Gingerich, Mohamed A. Elbehairy, Abigail G. Branch, Riley G. Davis, Nada Abbadi, Melinda A. Brindley, Jarrod J. Mousa

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Invasion of glioma cells through confined space requires membrane tension regulation and mechano-electrical coupling via Plexin-B2 by Chrystian Junqueira Alves, Theodore Hannah, Sita Sadia, Christy Kolsteeg, Angela Dixon, Robert J. Wiener, Ha Nguyen, Murray J. Tipping, Júlia Silva Ladeira, Paula Fernandes da Costa Franklin, Nathália de Paula Dutra de Nigro, Rodrigo Alves Dias, Priscila V. Zabala Capriles, José P. Rodrigues Furtado de Mendonça, Paul A. Slesinger, Kevin D. Costa, Hongyan Zou, Roland H. Friedel

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Asymmetric synthesis of stereogenic-at-iridium(III) complexes through Pd-catalyzed kinetic resolution by Yun-Peng Chu, Xue-Lin Yue, De-Hai Liu, Chuanyong Wang, Jiajia Ma

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Atlantic overturning inferred from air-sea heat fluxes indicates no decline since the 1960s by Jens Terhaar, Linus Vogt, Nicholas P. Foukal

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Impact of population screening for Lynch syndrome insights from the All of Us data by Jiheum Park, Hemanth Karnati, Sheila D. Rustgi, Chin Hur, Xiao-Fei Kong, Fay Kastrinos

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Spatial control of doping in conducting polymers enables complementary, conformable, implantable internal ion-gated organic electrochemical transistors by Duncan J. Wisniewski, Liang Ma, Onni J. Rauhala, Claudia Cea, Zifang Zhao, Alexander Ranschaert, Jennifer N. Gelinas, Dion Khodagholy

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Versatile nitrate-respiring heterotrophs are previously concealed contributors to sulfur cycle by Bo Shao, Yuan-Guo Xie, Long Zhang, Yang Ruan, Bin Liang, Ruochen Zhang, Xijun Xu, Wei Wang, Zhengda Lin, Xuanyuan Pei, Xueting Wang, Lei Zhao, Xu Zhou, Xiaohui Wu, Defeng Xing, Aijie Wang, Duu-Jong Lee, Nanqi Ren, Donald E. Canfield, Brian P. Hedlund, Zheng-Shuang Hua, Chuan Chen

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Sun-simulated-driven production of high-purity methanol from carbon dioxide by Jiqing Jiao, Yanbin Ma, Xiaoqian Han, Awu Ergu, Chao Zhang, Pingping Chen, Wei Liu, Qiquan Luo, Zhaolin Shi, Han Xu, Chen Chen, Yaguang Li, Tongbu Lu

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Chemical-guided SHAPE sequencing (cgSHAPE-seq) informs the binding site of RNA-degrading chimeras targeting SARS-CoV-2 5’ untranslated region by Zhichao Tang, Shalakha Hegde, Siyuan Hao, Manikandan Selvaraju, Jianming Qiu, Jingxin Wang

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Centrosome amplification and aneuploidy driven by the HIV-1-induced Vpr•VprBP•Plk4 complex in CD4+ T cells by Jung-Eun Park, Tae-Sung Kim, Yan Zeng, Melissa Mikolaj, Jong Il Ahn, Muhammad S. Alam, Christina M. Monnie, Victoria Shi, Ming Zhou, Tae-Wook Chun, Frank Maldarelli, Kedar Narayan, Jinwoo Ahn, Jonathan D. Ashwell, Klaus Strebel, Kyung S. Lee

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