Public Understanding and Expectations of Digital Health Evidence Generation: Focus Group Study by Paulina Bondaronek, Jingfeng Li, Henry W W Potts

“…However, as the perceived risk of an app increased, there was a noticeable shift toward preferring evidence from authoritative sources, such as government or National Health Service endorsements. ConclusionsThe public have a preference for evidence that resonates on a personal level, but also show a heightened demand for authoritative guidance as the potential risk of digital health interventions increases. …”
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Budget Impact of RefluxStop™ as a Treatment for Patients with Refractory Gastro-oesophageal Reflux Disease in the United Kingdom by Sam Harper, Lukasz Grodzicki, Stuart Mealing, Elizabeth Gemmill, Paul Goldsmith, Ahmed Ahmed

“…The current analysis aimed to describe the budget impact of introducing RefluxStop™ within National Health Service (NHS) England and Wales. **Objectives:** To estimate the more immediate, short-term clinical and economic effects of introducing RefluxStop™ as a therapeutic option for patients with GORD treated within NHS England and Wales. …”
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Design and validation of a new Healthcare Systems Usability Scale (HSUS) for clinical decision support systems: a mixed-methods approach by Peter J Watkinson, Abir Ghorayeb, Julie L Darbyshire, Marta W Wronikowska

“…Pilot testing established construct validity using factor analysis and facilitated estimates for reliability and internal consistency using the Cronbach’s alpha coefficient.Setting Two hospitals within a single National Health Service Trust.Participants We recruited a panel of 7 experts in usability and questionnaire writing for health purposes to test content validity; 10 participants to assess face validity and 78 participants for the pilot testing. …”
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Using systems mapping within the process evaluation of a randomised controlled trial of the ACE active ageing programme in England and Wales by Helen Hawley-Hague, Colin Greaves, Diane Crone, Afroditi Stathi, Nick Cavill, Amy Davies, Katie E Chatwin, Zsofia Szekeres, Janet Withall, Janice Thompson

“…These involved over 100 participants, volunteers and stakeholders (from National Health Service, statutory and voluntary sectors). …”
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A simulation study to quantitatively assess the performance of electronic prescribing systems in English NHS Hospital Trusts by Stephanie Klein, Athanasios Tsanas, Jamie Coleman, Rebecca Osselton, Jude Heed, Ann Slee, Neil Watson

“…Anyone who routinely prescribes medication could benefit from digitally assisted automated checks to identify whether a prescription should potentially not be allowed (e.g. drug allergy). National Health Service (NHS) Trusts have implemented a range of EP systems; however, their performance has not hitherto been evaluated. …”
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Telehealth and people with disabilities in the United Kingdom: a scoping review by Mezhen Ko, Mezhen Ko, Matthew Azzopardi, Constantinos Loizou, Abison Logeswaran, Benjamin Ng, Agata Pacho, Yu Jeat Chong

“…This scoping review explores the needs, experiences, and difficulties people with disabilities face when accessing telehealth services in the United Kingdom’s (UK) National Health Service (NHS).MethodsA systematic search was conducted using the PRISMA for Scoping Reviews (PRISMA-ScR) guidelines. …”
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Improving influenza vaccine uptake in clinical risk groups: patient, provider and commissioner perspectives on the acceptability and feasibility of expanding delivery pathways in E... by Sandra Mounier-Jack, Rajeka Lazarus, Ben Kasstan, Ifra Ali

“…Phase II consisted of semi-structured interviews with 50 healthcare providers based in National Health Service primary and secondary care settings, and influenza vaccine commissioners and programme managers. …”
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Evaluation of the digital diabetes prevention programme pilot: uncontrolled mixed-methods study protocol by William Henley, Elizabeth Murray, Kerry Daff, Anthi Lavida, Jenny Irwin, Jonathan Valabhji

“…Introduction The prevalence of type 2 diabetes is rising steeply. National Health Service England (NHSE) is exploring the potential of a digital diabetes prevention programme (DDPP) and has commissioned a pilot with embedded evaluation.Methods and analysis This study aims to determine whether, and if so, how, should NHSE implement a national DDPP, using a mixed-methods pretest and post-test design, underpinned by two theoretical frameworks: the Coventry, Aberdeen and London - Refined (CALO-RE) taxonomy of behavioural change techniques for the digital interventions and the Consolidated Framework for Implementation Research (CFIR) for implementation processes. …”
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Health-care resource use and costs associated with inflammatory bowel disease in northwest London: a retrospective linked database study by Zia UI-Haq, Luiz Causin, Tahereh Kamalati, Durgesh Kahol, Trishan Vaikunthanathan, Charlotte Wong, Naila Arebi

“…We performed a descriptive analysis of health-care data for IBD management in the National Health Service to explore potential areas for improvement. …”
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Cost-effectiveness Analysis of Hypoallergenic Milk Formulas for the Management of Cow’s Milk Protein Allergy in the United Kingdom by Rui Martins, Mark P. Connolly, Eleanor Minshall

“…Amino acid-based formula (AAF), extensively hydrolysed casein formula containing Lactobacillus rhamnosus Gorbach Goldin (EHCF+LGG), extensively hydrolysed whey formula (EHWF), and soy formula (SF) were compared using the National Health Service (NHS) perspective, 3-year time horizon and 3.5% discount rate for cost and health consequences. …”
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What are the lived healthcare experiences of patients with primary sclerosing cholangitis? A community-based qualitative interview study by Sheila Greenfield, Gideon Hirschfield, Jayne Parry, Katherine Arndtz, Madeline Cameron

“…Inclusion criteria were as follows: adults, self-identifying as having a diagnosis of PSC, and currently under National Health Service treatment for this disease. Patients with a history of liver transplantation were excluded.Results Participants confirmed the ongoing physical and psychological burden of PSC and its related healthcare. …”
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Cardiovascular risk profiles and the uptake of the NHS Healthcheck programme in male prisoners in six UK prisons: an observational cross-sectional survey by Kamlesh Khunti, Richard Morriss, Christopher Packham, Elizabeth Butcher, Marie Williams, Joanne Miksza

“…Introduction Half of all deaths in custody are due to natural causes, the most common being cardiovascular disease (CVD). National Health Service Healthchecks should be available to all eligible prisoners; it is not clear who receives them. …”
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Cohort study evaluating pressure ulcer management in clinical practice in the UK following initial presentation in the community: costs and outcomes by Julian F Guest, Graham W Fuller, Peter Vowden, Kathryn Ruth Vowden

“…Objectives The aim of this study was to estimate the patterns of care and annual levels of healthcare resource use attributable to managing pressure ulcers (PUs) in clinical practice in the community by the UK’s National Health Service (NHS), and the associated costs of patient management.Methods This was a retrospective cohort analysis of the records of 209 patients identified within a randomly selected population of 6000 patients with any type of wound obtained from The Health Improvement Network (THIN) Database, who developed a PU in the community and excluded hospital-acquired PUs. …”
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Perceptions and experiences of healthcare professionals of implementing the Organ Donation (Deemed Consent) Act in England during the Covid-19 pandemic by Mustafa Al-Haboubi, Leah McLaughlin, Lorraine Williams, Jane Noyes, Stephen O’Neill, Paul Boadu, Jennifer Bostock, Nicholas Mays

“…Conclusions Implementation could have been more impactful if delayed. The National Health Service needs to reprioritise organ donation and relaunch the implementation plan in the post-pandemic period, though it is unlikely the changes will bring about a significant increase in consent rates.…”
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Prioritizing Patients from the Most Deprived Areas on Elective Waiting Lists in the NHS in England: Estimating the Health and Health Inequality Impact by Naomi Kate Gibbs, Susan Griffin, Nils Gutacker, Adrián Villaseñor, Simon Walker

“…Reducing hospital waiting lists for elective procedures is a policy concern in the National Health Service (NHS) in England. Following growth in waiting lists after COVID-19, the NHS published an elective recovery plan that includes an aim to prioritize patients from deprived areas. …”
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Experience of induction of labour: a cross-sectional postnatal survey of women at UK maternity units by Helen Cheyne, Christine McCourt, Dharmintra Pasupathy, Julia Sanders, Sarah Jane Stock, Mairead Black, Cassandra Yuill, Mairi Harkness, Neelam Heera, Chlorice Wallace

“…The questionnaire was administered online and included fixed response and free-text options.Setting National Health Service maternity units in the UK.Participants 309 women who had an IOL.Outcome measures The primary outcome measure was experience of IOL. …”
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Adverse drug reactions, multimorbidity and polypharmacy: a prospective analysis of 1 month of medical admissions by Girvan Burnside, Munir Pirmohamed, Rostam Osanlou, Dyfrig A Hughes, Lauren Walker

“…Objective To ascertain the burden and associated cost of adverse drug reactions (ADRs), polypharmacy and multimorbidity through a prospective analysis of all medical admissions to a large university teaching hospital over a 1-month period.Design Prospective observational study.Setting Liverpool University Hospital Foundation National Health Service (NHS) Trust, England.Participants All medical admissions with greater than 24-hour stay over a 1-month period.Main outcome measures Prevalence of admissions due to an ADR and associated mortality, prevalence and association of multimorbidity and polypharmacy with ADRs, and estimated local financial cost of admissions where an ADR was a contributing or main reason for admission with projected costs for NHS in England.Results There were 218 identified patient admissions with an ADR giving a prevalence of 18.4%. …”
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Outcomes of cataract surgery training among ophthalmology trainees in the independent sector and within the NHS by Darren Shu Jeng Ting, Philip Severn, Qasim Mansoor, Yunzi Chen, Oonagh Crothers

“…Objective The surge in National Health Service (NHS) cataract procedures in the independent sector (IS) has reduced opportunities for cataract surgical training among ophthalmology trainees. …”
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Understanding recruitment to a perioperative randomised controlled trial: protocol for a mixed-methods substudy nested within a feasibility trial of octreotide infusion during live... by Duncan Wagstaff, S Ramani Moonesinghe, Jez Fabes, Michael Spiro, Edgar Brodkin, Ee-Neng Loh, Vivienne Hannon

“…This is a substudy within a feasibility randomised controlled trial of octreotide infusion during liver transplantation at two National Health Service hospitals, which will evaluate patient and staff experiences of trial processes. …”
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Anti-ceramide antibody and sphingosine-1-phosphate as potential biomarkers of unresectable non-small cell lung cancer by Lilla Bűdi, Dániel Hammer, Rita Varga, Veronika Müller, Ádám Domonkos Tárnoki, Dávid László Tárnoki, Martina Mészáros, András Bikov, András Bikov, Péter Horváth

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